Result of FASTA (omim) for pF1KA1432
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1432, 791 aa
  1>>>pF1KA1432 791 - 791 aa - 791 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7568+/-0.000365; mu= 18.8841+/- 0.023
 mean_var=83.4293+/-16.912, 0's: 0 Z-trim(114.4): 11  B-trim: 0 in 0/50
 Lambda= 0.140416
 statistics sampled from 24207 (24218) to 24207 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.284), width:  16
 Scan time: 12.660

The best scores are:                                      opt bits E(85289)
XP_011516270 (OMIM: 610354) PREDICTED: RAB6A-GEF c ( 886) 5288 1081.6       0
XP_011516269 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1112) 5288 1081.6       0
XP_016870423 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7       0
XP_016870425 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7       0
XP_016870424 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7       0
NP_001193486 (OMIM: 610354) RAB6A-GEF complex part (1386) 5288 1081.7       0
XP_005251580 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1422) 5288 1081.7       0
NP_065880 (OMIM: 610354) RAB6A-GEF complex partner (1423) 5288 1081.7       0
NP_001129392 (OMIM: 610354) RAB6A-GEF complex part (1165) 3422 703.6 1.2e-201


>>XP_011516270 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (886 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5785.8  bits: 1081.6 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:96-886)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_011 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
          70        80        90       100       110       120     

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
         130       140       150       160       170       180     

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
         190       200       210       220       230       240     

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
         250       260       270       280       290       300     

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
         310       320       330       340       350       360     

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
         370       380       390       400       410       420     

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
         430       440       450       460       470       480     

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
         490       500       510       520       530       540     

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
         550       560       570       580       590       600     

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
         610       620       630       640       650       660     

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
         670       680       690       700       710       720     

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
         730       740       750       760       770       780     

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
         790       800       810       820       830       840     

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_011 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
         850       860       870       880      

>>XP_011516269 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (1112 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5784.3  bits: 1081.6 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:322-1112)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_011 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
             300       310       320       330       340       350 

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
             360       370       380       390       400       410 

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
             420       430       440       450       460       470 

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
             480       490       500       510       520       530 

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
             540       550       560       570       580       590 

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
             600       610       620       630       640       650 

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
             660       670       680       690       700       710 

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
             720       730       740       750       760       770 

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
             780       790       800       810       820       830 

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
             840       850       860       870       880       890 

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
             900       910       920       930       940       950 

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
             960       970       980       990      1000      1010 

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
            1020      1030      1040      1050      1060      1070 

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_011 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
            1080      1090      1100      1110  

>>XP_016870423 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (1308 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5783.3  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
       490       500       510       520       530       540       

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       550       560       570       580       590       600       

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       610       620       630       640       650       660       

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       670       680       690       700       710       720       

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       730       740       750       760       770       780       

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       790       800       810       820       830       840       

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       850       860       870       880       890       900       

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       910       920       930       940       950       960       

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       970       980       990      1000      1010      1020       

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
      1030      1040      1050      1060      1070      1080       

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
      1090      1100      1110      1120      1130      1140       

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
      1150      1160      1170      1180      1190      1200       

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
      1210      1220      1230      1240      1250      1260       

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
      1270      1280      1290      1300        

>>XP_016870425 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (1308 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5783.3  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
       490       500       510       520       530       540       

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       550       560       570       580       590       600       

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       610       620       630       640       650       660       

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       670       680       690       700       710       720       

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       730       740       750       760       770       780       

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       790       800       810       820       830       840       

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       850       860       870       880       890       900       

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       910       920       930       940       950       960       

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       970       980       990      1000      1010      1020       

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
      1030      1040      1050      1060      1070      1080       

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
      1090      1100      1110      1120      1130      1140       

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
      1150      1160      1170      1180      1190      1200       

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
      1210      1220      1230      1240      1250      1260       

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
      1270      1280      1290      1300        

>>XP_016870424 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (1308 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5783.3  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
       490       500       510       520       530       540       

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       550       560       570       580       590       600       

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       610       620       630       640       650       660       

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       670       680       690       700       710       720       

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       730       740       750       760       770       780       

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       790       800       810       820       830       840       

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       850       860       870       880       890       900       

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       910       920       930       940       950       960       

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       970       980       990      1000      1010      1020       

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
      1030      1040      1050      1060      1070      1080       

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
      1090      1100      1110      1120      1130      1140       

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
      1150      1160      1170      1180      1190      1200       

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
      1210      1220      1230      1240      1250      1260       

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
      1270      1280      1290      1300        

>>NP_001193486 (OMIM: 610354) RAB6A-GEF complex partner   (1386 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5782.9  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:596-1386)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
NP_001 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
         570       580       590       600       610       620     

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
         630       640       650       660       670       680     

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
         690       700       710       720       730       740     

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
         750       760       770       780       790       800     

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
         810       820       830       840       850       860     

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
         870       880       890       900       910       920     

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
         930       940       950       960       970       980     

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
         990      1000      1010      1020      1030      1040     

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
        1050      1060      1070      1080      1090      1100     

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
        1110      1120      1130      1140      1150      1160     

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
        1170      1180      1190      1200      1210      1220     

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
        1230      1240      1250      1260      1270      1280     

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
        1290      1300      1310      1320      1330      1340     

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
NP_001 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
        1350      1360      1370      1380      

>>XP_005251580 (OMIM: 610354) PREDICTED: RAB6A-GEF compl  (1422 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5782.8  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:632-1422)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
XP_005 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
             610       620       630       640       650       660 

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
             670       680       690       700       710       720 

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
             730       740       750       760       770       780 

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
             790       800       810       820       830       840 

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
             850       860       870       880       890       900 

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
             910       920       930       940       950       960 

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
             970       980       990      1000      1010      1020 

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
            1030      1040      1050      1060      1070      1080 

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
            1090      1100      1110      1120      1130      1140 

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
            1150      1160      1170      1180      1190      1200 

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
            1210      1220      1230      1240      1250      1260 

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
            1270      1280      1290      1300      1310      1320 

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
            1330      1340      1350      1360      1370      1380 

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
XP_005 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
            1390      1400      1410      1420  

>>NP_065880 (OMIM: 610354) RAB6A-GEF complex partner pro  (1423 aa)
 initn: 5288 init1: 5288 opt: 5288  Z-score: 5782.8  bits: 1081.7 E(85289):    0
Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:633-1423)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
NP_065 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
            610       620       630       640       650       660  

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
            670       680       690       700       710       720  

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
            730       740       750       760       770       780  

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
            790       800       810       820       830       840  

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
            850       860       870       880       890       900  

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
            910       920       930       940       950       960  

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
            970       980       990      1000      1010      1020  

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
           1030      1040      1050      1060      1070      1080  

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
           1090      1100      1110      1120      1130      1140  

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
           1150      1160      1170      1180      1190      1200  

              580       590       600       610       620       630
pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV
           1210      1220      1230      1240      1250      1260  

              640       650       660       670       680       690
pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR
           1270      1280      1290      1300      1310      1320  

              700       710       720       730       740       750
pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS
           1330      1340      1350      1360      1370      1380  

              760       770       780       790 
pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
       :::::::::::::::::::::::::::::::::::::::::
NP_065 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS
           1390      1400      1410      1420   

>>NP_001129392 (OMIM: 610354) RAB6A-GEF complex partner   (1165 aa)
 initn: 3422 init1: 3422 opt: 3422  Z-score: 3741.1  bits: 703.6 E(85289): 1.2e-201
Smith-Waterman score: 3422; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:633-1141)

                                             10        20        30
pF1KA1                               MSRYIPHPFLVVSVTLTSVSTENGITLKMP
                                     ::::::::::::::::::::::::::::::
NP_001 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP
            610       620       630       640       650       660  

               40        50        60        70        80        90
pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT
            670       680       690       700       710       720  

              100       110       120       130       140       150
pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL
            730       740       750       760       770       780  

              160       170       180       190       200       210
pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE
            790       800       810       820       830       840  

              220       230       240       250       260       270
pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV
            850       860       870       880       890       900  

              280       290       300       310       320       330
pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL
            910       920       930       940       950       960  

              340       350       360       370       380       390
pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA
            970       980       990      1000      1010      1020  

              400       410       420       430       440       450
pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF
           1030      1040      1050      1060      1070      1080  

              460       470       480       490       500       510
pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTG
           1090      1100      1110      1120      1130      1140  

              520       530       540       550       560       570
pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL
                                                                   
NP_001 NVDFMSLVQGELYFTPCIYTFCY                                     
           1150      1160                                          




791 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:50:21 2016 done: Sat Nov  5 06:50:23 2016
 Total Scan time: 12.660 Total Display time:  0.240

Function used was FASTA [36.3.4 Apr, 2011]
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