Result of FASTA (omim) for pF1KE1068
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1068, 577 aa
  1>>>pF1KE1068 577 - 577 aa - 577 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4039+/-0.000444; mu= 0.8804+/- 0.028
 mean_var=243.8104+/-50.226, 0's: 0 Z-trim(118.9): 18  B-trim: 396 in 1/53
 Lambda= 0.082139
 statistics sampled from 32239 (32257) to 32239 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.378), width:  16
 Scan time: 12.000

The best scores are:                                      opt bits E(85289)
NP_065827 (OMIM: 616480) protein hinderin isoform  ( 577) 3829 467.1 6.8e-131
XP_005258374 (OMIM: 616480) PREDICTED: protein hin ( 573) 3688 450.4 7.2e-126
XP_016881367 (OMIM: 616480) PREDICTED: protein hin ( 469) 3137 385.1 2.8e-106
XP_011524402 (OMIM: 616480) PREDICTED: protein hin ( 456) 2683 331.3 4.3e-90
XP_005258372 (OMIM: 616480) PREDICTED: protein hin ( 613) 2683 331.3 5.4e-90
XP_016881365 (OMIM: 616480) PREDICTED: protein hin ( 609) 2542 314.6 5.8e-85
XP_016881366 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79
XP_011524401 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79
XP_005258375 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79
NP_001309256 (OMIM: 616480) protein hinderin isofo ( 505) 1991 249.3 2.3e-65
XP_016881370 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51
XP_016881369 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51
XP_016881368 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51


>>NP_065827 (OMIM: 616480) protein hinderin isoform 1 [H  (577 aa)
 initn: 3829 init1: 3829 opt: 3829  Z-score: 2470.9  bits: 467.1 E(85289): 6.8e-131
Smith-Waterman score: 3829; 99.7% identity (100.0% similar) in 577 aa overlap (1-577:1-577)

               10        20        30        40        50        60
pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
       :.:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_065 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
              490       500       510       520       530       540

              550       560       570       
pF1KE1 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       :::::::::::::::::::::::::::::::::::::
NP_065 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
              550       560       570       

>>XP_005258374 (OMIM: 616480) PREDICTED: protein hinderi  (573 aa)
 initn: 3688 init1: 3688 opt: 3688  Z-score: 2380.7  bits: 450.4 E(85289): 7.2e-126
Smith-Waterman score: 3688; 99.6% identity (100.0% similar) in 557 aa overlap (21-577:17-573)

               10        20        30        40        50        60
pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
                           ::::::::::::::::::::::::::::::::::::::::
XP_005     MPDNIIVFSFMFSCVVSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
       :.:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_005 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
        300       310       320       330       340       350      

              370       380       390       400       410       420
pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
        360       370       380       390       400       410      

              430       440       450       460       470       480
pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
        420       430       440       450       460       470      

              490       500       510       520       530       540
pF1KE1 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
        480       490       500       510       520       530      

              550       560       570       
pF1KE1 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       :::::::::::::::::::::::::::::::::::::
XP_005 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
        540       550       560       570   

>>XP_016881367 (OMIM: 616480) PREDICTED: protein hinderi  (469 aa)
 initn: 3137 init1: 3137 opt: 3137  Z-score: 2029.0  bits: 385.1 E(85289): 2.8e-106
Smith-Waterman score: 3137; 99.6% identity (99.8% similar) in 469 aa overlap (109-577:1-469)

       80        90       100       110       120       130        
pF1KE1 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE
                                     . ::::::::::::::::::::::::::::
XP_016                               MNRVSEEKEVTEERLKAEQESFEKKIRQLE
                                             10        20        30

      140       150       160       170       180       190        
pF1KE1 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS
               40        50        60        70        80        90

      200       210       220       230       240       250        
pF1KE1 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD
              100       110       120       130       140       150

      260       270       280       290       300       310        
pF1KE1 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS
              160       170       180       190       200       210

      320       330       340       350       360       370        
pF1KE1 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE
              220       230       240       250       260       270

      380       390       400       410       420       430        
pF1KE1 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGWLLGTSSSIKKHQDPPNSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGWLLGTSSSIKKHQDPPNSG
              280       290       300       310       320       330

      440       450       460       470       480       490        
pF1KE1 ENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTA
              340       350       360       370       380       390

      500       510       520       530       540       550        
pF1KE1 SPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGM
              400       410       420       430       440       450

      560       570       
pF1KE1 HRTPEELEENQILEDIFFI
       :::::::::::::::::::
XP_016 HRTPEELEENQILEDIFFI
              460         

>>XP_011524402 (OMIM: 616480) PREDICTED: protein hinderi  (456 aa)
 initn: 2683 init1: 2683 opt: 2683  Z-score: 1738.4  bits: 331.3 E(85289): 4.3e-90
Smith-Waterman score: 2683; 99.5% identity (100.0% similar) in 410 aa overlap (1-410:1-410)

               10        20        30        40        50        60
pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
       :.:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
                                                                   
XP_011 RELVAEKQLTKPQELKLDMNGSDSGPSSFIVVLSVY                        
              430       440       450                              

>>XP_005258372 (OMIM: 616480) PREDICTED: protein hinderi  (613 aa)
 initn: 3802 init1: 2683 opt: 2683  Z-score: 1736.6  bits: 331.3 E(85289): 5.4e-90
Smith-Waterman score: 3707; 93.6% identity (93.9% similar) in 609 aa overlap (1-573:1-609)

               10        20        30        40        50        60
pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
       :.:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_005 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_005 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS
              370       380       390       400       410       420

                                        420       430       440    
pF1KE1 --------------------------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER
                                  :::::::::::::::::::::::::::::::::
XP_005 RELVAEKQLTKPQELKLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KE1 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KE1 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE
              550       560       570       580       590       600

          570       
pF1KE1 LEENQILEDIFFI
       :::::::::    
XP_005 LEENQILEDIFFI
              610   

>>XP_016881365 (OMIM: 616480) PREDICTED: protein hinderi  (609 aa)
 initn: 3661 init1: 2542 opt: 2542  Z-score: 1646.4  bits: 314.6 E(85289): 5.8e-85
Smith-Waterman score: 3566; 93.4% identity (93.7% similar) in 589 aa overlap (21-573:17-605)

               10        20        30        40        50        60
pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
                           ::::::::::::::::::::::::::::::::::::::::
XP_016     MPDNIIVFSFMFSCVVSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
       :.:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_016 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
        300       310       320       330       340       350      

              370       380       390       400       410          
pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_016 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS
        360       370       380       390       400       410      

                                        420       430       440    
pF1KE1 --------------------------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER
                                  :::::::::::::::::::::::::::::::::
XP_016 RELVAEKQLTKPQELKLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER
        420       430       440       450       460       470      

          450       460       470       480       490       500    
pF1KE1 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH
        480       490       500       510       520       530      

          510       520       530       540       550       560    
pF1KE1 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE
        540       550       560       570       580       590      

          570       
pF1KE1 LEENQILEDIFFI
       :::::::::    
XP_016 LEENQILEDIFFI
        600         

>>XP_016881366 (OMIM: 616480) PREDICTED: protein hinderi  (568 aa)
 initn: 3502 init1: 2383 opt: 2383  Z-score: 1545.0  bits: 295.8 E(85289): 2.6e-79
Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564)

          20        30        40        50        60        70     
pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS
                                     ::::::::::::::::.:::::::::::::
XP_016                               MSPKADVKLKTSRVTDASISMESLKGTGDS
                                             10        20        30

          80        90       100       110       120       130     
pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
              280       290       300       310       320       330

         380       390       400       410                         
pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN-------------------------
       :::::::::::::::::::::::::::::::::::                         
XP_016 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL
              340       350       360       370       380       390

                         420       430       440       450         
pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
              400       410       420       430       440       450

     460       470       480       490       500       510         
pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
              460       470       480       490       500       510

     520       530       540       550       560       570       
pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
              520       530       540       550       560        

>>XP_011524401 (OMIM: 616480) PREDICTED: protein hinderi  (568 aa)
 initn: 3502 init1: 2383 opt: 2383  Z-score: 1545.0  bits: 295.8 E(85289): 2.6e-79
Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564)

          20        30        40        50        60        70     
pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS
                                     ::::::::::::::::.:::::::::::::
XP_011                               MSPKADVKLKTSRVTDASISMESLKGTGDS
                                             10        20        30

          80        90       100       110       120       130     
pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
              280       290       300       310       320       330

         380       390       400       410                         
pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN-------------------------
       :::::::::::::::::::::::::::::::::::                         
XP_011 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL
              340       350       360       370       380       390

                         420       430       440       450         
pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
              400       410       420       430       440       450

     460       470       480       490       500       510         
pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
              460       470       480       490       500       510

     520       530       540       550       560       570       
pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
              520       530       540       550       560        

>>XP_005258375 (OMIM: 616480) PREDICTED: protein hinderi  (568 aa)
 initn: 3502 init1: 2383 opt: 2383  Z-score: 1545.0  bits: 295.8 E(85289): 2.6e-79
Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564)

          20        30        40        50        60        70     
pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS
                                     ::::::::::::::::.:::::::::::::
XP_005                               MSPKADVKLKTSRVTDASISMESLKGTGDS
                                             10        20        30

          80        90       100       110       120       130     
pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM
              280       290       300       310       320       330

         380       390       400       410                         
pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN-------------------------
       :::::::::::::::::::::::::::::::::::                         
XP_005 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL
              340       350       360       370       380       390

                         420       430       440       450         
pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW
              400       410       420       430       440       450

     460       470       480       490       500       510         
pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS
              460       470       480       490       500       510

     520       530       540       550       560       570       
pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_005 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
              520       530       540       550       560        

>>NP_001309256 (OMIM: 616480) protein hinderin isoform 2  (505 aa)
 initn: 3110 init1: 1991 opt: 1991  Z-score: 1294.6  bits: 249.3 E(85289): 2.3e-65
Smith-Waterman score: 3015; 92.2% identity (92.4% similar) in 501 aa overlap (109-573:1-501)

       80        90       100       110       120       130        
pF1KE1 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE
                                     . ::::::::::::::::::::::::::::
NP_001                               MNRVSEEKEVTEERLKAEQESFEKKIRQLE
                                             10        20        30

      140       150       160       170       180       190        
pF1KE1 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS
               40        50        60        70        80        90

      200       210       220       230       240       250        
pF1KE1 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD
              100       110       120       130       140       150

      260       270       280       290       300       310        
pF1KE1 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS
              160       170       180       190       200       210

      320       330       340       350       360       370        
pF1KE1 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE
              220       230       240       250       260       270

      380       390       400       410                            
pF1KE1 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYN----------------------------
       ::::::::::::::::::::::::::::::::                            
NP_001 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQELKLD
              280       290       300       310       320       330

                      420       430       440       450       460  
pF1KE1 --------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQ
                :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQ
              340       350       360       370       380       390

            470       480       490       500       510       520  
pF1KE1 KKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSP
              400       410       420       430       440       450

            530       540       550       560       570       
pF1KE1 NSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
       :::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_001 NSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
              460       470       480       490       500     




577 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:30:49 2016 done: Sat Nov  5 19:30:51 2016
 Total Scan time: 12.000 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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