Result of FASTA (omim) for pF1KB8996
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8996, 407 aa
  1>>>pF1KB8996 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0815+/-0.000325; mu= 2.7357+/- 0.021
 mean_var=243.5797+/-50.278, 0's: 0 Z-trim(123.8): 59  B-trim: 1426 in 1/59
 Lambda= 0.082178
 statistics sampled from 44312 (44374) to 44312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.52), width:  16
 Scan time:  6.490

The best scores are:                                      opt bits E(85289)
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 2859 351.3 2.5e-96
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426)  700 95.3   3e-19
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426)  700 95.3   3e-19
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483)  700 95.4 3.3e-19
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548)  700 95.4 3.6e-19
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352)  623 86.1 1.4e-16
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350)  552 77.7 4.9e-14
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240)  347 53.3 7.7e-07
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364)  350 53.8 8.2e-07
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396)  347 53.4 1.1e-06
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345)  328 51.1 4.8e-06
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345)  328 51.1 4.8e-06
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372)  328 51.2 5.1e-06
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408)  328 51.2 5.4e-06
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408)  328 51.2 5.4e-06
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408)  328 51.2 5.4e-06
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408)  328 51.2 5.4e-06
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431)  316 49.8 1.5e-05
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513)  312 49.4 2.4e-05
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472)  307 48.8 3.4e-05
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239)  298 47.5 4.3e-05
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455)  300 47.9 5.9e-05
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454)  298 47.7 6.9e-05
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450)  296 47.4 8.1e-05
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402)  293 47.1 9.6e-05
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427)  293 47.1  0.0001
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478)  292 47.0 0.00012
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424)  287 46.4 0.00016
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501)  284 46.1 0.00024
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501)  284 46.1 0.00024
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501)  284 46.1 0.00024
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214)  268 43.9 0.00047
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347)  268 44.0 0.00067
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412)  264 43.6  0.0011
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412)  264 43.6  0.0011
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390)  261 43.2  0.0013
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391)  261 43.2  0.0013
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429)  246 41.5  0.0048
NP_003229 (OMIM: 190220,614816) transforming growt ( 414)  238 40.5   0.009
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442)  238 40.6  0.0094


>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr  (407 aa)
 initn: 2859 init1: 2859 opt: 2859  Z-score: 1850.2  bits: 351.3 E(85289): 2.5e-96
Smith-Waterman score: 2859; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)

               10        20        30        40        50        60
pF1KB8 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM
              310       320       330       340       350       360

              370       380       390       400       
pF1KB8 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
              370       380       390       400       

>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr  (426 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 466.6  bits: 95.3 E(85289): 3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:22-426)

             20        30        40        50         60        70 
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
                                     : ::: : :    : ::.    :...   .
NP_002          MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
                        10        20        30        40        50 

              80        90       100       110       120       130 
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
NP_002 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
              60        70        80        90       100       110 

             140       150       160       170       180       190 
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
NP_002 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
             120          130       140       150       160        

             200                         210         220       230 
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
NP_002 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
           170       180       190       200       210       220   

             240       250       260                               
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
NP_002 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
           230       240       250       260       270       280   

        270       280        290       300       310       320     
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
NP_002 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
           290       300       310       320       330       340   

         330       340       350       360        370       380    
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
NP_002 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
           350       360       370       380       390       400   

          390       400       
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
       .::  ::.:.:. :::::::::.
NP_002 YDDGQNIIKKDIQNMIVEECGCS
           410       420      

>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A   (426 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 466.6  bits: 95.3 E(85289): 3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:22-426)

             20        30        40        50         60        70 
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
                                     : ::: : :    : ::.    :...   .
XP_016          MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
                        10        20        30        40        50 

              80        90       100       110       120       130 
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
              60        70        80        90       100       110 

             140       150       160       170       180       190 
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
             120          130       140       150       160        

             200                         210         220       230 
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
           170       180       190       200       210       220   

             240       250       260                               
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
           230       240       250       260       270       280   

        270       280        290       300       310       320     
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
           290       300       310       320       330       340   

         330       340       350       360        370       380    
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
           350       360       370       380       390       400   

          390       400       
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
       .::  ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
           410       420      

>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A   (483 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 465.9  bits: 95.4 E(85289): 3.3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:79-483)

             20        30        40        50         60        70 
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
                                     : ::: : :    : ::.    :...   .
XP_016 AITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
       50        60        70        80        90       100        

              80        90       100       110       120       130 
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
      110       120       130       140       150       160        

             140       150       160       170       180       190 
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
      170       180          190       200       210            220

             200                         210         220       230 
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
              230       240       250       260       270       280

             240       250       260                               
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
              290       300       310       320       330       340

        270       280        290       300       310       320     
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
              350       360       370       380       390       400

         330       340       350       360        370       380    
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
              410       420       430       440       450       460

          390       400       
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
       .::  ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
              470       480   

>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A   (548 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 465.2  bits: 95.4 E(85289): 3.6e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:144-548)

             20        30        40        50         60        70 
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
                                     : ::: : :    : ::.    :...   .
XP_016 AITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
           120       130       140       150       160       170   

              80        90       100       110       120       130 
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
           180       190       200       210       220       230   

             140       150       160       170       180       190 
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
           240       250          260       270       280          

             200                         210         220       230 
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
         290       300       310       320       330       340     

             240       250       260                               
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
         350       360       370       380       390       400     

        270       280        290       300       310       320     
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
         410       420       430       440       450       460     

         330       340       350       360        370       380    
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
         470       480       490       500       510       520     

          390       400       
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
       .::  ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
         530       540        

>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr  (352 aa)
 initn: 709 init1: 338 opt: 623  Z-score: 418.4  bits: 86.1 E(85289): 1.4e-16
Smith-Waterman score: 776; 38.3% identity (64.6% similar) in 373 aa overlap (42-407:14-352)

              20        30        40         50        60          
pF1KB8 ACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSP-GGSQDTCTSCGGFRRPE-ELGR
                                     :   ..: .:.:  : .:::   :  ::  
NP_005                  MTSSLLLAFLLLAPTTVATPRAGGQ--CPACGG---PTLELES
                                10        20          30           

      70        80        90       100       110       120         
pF1KB8 VDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGH
           .:. .:: ::..:..  ::.... : .::. :::..::.          .:.    
NP_005 QRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHG----------VPQ----
       40        50        60        70        80                  

     130       140       150        160        170       180       
pF1KB8 ASPGADGQERVSEIISFAETDGLAS-SRVRLYF-FISNEGNQNLFVVQASLWLYLKLLPY
       ..   :..:.  :::::::: ::.. ...:: : : :..   .  : :::: ....: : 
NP_005 GALLEDNREQECEIISFAET-GLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-PS
           90       100        110       120       130       140   

       190       200       210        220       230       240      
pF1KB8 VLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRV-DLKRSGWHTFPLTEAIQALFERGERRL
         .     :::: :      :.   ... . . ..  :::: .::    ::   .:.  :
NP_005 --NTTWTLKVRVLVL---GPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTL
              150          160       170       180       190       

        250       260       270       280       290       300      
pF1KB8 NLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQ
       .: .. .  :  ...      :  .:::::....:.: ..:.:..::..:.: . .::::
NP_005 ELVLEGQVAQSSVIL------GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQ
       200       210             220        230       240       250

        310       320       330       340       350       360      
pF1KB8 QFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG
       .::.::: :::.:::: : ::  :.: :.:: ..::.:: :.::::::.:  .  .   :
NP_005 EFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA-NTAAG
              260       270       280       290       300          

          370       380       390       400       
pF1KB8 TVN--SCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
       :..  :::.::    .:.::.: . :::: :.:.:.:: :::.
NP_005 TTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
     310       320       330       340       350  

>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr  (350 aa)
 initn: 627 init1: 278 opt: 552  Z-score: 372.9  bits: 77.7 E(85289): 4.9e-14
Smith-Waterman score: 668; 36.2% identity (59.9% similar) in 367 aa overlap (50-407:21-350)

      20        30        40        50        60        70         
pF1KB8 GWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVK
                                     :. ..: :::: .   .  :.    :: .:
NP_113           MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERAL--VLELAK
                         10        20        30        40          

      80        90       100       110       120       130         
pF1KB8 RHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQER
       ..::. :.. .:: :::  :.::.. :::.:. :.:               .:: .:.: 
NP_113 QQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSV---------------APG-NGEE-
       50        60        70        80                        90  

     140        150       160       170       180        190       
pF1KB8 VSEIISFAE-TDGLASSRVRLYFFISNEGNQNLFVVQASLWLY-LKLLPYVLEKGSRRKV
          .::::  ::. ..    : : .:.  ...:.  .: :::. :  :: .:     :  
NP_113 ---VISFATVTDSTSAYSSLLTFHLSTPRSHHLY--HARLWLHVLPTLPGTL---CLRIF
                100       110       120         130          140   

       200       210       220       230       240       250       
pF1KB8 RVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQE
       :     ..::  .:  ..:...     ::::. :  .  .:  :::.   : .: : :. 
NP_113 RWGPRRRRQG--SRTLLAEHHIT--NLGWHTLTLPSS--GL--RGEKSGVLKLQLD-CRP
           150         160         170           180       190     

        260           270        280        290       300       310
pF1KB8 L-AVVPVFVDP----GEESHR-PFVVVQARLGD-SRHRIRKRGLECDGRTNLCCRQQFFI
       : .   :  .:       .:. ::. .. : .. .  : :.:   :.  : ::::.. ..
NP_113 LEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYV
          200       210       220       230       240       250    

              320       330       340       350       360       370
pF1KB8 DFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNS
       ::. .:: :::. : ::  ::: :.:: .::: :: :.:::.:: .  .  .  :... :
NP_113 DFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAST-S
          260       270       280       290       300       310    

              380       390       400       
pF1KB8 CCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
       ::.::    .:.::.: . :.:: :::.:.:: :::.
NP_113 CCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
           320       330       340       350

>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b  (240 aa)
 initn: 329 init1: 186 opt: 347  Z-score: 243.8  bits: 53.3 E(85289): 7.7e-07
Smith-Waterman score: 354; 32.0% identity (59.6% similar) in 203 aa overlap (219-406:41-239)

      190       200       210       220       230       240        
pF1KB8 LEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNL
                                     :. . : :..: .: :..    .:.   ..
XP_011 FHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGF
               20        30        40        50        60        70

      250        260       270                280         290      
pF1KB8 DVQCDSCQE-LAVVPVFVDPGEESH---------RPFVVVQARLGDSR--HRIRKRGLEC
        :.    .:  .:    :  ..  :         ::..:. .. : ..  :. .::  . 
XP_011 VVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKH
               80        90       100       110       120       130

        300          310       320       330       340       350   
pF1KB8 DGRTNL---CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTA
         :  :   : :. ...::  .::::::.:: ::.. ::.: ::  ::      .: . :
XP_011 KQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLA---DHLNSTNHA
              140       150       160       170          180       

           360       370       380       390       400       
pF1KB8 VVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
       .: :  . ..:    ..::.::.::..::::.:.. ..: ..  .:.:: ::: 
XP_011 IV-QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
        190       200       210       220       230       240

>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d  (364 aa)
 initn: 370 init1: 198 opt: 350  Z-score: 243.3  bits: 53.8 E(85289): 8.2e-07
Smith-Waterman score: 350; 40.8% identity (64.1% similar) in 142 aa overlap (272-406:230-363)

             250       260       270       280       290           
pF1KB8 GERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKR-------GL
                                     :  ..::     :. :  :::        :
NP_065 LFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLN-PDQCHPSRKRRAAIPVPKL
     200       210       220       230        240       250        

          300       310       320       330       340       350    
pF1KB8 ECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAV
        :    ::: :.:.::.:: .::. ::::: :...:::.: ::  :. .  ..:..   .
NP_065 SC---KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLT-ISLNSSNY---A
      260          270       280       290       300        310    

          360       370       380       390       400       
pF1KB8 VNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
         :  :....:   .. ::::::: .:::: :.. :.. :   .:.:.:::: 
NP_065 FMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
             320       330       340       350       360    

>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene  (396 aa)
 initn: 354 init1: 186 opt: 347  Z-score: 240.9  bits: 53.4 E(85289): 1.1e-06
Smith-Waterman score: 397; 26.1% identity (56.5% similar) in 356 aa overlap (73-406:48-395)

             50        60        70        80        90        100 
pF1KB8 PPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITH-AVPKA
                                     . :   . ..:: . .. ::. .. ::   
NP_001 LGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPP
        20        30        40        50        60        70       

             110       120       130       140       150       160 
pF1KB8 AMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYF
        :.   :. :.:.    :     :   .:.  :.  .   .  :. :    ... .: .:
NP_001 YMLDLYRR-HSGQ---PGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFF
        80            90       100       110       120       130   

             170       180       190       200         210         
pF1KB8 FISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVY--FQEQGHGDRW---NMVE
       :  .    . :...: : .. . .  .: ..:  . :...:  ..    ....    ...
NP_001 FNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLD
           140       150       160       170       180       190   

         220       230       240       250       260            270
pF1KB8 KR-VDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVP---VFVDPG--EE
        : :. . : :..: .: :..    .:.   .. :.    .:   :    : .. .  ..
NP_001 TRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQD
           200       210       220       230       240       250   

                   280         290       300          310       320
pF1KB8 SH-----RPFVVVQARLGDSR--HRIRKRGLECDGRTNL---CCRQQFFIDFRLIGWNDW
        :     ::..:. .. : ..  :. .::  .   :  :   : :. ...::  .:::::
NP_001 EHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDW
           260       270       280       290       300       310   

              330       340       350       360       370       380
pF1KB8 IIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTM
       :.:: ::.. ::.: ::  ::      .: . :.: :  . ..:    ..::.::.::..
NP_001 IVAPPGYHAFYCHGECPFPLAD---HLNSTNHAIV-QTLVNSVNSKIPKACCVPTELSAI
           320       330          340        350       360         

              390       400       
pF1KB8 SMLYFDDEYNIVKRDVPNMIVEECGCA
       ::::.:.. ..: ..  .:.:: ::: 
NP_001 SMLYLDENEKVVLKNYQDMVVEGCGCR
     370       380       390      




407 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:52:22 2016 done: Sat Nov  5 00:52:23 2016
 Total Scan time:  6.490 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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