Result of FASTA (omim) for pF1KB7811
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7811, 529 aa
  1>>>pF1KB7811 529 - 529 aa - 529 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.2622+/-0.000339; mu= -9.4452+/- 0.021
 mean_var=281.1587+/-58.194, 0's: 0 Z-trim(123.2): 12  B-trim: 51 in 1/57
 Lambda= 0.076489
 statistics sampled from 42611 (42623) to 42611 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.5), width:  16
 Scan time: 12.380

The best scores are:                                      opt bits E(85289)
NP_005517 (OMIM: 140580) heat shock factor protein ( 529) 3512 400.7 5.6e-111
XP_016868866 (OMIM: 140580) PREDICTED: heat shock  ( 489) 3065 351.4 3.7e-96
XP_005272373 (OMIM: 140580) PREDICTED: heat shock  ( 517) 2531 292.5 2.1e-78
XP_005272372 (OMIM: 140580) PREDICTED: heat shock  ( 557) 2531 292.5 2.3e-78
XP_005272374 (OMIM: 140580) PREDICTED: heat shock  ( 310) 1909 223.7 6.3e-58
XP_011515306 (OMIM: 140580) PREDICTED: heat shock  ( 346) 1127 137.5 6.5e-32
XP_011515308 (OMIM: 140580) PREDICTED: heat shock  ( 272) 1041 127.9 3.8e-29
NP_001035757 (OMIM: 116800,602438) heat shock fact ( 492)  925 115.2 4.5e-25
NP_001529 (OMIM: 116800,602438) heat shock factor  ( 462)  890 111.4 6.3e-24
NP_001129036 (OMIM: 140581) heat shock factor prot ( 518)  837 105.5   4e-22
NP_004497 (OMIM: 140581) heat shock factor protein ( 536)  837 105.5 4.1e-22
NP_001230023 (OMIM: 140581) heat shock factor prot ( 230)  825 104.0 4.9e-22


>>NP_005517 (OMIM: 140580) heat shock factor protein 1 [  (529 aa)
 initn: 3512 init1: 3512 opt: 3512  Z-score: 2113.4  bits: 400.7 E(85289): 5.6e-111
Smith-Waterman score: 3512; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS
              430       440       450       460       470       480

              490       500       510       520         
pF1KB7 VDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
              490       500       510       520         

>>XP_016868866 (OMIM: 140580) PREDICTED: heat shock fact  (489 aa)
 initn: 3106 init1: 3060 opt: 3065  Z-score: 1847.4  bits: 351.4 E(85289): 3.7e-96
Smith-Waterman score: 3065; 98.3% identity (98.7% similar) in 472 aa overlap (1-472:1-472)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGS
       :::::::::::::::::::::::::::::::::::::::::.  :   .: :        
XP_016 SVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSAGALHSAAAVPAGPRLRGH
              430       440       450       460       470       480

              490       500       510       520         
pF1KB7 VDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
                                                        
XP_016 REQRPAGAV                                        
                                                        

>>XP_005272373 (OMIM: 140580) PREDICTED: heat shock fact  (517 aa)
 initn: 3040 init1: 2531 opt: 2531  Z-score: 1528.5  bits: 292.5 E(85289): 2.1e-78
Smith-Waterman score: 2993; 92.6% identity (93.2% similar) in 500 aa overlap (1-472:1-500)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
              310       320       330       340       350       360

              370       380                                   390  
pF1KB7 PPSPPPTSTPEKCLSVACLDK----------------------------NELSDHLDAMD
       ::::::::::::::::::::.                            :::::::::::
XP_005 PPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELSDHLDAMD
              370       380       390       400       410       420

            400       410       420       430       440       450  
pF1KB7 SNLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPP
              430       440       450       460       470       480

            460       470       480       490       500       510  
pF1KB7 EAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTI
       :::::::::.  :   .: :                                        
XP_005 EAENSSPDSAGALHSAAAVPAGPRLRGHREQRPAGAV                       
              490       500       510                              

>>XP_005272372 (OMIM: 140580) PREDICTED: heat shock fact  (557 aa)
 initn: 3492 init1: 2531 opt: 2531  Z-score: 1528.0  bits: 292.5 E(85289): 2.3e-78
Smith-Waterman score: 3440; 94.8% identity (95.0% similar) in 557 aa overlap (1-529:1-557)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
              310       320       330       340       350       360

              370       380                                   390  
pF1KB7 PPSPPPTSTPEKCLSVACLDK----------------------------NELSDHLDAMD
       ::::::::::::::::::::.                            :::::::::::
XP_005 PPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELSDHLDAMD
              370       380       390       400       410       420

            400       410       420       430       440       450  
pF1KB7 SNLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPP
              430       440       450       460       470       480

            460       470       480       490       500       510  
pF1KB7 EAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTI
              490       500       510       520       530       540

            520         
pF1KB7 SLLTGSEPPKAKDPTVS
       :::::::::::::::::
XP_005 SLLTGSEPPKAKDPTVS
              550       

>>XP_005272374 (OMIM: 140580) PREDICTED: heat shock fact  (310 aa)
 initn: 1909 init1: 1909 opt: 1909  Z-score: 1161.0  bits: 223.7 E(85289): 6.3e-58
Smith-Waterman score: 1909; 99.7% identity (99.7% similar) in 288 aa overlap (1-288:1-288)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEE
       :::::::::::::::::::::::::::::::::::::::::::::: :            
XP_005 SAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDESPHGRQGPHGHRGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGR
                                                                   
XP_005 ASLPPAHLHP                                                  
              310                                                  

>>XP_011515306 (OMIM: 140580) PREDICTED: heat shock fact  (346 aa)
 initn: 2088 init1: 1127 opt: 1127  Z-score: 693.9  bits: 137.5 E(85289): 6.5e-32
Smith-Waterman score: 2036; 91.6% identity (91.9% similar) in 346 aa overlap (212-529:1-346)

             190       200       210       220       230       240 
pF1KB7 QQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPYS
                                     ::::::::::::::::::::::::::::::
XP_011                               MLNDSGSAHSMPKYSRQFSLEHVHGSGPYS
                                             10        20        30

             250       260       270       280       290       300 
pF1KB7 APSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEP
               40        50        60        70        80        90

             310       320       330       340       350       360 
pF1KB7 PSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGRP
              100       110       120       130       140       150

             370       380                                   390   
pF1KB7 PSPPPTSTPEKCLSVACLDK----------------------------NELSDHLDAMDS
       :::::::::::::::::::.                            ::::::::::::
XP_011 PSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELSDHLDAMDS
              160       170       180       190       200       210

           400       410       420       430       440       450   
pF1KB7 NLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPE
              220       230       240       250       260       270

           460       470       480       490       500       510   
pF1KB7 AENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTIS
              280       290       300       310       320       330

           520         
pF1KB7 LLTGSEPPKAKDPTVS
       ::::::::::::::::
XP_011 LLTGSEPPKAKDPTVS
              340      

>>XP_011515308 (OMIM: 140580) PREDICTED: heat shock fact  (272 aa)
 initn: 1592 init1: 975 opt: 1041  Z-score: 644.2  bits: 127.9 E(85289): 3.8e-29
Smith-Waterman score: 1540; 89.3% identity (89.7% similar) in 271 aa overlap (287-529:2-272)

        260       270       280       290       300       310      
pF1KB7 AVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPPQSPRVEEASPG
                                     ::::::::::::::::::::::::::::::
XP_011                              MRPLSSSPLVRVKEEPPSPPQSPRVEEASPG
                                            10        20        30 

        320       330       340       350       360       370      
pF1KB7 RPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGRPPSPPPTSTPEKCLSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTDTEGRPPSPPPTSTPEKCLSV
              40        50        60        70        80        90 

        380                                   390       400        
pF1KB7 ACLDK----------------------------NELSDHLDAMDSNLDNLQTMLSSHGFS
       ::::.                            :::::::::::::::::::::::::::
XP_011 ACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELSDHLDAMDSNLDNLQTMLSSHGFS
             100       110       120       130       140       150 

      410       420       430       440       450       460        
pF1KB7 VDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHY
             160       170       180       190       200       210 

      470       480       490       500       510       520        
pF1KB7 TAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTV
             220       230       240       250       260       270 

        
pF1KB7 S
       :
XP_011 S
        

>>NP_001035757 (OMIM: 116800,602438) heat shock factor p  (492 aa)
 initn: 738 init1: 587 opt: 925  Z-score: 571.1  bits: 115.2 E(85289): 4.5e-25
Smith-Waterman score: 1001; 41.2% identity (62.8% similar) in 473 aa overlap (7-475:9-453)

                 10        20        30        40        50        
pF1KB7   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB7 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB7 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
NP_001 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
                 130       140       150       160       170       

      180       190       200        210       220       230       
pF1KB7 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
NP_001 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       180       190       200       210        220       230      

       240       250       260       270       280       290       
pF1KB7 GPYSAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRV
        ::   ::   ..   .:    . ::::::: : .:.   .  . : : :    . :. .
NP_001 DPYFIQSPLPETNLGLSPHR--ARGPIISDIPEDSPSPEGTRLSPSSDGR--REKGLALL
        240       250         260       270       280         290  

       300       310       320       330       340        350      
pF1KB7 KEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAP-ASVTALTDARGHTD
       ::::           ::::  . .   :.:.   :  .    : : : : :. ...:  .
NP_001 KEEP-----------ASPGGDGEAGLALAPNEC-DFCVTAPPPLPVAVVQAILEGKGSFS
                       300       310        320       330       340

        360       370       380       390         400       410    
pF1KB7 TEGRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNL--QTMLSSHGFSVDTSAL
        ::    :  .. ::        :.. :.  :.. : . ..:    .:.    ::. .. 
NP_001 PEG----PRNAQQPEPGDPREIPDRGPLG--LESGDRSPESLLPPMLLQPPQESVEPAGP
                  350       360         370       380       390    

          420       430       440       450       460       470    
pF1KB7 LDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLF
       ::...::.   . .: :::  :. .: :.  .  :.      .::. ::.     . ::.
NP_001 LDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKD--PTLGAPLL
          400       410       420       430       440         450  

          480       490       500       510       520         
pF1KB7 LLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
       :                                                      
NP_001 LDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP               
            460       470       480       490                 

>>NP_001529 (OMIM: 116800,602438) heat shock factor prot  (462 aa)
 initn: 728 init1: 587 opt: 890  Z-score: 550.6  bits: 111.4 E(85289): 6.3e-24
Smith-Waterman score: 902; 39.1% identity (58.2% similar) in 471 aa overlap (7-475:9-423)

                 10        20        30        40        50        
pF1KB7   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB7 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB7 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
NP_001 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
                 130       140       150       160       170       

      180       190       200        210       220       230       
pF1KB7 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
NP_001 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       180       190       200       210        220       230      

       240       250       260        270       280       290      
pF1KB7 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPGGSIDERPLSSSPLVR
        ::   ::.  : :     :.: .::   :..:      :. .::           : : 
NP_001 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPG---------FLPPVM
        240       250       260       270       280                

        300       310       320       330       340       350      
pF1KB7 VKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTD
       .   :: :     :.    :. :     .::    ..    ..: :..   . : ::   
NP_001 AGAPPPLPVAV--VQAILEGKGS-----FSP----EGPRNAQQPEPGDPREIPD-RGPLG
       290         300            310           320       330      

        360       370       380       390       400       410      
pF1KB7 TEGRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLD
        :.   ::     :                              .:.    ::. .. ::
NP_001 LESGDRSPESLLPP-----------------------------MLLQPPQESVEPAGPLD
         340                                    350       360      

        420       430       440       450       460       470      
pF1KB7 LFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLL
       ...::.   . .: :::  :. .: :.  .  :.      .::. ::.     . ::.: 
NP_001 VLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKD--PTLGAPLLLD
        370       380       390       400       410         420    

        480       490       500       510       520         
pF1KB7 DPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
                                                            
NP_001 VQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP               
          430       440       450       460                 

>>NP_001129036 (OMIM: 140581) heat shock factor protein   (518 aa)
 initn: 1001 init1: 493 opt: 837  Z-score: 518.2  bits: 105.5 E(85289): 4e-22
Smith-Waterman score: 957; 39.4% identity (65.2% similar) in 477 aa overlap (13-480:5-439)

               10        20        30        40        50        60
pF1KB7 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
                   :::::::.:::::: .  :. .: :: .:.:: :.:. .::::.::::
NP_001         MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
                       10        20        30        40        50  

               70        80        90        100       110         
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
       ::::::::::::::::::::::::..: .:: :::  .::::: : .::..:::::::::
NP_001 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
             60        70         80        90       100       110 

     120       130       140       150       160       170         
pF1KB7 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
       .:    : :. ::::...::.....: .. ::: ..:.:  .: :::.::.::. :: ::
NP_001 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
                120       130       140       150       160        

     180       190       200       210       220       230         
pF1KB7 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
       ::::.:. :..::...:::.:.....::: ::.:: .:. .   :   :  ...   .  
NP_001 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
      170       180       190       200          210       220     

     240       250       260             270       280       290   
pF1KB7 YSAPSPAYSSSSLYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSP
       ...:   .: .    :    :.  :: :.:      :  :. : ..     :    :. :
NP_001 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
            230       240       250       260       270       280  

           300       310       320       330       340       350   
pF1KB7 LVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARG
        . . :.      .: .. .  ..:.  ..: : .   :.    : :  .:.. :. . .
NP_001 DIVIVEDDNEDEYAPVIQSGEQNEPAR-ESLSSGS---DG----SSPLMSSAVQLNGSSS
            290       300        310              320       330    

           360       370         380       390       400       410 
pF1KB7 HTDTEGRPPSPPPTSTPEKCLS--VACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDT
        :       :  :..  .. :.  .  : : :: :.::..: .:...:.:::.. ::.: 
NP_001 LT-------SEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDP
                 340       350       360       370       380       

             420       430       440       450       460       470 
pF1KB7 SALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQ
       . :.:  . .          :...  .. . .:  :  :  .   :.::  :::..::: 
NP_001 DLLVDSENKG----------LETTKNNVVQPVS--EEGRKSK---SKPD--KQLIQYTAF
       390                 400       410            420         430

             480       490       500       510       520           
pF1KB7 PLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS  
       ::. .  :.                                                   
NP_001 PLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTE
              440       450       460       470       480       490




529 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:39:32 2016 done: Fri Nov  4 22:39:34 2016
 Total Scan time: 12.380 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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