Result of FASTA (omim) for pF1KB7665
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7665, 337 aa
  1>>>pF1KB7665 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3783+/-0.000384; mu= 2.3411+/- 0.024
 mean_var=180.9146+/-37.397, 0's: 0 Z-trim(119.0): 60  B-trim: 294 in 1/56
 Lambda= 0.095354
 statistics sampled from 32485 (32559) to 32485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.382), width:  16
 Scan time:  9.220

The best scores are:                                      opt bits E(85289)
NP_036391 (OMIM: 604674) hairy/enhancer-of-split r ( 337) 2193 313.7 3.7e-85
XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
NP_036390 (OMIM: 602953) hairy/enhancer-of-split r ( 304)  858 130.0 6.5e-30
NP_001035798 (OMIM: 602953) hairy/enhancer-of-spli ( 308)  840 127.5 3.6e-29
NP_055386 (OMIM: 609034) hairy/enhancer-of-split r ( 328)  752 115.4 1.7e-25
XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhan ( 300)  683 105.9 1.1e-22
NP_001269780 (OMIM: 602953) hairy/enhancer-of-spli ( 214)  400 66.9 4.5e-11
NP_005515 (OMIM: 139605) transcription factor HES- ( 280)  335 58.0 2.8e-08
NP_066993 (OMIM: 608060) transcription factor HES- ( 221)  290 51.8 1.7e-06
NP_001135939 (OMIM: 608060) transcription factor H ( 247)  282 50.7 3.9e-06
NP_061115 (OMIM: 610331) transcription cofactor HE ( 224)  210 40.8  0.0035
NP_001136325 (OMIM: 610331) transcription cofactor ( 222)  205 40.1  0.0055
NP_115969 (OMIM: 608059,613686) transcription fact ( 225)  201 39.5  0.0082
NP_061962 (OMIM: 609970) transcription factor HES- ( 173)  197 38.9  0.0097


>>NP_036391 (OMIM: 604674) hairy/enhancer-of-split relat  (337 aa)
 initn: 2193 init1: 2193 opt: 2193  Z-score: 1649.9  bits: 313.7 E(85289): 3.7e-85
Smith-Waterman score: 2193; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)

               10        20        30        40        50        60
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 PSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAA
              250       260       270       280       290       300

              310       320       330       
pF1KB7 TAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
       :::::::::::::::::::::::::::::::::::::
NP_036 TAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
              310       320       330       

>>XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 1903 init1: 1903 opt: 1903  Z-score: 1435.3  bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)

         20        30        40        50        60        70      
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
                                     ::::::::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

         80        90       100       110       120       130      
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
              100       110       120       130       140       150

        200       210       220       230       240       250      
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
              160       170       180       190       200       210

        260       270       280       290       300       310      
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
              220       230       240       250       260       270

        320       330       
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
       :::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
              280       290 

>>XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 1903 init1: 1903 opt: 1903  Z-score: 1435.3  bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)

         20        30        40        50        60        70      
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
                                     ::::::::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

         80        90       100       110       120       130      
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
              100       110       120       130       140       150

        200       210       220       230       240       250      
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
              160       170       180       190       200       210

        260       270       280       290       300       310      
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
              220       230       240       250       260       270

        320       330       
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
       :::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
              280       290 

>>XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhancer-  (291 aa)
 initn: 1903 init1: 1903 opt: 1903  Z-score: 1435.3  bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)

         20        30        40        50        60        70      
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
                                     ::::::::::::::::::::::::::::::
XP_016                               MARKKRRGIIEKRRRDRINNSLSELRRLVP
                                             10        20        30

         80        90       100       110       120       130      
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
              100       110       120       130       140       150

        200       210       220       230       240       250      
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
              160       170       180       190       200       210

        260       270       280       290       300       310      
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
              220       230       240       250       260       270

        320       330       
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
       :::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
              280       290 

>>NP_036390 (OMIM: 602953) hairy/enhancer-of-split relat  (304 aa)
 initn: 899 init1: 798 opt: 858  Z-score: 658.1  bits: 130.0 E(85289): 6.5e-30
Smith-Waterman score: 999; 54.7% identity (72.8% similar) in 342 aa overlap (1-337:1-304)

                10        20        30        40        50         
pF1KB7 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
       :::   : ..:.:..::::.: .:.   . . ::..   ::::.:::.:::.::::::::
NP_036 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB7 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
       :::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
NP_036 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
       :. :.::::::.::::::: .::::.::::::::::::.. :.:::::    : ::    
NP_036 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
              130       140       150       160           170      

     180       190          200       210       220       230      
pF1KB7 LHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
         :  :...: : :     :: :.. :.. .:     :.: . : : . : .:   : ..
NP_036 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
          180       190       200            210       220         

         240       250       260       270       280       290     
pF1KB7 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
        ::: : .::..: : :. ::  .::  . ...:. .:    ::.:: :.: .: :::  
NP_036 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSPNA--
        230        240       250       260            270          

         300       310       320       330       
pF1KB7 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
              .::       :.: :...   .:::::::::.:::
NP_036 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
             280              290         300    

>>NP_001035798 (OMIM: 602953) hairy/enhancer-of-split re  (308 aa)
 initn: 589 init1: 488 opt: 840  Z-score: 644.6  bits: 127.5 E(85289): 3.6e-29
Smith-Waterman score: 981; 54.0% identity (72.0% similar) in 346 aa overlap (1-337:1-308)

                10        20        30        40        50         
pF1KB7 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
       :::   : ..:.:..::::.: .:.   . . ::..   ::::.:::.:::.::::::::
NP_001 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
               10        20        30        40        50        60

      60        70        80            90       100       110     
pF1KB7 RRDRINNSLSELRRLVPTAFEKQ----GSAKLEKAEILQMTVDHLKMLQATGGKGYFDAH
       :::::::::::::::::.:::::    :::::::::::::::::::::...:::::::::
NP_001 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB7 ALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAH
       :::::. :.::::::.::::::: .::::.::::::::::::.. :.:::::    : ::
NP_001 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAH
              130       140       150       160       170          

         180       190          200       210       220       230  
pF1KB7 HHHPLHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFA
             :  :...: : :     :: :.. :.. .:     :.: . : : . : .:   
NP_001 AGLGHIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---
        180         190       200       210            220         

             240       250       260       270       280       290 
pF1KB7 HADS-ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPP
       : .. ::: : .::..: : :. ::  .::  . ...:. .:    ::.:: :.: .: :
NP_001 HPEAPALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSP
        230       240        250       260           270        280

             300       310       320       330       
pF1KB7 NAAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
       ::         .::       :.: :...   .:::::::::.:::
NP_001 NA---------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
                              290         300        

>>NP_055386 (OMIM: 609034) hairy/enhancer-of-split relat  (328 aa)
 initn: 725 init1: 552 opt: 752  Z-score: 578.8  bits: 115.4 E(85289): 1.7e-25
Smith-Waterman score: 752; 46.1% identity (65.1% similar) in 347 aa overlap (1-337:1-328)

               10        20        30        40        50        60
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
       :::: : . :... :  ::::.:    :: .. .  :..:.. ::..:::::::::::::
NP_055 MKRPKEPSGSDGESDGPIDVGQE----GQLSQMARPLSTPSS-SQMQARKKRRGIIEKRR
               10        20            30         40        50     

               70        80        90       100       110       120
pF1KB7 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
       :::::.::::::::::::::::::.::::::.:::::::::::.:::: :.:::.:::.:
NP_055 RDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVD
          60        70        80        90       100       110     

              130       140        150       160        170        
pF1KB7 FMSIGFRECLTEVARYLSSVEGLDS-SDPLRVRLVSHLSTCATQREAAAM-TSSMAHHHH
       : ::::::::::: :::. .:: .: .::.:.::.:::.. :.. : .   :. .:    
NP_055 FRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAF---
         120       130       140       150       160       170     

      180       190       200       210       220       230        
pF1KB7 PLHPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSAL
       :  :  :.  ::  :.     : :     .:  .      :     :: :: . .: ...
NP_055 PAWP--WSF-FHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRA-TGI
               180       190       200       210       220         

      240       250          260       270         280       290   
pF1KB7 RMPSTGSVAPCVPPLSTSL---LSLSATVHAAAAAATAA--AHSFPLSFAGAFPMLPPNA
        .:.  .: :     ::     :   ::   .: .. ::  .:  :: . .. :  ::. 
NP_055 ILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPL-LQSSSPT-PPGP
      230       240       250       260       270        280       

           300       310       320       330          
pF1KB7 AAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWG---TEVGAF
       ... :: .:.  : :    :::  ..  ..   :. :    ::.:::
NP_055 TGS-AAYVAVPTPNS----SSPGPAGRPAGAMLYHSWVSEITEIGAF
         290       300           310       320        

>>XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhancer-  (300 aa)
 initn: 653 init1: 545 opt: 683  Z-score: 528.0  bits: 105.9 E(85289): 1.1e-22
Smith-Waterman score: 683; 46.6% identity (65.6% similar) in 311 aa overlap (37-337:5-300)

         10        20        30        40        50        60      
pF1KB7 ETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINN
                                     :..:.. ::..::::.:::::::::::::.
XP_005                           MARPLSTPSS-SQMQARKKHRGIIEKRRRDRINS
                                         10         20        30   

         70        80        90       100       110       120      
pF1KB7 SLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGF
       ::::::::::::::::::.::::::.:::::::::::.:::: :.:::.:::.:: ::::
XP_005 SLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGF
            40        50        60        70        80        90   

        130       140        150       160        170       180    
pF1KB7 RECLTEVARYLSSVEGLDS-SDPLRVRLVSHLSTCATQREAAAM-TSSMAHHHHPLHPHH
       ::::::: :::. .:: .: .::.:.::.:::.. :.. : .   :. .:    :  :  
XP_005 RECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAF---PAWP--
           100       110       120       130       140             

          190       200       210       220       230       240    
pF1KB7 WAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTG
       :.  ::  :.     : :     .:  .      :     :: :: . .: ... .:.  
XP_005 WSF-FHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRA-TGIILPARR
      150        160       170       180       190        200      

          250          260       270         280       290         
pF1KB7 SVAPCVPPLSTSL---LSLSATVHAAAAAATAA--AHSFPLSFAGAFPMLPPNAAAAVAA
       .: :     ::     :   ::   .: .. ::  .:  :: . .. :  ::. ... ::
XP_005 NVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPL-LQSSSPT-PPGPTGS-AA
        210       220       230       240        250        260    

     300       310       320       330          
pF1KB7 ATAISPPLSVSATSSPQQTSSGTNNKPYRPWG---TEVGAF
        .:.  : :    :::  ..  ..   :. :    ::.:::
XP_005 YVAVPTPNS----SSPGPAGRPAGAMLYHSWVSEITEIGAF
           270           280       290       300

>>NP_001269780 (OMIM: 602953) hairy/enhancer-of-split re  (214 aa)
 initn: 445 init1: 344 opt: 400  Z-score: 319.7  bits: 66.9 E(85289): 4.5e-11
Smith-Waterman score: 541; 44.7% identity (64.7% similar) in 255 aa overlap (87-337:3-214)

         60        70        80        90       100       110      
pF1KB7 EKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHA
                                     ::. ... ..  .:     :: .:::::::
NP_001                             MPLEERNVFWLSKGNL-----TGDQGYFDAHA
                                           10             20       

        120       130       140       150       160       170      
pF1KB7 LAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHH
       ::::. :.::::::.::::::: .::::.::::::::::::.. :.:::::    : :: 
NP_001 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHA
        30        40        50        60        70            80   

        180       190          200       210       220       230   
pF1KB7 HHPLHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAH
            :  :...: : :     :: :.. :.. .:     :.: . : : . : .:   :
NP_001 GLGHIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---H
              90       100       110            120       130      

            240       250       260       270       280       290  
pF1KB7 ADS-ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPN
        .. ::: : .::..: : :. ::  .::  . ...:. .:    ::.:: :.: .: ::
NP_001 PEAPALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSPN
           140        150       160       170            180       

            300       310       320       330       
pF1KB7 AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
       :         .::       :.: :...   .:::::::::.:::
NP_001 A---------LSP-------SAPTQAAN--LGKPYRPWGTEIGAF
                190                200       210    

>>NP_005515 (OMIM: 139605) transcription factor HES-1 [H  (280 aa)
 initn: 322 init1: 157 opt: 335  Z-score: 269.7  bits: 58.0 E(85289): 2.8e-08
Smith-Waterman score: 354; 32.3% identity (56.0% similar) in 316 aa overlap (23-330:7-278)

               10        20        30            40        50      
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNS----PTTTSQIMARKKRRGII
                             :.: :.  ...   .:.    : :.:.   ::. . :.
NP_005                 MPADIMEKNSSSPVAATPASVNTTPDKPKTASE--HRKSSKPIM
                               10        20        30          40  

         60        70        80          90       100       110    
pF1KB7 EKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQATGGKGYFDA
       ::::: :::.:::.:. :.  :..:..:  .:::::.::.::: ::. :: .   . ...
NP_005 EKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALST
             50        60        70        80        90       100  

          120       130       140       150       160       170    
pF1KB7 HALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMA
          ..  .  :: ::..::.:.::. ::...   .:.::..::..: ::    :::    
NP_005 DPSVLGKYRAGFSECMNEVTRFLSTCEGVNT--EVRTRLLGHLANCMTQ--INAMT----
            110       120       130         140         150        

          180       190       200        210       220       230   
pF1KB7 HHHHPLHPHHWAAAFHHLPAALLQPNG-LHASESTPCRLSTTSEVPPAHGSALLTATFAH
          .: .::    :..  :     :.:  ::  . :  :     ::   :.:        
NP_005 ---YPGQPH---PALQAPPPPPPGPGGPQHAPFAPPPPL-----VPIPGGAA--------
             160          170       180            190             

           240       250       260       270       280        290  
pF1KB7 ADSALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFA-GAFPMLPPN
              :  :. :::   :. :  . .: : ..  .. :   .: . .  :::    : 
NP_005 -------PPPGG-APC--KLG-SQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPV
                200           210       220       230       240    

            300       310       320       330       
pF1KB7 AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
         . .. . .   : .:: .:.:    : : .. .:::       
NP_005 IPVYTSNSGTSVGPNAVSPSSGP----SLTADSMWRPWRN     
          250       260           270       280     




337 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 21:29:36 2016 done: Fri Nov  4 21:29:38 2016
 Total Scan time:  9.220 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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