Result of FASTA (ccds) for pF1KB7327
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7327, 838 aa
  1>>>pF1KB7327 838 - 838 aa - 838 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2226+/-0.00131; mu= 6.9603+/- 0.078
 mean_var=177.7592+/-34.994, 0's: 0 Z-trim(105.8): 71  B-trim: 0 in 0/50
 Lambda= 0.096196
 statistics sampled from 8583 (8646) to 8583 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.266), width:  16
 Scan time:  2.960

The best scores are:                                      opt bits E(32554)
CCDS7434.1 HELLS gene_id:3070|Hs108|chr10          ( 838) 5499 776.7       0
CCDS73165.1 HELLS gene_id:3070|Hs108|chr10         ( 714) 4720 668.5 1.1e-191
CCDS73164.1 HELLS gene_id:3070|Hs108|chr10         ( 700) 4593 650.9 2.2e-186
CCDS73162.1 HELLS gene_id:3070|Hs108|chr10         ( 884) 2934 420.7 5.4e-117
CCDS73163.1 HELLS gene_id:3070|Hs108|chr10         ( 740) 2580 371.5 2.9e-102
CCDS76018.1 SMARCA1 gene_id:6594|Hs108|chrX        (1058)  784 122.4 4.1e-27
CCDS3761.1 SMARCA5 gene_id:8467|Hs108|chr4         (1052)  770 120.5 1.6e-26
CCDS34204.1 CHD1 gene_id:1105|Hs108|chr5           (1710)  694 110.0 3.5e-23
CCDS10374.2 CHD2 gene_id:1106|Hs108|chr15          (1828)  694 110.1 3.7e-23
CCDS58914.1 SMARCAD1 gene_id:56916|Hs108|chr4      ( 596)  674 107.0   1e-22
CCDS3639.1 SMARCAD1 gene_id:56916|Hs108|chr4       (1026)  674 107.1 1.6e-22
CCDS47101.1 SMARCAD1 gene_id:56916|Hs108|chr4      (1028)  674 107.1 1.6e-22
CCDS72882.1 CHD1L gene_id:9557|Hs108|chr1          ( 797)  652 104.0 1.1e-21
CCDS927.1 CHD1L gene_id:9557|Hs108|chr1            ( 897)  652 104.0 1.2e-21
CCDS58021.1 CHD1L gene_id:9557|Hs108|chr1          ( 693)  649 103.5 1.3e-21
CCDS58022.1 CHD1L gene_id:9557|Hs108|chr1          ( 616)  648 103.4 1.3e-21
CCDS76510.1 CHD4 gene_id:1108|Hs108|chr12          (1905)  636 102.0   1e-20
CCDS8552.1 CHD4 gene_id:1108|Hs108|chr12           (1912)  636 102.0   1e-20
CCDS57.1 CHD5 gene_id:26038|Hs108|chr1             (1954)  630 101.2 1.8e-20
CCDS32555.1 CHD3 gene_id:1107|Hs108|chr17          (1966)  626 100.7 2.7e-20
CCDS32554.1 CHD3 gene_id:1107|Hs108|chr17          (2000)  626 100.7 2.7e-20
CCDS32553.2 CHD3 gene_id:1107|Hs108|chr17          (2059)  626 100.7 2.8e-20
CCDS83338.1 SMARCA2 gene_id:6595|Hs108|chr9        (1514)  619 99.6 4.3e-20
CCDS34978.1 SMARCA2 gene_id:6595|Hs108|chr9        (1572)  619 99.6 4.4e-20
CCDS34977.1 SMARCA2 gene_id:6595|Hs108|chr9        (1590)  619 99.6 4.5e-20
CCDS54218.1 SMARCA4 gene_id:6597|Hs108|chr19       (1613)  615 99.1 6.6e-20
CCDS54217.1 SMARCA4 gene_id:6597|Hs108|chr19       (1614)  615 99.1 6.6e-20
CCDS45973.1 SMARCA4 gene_id:6597|Hs108|chr19       (1616)  615 99.1 6.6e-20
CCDS45972.1 SMARCA4 gene_id:6597|Hs108|chr19       (1617)  615 99.1 6.6e-20
CCDS12253.1 SMARCA4 gene_id:6597|Hs108|chr19       (1647)  605 97.7 1.8e-19
CCDS10071.1 INO80 gene_id:54617|Hs108|chr15        (1556)  600 97.0 2.7e-19
CCDS13317.1 CHD6 gene_id:84181|Hs108|chr20         (2715)  592 96.0 9.1e-19
CCDS45485.1 CHD9 gene_id:80205|Hs108|chr16         (2881)  591 95.9 1.1e-18
CCDS76865.1 CHD9 gene_id:80205|Hs108|chr16         (2897)  591 95.9 1.1e-18
CCDS45081.1 CHD8 gene_id:57680|Hs108|chr14         (2302)  583 94.7 1.9e-18
CCDS53885.1 CHD8 gene_id:57680|Hs108|chr14         (2581)  583 94.8 2.1e-18
CCDS47865.1 CHD7 gene_id:55636|Hs108|chr8          (2997)  578 94.1 3.8e-18
CCDS10689.2 SRCAP gene_id:10847|Hs108|chr16        (3230)  526 86.9   6e-16
CCDS7229.1 ERCC6 gene_id:2074|Hs108|chr10          (1493)  492 82.0 8.6e-15
CCDS35329.1 ERCC6L gene_id:54821|Hs108|chrX        (1250)  447 75.7 5.6e-13
CCDS14612.1 SMARCA1 gene_id:6594|Hs108|chrX        (1054)  434 73.8 1.7e-12
CCDS76019.1 SMARCA1 gene_id:6594|Hs108|chrX        (1070)  434 73.8 1.7e-12
CCDS35072.1 ERCC6L2 gene_id:375748|Hs108|chr9      ( 712)  427 72.7 2.5e-12
CCDS532.1 RAD54L gene_id:8438|Hs108|chr1           ( 747)  410 70.4 1.3e-11
CCDS75768.1 RAD54B gene_id:25788|Hs108|chr8        ( 726)  391 67.7   8e-11
CCDS7419.1 BTAF1 gene_id:9044|Hs108|chr10          (1849)  397 68.9 9.4e-11
CCDS6262.1 RAD54B gene_id:25788|Hs108|chr8         ( 910)  391 67.8 9.6e-11


>>CCDS7434.1 HELLS gene_id:3070|Hs108|chr10               (838 aa)
 initn: 5499 init1: 5499 opt: 5499  Z-score: 4138.1  bits: 776.7 E(32554):    0
Smith-Waterman score: 5499; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
              790       800       810       820       830        

>>CCDS73165.1 HELLS gene_id:3070|Hs108|chr10              (714 aa)
 initn: 4720 init1: 4720 opt: 4720  Z-score: 3554.8  bits: 668.5 E(32554): 1.1e-191
Smith-Waterman score: 4720; 100.0% identity (100.0% similar) in 714 aa overlap (125-838:1-714)

          100       110       120       130       140       150    
pF1KB7 KKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKN
                                     ::::::::::::::::::::::::::::::
CCDS73                               MRKKRGREDESYNISEVMSKEEILSVAKKN
                                             10        20        30

          160       170       180       190       200       210    
pF1KB7 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ
               40        50        60        70        80        90

          220       230       240       250       260       270    
pF1KB7 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF
              100       110       120       130       140       150

          280       290       300       310       320       330    
pF1KB7 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE
              160       170       180       190       200       210

          340       350       360       370       380       390    
pF1KB7 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW
              220       230       240       250       260       270

          400       410       420       430       440       450    
pF1KB7 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS
              280       290       300       310       320       330

          460       470       480       490       500       510    
pF1KB7 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK
              340       350       360       370       380       390

          520       530       540       550       560       570    
pF1KB7 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP
              400       410       420       430       440       450

          580       590       600       610       620       630    
pF1KB7 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY
              460       470       480       490       500       510

          640       650       660       670       680       690    
pF1KB7 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS
              520       530       540       550       560       570

          700       710       720       730       740       750    
pF1KB7 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG
              580       590       600       610       620       630

          760       770       780       790       800       810    
pF1KB7 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG
              640       650       660       670       680       690

          820       830        
pF1KB7 PIKEKMGIFKILENSEDSSPECLF
       ::::::::::::::::::::::::
CCDS73 PIKEKMGIFKILENSEDSSPECLF
              700       710    

>>CCDS73164.1 HELLS gene_id:3070|Hs108|chr10              (700 aa)
 initn: 4593 init1: 4593 opt: 4593  Z-score: 3459.6  bits: 650.9 E(32554): 2.2e-186
Smith-Waterman score: 4593; 99.3% identity (99.7% similar) in 699 aa overlap (140-838:2-700)

     110       120       130       140       150       160         
pF1KB7 KKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLC
                                     .:  ..::::::::::::::::::::::::
CCDS73                              MQVKRSQEILSVAKKNKKENEDENSSSTNLC
                                            10        20        30 

     170       180       190       200       210       220         
pF1KB7 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE
              40        50        60        70        80        90 

     230       240       250       260       270       280         
pF1KB7 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE
             100       110       120       130       140       150 

     290       300       310       320       330       340         
pF1KB7 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK
             160       170       180       190       200       210 

     350       360       370       380       390       400         
pF1KB7 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK
             220       230       240       250       260       270 

     410       420       430       440       450       460         
pF1KB7 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY
             280       290       300       310       320       330 

     470       480       490       500       510       520         
pF1KB7 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE
             340       350       360       370       380       390 

     530       540       550       560       570       580         
pF1KB7 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK
             400       410       420       430       440       450 

     590       600       610       620       630       640         
pF1KB7 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
             460       470       480       490       500       510 

     650       660       670       680       690       700         
pF1KB7 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH
             520       530       540       550       560       570 

     710       720       730       740       750       760         
pF1KB7 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK
             580       590       600       610       620       630 

     770       780       790       800       810       820         
pF1KB7 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
             640       650       660       670       680       690 

     830        
pF1KB7 EDSSPECLF
       :::::::::
CCDS73 EDSSPECLF
             700

>>CCDS73162.1 HELLS gene_id:3070|Hs108|chr10              (884 aa)
 initn: 2932 init1: 2932 opt: 2934  Z-score: 2213.9  bits: 420.7 E(32554): 5.4e-117
Smith-Waterman score: 5303; 94.7% identity (94.7% similar) in 870 aa overlap (1-824:1-870)

               10        20        30        40        50        60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
              370       380       390       400       410       420

              430       440                                        
pF1KB7 SETAEDIIAKEREQNVLHMLHQ--------------------------------------
       ::::::::::::::::::::::                                      
CCDS73 SETAEDIIAKEREQNVLHMLHQERIPRMYVSEFTDEGFFEGKLPSRKDLYDIRPYENTYL
              430       440       450       460       470       480

                    450       460       470       480       490    
pF1KB7 --------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LKLHTNFEILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS
              490       500       510       520       530       540

          500       510       520       530       540       550    
pF1KB7 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES
              550       560       570       580       590       600

          560       570       580       590       600       610    
pF1KB7 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR
              610       620       630       640       650       660

          620       630       640       650       660       670    
pF1KB7 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST
              670       680       690       700       710       720

          680       690       700       710       720       730    
pF1KB7 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE
              730       740       750       760       770       780

          740       750       760       770       780       790    
pF1KB7 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD
              790       800       810       820       830       840

          800       810       820       830        
pF1KB7 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
       ::::::::::::::::::::::::::::::              
CCDS73 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
              850       860       870       880    

>>CCDS73163.1 HELLS gene_id:3070|Hs108|chr10              (740 aa)
 initn: 2576 init1: 2576 opt: 2580  Z-score: 1949.5  bits: 371.5 E(32554): 2.9e-102
Smith-Waterman score: 4630; 88.3% identity (88.3% similar) in 838 aa overlap (1-838:1-740)

               10        20        30        40        50        60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
       ::::::::::::::::::::::::::::::::::::::::::::                
CCDS73 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQ----------------
              310       320       330       340                    

              370       380       390       400       410       420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
                                                                   
CCDS73 ------------------------------------------------------------
                                                                   

              430       440       450       460       470       480
pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
                             ::::::::::::::::::::::::::::::::::::::
CCDS73 ----------------------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
                                350       360       370       380  

              490       500       510       520       530       540
pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
            390       400       410       420       430       440  

              550       560       570       580       590       600
pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
            450       460       470       480       490       500  

              610       620       630       640       650       660
pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
            510       520       530       540       550       560  

              670       680       690       700       710       720
pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
            570       580       590       600       610       620  

              730       740       750       760       770       780
pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
            630       640       650       660       670       680  

              790       800       810       820       830        
pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
            690       700       710       720       730       740

>>CCDS76018.1 SMARCA1 gene_id:6594|Hs108|chrX             (1058 aa)
 initn: 1597 init1: 389 opt: 784  Z-score: 600.2  bits: 122.4 E(32554): 4.1e-27
Smith-Waterman score: 1526; 37.4% identity (66.2% similar) in 727 aa overlap (92-805:45-685)

              70        80        90       100           110       
pF1KB7 EIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKE----SLKVKKGKNSID
                                     :     :: :.:::    :...: . ..  
CCDS76 ADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKNVSSFQLKLAAKAPK
           20        30        40        50        60        70    

       120       130       140       150       160       170       
pF1KB7 ASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNK
       . .:     ... . :..  .  .... :..  :.  .   .   .:  :. .   . .:
CCDS76 SEKEMDPEYEEKMKADRAKRFEFLLKQTELF--AHFIQPSAQKSPTSPLNMKLGRPRIKK
           80        90       100         110       120       130  

        180          190       200       210        220       230  
pF1KB7 D-SNSIIKD---RLSETVRQNTKFFFDPVRKCNGQPVPFQ-QPKHFTGGVMRWYQVEGME
       : ..:.:.    :  .: ... . ...  :: ..  . :. .:..  :: .: ::..:..
CCDS76 DEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKGGPLRDYQIRGLN
            140       150       160       170       180       190  

            240       250       260        270       280       290 
pF1KB7 WLRMLWENGINGILADEMGLGKTVQCIATIALMIQ-RGVPGPFLVCGPLSTLPNWMAEFK
       ::  :.:::.:::::::::::::.: :: .. . . :..::: .:  : ::: ::: :::
CCDS76 WLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFK
            200       210       220       230       240       250  

             300       310       320       330       340       350 
pF1KB7 RFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYL
       :..:.. .. . : .. :  ..:. .   :  .   : .::.:........... .:.::
CCDS76 RWVPSLRVICFVGDKDARAAFIRDEMM-PGEWD---VCVTSYEMVIKEKSVFKKFHWRYL
            260       270        280          290       300        

             360       370       380       390       400       410 
pF1KB7 IVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSF
       ..::.::::: : .: . ...:.. :.:::::::::::: :::.::::::::::..  .:
CCDS76 VIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDF
      310       320       330       340       350       360        

             420       430       440       450       460       470 
pF1KB7 ESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAP
       .::::       ... ..   .:.... :: .: ::::::.:.::   .:::.:. .:  
CCDS76 DSWFD-------TKNCLG---DQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLG
      370                 380       390       400       410        

             480       490       500       510       520       530 
pF1KB7 LSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKL
       ::: :. .:: :. . : ....::                       .:.:         
CCDS76 LSKMQREWYTKILMKDI-DVLNSS-----------------------GKMD---------
      420       430        440                                     

             540       550       560       570         580         
pF1KB7 ISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIE--YPIDPVTQEFK
                                ...: ::.: ::::::::::..   :  : :    
CCDS76 -------------------------KMRLLNILMQLRKCCNHPYLFDGAEPGPPYTT---
                                  450       460       470          

     590       600       610       620       630       640         
pF1KB7 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
        ::..:.::::...::..: .::..: .::.::::: .:::: :::  : ... ::::. 
CCDS76 -DEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQT
        480       490       500       510       520       530      

     650       660        670       680       690       700        
pF1KB7 SYSEREKNMHSFNT-DPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRC
        . :::. ...::. .   :::..:::::::::::..::.::.:::::::: ::::.:: 
CCDS76 PHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRA
        540       550       560       570       580       590      

      710       720       730       740       750       760        
pF1KB7 HRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDP
       ::::: ::: :.::.: ::....:::::  : .:....:.....   ::      : :  
CCDS76 HRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQS------NKLAK
        600       610       620       630       640             650

      770       780       790       800       810       820        
pF1KB7 KELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILEN
       .:.....  :    .. .:.:. ..:.:.  .:.:..                       
CCDS76 EEMLQMI--RHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
                660       670       680       690       700        

      830                                                          
pF1KB7 SEDSSPECLF                                                  
                                                                   
CCDS76 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
      710       720       730       740       750       760        

>>CCDS3761.1 SMARCA5 gene_id:8467|Hs108|chr4              (1052 aa)
 initn: 1552 init1: 372 opt: 770  Z-score: 589.7  bits: 120.5 E(32554): 1.6e-26
Smith-Waterman score: 1489; 36.5% identity (62.2% similar) in 802 aa overlap (7-803:32-680)

                                       10        20        30      
pF1KB7                         MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQ
                                     ...:: :. :     ..:   ::  : :: 
CCDS37 SSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEI
              10        20        30        40        50        60 

         40        50        60        70        80        90      
pF1KB7 LEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKK
       .. :.  ..... :      .. .:. :  :...::........:.       :   :: 
CCDS37 FDDASPGKQKEIQEPDPTYEEKMQTD-RANRFEYLLKQTELFAHFI-------QPAAQKT
              70        80         90       100              110   

        100       110       120       130       140       150      
pF1KB7 KEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKK
         .       ::.: :.  :  .:.. ..  . :  :  .  .:    ::.:.       
CCDS37 PTS------PLKMKPGRPRIKKDEKQNLL--SVG--DYRHRRTEQEEDEELLT-------
                 120       130           140       150             

        160       170       180       190       200       210      
pF1KB7 ENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPK
           :.:..::.:.    . .:: : .:                                
CCDS37 ----ESSKATNVCT----RFEDSPSYVK--------------------------------
            160           170                                      

        220       230       240       250       260        270     
pF1KB7 HFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQ-RGVPGPFL
           : .: :::.:..::  :.:::::::::::::::::.: :. .. : . :..::: .
CCDS37 ---WGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHM
           180       190       200       210       220       230   

         280       290       300       310       320       330     
pF1KB7 VCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEI
       :  : ::: :::.::::..: . ..   : .:.:  .::..    :  .   : .::.:.
CCDS37 VLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLL-PGEWD---VCVTSYEM
           240       250       260       270        280            

         340       350       360       370       380       390     
pF1KB7 AMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWS
        .........  :.::..::.::::: : .: . ...:.. :.:::::::::::: ::::
CCDS37 LIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWS
     290       300       310       320       330       340         

         400       410       420       430       440       450     
pF1KB7 LLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSD
       ::::::::::..  .:.::::       ... ..   .:.... ::..: ::::::.:.:
CCDS37 LLNFLLPDVFNSADDFDSWFD-------TNNCLG---DQKLVERLHMVLRPFLLRRIKAD
     350       360       370                 380       390         

         460       470       480       490       500       510     
pF1KB7 VALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKS
       :   .:::.:: .:. ::: :. .:: :. . : ....:.                    
CCDS37 VEKSLPPKKEVKIYVGLSKMQREWYTRILMKDI-DILNSA--------------------
     400       410       420       430                             

         520       530       540       550       560       570     
pF1KB7 INYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPY
          .:.:                                  ...: ::.: :::::::::
CCDS37 ---GKMD----------------------------------KMRLLNILMQLRKCCNHPY
         440                                         450       460 

           580       590       600       610       620       630   
pF1KB7 LIE--YPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMD
       :..   :  : :     : .:::::::...::..::.::..: .::.::::: .:::: :
CCDS37 LFDGAEPGPPYTT----DMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILED
             470           480       490       500       510       

           640       650       660         670       680       690 
pF1KB7 YCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEV--FIFLVSTRAGGLGINLTAADTVII
       ::  :.... ::::.  ..::. .....: .:.   :.:..:::::::::::..::.::.
CCDS37 YCMWRNYEYCRLDGQTPHDERQDSINAYN-EPNSTKFVFMLSTRAGGLGINLATADVVIL
       520       530       540        550       560       570      

             700       710       720       730       740       750 
pF1KB7 YDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNH
       :::::::: ::::.:: ::::::: : :.:..: ::....:::::  : .:....:..  
CCDS37 YDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQ--
        580       590       600       610       620       630      

             760       770       780       790       800       810 
pF1KB7 FKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMN
         :     ::.:  .   :.....  :    .. .:.:. :.:.:.. .:.:        
CCDS37 --GRLVDQNLNK--IGKDEMLQMI--RHGATHVFASKESEITDEDIDGILERGAKKTAEM
            640         650         660       670       680        

             820       830                                         
pF1KB7 ASGPIKEKMGIFKILENSEDSSPECLF                                 
                                                                   
CCDS37 NEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYF
      690       700       710       720       730       740        

>>CCDS34204.1 CHD1 gene_id:1105|Hs108|chr5                (1710 aa)
 initn: 1149 init1: 329 opt: 694  Z-score: 529.7  bits: 110.0 E(32554): 3.5e-23
Smith-Waterman score: 1150; 32.3% identity (59.1% similar) in 792 aa overlap (57-825:310-1021)

         30        40        50        60        70        80      
pF1KB7 TPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTK-
                                     ..:  ::.:  : .    :.:.. .   . 
CCDS34 CRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQY--LIKWKGWSHIHNTWETEET
     280       290       300       310         320       330       

          90       100       110       120       130       140     
pF1KB7 MEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISE-VMSK
       ..::... .:: .. ..: .  :    . : .  :    ...      ..:.: : ....
CCDS34 LKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAH
       340       350       360       370       380       390       

          150       160       170        180       190       200   
pF1KB7 EEILSVAKKNKKENEDENSSSTNLCVED-LQKNKDSNSIIKDRLSETVRQNTKFFFDPVR
        .  :.:       . ..   ..   ::    .:  .. : . .:..  ..: :    : 
CCDS34 SNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVL
       400       410       420       430       440       450       

           210       220           230       240       250         
pF1KB7 KCNGQPVPFQQPKHFTGG----VMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCI
       :   . : ...   . ::     .: ::..:..::   : .: . :::::::::::.: :
CCDS34 KQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTI
       460       470       480       490       500       510       

     260        270       280       290       300       310        
pF1KB7 ATIALMI-QRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYK
       . .  .. .. . ::::.  ::::: .:. :.. .. .. ...: :  . :. .  . . 
CCDS34 SFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWT
       520       530       540       550       560       570       

      320        330       340       350       360       370       
pF1KB7 RKGTLQIH-PVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADN
       .. : ...  ...:..:: ..:.  :    : .. :::.::.::    : . :  :....
CCDS34 HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNH
       580       590       600       610       620       630       

       380       390       400       410       420       430       
pF1KB7 KLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVL
       .::.:::::::.:.::::::.:..:.      .: :: :.       :.  .: :: .  
CCDS34 RLLITGTPLQNSLKELWSLLHFIMPE------KFSSWEDF-------EEEHGKGREYGYA
       640       650       660             670              680    

       440       450       460       470       480       490       
pF1KB7 HMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEK
         ::. : ::::::.:.::   .: : : ..   .:  :. .:  :..:.   .  .:. 
CCDS34 S-LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKG
           690       700       710       720       730       740   

       500       510       520       530       540       550       
pF1KB7 ETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVN
        :     .:                                                   
CCDS34 ST-----SG---------------------------------------------------
                                                                   

       560       570       580       590           600       610   
pF1KB7 LKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEE----LVTNSGKFLILDRMLPELKK
         . :::: :.::::: :::. :  : ..::   .:    :. .:::...::..: .:..
CCDS34 --FLNIMMELKKCCNHCYLIK-P--PDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRE
         750       760          770       780       790       800  

           620       630       640       650       660        670  
pF1KB7 RGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTD-PEVFIFLV
       ::..::.::::. ::::: .: . :.: :.:::::..   :.. .  ::..  : : ::.
CCDS34 RGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLL
            810       820       830       840       850       860  

            680       690       700       710       720       730  
pF1KB7 STRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKI
       :::::::::::..::::.:.:::::::.::::: : ::::: : : .::::: ..... :
CCDS34 STRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDI
            870       880       890       900       910       920  

            740       750          760        770         780      
pF1KB7 VERAAAKRKLEKLIIHKNHFKGG---QSGLNLSKNF-LDPKELMELLK--SRDYEREIKG
       .:::  :  :..:.:..    :    ..:   :..  .. .::  .::  ...  .: .:
CCDS34 LERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEG
            930       940       950       960       970       980  

        790       800       810          820       830             
pF1KB7 SREKVISDKDLELLLDRSDLIDQMNASGPIK---EKMGIFKILENSEDSSPECLF     
        .:.  .. :.. .: :..   . :  ::.    : .. ::.                  
CCDS34 -EEQEPQEMDIDEILKRAET--HENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERN
             990      1000        1010      1020      1030         

CCDS34 SKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSD
    1040      1050      1060      1070      1080      1090         

>>CCDS10374.2 CHD2 gene_id:1106|Hs108|chr15               (1828 aa)
 initn: 1084 init1: 337 opt: 694  Z-score: 529.3  bits: 110.1 E(32554): 3.7e-23
Smith-Waterman score: 1228; 32.9% identity (61.2% similar) in 806 aa overlap (56-825:296-1023)

          30        40        50        60        70        80     
pF1KB7 ITPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTK
                                     .: :. : . . : .    : :.: .   .
CCDS10 VLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEE
         270       280       290       300       310       320     

           90       100       110       120       130       140    
pF1KB7 -MEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISE-VMS
        ..::...  :: :....:.. .:   :: : .  :    ...  .. ...:.: : :..
CCDS10 SLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIA
         330       340       350       360       370       380     

           150       160               170       180       190     
pF1KB7 KEEILSVAKKNKKENEDENSSSTN----LC----VEDLQKNKDSNSIIKDRLSETV----
        .   :.  ..    .... . .:    ::    .   . . .....:  .... .    
CCDS10 VKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFH
         390       400       410       420       430       440     

              200            210       220          230       240  
pF1KB7 -RQNTKFFFDPVRKCNG---QP--VPFQQPKHFTGGV---MRWYQVEGMEWLRMLWENGI
        :.:.: .  :.:.:..   .:  : ...   . ::    .: ::.::..::   : .. 
CCDS10 SRNNSKTI--PTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNN
         450         460       470       480       490       500   

            250       260        270       280       290       300 
pF1KB7 NGILADEMGLGKTVQCIATIALMI-QRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTML
       . :::::::::::.: :. .. .. :. . ::::.  ::::: .:. ::. ..:.: ...
CCDS10 SVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVV
           510       520       530       540       550       560   

             310          320       330       340       350        
pF1KB7 YHGTQEERQKLVRN---IYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHR
       : :    :.  .:.   :...   :... ..::..:: ..:...:    : .: :::.::
CCDS10 YIGDLMSRNT-IREYEWIHSQTKRLKFN-ALITTYEILLKDKTVLGSINWAFLGVDEAHR
           570        580       590        600       610       620 

      360       370       380       390       400       410        
pF1KB7 IKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDIT
       .::    : . :  :.....::.:::::::.:.::::::.:..:.      .:: : :. 
CCDS10 LKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPE------KFEFWEDF-
             630       640       650       660             670     

      420       430       440       450       460       470        
pF1KB7 SLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEI
             :.  .: :: :  . ::..: ::::::.:.::   .: : : .. . .:  :. 
CCDS10 ------EEDHGKGRE-NGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQ
                680        690       700       710       720       

      480       490       500       510       520       530        
pF1KB7 FYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPE
       .:  :..:.   .                  . :: : .                     
CCDS10 YYKWILTRNYKAL-----------------AKGTRGSTS---------------------
       730       740                                               

      540       550       560       570       580        590       
pF1KB7 VDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK-IDEELVTN
                            . ::.: :.::::: :::. : .   .. . :   :. .
CCDS10 --------------------GFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRS
                         750       760       770       780         

       600       610       620       630       640       650       
pF1KB7 SGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKN
       :::...::..: .:..::..::.::::. ::::: .:  .. . :.:::::..   :.. 
CCDS10 SGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQA
     790       800       810       820       830       840         

       660        670       680       690       700       710      
pF1KB7 MHSFNTD-PEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKP
       .  ::.:  : : ::.:::::::::::..::::.:.:::::::.::::: : ::::: : 
CCDS10 LDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQ
     850       860       870       880       890       900         

        720       730       740       750            760       770 
pF1KB7 VVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG-----GQSGLNLSKNFLDPKEL
       : .::::: .:....:.:::  :  :..:.:..    :     ..:: . :. : . .::
CCDS10 VNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPF-NKEEL
     910       920       930       940       950       960         

               780       790       800       810       820         
pF1KB7 MELLK--SRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
         .::  ..:  .:..: .:.  .. :.. .:  ..  ..  ...   : .. ::.    
CCDS10 TAILKFGAEDLFKELEG-EESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFA
      970       980        990      1000      1010      1020       

     830                                                           
pF1KB7 EDSSPECLF                                                   
                                                                   
CCDS10 TMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDS
      1030      1040      1050      1060      1070      1080       

>>CCDS58914.1 SMARCAD1 gene_id:56916|Hs108|chr4           (596 aa)
 initn: 1134 init1: 506 opt: 674  Z-score: 521.2  bits: 107.0 E(32554): 1e-22
Smith-Waterman score: 1137; 37.5% identity (66.5% similar) in 547 aa overlap (206-744:49-569)

         180       190       200       210       220        230    
pF1KB7 NKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGV-MRWYQVEGMEWL
                                     ::    ..::. .. .. .. ::  :..::
CCDS58 IQERDVVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWL
       20        30        40        50        60        70        

          240       250       260       270       280       290    
pF1KB7 RMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFT
        .. ..:.:::::::::::::.: :: .: . :.:  :: :.  : ::. ::. : . . 
CCDS58 ALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVPASTIDNWLREVNLWC
       80        90       100       110       120       130        

          300       310       320       330          340       350 
pF1KB7 PDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMR---DRNALQHCYWKYL
       : . .. :.:.::::...  ::..:    . . :..:... :.    ::. ...   .: 
CCDS58 PTLKVLCYYGSQEERKQIRFNIHSR---YEDYNVIVTTYNCAISSSDDRSLFRRLKLNYA
      140       150       160          170       180       190     

             360       370       380       390       400       410 
pF1KB7 IVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKS-
       : :::: .:::     ..:  .::.:.:::::::.:::: :: :::::..: .:..  : 
CCDS58 IFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSE
         200       210       220       230       240       250     

              420       430       440       450       460       470
pF1KB7 FESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYA
       ..  :.  . :   ..:  :::   . :  .::. ::.:::.: .:  ..:::.. .   
CCDS58 IRRMFSSKTKSADEQSIYEKER---IAHA-KQIIKPFILRRVKEEVLKQLPPKKDRIELC
         260       270          280        290       300       310 

              480          490       500       510       520       
pF1KB7 PLSKKQEIFYTAIVNR---TIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNE
        .:.::: .: .. ::   .: :.  ..:  .. .        . ::  :.  .      
CCDS58 AMSEKQEQLYLGLFNRLKKSINNLEKNTEMCNVMM--------QLRKMANHPLLHRQYYT
             320       330       340               350       360   

       530       540       550       560       570       580       
pF1KB7 LEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQE
        ::: ....  . .: .  :.:  .  : ...... . :   : .. ..         ..
CCDS58 AEKL-KEMSQLMLKEPTHCEANPDLIFE-DMEVMTDFELHVLCKQYRHI---------NN
            370       380       390        400       410           

       590       600       610       620       630       640       
pF1KB7 FKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDG
       :..: .:. .:::: .:  .: :::..: .:.::::.: :::::    . ..  . ::::
CCDS58 FQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDG
            420       430       440       450       460       470  

       650       660       670       680       690       700       
pF1KB7 SMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDR
       . . ::: . .  :::: ..:.::.::.:::::::::.:..::..: : :: .: ::.::
CCDS58 KTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDR
            480       490       500       510       520       530  

       710       720       730       740       750       760       
pF1KB7 CHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLD
       :::.:::: :.: .:.. .::......    : :::.                       
CCDS58 CHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKT
            540       550       560       570       580       590  

       770       780       790       800       810       820       
pF1KB7 PKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILE
                                                                   
CCDS58 SMGL                                                        
                                                                   




838 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 08:41:45 2016 done: Sat Nov  5 08:41:45 2016
 Total Scan time:  2.960 Total Display time:  0.240

Function used was FASTA [36.3.4 Apr, 2011]
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