Result of FASTA (ccds) for pF1KE0502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0502, 211 aa
  1>>>pF1KE0502 211 - 211 aa - 211 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2150+/-0.000662; mu= 13.5673+/- 0.040
 mean_var=57.3171+/-11.571, 0's: 0 Z-trim(109.1): 17  B-trim: 0 in 0/51
 Lambda= 0.169407
 statistics sampled from 10663 (10680) to 10663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.328), width:  16
 Scan time:  1.900

The best scores are:                                      opt bits E(32554)
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22        ( 211) 1479 369.2  1e-102
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22        ( 252)  855 216.7 9.8e-57
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22        ( 205)  840 213.0   1e-55
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17        ( 215)  580 149.5 1.5e-36
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22        ( 196)  508 131.9 2.7e-31
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2          ( 197)  494 128.5 2.9e-30
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3           ( 178)  416 109.4 1.4e-24
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2           ( 174)  400 105.5 2.1e-23
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2           ( 175)  386 102.1 2.3e-22
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2          ( 174)  382 101.1 4.5e-22
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2           ( 174)  361 95.9 1.6e-20
CCDS5926.1 CRYGN gene_id:155051|Hs108|chr7         ( 182)  305 82.3 2.2e-16
CCDS78289.1 CRYGN gene_id:155051|Hs108|chr7        ( 125)  251 69.0 1.5e-12


>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22             (211 aa)
 initn: 1479 init1: 1479 opt: 1479  Z-score: 1957.5  bits: 369.2 E(32554): 1e-102
Smith-Waterman score: 1479; 99.5% identity (99.5% similar) in 211 aa overlap (1-211:1-211)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
              130       140       150       160       170       180

              190       200       210 
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
       :::::::::::::::::::::::::::::::
CCDS13 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
              190       200       210 

>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22             (252 aa)
 initn: 855 init1: 855 opt: 855  Z-score: 1132.0  bits: 216.7 E(32554): 9.8e-57
Smith-Waterman score: 855; 56.9% identity (85.6% similar) in 188 aa overlap (22-209:57-244)

                        10        20        30        40        50 
pF1KE0          MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDS
                                     :.:.....:::::::.: :.:.:: .:.: 
CCDS13 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
         30        40        50        60        70        80      

              60        70        80        90       100       110 
pF1KE0 LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS
        ...: :: : .:::.:::.  ::::.:.::::.::::..::.:  :: :.:.::...:.
CCDS13 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDA
         90       100       110       120       130       140      

             120       130       140       150       160       170 
pF1KE0 PDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQY
        .::. :::.  :.:  .::  ::.::::..::.:::.::.. .::::::..::::: ::
CCDS13 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
        150       160       170       180       190       200      

             180       190       200       210       
pF1KE0 VFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS      
       ..: :..:::::: : :::.::.::.::..:: .: ::        
CCDS13 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
        210       220       230       240       250  

>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22             (205 aa)
 initn: 937 init1: 807 opt: 840  Z-score: 1113.6  bits: 213.0 E(32554): 1e-55
Smith-Waterman score: 840; 53.8% identity (83.0% similar) in 212 aa overlap (1-211:1-205)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
       :: .:    :. ::: ..    . :.:..: :::::.  ::.. ::.: .. .::.::. 
CCDS13 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
                   10           20        30        40        50   

               70        80        90       100       110       120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
       :..:::...:.   .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
CCDS13 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
            60        70        80        90       100       110   

              130       140       150       160       170       180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
       :: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:. 
CCDS13 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
           120       130       140       150       160       170   

              190       200        210 
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
        ... : .::.::::::::..::.:: : ::.
CCDS13 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
           180       190       200     

>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17             (215 aa)
 initn: 572 init1: 307 opt: 580  Z-score: 769.9  bits: 149.5 E(32554): 1.5e-36
Smith-Waterman score: 598; 43.5% identity (74.0% similar) in 200 aa overlap (9-198:17-214)

                       10        20        30        40        50  
pF1KE0         MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSL
                       ..: .. . :.::  .:. .:. ::::::: :... ::....  
CCDS11 METQAEQQELETLPTTKMAQTNPTPGSLG-PWKITIYDQENFQGKRMEFTSSCPNVSERS
               10        20         30        40        50         

             60        70        80        90         100          
pF1KE0 LEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS--NSRDSDSLLSLRPL-NI
       ...: :..:::: :...:  .: :.::.::.:.::::::::  :.   . :.:.::. . 
CCDS11 FDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSA
      60        70        80        90       100       110         

     110       120       130       140        150       160        
pF1KE0 DSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHG-FQDRVASVRAINGTWVGYEFPGYRG
       .  . :. .::.  : ::. :: .:: ::: : : :...:.:..  .:.:: :..:::::
CCDS11 NHKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRG
     120       130       140        150       160       170        

      170           180         190       200       210 
pF1KE0 RQYVFE----RGEYRHWNEWD--ASQPQLQSVRRIRDQKWHKRGRFPSS
        ::..:     :.:.:: ::   :.  :.::.:::.             
CCDS11 YQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ            
      180       190       200       210                 

>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22             (196 aa)
 initn: 447 init1: 250 opt: 508  Z-score: 675.4  bits: 131.9 E(32554): 2.7e-31
Smith-Waterman score: 526; 42.2% identity (72.2% similar) in 187 aa overlap (22-198:10-195)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
                            : .:..... ..:::.: :..:::::. .  .: : :..
CCDS13             MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLK
                           10        20        30        40        

               70        80        90         100        110       
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAW--SNSRDSDSLLSLRPLN-IDSPDHKLH
       : :: :..::  .:.:.:..::.:.:: ::::  ...  .. : :.::    .  : .: 
CCDS13 VLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLT
       50        60        70        80        90       100        

       120       130       140        150       160       170      
pF1KE0 LFENPAFSGRKMEIVDDDVPSLWAHGFQ-DRVASVRAINGTWVGYEFPGYRGRQYVFE--
       .::.  : :.: :. .:: ::: : :.. ..:.: .. .:.::  .:::::: :::.:  
CCDS13 IFEQENFLGKKGEL-SDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECD
      110       120        130       140       150       160       

            180         190       200       210 
pF1KE0 --RGEYRHWNEWDASQP--QLQSVRRIRDQKWHKRGRFPSS
          :.:.:. :: .  :  :.::.:::.             
CCDS13 HHSGDYKHFREWGSHAPTFQVQSIRRIQQ            
       170       180       190                  

>>CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2               (197 aa)
 initn: 469 init1: 211 opt: 494  Z-score: 656.9  bits: 128.5 E(32554): 2.9e-30
Smith-Waterman score: 521; 45.6% identity (75.8% similar) in 182 aa overlap (28-198:16-196)

               10        20        30        40        50          
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTD-SLLEKVGSI
                                  :.. :.:::.::.: ..: .. . . : .: :.
CCDS24             MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSV
                           10        20        30        40        

      60        70        80        90         100        110      
pF1KE0 QVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS--NSRDSDSLLSLRP-LNIDSPDHKL
       .::.: :.:::   :.:.::.:::::::::.:::  .:..:..:::.:: :  .  : ..
CCDS24 KVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRV
       50        60        70        80        90       100        

        120       130       140        150       160       170     
pF1KE0 HLFENPAFSGRKMEIVDDDVPSLWAHGFQDR-VASVRAINGTWVGYEFPGYRGRQYVFER
        :::.  :.: :...:::  ::: . :. .. :.:... .:.::.:..::::: :::.::
CCDS24 TLFEGDNFQGCKFDLVDD-YPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER
      110       120        130       140       150       160       

             180         190       200       210 
pF1KE0 ----GEYRHWNEW--DASQPQLQSVRRIRDQKWHKRGRFPSS
           ::.  ..:   .:   ::::.::..             
CCDS24 DRHSGEFCTYGELGTQAHTGQLQSIRRVQH            
       170       180       190                   

>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3                (178 aa)
 initn: 354 init1: 203 opt: 416  Z-score: 554.6  bits: 109.4 E(32554): 1.4e-24
Smith-Waterman score: 416; 35.6% identity (70.7% similar) in 174 aa overlap (25-197:7-176)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
                               :. .:: .::::.: . . .: ..  . : . .::.
CCDS32                   MSKTGTKITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIK
                                 10        20        30         40 

               70        80        90       100       110          
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSP-DHKLHLF
       ::.: : ..:   : : ...: .:.::... : .   .: : : : ... :  ..:...:
CCDS32 VEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIF
              50        60        70          80        90         

     120       130       140       150       160       170         
pF1KE0 ENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYR
       :.  :::. .: . .: ::.  .  . .. : ....:.:. ::.:.::::::.... :::
CCDS32 EKGDFSGQMYE-TTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYR
     100       110        120       130       140       150        

     180       190       200       210 
pF1KE0 HWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
       .  .: :..: .:: :::              
CCDS32 KPIDWGAASPAVQSFRRIVE            
      160       170                    

>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2                (174 aa)
 initn: 347 init1: 168 opt: 400  Z-score: 533.6  bits: 105.5 E(32554): 2.1e-23
Smith-Waterman score: 400; 34.9% identity (68.0% similar) in 175 aa overlap (25-199:3-172)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
                               :. .:: . :::.  : ...::.: .  . . .::.
CCDS23                       MGKITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIR
                                     10        20         30       

               70        80        90       100       110       120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
       :::: :. .:   ..:.:..:..:.:: .. : .  ::     : : ...   :.:.:.:
CCDS23 VESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS---HRLRLYE
        40        50        60        70        80           90    

              130       140       150       160       170       180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
           .:  ::. ..: ::.  .   ... :.....: :: ::.:.::::::...  :::.
CCDS23 REDHKGLMMEL-SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRR
          100        110       120       130       140       150   

              190       200       210 
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
        ..: : . .  :.::. :            
CCDS23 CQDWGAMDAKAGSLRRVVDLY          
           160       170              

>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2                (175 aa)
 initn: 360 init1: 185 opt: 386  Z-score: 515.0  bits: 102.1 E(32554): 2.3e-22
Smith-Waterman score: 386; 32.6% identity (67.4% similar) in 175 aa overlap (25-199:3-173)

               10        20        30        40        50        60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
                               :. .:: . :::.  : ...::.: .  . . .::.
CCDS23                       MGKITFYEDRAFQGRSYECTTDCPNL-QPYFSRCNSIR
                                     10        20         30       

               70        80        90       100       110       120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
       :::: :. .:   ..:.:. :..:.:: .. : .  ::     : : .  :  .......
CCDS23 VESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGLSDSIRSCCLIPPH--SGAYRMKIYD
        40        50        60        70        80          90     

              130       140       150       160       170       180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
          . :.  :..:: . :.  .    .. :. ...:.:. ::.:.::::::... ::::.
CCDS23 RDELRGQMSELTDDCI-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRR
         100       110        120       130       140       150    

              190       200       210 
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
       . .: : . .. :.::. :            
CCDS23 FLDWGAPNAKVGSLRRVMDLY          
          160       170               

>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2               (174 aa)
 initn: 380 init1: 177 opt: 382  Z-score: 509.8  bits: 101.1 E(32554): 4.5e-22
Smith-Waterman score: 382; 36.0% identity (68.0% similar) in 178 aa overlap (25-199:3-172)

               10        20        30         40        50         
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRC-ELSAECPSLTDSLLEKVGSI
                               :. .:: ..::: :: .  ..::.:    . . .::
CCDS33                       MGKITFYEDRDFQG-RCYNCISDCPNLR-VYFSRCNSI
                                     10         20         30      

      60        70        80        90       100       110         
pF1KE0 QVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLF
       .:.:: :. .:   ..:.:. :..: :: .. : .   :::. : : .   : .:::.:.
CCDS33 RVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGL--SDSVQSCRIIPHTS-SHKLRLY
         40        50        60        70          80         90   

     120       130         140       150       160       170       
pF1KE0 ENPAFSGRKMEIVDDD--VPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGE
       :   . :   :..::   :: :.      .. :.....: :: ::.:.::::::... :.
CCDS33 ERDDYRGLMSELTDDCACVPELFR---LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGD
           100       110          120       130       140       150

       180       190       200       210 
pF1KE0 YRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
       ::....: ... .. :.::. :            
CCDS33 YRRYHDWGGADAKVGSLRRVTDLY          
              160       170              




211 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 03:55:33 2016 done: Thu Nov  3 03:55:33 2016
 Total Scan time:  1.900 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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