Result of FASTA (omim) for pF1KB8443
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8443, 586 aa
  1>>>pF1KB8443 586 - 586 aa - 586 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.0427+/-0.000552; mu= -1.9894+/- 0.034
 mean_var=550.0008+/-120.199, 0's: 0 Z-trim(118.6): 1848  B-trim: 0 in 0/57
 Lambda= 0.054688
 statistics sampled from 29337 (31742) to 29337 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.372), width:  16
 Scan time:  9.950

The best scores are:                                      opt bits E(85289)
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 3876 321.6 4.6e-87
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 3876 321.6 4.7e-87
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 2990 251.7 5.1e-66
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 2896 244.2 8.4e-64
XP_011528146 (OMIM: 114480,176807,259500,604373,60 ( 409) 2514 213.9 8.5e-55
XP_011528142 (OMIM: 114480,176807,259500,604373,60 ( 567) 2508 213.6 1.4e-54
NP_001244316 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_011528147 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_016884050 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_006724179 (OMIM: 114480,176807,259500,604373,60 ( 362) 2072 178.9 2.5e-44
XP_006724177 (OMIM: 114480,176807,259500,604373,60 ( 394) 2066 178.5 3.6e-44
XP_011528145 (OMIM: 114480,176807,259500,604373,60 ( 476) 2067 178.7 3.8e-44
XP_011528144 (OMIM: 114480,176807,259500,604373,60 ( 486) 2067 178.7 3.9e-44
XP_011528143 (OMIM: 114480,176807,259500,604373,60 ( 519) 2067 178.8   4e-44
NP_665861 (OMIM: 114480,176807,259500,604373,60926 ( 514) 1528 136.2 2.5e-31
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370)  737 73.6 1.3e-12
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413)  737 73.7 1.4e-12
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476)  731 73.3 2.1e-12
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476)  731 73.3 2.1e-12
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355)  723 72.5 2.7e-12
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357)  723 72.5 2.7e-12
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362)  723 72.5 2.7e-12
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385)  723 72.5 2.8e-12
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366)  716 71.9   4e-12
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372)  707 71.2 6.7e-12
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473)  665 68.1 7.6e-11
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473)  665 68.1 7.6e-11
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473)  665 68.1 7.6e-11
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  660 67.5 8.3e-11
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360)  660 67.5 8.6e-11
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361)  660 67.5 8.6e-11
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426)  660 67.6 9.4e-11
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426)  660 67.6 9.4e-11
XP_016859232 (OMIM: 607077) PREDICTED: serine/thre ( 631)  651 67.2 1.9e-10
XP_016859233 (OMIM: 607077) PREDICTED: serine/thre ( 631)  651 67.2 1.9e-10
XP_016859230 (OMIM: 607077) PREDICTED: serine/thre ( 717)  651 67.2   2e-10
XP_016859231 (OMIM: 607077) PREDICTED: serine/thre ( 717)  651 67.2   2e-10
XP_005264295 (OMIM: 607077) PREDICTED: serine/thre ( 786)  651 67.3 2.1e-10
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326)  641 65.9 2.3e-10
NP_005804 (OMIM: 607077) serine/threonine-protein  ( 890)  651 67.4 2.3e-10
XP_005264294 (OMIM: 607077) PREDICTED: serine/thre ( 890)  651 67.4 2.3e-10
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369)  641 66.0 2.5e-10
XP_016876951 (OMIM: 605435) PREDICTED: serine/thre ( 747)  648 67.0 2.5e-10


>>NP_001005735 (OMIM: 114480,176807,259500,604373,609265  (586 aa)
 initn: 3876 init1: 3876 opt: 3876  Z-score: 1684.0  bits: 321.6 E(85289): 4.6e-87
Smith-Waterman score: 3876; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:1-586)

               10        20        30        40        50        60
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
              490       500       510       520       530       540

              550       560       570       580      
pF1KB8 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
              550       560       570       580      

>>XP_011528141 (OMIM: 114480,176807,259500,604373,609265  (596 aa)
 initn: 3876 init1: 3876 opt: 3876  Z-score: 1683.9  bits: 321.6 E(85289): 4.7e-87
Smith-Waterman score: 3876; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:11-596)

                         10        20        30        40        50
pF1KB8           MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
              370       380       390       400       410       420

              420       430       440       450       460       470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
              430       440       450       460       470       480

              480       490       500       510       520       530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
              490       500       510       520       530       540

              540       550       560       570       580      
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
              550       560       570       580       590      

>>XP_016884049 (OMIM: 114480,176807,259500,604373,609265  (584 aa)
 initn: 3762 init1: 2890 opt: 2990  Z-score: 1306.2  bits: 251.7 E(85289): 5.1e-66
Smith-Waterman score: 3742; 97.8% identity (98.0% similar) in 586 aa overlap (1-586:11-584)

                         10        20        30        40        50
pF1KB8           MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
       :::::::::::::::::::::::::::            .::::::::::::::::::::
XP_016 GHVTQSDLELLLSSDPPASASQSAGIR------------ECVNDNYWFGRDKSCEYCFDE
              130       140                   150       160        

              180       190       200       210       220       230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
      170       180       190       200       210       220        

              240       250       260       270       280       290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
      230       240       250       260       270       280        

              300       310       320       330       340       350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
      290       300       310       320       330       340        

              360       370       380       390       400       410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
      350       360       370       380       390       400        

              420       430       440       450       460       470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
      410       420       430       440       450       460        

              480       490       500       510       520       530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
      470       480       490       500       510       520        

              540       550       560       570       580      
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
      530       540       550       560       570       580    

>>NP_009125 (OMIM: 114480,176807,259500,604373,609265) s  (543 aa)
 initn: 2896 init1: 2896 opt: 2896  Z-score: 1266.4  bits: 244.2 E(85289): 8.4e-64
Smith-Waterman score: 3494; 92.7% identity (92.7% similar) in 586 aa overlap (1-586:1-543)

               10        20        30        40        50        60
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
       :::::::::::::::::::::::::::::::::::::::::::::::             
NP_009 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLE-------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KB8 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
                                     ::::::::::::::::::::::::::::::
NP_009 ------------------------------CVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
                                     110       120       130       

              190       200       210       220       230       240
pF1KB8 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
       140       150       160       170       180       190       

              250       260       270       280       290       300
pF1KB8 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
       200       210       220       230       240       250       

              310       320       330       340       350       360
pF1KB8 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
       260       270       280       290       300       310       

              370       380       390       400       410       420
pF1KB8 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
       320       330       340       350       360       370       

              430       440       450       460       470       480
pF1KB8 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
       380       390       400       410       420       430       

              490       500       510       520       530       540
pF1KB8 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
       440       450       460       470       480       490       

              550       560       570       580      
pF1KB8 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       500       510       520       530       540   

>>XP_011528146 (OMIM: 114480,176807,259500,604373,609265  (409 aa)
 initn: 2624 init1: 2511 opt: 2514  Z-score: 1104.8  bits: 213.9 E(85289): 8.5e-55
Smith-Waterman score: 2514; 97.9% identity (99.0% similar) in 389 aa overlap (1-387:11-399)

                         10        20        30        40        50
pF1KB8           MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
              310       320       330       340       350       360

              360       370       380         390       400        
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQY--LHENGIIHRDLKPENVLLSSQEEDCLIK
       :::::::::::::::::::::::::::::.  . :: ..                     
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQFSMILENMVVCITAYGFTQL           
              370       380       390       400                    

      410       420       430       440       450       460        
pF1KB8 ITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYP

>>XP_011528142 (OMIM: 114480,176807,259500,604373,609265  (567 aa)
 initn: 2507 init1: 2507 opt: 2508  Z-score: 1100.8  bits: 213.6 E(85289): 1.4e-54
Smith-Waterman score: 3614; 95.1% identity (95.1% similar) in 586 aa overlap (1-586:11-567)

                         10        20        30        40        50
pF1KB8           MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
       :::::::::::::::::::::::::::::                             ::
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQ-----------------------------IT
              370       380                                    390 

              420       430       440       450       460       470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
             400       410       420       430       440       450 

              480       490       500       510       520       530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
             460       470       480       490       500       510 

              540       550       560       570       580      
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
             520       530       540       550       560       

>>NP_001244316 (OMIM: 114480,176807,259500,604373,609265  (322 aa)
 initn: 2107 init1: 2107 opt: 2107  Z-score: 932.3  bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)

          240       250       260       270       280       290    
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
                                     ::::::::::::::::::::::::::::::
NP_001                               MSKTLGSGACGEVKLAFERKTCKKVAIKII
                                             10        20        30

          300       310       320       330       340       350    
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
               40        50        60        70        80        90

          360       370       380       390       400       410    
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
              100       110       120       130       140       150

          420       430       440       450       460       470    
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
              160       170       180       190       200       210

          480       490       500       510       520       530    
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
              220       230       240       250       260       270

          540       550       560       570       580      
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
              280       290       300       310       320  

>>XP_011528147 (OMIM: 114480,176807,259500,604373,609265  (322 aa)
 initn: 2107 init1: 2107 opt: 2107  Z-score: 932.3  bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)

          240       250       260       270       280       290    
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
                                     ::::::::::::::::::::::::::::::
XP_011                               MSKTLGSGACGEVKLAFERKTCKKVAIKII
                                             10        20        30

          300       310       320       330       340       350    
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
               40        50        60        70        80        90

          360       370       380       390       400       410    
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
              100       110       120       130       140       150

          420       430       440       450       460       470    
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
              160       170       180       190       200       210

          480       490       500       510       520       530    
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
              220       230       240       250       260       270

          540       550       560       570       580      
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
              280       290       300       310       320  

>>XP_016884050 (OMIM: 114480,176807,259500,604373,609265  (322 aa)
 initn: 2107 init1: 2107 opt: 2107  Z-score: 932.3  bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)

          240       250       260       270       280       290    
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
                                     ::::::::::::::::::::::::::::::
XP_016                               MSKTLGSGACGEVKLAFERKTCKKVAIKII
                                             10        20        30

          300       310       320       330       340       350    
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
               40        50        60        70        80        90

          360       370       380       390       400       410    
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
              100       110       120       130       140       150

          420       430       440       450       460       470    
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
              160       170       180       190       200       210

          480       490       500       510       520       530    
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
              220       230       240       250       260       270

          540       550       560       570       580      
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
              280       290       300       310       320  

>>XP_006724179 (OMIM: 114480,176807,259500,604373,609265  (362 aa)
 initn: 2071 init1: 2071 opt: 2072  Z-score: 916.8  bits: 178.9 E(85289): 2.5e-44
Smith-Waterman score: 2072; 98.5% identity (98.8% similar) in 323 aa overlap (265-586:40-362)

          240       250       260        270       280       290   
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTL-GSGACGEVKLAFERKTCKKVAIKI
                                     : . : : ::::::::::::::::::::::
XP_006 EFGADLVFLAVKPLTFYTGEVSLCPLQTGTMERLLYGIGACGEVKLAFERKTCKKVAIKI
      10        20        30        40        50        60         

           300       310       320       330       340       350   
pF1KB8 ISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELF
      70        80        90       100       110       120         

           360       370       380       390       400       410   
pF1KB8 DKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG
     130       140       150       160       170       180         

           420       430       440       450       460       470   
pF1KB8 HSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH
     190       200       210       220       230       240         

           480       490       500       510       520       530   
pF1KB8 RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDED
     250       260       270       280       290       300         

           540       550       560       570       580      
pF1KB8 MKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
     310       320       330       340       350       360  




586 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:59:36 2016 done: Sat Nov  5 21:59:38 2016
 Total Scan time:  9.950 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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