Result of FASTA (omim) for pF1KE0218
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0218, 178 aa
  1>>>pF1KE0218 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7096+/-0.000427; mu= 16.1100+/- 0.026
 mean_var=64.9277+/-13.415, 0's: 0 Z-trim(109.9): 10  B-trim: 0 in 0/53
 Lambda= 0.159169
 statistics sampled from 18193 (18202) to 18193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.213), width:  16
 Scan time:  4.840

The best scores are:                                      opt bits E(85289)
NP_001744 (OMIM: 601047,606721,612526,615343) cave ( 178) 1200 284.3 7.2e-77
NP_001166366 (OMIM: 601047,606721,612526,615343) c ( 147)  989 235.7 2.4e-62
NP_001166368 (OMIM: 601047,606721,612526,615343) c ( 147)  989 235.7 2.4e-62
NP_001166367 (OMIM: 601047,606721,612526,615343) c ( 147)  989 235.7 2.4e-62
NP_203123 (OMIM: 123320,192600,601253,606072,60780 ( 151)  703 170.1 1.4e-42
NP_001225 (OMIM: 123320,192600,601253,606072,60780 ( 151)  703 170.1 1.4e-42
NP_001193676 (OMIM: 601048) caveolin-2 isoform b [ ( 149)  355 90.2 1.6e-18
NP_001224 (OMIM: 601048) caveolin-2 isoform a [Hom ( 162)  355 90.2 1.7e-18
NP_001193677 (OMIM: 601048) caveolin-2 isoform d [ (  79)  197 53.7 8.5e-08


>>NP_001744 (OMIM: 601047,606721,612526,615343) caveolin  (178 aa)
 initn: 1200 init1: 1200 opt: 1200  Z-score: 1501.0  bits: 284.3 E(85289): 7.2e-77
Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)

               10        20        30        40        50        60
pF1KE0 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA
               70        80        90       100       110       120

              130       140       150       160       170        
pF1KE0 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
              130       140       150       160       170        

>>NP_001166366 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 989 init1: 989 opt: 989  Z-score: 1240.3  bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)

              10        20        30        40        50        60 
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
                                     ::::::::::::::::::::::::::::::
NP_001                               MADELSEKQVYDAHTKEIDLVNRDPKHLND
                                             10        20        30

              70        80        90       100       110       120 
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
               40        50        60        70        80        90

             130       140       150       160       170        
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
              100       110       120       130       140       

>>NP_001166368 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 989 init1: 989 opt: 989  Z-score: 1240.3  bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)

              10        20        30        40        50        60 
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
                                     ::::::::::::::::::::::::::::::
NP_001                               MADELSEKQVYDAHTKEIDLVNRDPKHLND
                                             10        20        30

              70        80        90       100       110       120 
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
               40        50        60        70        80        90

             130       140       150       160       170        
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
              100       110       120       130       140       

>>NP_001166367 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 989 init1: 989 opt: 989  Z-score: 1240.3  bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)

              10        20        30        40        50        60 
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
                                     ::::::::::::::::::::::::::::::
NP_001                               MADELSEKQVYDAHTKEIDLVNRDPKHLND
                                             10        20        30

              70        80        90       100       110       120 
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
               40        50        60        70        80        90

             130       140       150       160       170        
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
              100       110       120       130       140       

>>NP_203123 (OMIM: 123320,192600,601253,606072,607801,61  (151 aa)
 initn: 691 init1: 678 opt: 703  Z-score: 885.2  bits: 170.1 E(85289): 1.4e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (32-178:2-151)

              10        20        30           40        50        
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH
                                     ::.:   :  . : : : :::::::::::.
NP_203                              MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN
                                            10        20        30 

       60        70        80        90       100       110        
pF1KE0 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY
       .:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::. 
NP_203 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL
              40        50        60        70        80        90 

      120       130       140       150       160       170        
pF1KE0 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       :: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::.
NP_203 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
             100       110       120       130       140       150 

>>NP_001225 (OMIM: 123320,192600,601253,606072,607801,61  (151 aa)
 initn: 691 init1: 678 opt: 703  Z-score: 885.2  bits: 170.1 E(85289): 1.4e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (32-178:2-151)

              10        20        30           40        50        
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH
                                     ::.:   :  . : : : :::::::::::.
NP_001                              MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN
                                            10        20        30 

       60        70        80        90       100       110        
pF1KE0 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY
       .:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::. 
NP_001 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL
              40        50        60        70        80        90 

      120       130       140       150       160       170        
pF1KE0 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       :: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::.
NP_001 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
             100       110       120       130       140       150 

>>NP_001193676 (OMIM: 601048) caveolin-2 isoform b [Homo  (149 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 453.4  bits: 90.2 E(85289): 1.6e-18
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (53-177:26-149)

             30        40        50        60        70        80  
pF1KE0 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001      MDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                    10        20        30         40        50    

             90       100       110       120       130       140  
pF1KE0 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
           60        70        80        90       100       110    

            150       160       170        
pF1KE0 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
          120       130       140          

>>NP_001224 (OMIM: 601048) caveolin-2 isoform a [Homo sa  (162 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 452.9  bits: 90.2 E(85289): 1.7e-18
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (53-177:39-162)

             30        40        50        60        70        80  
pF1KE0 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
       10        20        30        40         50        60       

             90       100       110       120       130       140  
pF1KE0 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        70        80        90       100       110       120       

            150       160       170        
pF1KE0 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
       130       140       150       160   

>>NP_001193677 (OMIM: 601048) caveolin-2 isoform d [Homo  (79 aa)
 initn: 189 init1: 176 opt: 197  Z-score: 261.0  bits: 53.7 E(85289): 8.5e-08
Smith-Waterman score: 197; 34.6% identity (74.4% similar) in 78 aa overlap (100-177:2-79)

      70        80        90       100       110       120         
pF1KE0 DVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWA
                                     :..:.....::.:.: :: :: :: :::: 
NP_001                              MYKFLTVFLAIPLAFIAGILFATLSCLHIWI
                                            10        20        30 

     130       140       150       160       170        
pF1KE0 VVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
       ..: .:. :. .  .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 LMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
              40        50        60        70          




178 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:49:11 2016 done: Sat Nov  5 01:49:11 2016
 Total Scan time:  4.840 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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