Result of FASTA (omim) for
pF1KE0485
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0485, 199 aa
1>>>pF1KE0485 199 - 199 aa - 199 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8293+/-0.000331; mu= 15.5788+/- 0.021
mean_var=57.2230+/-11.105, 0's: 0 Z-trim(115.1): 35 B-trim: 37 in 1/53
Lambda= 0.169547
statistics sampled from 25224 (25261) to 25224 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.296), width: 16
Scan time: 5.690
The best scores are: opt bits E(85289)
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199) 1423 355.9 2.5e-98
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181) 1232 309.1 2.7e-84
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 1191 299.3 5.2e-81
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317) 820 208.5 9.3e-54
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384) 820 208.5 1.1e-53
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357) 804 204.6 1.5e-52
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457) 802 204.2 2.6e-52
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524) 802 204.2 3e-52
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442) 435 114.4 2.7e-25
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455) 426 112.2 1.3e-24
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190) 417 109.8 2.9e-24
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386) 382 101.4 1.9e-21
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198) 378 100.3 2.2e-21
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202) 378 100.3 2.3e-21
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 355 94.8 1.8e-19
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227) 348 93.0 4e-19
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183) 310 83.6 2.1e-16
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182) 305 82.4 4.9e-16
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200) 305 82.4 5.3e-16
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200) 305 82.4 5.3e-16
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 305 82.4 5.4e-16
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 305 82.4 5.4e-16
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188) 263 72.1 6.2e-13
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145) 258 70.8 1.2e-12
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224) 251 69.2 5.5e-12
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191) 245 67.7 1.3e-11
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236) 246 68.0 1.3e-11
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236) 246 68.0 1.3e-11
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154) 204 57.6 1.2e-08
>>NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme APO (199 aa)
initn: 1423 init1: 1423 opt: 1423 Z-score: 1886.2 bits: 355.9 E(85289): 2.5e-98
Smith-Waterman score: 1423; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
130 140 150 160 170 180
190
pF1KE0 EHSQALSGRLRAILQNQGN
:::::::::::::::::::
NP_663 EHSQALSGRLRAILQNQGN
190
>>NP_001257335 (OMIM: 607109) DNA dC->dU-editing enzyme (181 aa)
initn: 1232 init1: 1232 opt: 1232 Z-score: 1634.3 bits: 309.1 E(85289): 2.7e-84
Smith-Waterman score: 1247; 91.0% identity (91.0% similar) in 199 aa overlap (1-199:1-181)
10 20 30 40 50 60
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
::::::::::: :::::::::::::::::::::::::::::::
NP_001 MEASPASGPRH------------------KTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
10 20 30 40
70 80 90 100 110 120
pF1KE0 NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
110 120 130 140 150 160
190
pF1KE0 EHSQALSGRLRAILQNQGN
:::::::::::::::::::
NP_001 EHSQALSGRLRAILQNQGN
170 180
>>NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme APO (382 aa)
initn: 1195 init1: 1133 opt: 1191 Z-score: 1575.4 bits: 299.3 E(85289): 5.2e-81
Smith-Waterman score: 1191; 88.6% identity (93.3% similar) in 193 aa overlap (10-199:190-382)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYE
:.:::: :: :::: . :..::::::
NP_004 FVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYE
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::::::: : :::: ::: :.::::::::::::::::::::::::::::::::::::::
NP_004 VERLDNGTWVLMDQHMGFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
280 290 300 310 320 330
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
::..:::::: .:::::::::::.:::::::::::::::::::
NP_004 EFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
340 350 360 370 380
>--
initn: 375 init1: 182 opt: 378 Z-score: 500.6 bits: 100.4 E(85289): 3.8e-21
Smith-Waterman score: 378; 37.7% identity (62.3% similar) in 191 aa overlap (9-194:8-189)
10 20 30 40 50
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
: . : : .::.: :: :.::::: .. : : .. : ...
NP_004 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEV-KIKRGRS-NLLWDTGVFRG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QAKNLLCGFYGR-HAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQE
:. : . :::. ::. . :: . ...:::.::.:: . :.... ::.:
NP_004 QVY-----FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPD--CVAKLAEFLSE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 NTHVRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQP
. .: : : :::.: : . :..:: : .:::.:.:: :.:: .::..:: ..: :.:
NP_004 HPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMP
120 130 140 150 160 170
180 190
pF1KE0 WDGLDEHSQALSGRLRAILQNQGN
: .::. : :. ::
NP_004 WYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVL
180 190 200 210 220 230
>>XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (317 aa)
initn: 767 init1: 471 opt: 820 Z-score: 1086.1 bits: 208.5 E(85289): 9.3e-54
Smith-Waterman score: 820; 65.3% identity (77.2% similar) in 193 aa overlap (10-199:127-317)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
:: ::: :: :::: :::.::::::
XP_006 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::. : : : ..:.:::: ::: . . :::::: :::..: .:: : :::: :
XP_006 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::: :: :. :...: :: : ::.::::: . .:.:. : .:::..:::::.
XP_006 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
220 230 240 250 260 270
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
:::::::::::::::::::::::::::: :::::::::::: :
XP_006 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
280 290 300 310
>--
initn: 271 init1: 143 opt: 307 Z-score: 408.0 bits: 83.0 E(85289): 5.5e-16
Smith-Waterman score: 307; 45.3% identity (67.5% similar) in 117 aa overlap (83-194:12-126)
60 70 80 90 100 110
pF1KE0 GFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRA
.: : :.:::.:::::: . :. .. .
XP_006 MRFFHWFSKWRKLHRDQEYEVTWYISWSPCTK--CTRDMAT
10 20 30
120 130 140 150 160
pF1KE0 FLQENTHVRLRIFAARIYDY-DPLYKEALQML---RDAG-AQVSIMTYDEFKHCWDTFVD
:: :. .: : ::.::.: . :: :.:::. : ::. : ..::.::::.:::. ::
XP_006 FLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVY
40 50 60 70 80 90
170 180 190
pF1KE0 HQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
: :.::..: .. : : ::
XP_006 SQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVER
100 110 120 130 140 150
>>NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme APO (384 aa)
initn: 828 init1: 471 opt: 820 Z-score: 1084.9 bits: 208.5 E(85289): 1.1e-53
Smith-Waterman score: 820; 65.3% identity (77.2% similar) in 193 aa overlap (10-199:194-384)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
:: ::: :: :::: :::.::::::
NP_068 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::. : : : ..:.:::: ::: . . :::::: :::..: .:: : :::: :
NP_068 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::: :: :. :...: :: : ::.::::: . .:.:. : .:::..:::::.
NP_068 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
290 300 310 320 330 340
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
:::::::::::::::::::::::::::: :::::::::::: :
NP_068 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
350 360 370 380
>--
initn: 295 init1: 143 opt: 348 Z-score: 460.9 bits: 93.1 E(85289): 6.2e-19
Smith-Waterman score: 348; 38.3% identity (61.7% similar) in 188 aa overlap (18-194:17-193)
10 20 30 40 50
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG--IGRHKT-YLCYEVERLDNGTSVKMDQH--RGFL
:. :: : ..:..: .::::: . . . .: . :: .
NP_068 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEV-KTKGPSRPPLDAKIFRGQV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HNQAKNLLCGFYGRHAELRFLDLVPSL-QLDPAQIYRVTWFISWSPCFSWGCAGEVRAFL
... : : :.::. . .: : :.:::.:::::: . :. .. .::
NP_068 YSELK--------YHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTK--CTRDMATFL
60 70 80 90 100
120 130 140 150 160
pF1KE0 QENTHVRLRIFAARIYDY-DPLYKEALQML---RDAG-AQVSIMTYDEFKHCWDTFVDHQ
:. .: : ::.::.: . :: :.:::. : ::. : ..::.::::.:::. :: :
NP_068 AEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQ
110 120 130 140 150 160
170 180 190
pF1KE0 GCPFQPWDGLDEHSQALSGRLRAILQNQGN
:.::..: .. : : ::
NP_068 RELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMH
170 180 190 200 210 220
>>NP_001257340 (OMIM: 607110) DNA dC->dU-editing enzyme (357 aa)
initn: 866 init1: 804 opt: 804 Z-score: 1064.2 bits: 204.6 E(85289): 1.5e-52
Smith-Waterman score: 960; 75.6% identity (80.3% similar) in 193 aa overlap (10-199:190-357)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYE
:.:::: :: :::: . :..::::::
NP_001 FVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYE
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::::::: : :::: ::: :. :::::::::::::
NP_001 VERLDNGTWVLMDQHMGFLCNE-------------------------LDPAQIYRVTWFI
220 230 240 250
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
260 270 280 290 300 310
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
::..:::::: .:::::::::::.:::::::::::::::::::
NP_001 EFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
320 330 340 350
>--
initn: 375 init1: 182 opt: 378 Z-score: 501.1 bits: 100.4 E(85289): 3.6e-21
Smith-Waterman score: 378; 37.7% identity (62.3% similar) in 191 aa overlap (9-194:8-189)
10 20 30 40 50
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
: . : : .::.: :: :.::::: .. : : .. : ...
NP_001 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEV-KIKRGRS-NLLWDTGVFRG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 QAKNLLCGFYGR-HAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQE
:. : . :::. ::. . :: . ...:::.::.:: . :.... ::.:
NP_001 QVY-----FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPD--CVAKLAEFLSE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 NTHVRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQP
. .: : : :::.: : . :..:: : .:::.:.:: :.:: .::..:: ..: :.:
NP_001 HPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMP
120 130 140 150 160 170
180 190
pF1KE0 WDGLDEHSQALSGRLRAILQNQGN
: .::. : :. ::
NP_001 WYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVL
180 190 200 210 220 230
>>XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (457 aa)
initn: 533 init1: 454 opt: 802 Z-score: 1060.0 bits: 204.2 E(85289): 2.6e-52
Smith-Waterman score: 802; 65.1% identity (77.2% similar) in 189 aa overlap (10-195:127-313)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
:: ::: :: :::: :::.::::::
XP_016 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::. : : : ..:.:::: ::: . . :::::: :::..: .:: : :::: :
XP_016 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::: :: :. :...: :: : ::.::::: . .:.:. : .:::..:::::.
XP_016 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
220 230 240 250 260 270
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
:::::::::::::::::::::::::::: ::::::::::
XP_016 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPA
280 290 300 310 320 330
XP_016 PCLPLCSEPPLGSLLPQGTCLCPSLSFSQPPFLSHLPHPSLLSDHCHCPQASTICLLSTR
340 350 360 370 380 390
>--
initn: 271 init1: 143 opt: 307 Z-score: 405.6 bits: 83.1 E(85289): 7.4e-16
Smith-Waterman score: 307; 45.3% identity (67.5% similar) in 117 aa overlap (83-194:12-126)
60 70 80 90 100 110
pF1KE0 GFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRA
.: : :.:::.:::::: . :. .. .
XP_016 MRFFHWFSKWRKLHRDQEYEVTWYISWSPCTK--CTRDMAT
10 20 30
120 130 140 150 160
pF1KE0 FLQENTHVRLRIFAARIYDY-DPLYKEALQML---RDAG-AQVSIMTYDEFKHCWDTFVD
:: :. .: : ::.::.: . :: :.:::. : ::. : ..::.::::.:::. ::
XP_016 FLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVY
40 50 60 70 80 90
170 180 190
pF1KE0 HQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
: :.::..: .. : : ::
XP_016 SQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVER
100 110 120 130 140 150
>>XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (524 aa)
initn: 557 init1: 454 opt: 802 Z-score: 1059.1 bits: 204.2 E(85289): 3e-52
Smith-Waterman score: 802; 65.1% identity (77.2% similar) in 189 aa overlap (10-195:194-380)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
:: ::: :: :::: :::.::::::
XP_016 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE0 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
:::. : : : ..:.:::: ::: . . :::::: :::..: .:: : :::: :
XP_016 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::: :: :. :...: :: : ::.::::: . .:.:. : .:::..:::::.
XP_016 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
290 300 310 320 330 340
160 170 180 190
pF1KE0 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
:::::::::::::::::::::::::::: ::::::::::
XP_016 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPA
350 360 370 380 390 400
XP_016 PCLPLCSEPPLGSLLPQGTCLCPSLSFSQPPFLSHLPHPSLLSDHCHCPQASTICLLSTR
410 420 430 440 450 460
>--
initn: 295 init1: 143 opt: 348 Z-score: 459.0 bits: 93.2 E(85289): 8e-19
Smith-Waterman score: 348; 38.3% identity (61.7% similar) in 188 aa overlap (18-194:17-193)
10 20 30 40 50
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNG--IGRHKT-YLCYEVERLDNGTSVKMDQH--RGFL
:. :: : ..:..: .::::: . . . .: . :: .
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEV-KTKGPSRPPLDAKIFRGQV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 HNQAKNLLCGFYGRHAELRFLDLVPSL-QLDPAQIYRVTWFISWSPCFSWGCAGEVRAFL
... : : :.::. . .: : :.:::.:::::: . :. .. .::
XP_016 YSELK--------YHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTK--CTRDMATFL
60 70 80 90 100
120 130 140 150 160
pF1KE0 QENTHVRLRIFAARIYDY-DPLYKEALQML---RDAG-AQVSIMTYDEFKHCWDTFVDHQ
:. .: : ::.::.: . :: :.:::. : ::. : ..::.::::.:::. :: :
XP_016 AEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQ
110 120 130 140 150 160
170 180 190
pF1KE0 GCPFQPWDGLDEHSQALSGRLRAILQNQGN
:.::..: .. : : ::
XP_016 RELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMH
170 180 190 200 210 220
>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (442 aa)
initn: 445 init1: 161 opt: 435 Z-score: 575.1 bits: 114.4 E(85289): 2.7e-25
Smith-Waterman score: 435; 39.6% identity (65.1% similar) in 192 aa overlap (9-195:260-442)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNN---GIGRHKTYLCY
: . : :::: .:.: . ::....::.
XP_011 YSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCF
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE0 EVERLDNGTSVKMDQHRGFLHNQAK-NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTW
.: . . . :. .:: ..::. . : ::: ::. . :.: :.:::
XP_011 TMEVVKHHSPVSW--KRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTW
290 300 310 320 330 340
100 110 120 130 140 150
pF1KE0 FISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIM
. ::::: ::::: :: ....: : ::.::.: . : :.:.:. : . ::.: ::
XP_011 YTSWSPCPE--CAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIM
350 360 370 380 390 400
160 170 180 190
pF1KE0 TYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
: .::.::..:: .. ::.:: :: . :...:. ::.
XP_011 GYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
410 420 430 440
>>XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU-edit (455 aa)
initn: 374 init1: 166 opt: 426 Z-score: 563.0 bits: 112.2 E(85289): 1.3e-24
Smith-Waterman score: 426; 40.6% identity (63.5% similar) in 192 aa overlap (9-195:273-455)
10 20 30
pF1KE0 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCY
: . : :::: .:.: . ::....::.
XP_016 CNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCF
250 260 270 280 290 300
40 50 60 70 80 90
pF1KE0 EVERLDNGTSVKMDQHRGFLHNQAK-NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTW
.: . ..: ..:: ..::. . : ::: ::. . :.: :.:::
XP_016 TMEVTKHHSAVF--RKRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTW
310 320 330 340 350
100 110 120 130 140 150
pF1KE0 FISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSIM
. ::::: ::::: :: ....: : ::.::. : .: :.:.: : . ::.:.::
XP_016 YTSWSPCPE--CAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIM
360 370 380 390 400 410
160 170 180 190
pF1KE0 TYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
: .: :: .:: . ::.:: ::. . . :. ::: :::
XP_016 GYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ
420 430 440 450
199 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:01:20 2016 done: Thu Nov 3 05:01:21 2016
Total Scan time: 5.690 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]