Result of FASTA (omim) for pF1KB6571
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6571, 375 aa
  1>>>pF1KB6571 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2229+/-0.000335; mu= 17.1759+/- 0.021
 mean_var=70.0617+/-14.121, 0's: 0 Z-trim(114.6): 70  B-trim: 0 in 0/53
 Lambda= 0.153227
 statistics sampled from 24517 (24590) to 24517 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.288), width:  16
 Scan time:  7.000

The best scores are:                                      opt bits E(85289)
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 2589 581.4 1.1e-165
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 1383 314.8 2.2e-85
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 1383 314.8 2.2e-85
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513)  313 78.4 4.2e-14
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450)  306 76.8 1.1e-13
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455)  301 75.7 2.4e-13
NP_003229 (OMIM: 190220,614816) transforming growt ( 414)  298 75.0 3.5e-13
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424)  298 75.0 3.6e-13
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240)  295 74.2 3.6e-13
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442)  298 75.0 3.7e-13
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412)  297 74.8 4.1e-13
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412)  297 74.8 4.1e-13
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396)  295 74.3 5.4e-13
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501)  294 74.2 7.6e-13
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501)  294 74.2 7.6e-13
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501)  294 74.2 7.6e-13
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391)  292 73.6 8.4e-13
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390)  290 73.2 1.1e-12
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364)  289 73.0 1.3e-12
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431)  289 73.0 1.4e-12
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239)  282 71.3 2.6e-12
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454)  282 71.5 4.4e-12
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345)  274 69.6 1.2e-11
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345)  274 69.6 1.2e-11
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408)  274 69.7 1.4e-11
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408)  274 69.7 1.4e-11
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408)  274 69.7 1.4e-11
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408)  274 69.7 1.4e-11
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402)  272 69.2 1.8e-11
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427)  272 69.3 1.9e-11
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472)  269 68.6 3.3e-11
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478)  256 65.7 2.5e-10
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429)  250 64.4 5.7e-10
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214)  233 60.4 4.4e-09
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347)  233 60.6 6.5e-09
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392)  231 60.2 9.7e-09
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350)  223 58.4   3e-08
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276)  206 54.5 3.4e-07
NP_001316683 (OMIM: 112265) bone morphogenetic pro ( 417)  207 54.9   4e-07
NP_001275754 (OMIM: 601918) growth/differentiation ( 366)  206 54.6 4.2e-07
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366)  206 54.6 4.2e-07
NP_001275753 (OMIM: 601918) growth/differentiation ( 366)  206 54.6 4.2e-07
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366)  206 54.6 4.2e-07
NP_001275757 (OMIM: 601918) growth/differentiation ( 366)  206 54.6 4.2e-07
NP_001275755 (OMIM: 601918) growth/differentiation ( 366)  206 54.6 4.2e-07
NP_001275756 (OMIM: 601918) growth/differentiation ( 366)  206 54.6 4.2e-07
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366)  206 54.6 4.2e-07
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366)  206 54.6 4.2e-07
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454)  206 54.7   5e-07
XP_011541610 (OMIM: 601918) PREDICTED: growth/diff ( 454)  206 54.7   5e-07


>>NP_005250 (OMIM: 601788,614160) growth/differentiation  (375 aa)
 initn: 2589 init1: 2589 opt: 2589  Z-score: 3095.3  bits: 581.4 E(85289): 1.1e-165
Smith-Waterman score: 2589; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)

               10        20        30        40        50        60
pF1KB6 MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LSKLRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSKLRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIIT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 MPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 KDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 FPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQII
              310       320       330       340       350       360

              370     
pF1KB6 YGKIPAMVVDRCGCS
       :::::::::::::::
NP_005 YGKIPAMVVDRCGCS
              370     

>>XP_006719257 (OMIM: 603936) PREDICTED: growth/differen  (407 aa)
 initn: 1349 init1: 1088 opt: 1383  Z-score: 1654.0  bits: 314.8 E(85289): 2.2e-85
Smith-Waterman score: 1645; 65.1% identity (84.9% similar) in 352 aa overlap (34-375:58-407)

            10        20        30        40        50        60   
pF1KB6 LQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSK
                                     : .: : .:.:::...  :.:.:: :::::
XP_006 PAAAAAAAAAAAAAGVGGERSSRPAPSVAPEPDG-CPVCVWRQHSRELRLESIKSQILSK
        30        40        50        60         70        80      

            70        80        90       100        110       120  
pF1KB6 LRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDD-SSDGSLEDDDYHATTETIITMP
       :::. :::::..:..:::::::::....: .: : :  . .  ::.:.:::::::.:.: 
XP_006 LRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMA
         90       100       110       120       130       140      

            130       140       150       160       170       180  
pF1KB6 TESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKD
        :.:  .:.::.: :: :.:: :....::.:::::.:::::  :.::..::::: ::.  
XP_006 QETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRL-KPLTG
        150       160       170       180       190       200      

                     190       200       210       220       230   
pF1KB6 ---------GTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDEN
                : :.  :::::....  .: ::::: : ::..:..::.:: ::::.:.: .
XP_006 EGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPS
         210       220       230       240       250       260     

           240       250       260       270       280       290   
pF1KB6 GHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAF
       : :::::  ::: .::.::.:..: .. :::::..::::::::.::::::::::::::::
XP_006 GTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAF
         270       280       290       300       310       320     

           300       310       320       330       340       350   
pF1KB6 GWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYF
       ::::::::::::::::::.::..:.:::::::::.:::::::::::::::::::::::::
XP_006 GWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYF
         330       340       350       360       370       380     

           360       370     
pF1KB6 NGKEQIIYGKIPAMVVDRCGCS
       : :.::::::::.:::::::::
XP_006 NDKQQIIYGKIPGMVVDRCGCS
         390       400       

>>NP_005802 (OMIM: 603936) growth/differentiation factor  (407 aa)
 initn: 1349 init1: 1088 opt: 1383  Z-score: 1654.0  bits: 314.8 E(85289): 2.2e-85
Smith-Waterman score: 1645; 65.1% identity (84.9% similar) in 352 aa overlap (34-375:58-407)

            10        20        30        40        50        60   
pF1KB6 LQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSK
                                     : .: : .:.:::...  :.:.:: :::::
NP_005 PAAAAAAAAAAAAAGVGGERSSRPAPSVAPEPDG-CPVCVWRQHSRELRLESIKSQILSK
        30        40        50        60         70        80      

            70        80        90       100        110       120  
pF1KB6 LRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDD-SSDGSLEDDDYHATTETIITMP
       :::. :::::..:..:::::::::....: .: : :  . .  ::.:.:::::::.:.: 
NP_005 LRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMA
         90       100       110       120       130       140      

            130       140       150       160       170       180  
pF1KB6 TESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKD
        :.:  .:.::.: :: :.:: :....::.:::::.:::::  :.::..::::: ::.  
NP_005 QETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRL-KPLTG
        150       160       170       180       190       200      

                     190       200       210       220       230   
pF1KB6 ---------GTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDEN
                : :.  :::::....  .: ::::: : ::..:..::.:: ::::.:.: .
NP_005 EGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPS
         210       220       230       240       250       260     

           240       250       260       270       280       290   
pF1KB6 GHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAF
       : :::::  ::: .::.::.:..: .. :::::..::::::::.::::::::::::::::
NP_005 GTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAF
         270       280       290       300       310       320     

           300       310       320       330       340       350   
pF1KB6 GWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYF
       ::::::::::::::::::.::..:.:::::::::.:::::::::::::::::::::::::
NP_005 GWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYF
         330       340       350       360       370       380     

           360       370     
pF1KB6 NGKEQIIYGKIPAMVVDRCGCS
       : :.::::::::.:::::::::
NP_005 NDKQQIIYGKIPGMVVDRCGCS
         390       400       

>>NP_001709 (OMIM: 112266) bone morphogenetic protein 6   (513 aa)
 initn: 279 init1: 168 opt: 313  Z-score: 374.2  bits: 78.4 E(85289): 4.2e-14
Smith-Waterman score: 351; 30.1% identity (53.6% similar) in 276 aa overlap (140-374:238-512)

     110       120       130       140        150        160       
pF1KB6 DYHATTETIITMPTESDFLMQVDGKPKCCFFKFS-SKIQYNKVVKA-QLWIYLRPVETP-
                                     :::. :.:  ..:: : .. ::   :    
NP_001 FLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEVVTAAEFRIYKDCVMGSF
       210       220       230       240       250       260       

          170       180       190       200       210       220    
pF1KB6 --TTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLG
          : ...: ....  .       . . ..      : :  .:. .. . :.  :. :.:
NP_001 KNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEG-WLEFDITATSNLWVVTPQHNMG
       270       280       290       300        310       320      

          230          240        250              260             
pF1KB6 IEIKALDENG---HDLAVTFPG-PGEDGLNPFL-------EVKVTDT---------PKRS
       ...... ..:   :  :. . :  :    .::.       ::.:  :          .:.
NP_001 LQLSVVTRDGVHVHPRAAGLVGRDGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRN
        330       340       350       360       370       380      

          270              280         290        300       310    
pF1KB6 RRDFGLDC-------DEHSTESR--CCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGECE
       :   . :        : .:.: .  : .. : :.:. .:: ::::::: : ::::.::: 
NP_001 RSTQSQDVARVSSASDYNSSELKTACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECS
        390       400       410       420       430       440      

          320             330       340       350       360        
pF1KB6 FVFLQKYPHTH------LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMV
       : .  ..  :.      :::  ::.    :::.:::.. :..:::. . ..:  :   ::
NP_001 FPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMV
        450       460       470       480       490       500      

      370     
pF1KB6 VDRCGCS
       :  ::: 
NP_001 VRACGCH
        510   

>>NP_878248 (OMIM: 604651) growth/differentiation factor  (450 aa)
 initn: 259 init1: 154 opt: 306  Z-score: 366.6  bits: 76.8 E(85289): 1.1e-13
Smith-Waterman score: 308; 29.8% identity (55.3% similar) in 228 aa overlap (166-374:226-449)

         140       150       160       170        180       190    
pF1KB6 KCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIK-PMKDGTRYTGIRSLKL
                                     :  .:  .:: .  :. .     ..: : .
NP_878 YSRAAEPLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGPVPSPL---ALRRLGF
         200       210       220       230       240          250  

          200       210       220       230        240        250  
pF1KB6 DMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDEN-GHDLAVT-FPGPGEDGLNPF
           : :      .  :...  .. :: :  ::.:  .  :  ::   .: ::    .: 
NP_878 GWPGGGGSAAEERAVLVVSSRTQRKES-LFREIRAQARALGAALASEPLPDPGTGTASPR
            260       270        280       290       300       310 

                  260       270          280       290        300  
pF1KB6 LEV------KVTDTPKRSRRDFGLDCDE-HSTE--SRCCRYPLTVDFEAFGWD-WIIAPK
         .      ... .  :. .  :    . :. .  ::: : :: :::. .::: ::::: 
NP_878 AVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPL
             320       330       340       350       360       370 

            310       320             330       340       350      
pF1KB6 RYKANYCSGECEFVFLQKY-PHTH-----LVHQANPRGSAGPCCTPTKMSPINMLYFNGK
        :.: .: : :.: . ..  : .:     :...  : .. . ::.:...:::..::... 
NP_878 DYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAA
             380       390       400       410       420       430 

        360       370     
pF1KB6 EQIIYGKIPAMVVDRCGCS
       ....: .   :::. ::: 
NP_878 NNVVYKQYEDMVVEACGCR
             440       450

>>NP_001001557 (OMIM: 118100,601147,613094,613703,615360  (455 aa)
 initn: 213 init1: 147 opt: 301  Z-score: 360.6  bits: 75.7 E(85289): 2.4e-13
Smith-Waterman score: 315; 36.2% identity (63.1% similar) in 149 aa overlap (240-374:312-454)

     210       220       230       240        250       260        
pF1KB6 TVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGP-GEDGLNPFLEVKVTDTPKRSRRDF
                                     ..: : :     :.:      .: : ::  
NP_001 TRSQRKNLFAEMREQLGSAEAAGPGAGAEGSWPPPSGAPDARPWLP-----SPGRRRRRT
             290       300       310       320            330      

      270          280         290        300       310       320  
pF1KB6 GLDC---DEHSTESR--CCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQKY-
       ..      .:. .::  : . :: :.:. .::: ::::: .:.: .: : :.: . ..  
NP_001 AFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLE
        340       350       360       370       380       390      

                  330        340       350       360       370     
pF1KB6 PHTH-----LVHQANPRGSAGP-CCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
       : .:     :... .: ::. : ::.:::..::..::... ....: .   :::. ::: 
NP_001 PTNHAIIQTLMNSMDP-GSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR
        400       410        420       430       440       450     

>>NP_003229 (OMIM: 190220,614816) transforming growth fa  (414 aa)
 initn: 360 init1: 113 opt: 298  Z-score: 357.6  bits: 75.0 E(85289): 3.5e-13
Smith-Waterman score: 376; 24.9% identity (51.6% similar) in 397 aa overlap (39-375:24-414)

       10        20        30        40        50        60        
pF1KB6 YIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLET
                                     :..    :  .. :::::. ::::::.: .
NP_003        MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRK-RIEAIRGQILSKLKLTS
                      10        20        30         40        50  

       70           80        90       100       110       120     
pF1KB6 APNI---SKDVIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPT--
        :.     ..:  ...      :.:...   .:  . .    :..:.:     : ::   
NP_003 PPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFF
             60        70        80        90       100       110  

            130       140          150         160       170       
pF1KB6 -ESDFLMQVDGKPKCCFFKFS-SKIQYN--KVVKAQLWIY--LRPVETPTTVFVQILRLI
          . .  .  .:   . .:. : .. :  ..:::.. ..    :        ... ...
NP_003 PSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQIL
            120       130       140       150       160       170  

       180           190       200       210       220             
pF1KB6 KPMKDGT----RYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIK-----
       :  :: :    ::   . .:   .   : : :.::  ....::.. . :::..:.     
NP_003 KS-KDLTSPTQRYIDSKVVKTRAE---GEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPC
             180       190          200       210       220        

               230       240                          250          
pF1KB6 ---------ALDENGHDLAVTFPG--------PGED-----------GLNPFL-------
                 . .....: . : :         :..           : .: :       
NP_003 CTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPS
      230       240       250       260       270       280        

            260       270       280       290        300       310 
pF1KB6 -EVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEA-FGWDWIIAPKRYKANYCSG
        ...  .: .:..: .      ..... ::  :: .::.  .:: ::  :: :.::.:.:
NP_003 YRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAG
      290       300       310       320       330       340        

             320          330       340       350       360        
pF1KB6 ECEFVFLQKYPHTH---LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMV
        : ... .   :..   : .  ::..::.:::.   . :...::. ::   :  ..  :.
NP_003 ACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIE-QLSNMI
      350       360       370       380       390       400        

      370     
pF1KB6 VDRCGCS
       :  : ::
NP_003 VKSCKCS
       410    

>>NP_055297 (OMIM: 608748) bone morphogenetic protein 10  (424 aa)
 initn: 307 init1: 136 opt: 298  Z-score: 357.4  bits: 75.0 E(85289): 3.6e-13
Smith-Waterman score: 298; 35.4% identity (57.6% similar) in 158 aa overlap (226-374:278-423)

         200       210       220       230       240        250    
pF1KB6 MNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFP-GPGEDGLNPFLE
                                     ..  ::. : :   .:  ::::..:  .  
NP_055 KHNPLLIVFSDDQSSDKERKEELNEMISHEQLPELDNLGLD---SFSSGPGEEALLQMRS
       250       260       270       280          290       300    

          260       270       280       290        300       310   
pF1KB6 VKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGEC
         . :.  : ::.        .  . : : :: .::. .::: :::::  :.:  : : :
NP_055 NIIYDSTARIRRN--------AKGNYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVC
          310               320       330       340       350      

           320             330       340       350       360       
pF1KB6 EFVFLQKY-PHTH-----LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYG-KIPA
       .. . ..  :  :     :::  : . ..  ::.:::. ::..::.. :  . :  :  .
NP_055 NYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISILYLD-KGVVTYKFKYEG
        360       370       380       390       400        410     

        370     
pF1KB6 MVVDRCGCS
       :.:..::: 
NP_055 MAVSECGCR
         420    

>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b  (240 aa)
 initn: 290 init1: 134 opt: 295  Z-score: 357.4  bits: 74.2 E(85289): 3.6e-13
Smith-Waterman score: 341; 30.5% identity (57.1% similar) in 226 aa overlap (171-374:15-239)

              150       160       170       180       190          
pF1KB6 KFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDM-NPG
                                     ..: ..:::   ....   : :   . : .
XP_011                 MQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQN
                               10        20        30        40    

     200       210       220         230           240             
pF1KB6 TGIWQSIDVKTVLQNWLKQPESNLG--IEIKALDE----NGHDLAVTFPGPGEDG----L
       .. :.:.::  ... :  : ..: :  .:.  :.:    . . . ..     ..     .
XP_011 ASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQI
           50        60        70        80        90       100    

     250            260       270       280       290        300   
pF1KB6 NPFL-----EVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGW-DWIIAPKR
        :.:     . :     :: .:. .   ...  .: : :.:: :::   :: :::.::  
XP_011 RPLLVTFGHDGKGHPLHKREKRQ-AKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPG
          110       120        130       140       150       160   

           310       320        330           340       350        
pF1KB6 YKANYCSGECEFVFLQKYPHT-HLVHQA--NPRGSAGP--CCTPTKMSPINMLYFNGKEQ
       :.: :: ::: : . ..   : : . :.  :  .:  :  ::.::..: :.:::.. .:.
XP_011 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEK
           170       180       190       200       210       220   

      360       370     
pF1KB6 IIYGKIPAMVVDRCGCS
       ..  .   :::. ::: 
XP_011 VVLKNYQDMVVEGCGCR
           230       240

>>NP_001129071 (OMIM: 190220,614816) transforming growth  (442 aa)
 initn: 360 init1: 113 opt: 298  Z-score: 357.2  bits: 75.0 E(85289): 3.7e-13
Smith-Waterman score: 338; 23.8% identity (49.8% similar) in 412 aa overlap (52-375:36-442)

              30        40        50        60        70           
pF1KB6 DLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNI---SKDVIR
                                     :::::. ::::::.: . :.     ..:  
NP_001 LSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP
          10        20        30        40        50        60     

       80        90       100       110                      120   
pF1KB6 QLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHAT------------TETI---ITMPT
       ...      :.:...   .:  . .    :..:.:             .::.   .: :.
NP_001 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPVVTTPS
          70        80        90       100       110       120     

                     130       140                150         160  
pF1KB6 ---------ESDFLM-QVDGKPKCCFFKFSSKIQYN---------KVVKAQLWIY--LRP
                .:. :   .:. :   .  .   ....         ..:::.. ..    :
NP_001 GSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNP
         130       140       150       160       170       180     

            170       180           190       200       210        
pF1KB6 VETPTTVFVQILRLIKPMKDGT----RYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQ
               ... ...:  :: :    ::   . .:   .   : : :.::  ....::..
NP_001 KARVPEQRIELYQILKS-KDLTSPTQRYIDSKVVKTRAE---GEWLSFDVTDAVHEWLHH
         190       200        210       220          230       240 

      220                     230       240                        
pF1KB6 PESNLGIEIK--------------ALDENGHDLAVTFPG--------PGED---------
        . :::..:.               . .....: . : :         :..         
NP_001 KDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKK
             250       260       270       280       290       300 

         250               260       270       280       290       
pF1KB6 --GLNPFL--------EVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEA-FGWD
         : .: :        ...  .: .:..: .      ..... ::  :: .::.  .:: 
NP_001 NSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWK
             310       320       330       340       350       360 

        300       310       320          330       340       350   
pF1KB6 WIIAPKRYKANYCSGECEFVFLQKYPHTH---LVHQANPRGSAGPCCTPTKMSPINMLYF
       ::  :: :.::.:.: : ... .   :..   : .  ::..::.:::.   . :...::.
NP_001 WIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYY
             370       380       390       400       410       420 

           360       370     
pF1KB6 NGKEQIIYGKIPAMVVDRCGCS
        ::   :  ..  :.:  : ::
NP_001 IGKTPKIE-QLSNMIVKSCKCS
              430       440  




375 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:58:13 2016 done: Sat Nov  5 16:58:14 2016
 Total Scan time:  7.000 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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