Result of FASTA (omim) for pF1KB0441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0441, 444 aa
  1>>>pF1KB0441 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5498+/-0.000427; mu= 15.9506+/- 0.026
 mean_var=63.9686+/-12.692, 0's: 0 Z-trim(110.3): 28  B-trim: 0 in 0/50
 Lambda= 0.160358
 statistics sampled from 18557 (18579) to 18557 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.218), width:  16
 Scan time:  6.590

The best scores are:                                      opt bits E(85289)
XP_016880447 (OMIM: 182144) PREDICTED: serine hydr ( 444) 2950 691.6 1.1e-198
NP_683718 (OMIM: 182144) serine hydroxymethyltrans ( 444) 2950 691.6 1.1e-198
XP_016880448 (OMIM: 182144) PREDICTED: serine hydr ( 306) 2016 475.4 8.7e-134
NP_004160 (OMIM: 182144) serine hydroxymethyltrans ( 483) 1846 436.2 9.1e-122
XP_005256824 (OMIM: 182144) PREDICTED: serine hydr ( 483) 1846 436.2 9.1e-122
XP_016880446 (OMIM: 182144) PREDICTED: serine hydr ( 483) 1846 436.2 9.1e-122
XP_011522294 (OMIM: 182144) PREDICTED: serine hydr ( 403) 1841 435.0 1.7e-121
NP_001159829 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_001159830 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_001159831 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_005403 (OMIM: 138450) serine hydroxymethyltrans ( 504) 1256 299.7 1.2e-80
NP_001268715 (OMIM: 182144) serine hydroxymethyltr ( 345) 1117 267.5   4e-71
XP_016880449 (OMIM: 182144) PREDICTED: serine hydr ( 265)  907 218.9 1.3e-56
NP_001159828 (OMIM: 138450) serine hydroxymethyltr ( 494)  804 195.1 3.4e-49
XP_011536977 (OMIM: 138450) PREDICTED: serine hydr ( 408)  589 145.4 2.7e-34
XP_011536980 (OMIM: 138450) PREDICTED: serine hydr ( 408)  589 145.4 2.7e-34
XP_011536979 (OMIM: 138450) PREDICTED: serine hydr ( 408)  589 145.4 2.7e-34
XP_011536978 (OMIM: 138450) PREDICTED: serine hydr ( 408)  589 145.4 2.7e-34


>>XP_016880447 (OMIM: 182144) PREDICTED: serine hydroxym  (444 aa)
 initn: 2950 init1: 2950 opt: 2950  Z-score: 3688.0  bits: 691.6 E(85289): 1.1e-198
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
              370       380       390       400       410       420

              430       440    
pF1KB0 AVQALREEVESFASLFPLPGLPDF
       ::::::::::::::::::::::::
XP_016 AVQALREEVESFASLFPLPGLPDF
              430       440    

>>NP_683718 (OMIM: 182144) serine hydroxymethyltransfera  (444 aa)
 initn: 2950 init1: 2950 opt: 2950  Z-score: 3688.0  bits: 691.6 E(85289): 1.1e-198
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
              370       380       390       400       410       420

              430       440    
pF1KB0 AVQALREEVESFASLFPLPGLPDF
       ::::::::::::::::::::::::
NP_683 AVQALREEVESFASLFPLPGLPDF
              430       440    

>>XP_016880448 (OMIM: 182144) PREDICTED: serine hydroxym  (306 aa)
 initn: 2016 init1: 2016 opt: 2016  Z-score: 2522.8  bits: 475.4 E(85289): 8.7e-134
Smith-Waterman score: 2016; 100.0% identity (100.0% similar) in 306 aa overlap (139-444:1-306)

      110       120       130       140       150       160        
pF1KB0 QCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE
                                     ::::::::::::::::::::::::::::::
XP_016                               MGLDLPDGGHLTHGFMTDKKKISATSIFFE
                                             10        20        30

      170       180       190       200       210       220        
pF1KB0 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD
               40        50        60        70        80        90

      230       240       250       260       270       280        
pF1KB0 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVY
              100       110       120       130       140       150

      290       300       310       320       330       340        
pF1KB0 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN
              160       170       180       190       200       210

      350       360       370       380       390       400        
pF1KB0 TCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKE
              220       230       240       250       260       270

      410       420       430       440    
pF1KB0 FKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
       ::::::::::::::::::::::::::::::::::::
XP_016 FKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
              280       290       300      

>>NP_004160 (OMIM: 182144) serine hydroxymethyltransfera  (483 aa)
 initn: 1846 init1: 1846 opt: 1846  Z-score: 2307.1  bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270                              
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
       :::::::::::::::::::::::::::::::::                           
NP_004 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
              250       260       270       280       290       300

                       280       290       300       310       320 
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_004 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
              430       440       450       460       470       480

          
pF1KB0 PDF
          
NP_004 PDF
          

>>XP_005256824 (OMIM: 182144) PREDICTED: serine hydroxym  (483 aa)
 initn: 1846 init1: 1846 opt: 1846  Z-score: 2307.1  bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270                              
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
       :::::::::::::::::::::::::::::::::                           
XP_005 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
              250       260       270       280       290       300

                       280       290       300       310       320 
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_005 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
              430       440       450       460       470       480

          
pF1KB0 PDF
          
XP_005 PDF
          

>>XP_016880446 (OMIM: 182144) PREDICTED: serine hydroxym  (483 aa)
 initn: 1846 init1: 1846 opt: 1846  Z-score: 2307.1  bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270                              
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
       :::::::::::::::::::::::::::::::::                           
XP_016 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
              250       260       270       280       290       300

                       280       290       300       310       320 
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
              430       440       450       460       470       480

          
pF1KB0 PDF
          
XP_016 PDF
          

>>XP_011522294 (OMIM: 182144) PREDICTED: serine hydroxym  (403 aa)
 initn: 1841 init1: 1841 opt: 1841  Z-score: 2302.1  bits: 435.0 E(85289): 1.7e-121
Smith-Waterman score: 2607; 90.8% identity (90.8% similar) in 444 aa overlap (1-444:1-403)

               10        20        30        40        50        60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
       ::::::::::::::::::::::::::::::::                            
XP_011 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKG----------------------------
              250       260       270                              

              310       320       330       340       350       360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
                    :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
                         280       290       300       310         

              370       380       390       400       410       420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
     320       330       340       350       360       370         

              430       440    
pF1KB0 AVQALREEVESFASLFPLPGLPDF
       ::::::::::::::::::::::::
XP_011 AVQALREEVESFASLFPLPGLPDF
     380       390       400   

>>NP_001159829 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 1816 init1: 1256 opt: 1256  Z-score: 1569.4  bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)

                 10        20        30        40        50        
pF1KB0   MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
                                . :.::: :.......:..::  :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
       ::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
       ::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
       : :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
              190       200       210       220       230       240

      240       250       260       270                            
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
        :.::::.:  .::::::::::: :.:.:::::::                         
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
              250       260       270       280       290       300

                         280       290       300       310         
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
                     ::::::: :  :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
              310       320       330       340       350       360

     320       330       340       350       360       370         
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
       .::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
              370       380       390       400       410       420

     380       390       400       410       420        430        
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
       ..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::  ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
              430       440          450       460       470       

      440    
pF1KB0 PGLPDF
       :     
NP_001 PGFDEH
       480   

>>NP_001159830 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 1816 init1: 1256 opt: 1256  Z-score: 1569.4  bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)

                 10        20        30        40        50        
pF1KB0   MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
                                . :.::: :.......:..::  :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
       ::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
       ::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
       : :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
              190       200       210       220       230       240

      240       250       260       270                            
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
        :.::::.:  .::::::::::: :.:.:::::::                         
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
              250       260       270       280       290       300

                         280       290       300       310         
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
                     ::::::: :  :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
              310       320       330       340       350       360

     320       330       340       350       360       370         
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
       .::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
              370       380       390       400       410       420

     380       390       400       410       420        430        
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
       ..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::  ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
              430       440          450       460       470       

      440    
pF1KB0 PGLPDF
       :     
NP_001 PGFDEH
       480   

>>NP_001159831 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 1816 init1: 1256 opt: 1256  Z-score: 1569.4  bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)

                 10        20        30        40        50        
pF1KB0   MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
                                . :.::: :.......:..::  :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
       ::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
       ::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
       : :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
              190       200       210       220       230       240

      240       250       260       270                            
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
        :.::::.:  .::::::::::: :.:.:::::::                         
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
              250       260       270       280       290       300

                         280       290       300       310         
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
                     ::::::: :  :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
              310       320       330       340       350       360

     320       330       340       350       360       370         
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
       .::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
              370       380       390       400       410       420

     380       390       400       410       420        430        
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
       ..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::  ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
              430       440          450       460       470       

      440    
pF1KB0 PGLPDF
       :     
NP_001 PGFDEH
       480   




444 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:52:38 2016 done: Sat Nov  5 16:52:39 2016
 Total Scan time:  6.590 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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