Result of FASTA (omim) for pF1KB6440
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6440, 345 aa
  1>>>pF1KB6440 345 - 345 aa - 345 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6788+/-0.000332; mu= 15.5354+/- 0.021
 mean_var=99.4799+/-19.604, 0's: 0 Z-trim(117.5): 183  B-trim: 0 in 0/54
 Lambda= 0.128590
 statistics sampled from 29414 (29618) to 29414 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.347), width:  16
 Scan time:  8.060

The best scores are:                                      opt bits E(85289)
NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 2474 469.1  6e-132
XP_005245495 (OMIM: 147050,173610) PREDICTED: P-se ( 790)  456 95.1 5.5e-19
XP_005245496 (OMIM: 147050,173610) PREDICTED: P-se ( 790)  456 95.1 5.5e-19
NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830)  456 95.1 5.7e-19
XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830)  456 95.1 5.7e-19
XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830)  456 95.1 5.7e-19
NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597)  431 90.4 1.1e-17
XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597)  431 90.4 1.1e-17
XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597)  431 90.4 1.1e-17
NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610)  427 89.6 1.9e-17
XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768)  426 89.5 2.5e-17
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571)  433 91.4 3.2e-17
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238)  414 87.7 2.6e-16
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595)  414 87.8 2.9e-16
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327)  414 87.9 3.5e-16
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549)  414 87.9 3.6e-16
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564)  414 87.9 3.6e-16
NP_002104 (OMIM: 134371,235400,603075) complement  ( 330)  388 82.1 1.8e-15
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173)  391 83.4 4.9e-15
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463)  391 83.6 6.9e-15
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507)  391 83.6 6.9e-15
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577)  391 83.6   7e-15
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603)  391 83.6 7.1e-15
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637)  391 83.6 7.1e-15
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667)  391 83.6 7.2e-15
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681)  391 83.6 7.2e-15
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707)  391 83.6 7.2e-15
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538)  387 82.9 1.2e-14
NP_000565 (OMIM: 125240,613793) complement decay-a ( 381)  370 78.9   2e-14
NP_001287833 (OMIM: 125240,613793) complement deca ( 384)  370 78.9 2.1e-14
XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412)  370 78.9 2.2e-14
NP_001287832 (OMIM: 125240,613793) complement deca ( 439)  370 78.9 2.3e-14
NP_001108224 (OMIM: 125240,613793) complement deca ( 440)  370 78.9 2.3e-14
NP_001287831 (OMIM: 125240,613793) complement deca ( 444)  370 78.9 2.3e-14
XP_011507586 (OMIM: 134580,613235) PREDICTED: coag ( 675)  371 79.3 2.7e-14
XP_011507588 (OMIM: 134580,613235) PREDICTED: coag ( 628)  369 78.9 3.3e-14
NP_001985 (OMIM: 134580,613235) coagulation factor ( 661)  369 78.9 3.5e-14
XP_011507585 (OMIM: 134580,613235) PREDICTED: coag ( 676)  369 78.9 3.5e-14
XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362)  378 81.2 3.6e-14
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506)  378 81.2 3.7e-14
XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566)  378 81.2 3.7e-14
XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567)  378 81.2 3.7e-14
XP_016856798 (OMIM: 120920,612922) PREDICTED: memb ( 363)  365 77.9 3.8e-14
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606)  378 81.2 3.8e-14
XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607)  378 81.2 3.8e-14
XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607)  378 81.2 3.8e-14
XP_011507866 (OMIM: 120920,612922) PREDICTED: memb ( 370)  365 77.9 3.8e-14
XP_016856799 (OMIM: 120920,612922) PREDICTED: memb ( 348)  363 77.5 4.7e-14
NP_758871 (OMIM: 120920,612922) membrane cofactor  ( 355)  363 77.5 4.8e-14
XP_016856797 (OMIM: 120920,612922) PREDICTED: memb ( 378)  363 77.6   5e-14


>>NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 precurs  (345 aa)
 initn: 2474 init1: 2474 opt: 2474  Z-score: 2489.9  bits: 469.1 E(85289): 6e-132
Smith-Waterman score: 2474; 99.7% identity (100.0% similar) in 345 aa overlap (1-345:1-345)

               10        20        30        40        50        60
pF1KB6 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 DGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC
       :::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_000 DGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFC
              250       260       270       280       290       300

              310       320       330       340     
pF1KB6 KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
       :::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
              310       320       330       340     

>>XP_005245495 (OMIM: 147050,173610) PREDICTED: P-select  (790 aa)
 initn: 391 init1: 196 opt: 456  Z-score: 461.9  bits: 95.1 E(85289): 5.5e-19
Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572)

                                 10        20        30        40  
pF1KB6                   MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE
                                     .:. :.  .    :..  .. : :: .:  
XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A
       290       300       310       320        330       340      

             50        60        70             80        90       
pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY
        :    . :.:::  :: .  . :  .: :  :. :   ..: :   :  : .. .    
XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL
         350       360        370       380       390       400    

       100       110       120       130       140       150       
pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK
        .:.: .. :: :  ::.: ::: ..: . :.:.   :::  . :    .:. : .   .
XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH
           410       420       430       440       450       460   

       160       170       180       190        200        210     
pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF
       : ..    :...  : :     . : ... : . :::...: ::. . : :. : :.:: 
XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT
             470       480       490       500       510        520

         220         230       240       250        260        270 
pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA
       ..  ..:  .  ::.   : : .::::.:::...::. : :. . : :.: .:       
XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE
               530       540       550       560       570         

             280       290       300       310       320       330 
pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS
                                                                   
XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG
     580       590       600       610       620       630         

>--
 initn: 240 init1: 140 opt: 194  Z-score: 199.2  bits: 46.5 E(85289): 0.00023
Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314)

       80        90       100       110        120        130      
pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV
                                     ::.  :  :.   .  :.   : ..::   
XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE---
        140       150       160       170       180       190      

        140        150       160       170       180       190     
pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT
       :  .  :    .:  . .   .:  :: : . .   :.:   . . : . . : . : ::
XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT
           200       210        220        230       240       250 

          200       210         220       230       240       250  
pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG
        : :.:  ..::  . :. : ..  . :: .. .... .:.:..:..: ::: ..::  :
XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG
             260       270       280        290       300       310

            260       270       280       290       300       310  
pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED
        :.:                                                        
XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID
              320       330       340       350       360       370

>>XP_005245496 (OMIM: 147050,173610) PREDICTED: P-select  (790 aa)
 initn: 391 init1: 196 opt: 456  Z-score: 461.9  bits: 95.1 E(85289): 5.5e-19
Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572)

                                 10        20        30        40  
pF1KB6                   MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE
                                     .:. :.  .    :..  .. : :: .:  
XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A
       290       300       310       320        330       340      

             50        60        70             80        90       
pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY
        :    . :.:::  :: .  . :  .: :  :. :   ..: :   :  : .. .    
XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL
         350       360        370       380       390       400    

       100       110       120       130       140       150       
pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK
        .:.: .. :: :  ::.: ::: ..: . :.:.   :::  . :    .:. : .   .
XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH
           410       420       430       440       450       460   

       160       170       180       190        200        210     
pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF
       : ..    :...  : :     . : ... : . :::...: ::. . : :. : :.:: 
XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT
             470       480       490       500       510        520

         220         230       240       250        260        270 
pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA
       ..  ..:  .  ::.   : : .::::.:::...::. : :. . : :.: .:       
XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE
               530       540       550       560       570         

             280       290       300       310       320       330 
pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS
                                                                   
XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG
     580       590       600       610       620       630         

>--
 initn: 240 init1: 140 opt: 194  Z-score: 199.2  bits: 46.5 E(85289): 0.00023
Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314)

       80        90       100       110        120        130      
pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV
                                     ::.  :  :.   .  :.   : ..::   
XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE---
        140       150       160       170       180       190      

        140        150       160       170       180       190     
pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT
       :  .  :    .:  . .   .:  :: : . .   :.:   . . : . . : . : ::
XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT
           200       210        220        230       240       250 

          200       210         220       230       240       250  
pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG
        : :.:  ..::  . :. : ..  . :: .. .... .:.:..:..: ::: ..::  :
XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG
             260       270       280        290       300       310

            260       270       280       290       300       310  
pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED
        :.:                                                        
XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID
              320       330       340       350       360       370

>>NP_002996 (OMIM: 147050,173610) P-selectin precursor [  (830 aa)
 initn: 391 init1: 196 opt: 456  Z-score: 461.6  bits: 95.1 E(85289): 5.7e-19
Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572)

                                 10        20        30        40  
pF1KB6                   MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE
                                     .:. :.  .    :..  .. : :: .:  
NP_002 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A
       290       300       310       320        330       340      

             50        60        70             80        90       
pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY
        :    . :.:::  :: .  . :  .: :  :. :   ..: :   :  : .. .    
NP_002 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL
         350       360        370       380       390       400    

       100       110       120       130       140       150       
pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK
        .:.: .. :: :  ::.: ::: ..: . :.:.   :::  . :    .:. : .   .
NP_002 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH
           410       420       430       440       450       460   

       160       170       180       190        200        210     
pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF
       : ..    :...  : :     . : ... : . :::...: ::. . : :. : :.:: 
NP_002 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT
             470       480       490       500       510        520

         220         230       240       250        260        270 
pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA
       ..  ..:  .  ::.   : : .::::.:::...::. : :. . : :.: .:       
NP_002 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE
               530       540       550       560       570         

             280       290       300       310       320       330 
pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS
                                                                   
NP_002 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG
     580       590       600       610       620       630         

>--
 initn: 240 init1: 140 opt: 194  Z-score: 198.9  bits: 46.5 E(85289): 0.00024
Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314)

       80        90       100       110        120        130      
pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV
                                     ::.  :  :.   .  :.   : ..::   
NP_002 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE---
        140       150       160       170       180       190      

        140        150       160       170       180       190     
pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT
       :  .  :    .:  . .   .:  :: : . .   :.:   . . : . . : . : ::
NP_002 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT
           200       210        220        230       240       250 

          200       210         220       230       240       250  
pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG
        : :.:  ..::  . :. : ..  . :: .. .... .:.:..:..: ::: ..::  :
NP_002 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG
             260       270       280        290       300       310

            260       270       280       290       300       310  
pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED
        :.:                                                        
NP_002 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID
              320       330       340       350       360       370

>>XP_005245493 (OMIM: 147050,173610) PREDICTED: P-select  (830 aa)
 initn: 391 init1: 196 opt: 456  Z-score: 461.6  bits: 95.1 E(85289): 5.7e-19
Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572)

                                 10        20        30        40  
pF1KB6                   MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE
                                     .:. :.  .    :..  .. : :: .:  
XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A
       290       300       310       320        330       340      

             50        60        70             80        90       
pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY
        :    . :.:::  :: .  . :  .: :  :. :   ..: :   :  : .. .    
XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL
         350       360        370       380       390       400    

       100       110       120       130       140       150       
pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK
        .:.: .. :: :  ::.: ::: ..: . :.:.   :::  . :    .:. : .   .
XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH
           410       420       430       440       450       460   

       160       170       180       190        200        210     
pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF
       : ..    :...  : :     . : ... : . :::...: ::. . : :. : :.:: 
XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT
             470       480       490       500       510        520

         220         230       240       250        260        270 
pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA
       ..  ..:  .  ::.   : : .::::.:::...::. : :. . : :.: .:       
XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE
               530       540       550       560       570         

             280       290       300       310       320       330 
pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS
                                                                   
XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG
     580       590       600       610       620       630         

>--
 initn: 240 init1: 140 opt: 194  Z-score: 198.9  bits: 46.5 E(85289): 0.00024
Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314)

       80        90       100       110        120        130      
pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV
                                     ::.  :  :.   .  :.   : ..::   
XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE---
        140       150       160       170       180       190      

        140        150       160       170       180       190     
pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT
       :  .  :    .:  . .   .:  :: : . .   :.:   . . : . . : . : ::
XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT
           200       210        220        230       240       250 

          200       210         220       230       240       250  
pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG
        : :.:  ..::  . :. : ..  . :: .. .... .:.:..:..: ::: ..::  :
XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG
             260       270       280        290       300       310

            260       270       280       290       300       310  
pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED
        :.:                                                        
XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID
              320       330       340       350       360       370

>>XP_005245492 (OMIM: 147050,173610) PREDICTED: P-select  (830 aa)
 initn: 391 init1: 196 opt: 456  Z-score: 461.6  bits: 95.1 E(85289): 5.7e-19
Smith-Waterman score: 456; 30.8% identity (56.7% similar) in 263 aa overlap (13-264:318-572)

                                 10        20        30        40  
pF1KB6                   MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYE
                                     .:. :.  .    :..  .. : :: .:  
XP_005 CSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK-AVQCQHLEAPSEGTMDCVHPLTAF-A
       290       300       310       320        330       340      

             50        60        70             80        90       
pF1KB6 PGEEITYSCKPGYVSRGGMRKFICPLTGLW--PINT---LKCTPRVCPFAGILENGAVRY
        :    . :.:::  :: .  . :  .: :  :. :   ..: :   :  : .. .    
XP_005 YGSSCKFECQPGYRVRG-LDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSP-SL
         350       360        370       380       390       400    

       100       110       120       130       140       150       
pF1KB6 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK
        .:.: .. :: :  ::.: ::: ..: . :.:.   :::  . :    .:. : .   .
XP_005 RAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH
           410       420       430       440       450       460   

       160       170       180       190        200        210     
pF1KB6 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP-ECREVKC-PFPSRPDNGF
       : ..    :...  : :     . : ... : . :::...: ::. . : :. : :.:: 
XP_005 PFGAFR--YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS-PQNGT
             470       480       490       500       510        520

         220         230       240       250        260        270 
pF1KB6 VNYPAKP--TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SCKLPVKKA
       ..  ..:  .  ::.   : : .::::.:::...::. : :. . : :.: .:       
XP_005 MTC-VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPE
               530       540       550       560       570         

             280       290       300       310       320       330 
pF1KB6 TVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSS
                                                                   
XP_005 QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG
     580       590       600       610       620       630         

>--
 initn: 240 init1: 140 opt: 194  Z-score: 198.9  bits: 46.5 E(85289): 0.00024
Smith-Waterman score: 215; 27.9% identity (55.2% similar) in 154 aa overlap (109-256:167-314)

       80        90       100       110        120        130      
pF1KB6 CTPRVCPFAGILENGAVRYTTFEYPNTISFSCNT-GFYLNGADSAKCT-EEGKWSPELPV
                                     ::.  :  :.   .  :.   : ..::   
XP_005 KSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPE---
        140       150       160       170       180       190      

        140        150       160       170       180       190     
pF1KB6 CAPII-CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT
       :  .  :    .:  . .   .:  :: : . .   :.:   . . : . . : . : ::
XP_005 CEYVRECGELELPQHVLMNCSHP-LGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIWT
           200       210        220        230       240       250 

          200       210         220       230       240       250  
pF1KB6 -KLPECREVKCPFPSRPDNGFVN--YPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG
        : :.:  ..::  . :. : ..  . :: .. .... .:.:..:..: ::: ..::  :
XP_005 NKPPQCLAAQCPPLKIPERGNMTCLHSAK-AFQHQSSCSFSCEEGFALVGPEVVQCTASG
             260       270       280        290       300       310

            260       270       280       290       300       310  
pF1KB6 NWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTED
        :.:                                                        
XP_005 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID
              320       330       340       350       360       370

>>NP_000706 (OMIM: 120830) C4b-binding protein alpha cha  (597 aa)
 initn: 285 init1: 120 opt: 431  Z-score: 438.4  bits: 90.4 E(85289): 1.1e-17
Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303)

                             10        20        30           40   
pF1KB6               MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP
                                     :. : .:  :  : :.. . .   .: .. 
NP_000 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT
           20        30        40         50        60        70   

            50        60        70        80        90        100  
pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY
       :  . :.: ::::   . . . :   : :  ::. :  . :   : :.:: :.  : . .
NP_000 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF
            80        90       100        110       120       130  

            110       120          130       140        150        
pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP
        . : :::. ::.: :. ...:  . .   ::  :: :  . : :::.:      :  . 
NP_000 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH
            140       150       160       170       180            

      160        170       180           190        200       210  
pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD
       :. .:   :  .... : :. ...:. .:.::    : : :   :  :... :    .::
NP_000 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD
        190       200       210       220       230          240   

              220       230       240       250        260         
pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP
         .: .     :   :::  .: :. :. : :   :.:   ..:. . :.:.  :: .::
NP_000 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP
           250       260       270       280       290       300   

       270       280       290       300       310       320       
pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK
                                                                   
NP_000 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL
           310       320       330       340       350       360   

>--
 initn: 159 init1:  96 opt: 286  Z-score: 293.0  bits: 63.5 E(85289): 1.4e-09
Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539)

          10        20        30         40        50         60   
pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK
                                     : :   :  :  . : :.:::  .      
NP_000 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT
         290       300       310       320       330       340     

            70         80        90                100       110   
pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG
        ::  .  : : .   :    ::    :.:: .          . .. : . :::::.  
NP_000 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET
         350         360        370       380       390       400  

           120       130       140       150       160       170   
pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE
         .    :: :  .: :::. : :. :   ::.:        :: :. . :....  ..:
NP_000 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE
                410       420       430           440        450   

           180       190        200       210       220       230  
pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF
       :   . . :.  ..:. ...:.   :.:. . :  :    :: ..   :      ...:.
NP_000 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI
           460        470       480        490         500         

            240       250        260       270       280       290 
pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML
        : .::.. ::. : :.   .:   .:.:.                              
NP_000 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL
     510       520       530       540       550       560         

>>XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding pro  (597 aa)
 initn: 285 init1: 120 opt: 431  Z-score: 438.4  bits: 90.4 E(85289): 1.1e-17
Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303)

                             10        20        30           40   
pF1KB6               MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP
                                     :. : .:  :  : :.. . .   .: .. 
XP_005 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT
           20        30        40         50        60        70   

            50        60        70        80        90        100  
pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY
       :  . :.: ::::   . . . :   : :  ::. :  . :   : :.:: :.  : . .
XP_005 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF
            80        90       100        110       120       130  

            110       120          130       140        150        
pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP
        . : :::. ::.: :. ...:  . .   ::  :: :  . : :::.:      :  . 
XP_005 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH
            140       150       160       170       180            

      160        170       180           190        200       210  
pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD
       :. .:   :  .... : :. ...:. .:.::    : : :   :  :... :    .::
XP_005 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD
        190       200       210       220       230          240   

              220       230       240       250        260         
pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP
         .: .     :   :::  .: :. :. : :   :.:   ..:. . :.:.  :: .::
XP_005 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP
           250       260       270       280       290       300   

       270       280       290       300       310       320       
pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK
                                                                   
XP_005 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL
           310       320       330       340       350       360   

>--
 initn: 159 init1:  96 opt: 286  Z-score: 293.0  bits: 63.5 E(85289): 1.4e-09
Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539)

          10        20        30         40        50         60   
pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK
                                     : :   :  :  . : :.:::  .      
XP_005 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT
         290       300       310       320       330       340     

            70         80        90                100       110   
pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG
        ::  .  : : .   :    ::    :.:: .          . .. : . :::::.  
XP_005 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET
         350         360        370       380       390       400  

           120       130       140       150       160       170   
pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE
         .    :: :  .: :::. : :. :   ::.:        :: :. . :....  ..:
XP_005 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE
                410       420       430           440        450   

           180       190        200       210       220       230  
pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF
       :   . . :.  ..:. ...:.   :.:. . :  :    :: ..   :      ...:.
XP_005 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI
           460        470       480        490         500         

            240       250        260       270       280       290 
pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML
        : .::.. ::. : :.   .:   .:.:.                              
XP_005 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL
     510       520       530       540       550       560         

>>XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding pro  (597 aa)
 initn: 285 init1: 120 opt: 431  Z-score: 438.4  bits: 90.4 E(85289): 1.1e-17
Smith-Waterman score: 431; 30.7% identity (53.7% similar) in 270 aa overlap (17-267:45-303)

                             10        20        30           40   
pF1KB6               MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPL---KTFYEP
                                     :. : .:  :  : :.. . .   .: .. 
XP_005 RKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKT
           20        30        40         50        60        70   

            50        60        70        80        90        100  
pF1KB6 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY
       :  . :.: ::::   . . . :   : :  ::. :  . :   : :.:: :.  : . .
XP_005 GTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGELRNGQVEIKTDLSF
            80        90       100        110       120       130  

            110       120          130       140        150        
pF1KB6 PNTISFSCNTGFYLNGADSAKCTEEGK---WSPELPVCAPIIC-PPPSIPTFATLRVYKP
        . : :::. ::.: :. ...:  . .   ::  :: :  . : :::.:      :  . 
XP_005 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI------RNGRH
            140       150       160       170       180            

      160        170       180           190        200       210  
pF1KB6 SAGNNSL-YRDTAVFECLPQHAMFGNDTITCT----THGNWTKLPE-CREVKCPFPSRPD
       :. .:   :  .... : :. ...:. .:.::    : : :   :  :... :    .::
XP_005 SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITC---RKPD
        190       200       210       220       230          240   

              220       230       240       250        260         
pF1KB6 --NGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMPSCKA-SC-KLP
         .: .     :   :::  .: :. :. : :   :.:   ..:. . :.:.  :: .::
XP_005 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP
           250       260       270       280       290       300   

       270       280       290       300       310       320       
pF1KB6 VKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK
                                                                   
XP_005 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEAL
           310       320       330       340       350       360   

>--
 initn: 159 init1:  96 opt: 286  Z-score: 293.0  bits: 63.5 E(85289): 1.4e-09
Smith-Waterman score: 286; 27.1% identity (49.2% similar) in 240 aa overlap (36-261:316-539)

          10        20        30         40        50         60   
pF1KB6 LILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT-FYEPGEEITYSCKPGYV-SRGGMRK
                                     : :   :  :  . : :.:::  .      
XP_005 KWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTT
         290       300       310       320       330       340     

            70         80        90                100       110   
pF1KB6 FICPLTGLW-PINTLKCTPRVCPFAGILENGAVR---------YTTFEYPNTISFSCNTG
        ::  .  : : .   :    ::    :.:: .          . .. : . :::::.  
XP_005 VICQKNLRWTPYQ--GCEALCCP-EPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHET
         350         360        370       380       390       400  

           120       130       140       150       160       170   
pF1KB6 FYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFE
         .    :: :  .: :::. : :. :   ::.:        :: :. . :....  ..:
XP_005 SRF----SAICQGDGTWSPRTPSCGDICNFPPKIAHGH----YKQSS-SYSFFKEEIIYE
                410       420       430           440        450   

           180       190        200       210       220       230  
pF1KB6 CLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATF
       :   . . :.  ..:. ...:.   :.:. . :  :    :: ..   :      ...:.
XP_005 CDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV-NGRLSVD-KDQYVEPENVTI
           460        470       480        490         500         

            240       250        260       270       280       290 
pF1KB6 GCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGML
        : .::.. ::. : :.   .:   .:.:.                              
XP_005 QCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMAL
     510       520       530       540       550       560         

>>NP_000441 (OMIM: 131210,145500) E-selectin precursor [  (610 aa)
 initn: 454 init1: 158 opt: 427  Z-score: 434.3  bits: 89.6 E(85289): 1.9e-17
Smith-Waterman score: 427; 27.0% identity (54.8% similar) in 341 aa overlap (9-333:169-497)

                                     10        20        30        
pF1KB6                       MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLK
                                     ::.. :.  .   .  .:.   .    :: 
NP_000 YTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLG
      140       150       160       170       180       190        

       40         50        60        70             80        90  
pF1KB6 TF-YEPGEEITYSCKPGYVSRGGMRKFICPLTGLW--PI---NTLKCTPRVCPFAGILEN
       .: :. .  :  ::  ::.  ..:. . :  .: :  ::   :...:   . :  :..: 
NP_000 NFSYNSSCSI--SCDRGYLP-SSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC
      200         210        220       230       240       250     

            100       110       120       130       140       150  
pF1KB6 GAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFAT
             .: . .: .:.:. :: : ::.: .::  :.:. : :.:  . :     :  ..
NP_000 FQ-NPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGS
          260       270       280       290       300       310    

            160       170       180       190        200       210 
pF1KB6 LRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTK-LPECREVKCPFPSRP
       .:  .  ::. . ....  : :     . :   . :::.:.::. .: :.  .:   : :
NP_000 VRCSHSPAGEFT-FKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNP
          320        330       340       350       360       370   

               220       230       240       250        260        
pF1KB6 DNGFVN-YP-AKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNW-SAMPSCKASCKLPV
       . :..:  : :. .. : ..  :.:..:. : : ....:   :.: .  :.:.:      
NP_000 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAV-----
           380       390       400       410       420             

      270         280       290       300       310          320   
pF1KB6 KKATVVYQGER--VKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDG---TIEVP
        .  .:.:  .  :.  ..  . . . .. .: :..  .  . :.  .: .    : :::
NP_000 -RCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQ-LECTSQGQWTEEVP
       430       440       450       460       470        480      

            330       340                                          
pF1KB6 KC-FKEHSSLAFWKTDASDVKPC                                     
       .:   . ::::                                                 
NP_000 SCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPT
        490       500       510       520       530       540      




345 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:40:40 2016 done: Sat Nov  5 16:40:41 2016
 Total Scan time:  8.060 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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