Result of FASTA (omim) for pF1KB5939
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5939, 508 aa
  1>>>pF1KB5939 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7933+/-0.000395; mu= 16.4917+/- 0.025
 mean_var=94.9331+/-18.777, 0's: 0 Z-trim(113.7): 39  B-trim: 59 in 1/52
 Lambda= 0.131633
 statistics sampled from 23092 (23127) to 23092 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.271), width:  16
 Scan time:  8.290

The best scores are:                                      opt bits E(85289)
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 3358 648.4 1.4e-185
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525) 1571 309.1 2.1e-83
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505)  643 132.8 2.3e-30
NP_689534 (OMIM: 610642) endoplasmic reticulum res ( 273)  426 91.4 3.6e-18
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406)  329 73.1 1.7e-12
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229)  318 70.8 4.7e-12
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231)  318 70.8 4.8e-12
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454)  320 71.4 6.1e-12
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324)  279 63.5   1e-09
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  279 63.6 1.3e-09
NP_001287713 (OMIM: 610642) endoplasmic reticulum  ( 172)  273 62.2 1.4e-09
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519)  257 59.5 2.7e-08
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698)  207 50.1 2.5e-05
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166)  197 47.7 3.1e-05
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166)  197 47.7 3.1e-05
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197)  197 47.8 3.5e-05
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402)  201 48.8 3.6e-05
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437)  201 48.8 3.8e-05
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440)  201 48.8 3.8e-05
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445)  201 48.8 3.8e-05
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488)  201 48.9 4.1e-05
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492)  201 48.9 4.2e-05
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604)  194 47.6 0.00012
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747)  194 47.7 0.00014
NP_001222 (OMIM: 114250,616231) calsequestrin-1 pr ( 396)  162 41.4   0.006


>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom  (508 aa)
 initn: 3358 init1: 3358 opt: 3358  Z-score: 3452.7  bits: 648.4 E(85289): 1.4e-185
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)

               10        20        30        40        50        60
pF1KB5 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD
              430       440       450       460       470       480

              490       500        
pF1KB5 DDDLEDLEEAEEPDMEEDDDQKAVKDEL
       ::::::::::::::::::::::::::::
NP_000 DDDLEDLEEAEEPDMEEDDDQKAVKDEL
              490       500        

>>NP_006840 (OMIM: 608012) protein disulfide-isomerase A  (525 aa)
 initn: 1561 init1: 752 opt: 1571  Z-score: 1618.4  bits: 309.1 E(85289): 2.1e-83
Smith-Waterman score: 1571; 50.0% identity (76.5% similar) in 468 aa overlap (18-474:32-495)

                            10        20            30        40   
pF1KB5              MLRRALLCLAVAALVRADAPEEE----DHVLVLRKSNFAEALAAHKY
                                     . ::::    : .::: . ... ::  :  
NP_006 SRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPA
              10        20        30        40        50        60 

            50        60        70        80        90       100   
pF1KB5 LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIK
       :::::::::::::.::::::.:::. : ::.  . :::::.  . .::...::  :::.:
NP_006 LLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK
              70        80        90       100       110       120 

           110       120       130       140       150       160   
pF1KB5 FFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKD
       :::::. . :.:::. :.:. :..::..:.::.:  : : :::..:. . ...:::::.:
NP_006 FFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQD
             130       140       150       160       170       180 

           170       180       190       200       210       220   
pF1KB5 VESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKE
       ......  ::  :.   :. ::.:.   .:... : :: ::::::::::: .:   : .:
NP_006 LQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFP--VDEE
             190       200       210       220       230           

                 230       240       250       260       270       
pF1KB5 NLLD------FIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKT
         ::      :.  ... :: ::. ::. :::...: .:.:::. .... .   :..:  
NP_006 LGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGE
     240       250       260       270       280       290         

       280       290       300       310       320        330      
pF1KB5 AAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKP-ESEELTA
       ::  :.:..::. .:   .::...:..:::: :  :..::..::    :: : ..  .::
NP_006 AAPRFRGQVLFVVVDVA-ADNEHVLQYFGLKAEAAPTLRLVNLETT-KKYAPVDGGPVTA
     300       310        320       330       340        350       

        340       350       360       370       380       390      
pF1KB5 ERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPW
         :: :::  :.:..::.:.:::.: :::..:::.:::::::.::::: :::::.:::::
NP_006 ASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPW
       360       370       380       390       400       410       

        400       410       420       430       440       450      
pF1KB5 CGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVID
       : :::..:: :. :.: :.:::.:.::..:.::::..:  ::.:::::.:::.  : ::.
NP_006 CTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIE
       420       430       440       450       460       470       

        460       470       480       490       500        
pF1KB5 YNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
       :.. : :. :.:::..::                                  
NP_006 YKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL    
       480       490       500       510       520         

>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A  (505 aa)
 initn: 675 init1: 280 opt: 643  Z-score: 666.2  bits: 132.8 E(85289): 2.3e-30
Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (2-471:3-481)

                10        20        30           40        50      
pF1KB5  MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC
         :::  :  .:: :. :      . :: :  .::   ..   .   .::::.:::::::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB5 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY
       : :::::  :: .::.    . ::::: : ...  ..::: ::::.:.::.:. :.   :
NP_005 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AY
               70           80        90       100       110       

        120       130       140       150       160       170      
pF1KB5 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA
        . : :: ::. :::..:::.. :      .... .......::: :  :.. ..::.::
NP_005 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA
         120       130       140       150       160       170     

         180       190       200             210        220        
pF1KB5 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF
         . :.  :. :.  .. ..:. . .:..::.      ::..    . : ..:. ..  :
NP_005 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF
         180       190       200       210       220       230     

      230       240       250       260         270       280      
pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYD--GKLSNFKTAAESFKGKI
       :..: . .  ..::..   : : .     ::.   .: ::.  .: ::.      .....
NP_005 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV
         240       250            260        270             280   

           290       300                310         320       330  
pF1KB5 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE
       ...   :.:. :  :  .         :  :::..   : :.: . : . :   .. :  
NP_005 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS
           290       300       310       320       330       340   

            340       350       360       370       380       390  
pF1KB5 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF
       .  .. . .: . ...:..: .: :. .::. :  ::::.:..::.... .:.:.:..::
NP_005 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF
            350       360       370        380       390       400 

            400       410       420       430        440       450 
pF1KB5 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD
       :::::::::.: : . .:::  .   ::::::::.:::.: .  .:..:::. : ::.  
NP_005 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK
             410       420       430       440       450       460 

             460       470       480       490       500        
pF1KB5 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
        .   :.: : :. : ..:.                                     
NP_005 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL             
             470       480       490       500                  

>>NP_689534 (OMIM: 610642) endoplasmic reticulum residen  (273 aa)
 initn: 318 init1: 156 opt: 426  Z-score: 447.1  bits: 91.4 E(85289): 3.6e-18
Smith-Waterman score: 426; 32.5% identity (65.4% similar) in 231 aa overlap (130-351:29-257)

     100       110       120       130       140           150     
pF1KB5 PTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLP----DGAAAESLVESSEV
                                     :.  ::.:.  :    :  ::  .. ..::
NP_689   MEAAPSRFMFLLFLLTCELAAEVAAEVEKSSDGPGAAQEPTWLTDVPAAMEFIAATEV
                 10        20        30        40        50        

         160       170       180       190       200       210     
pF1KB5 AVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN
       ::::::.:.:  ..  . . .. .  . :::...:.:...:..  . . ::.  :. . :
NP_689 AVIGFFQDLEIPAVPILHSMVQKFPGVSFGISTDSEVLTHYNITGNTICLFRLVDNEQLN
       60        70        80        90       100       110        

             220       230       240       250       260       270 
pF1KB5 FEGE----VTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGK
       .: :    .   .:  ::. :.: .: :..  :.  .:.. :. :.::.. :.  .:. .
NP_689 LEDEDIESIDATKLSRFIEINSLHMVTEYNPVTVIGLFNSVIQIHLLLIMNKASPEYEEN
      120       130       140       150       160       170        

             280       290       300       310        320       330
pF1KB5 LSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLI-TLEEEMTKYKPE
       .  .. ::. :.::::::..::   .: ... :: ::. . ::. .  ::..:     : 
NP_689 MHRYQKAAKLFQGKILFILVDSGMKENGKVISFFKLKESQLPALAIYQTLDDEWDTL-P-
      180       190       200       210       220       230        

              340       350       360       370       380       390
pF1KB5 SEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFV
       . :...:.. .::  :: ::.                                       
NP_689 TAEVSVEHVQNFCDGFLSGKLLKENRESEGKTPKVEL                       
        240       250       260       270                          

>>NP_055866 (OMIM: 609170) endoplasmic reticulum residen  (406 aa)
 initn: 190 init1: 122 opt: 329  Z-score: 345.2  bits: 73.1 E(85289): 1.7e-12
Smith-Waterman score: 340; 23.6% identity (54.9% similar) in 377 aa overlap (26-395:31-392)

                    10        20        30        40        50     
pF1KB5      MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGH
                                     .  :   :. : :      ::.::: ::  
NP_055 MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF
               10        20        30        40        50        60

          60        70           80        90       100       110  
pF1KB5 CKALAPEYAKAAGKLKAE---GSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTAS
        . : : . .:.  .: :    ... .:.::  ..::.::.: .  :::.:.::::    
NP_055 SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG-MMM
               70        80        90       100       110          

            120       130       140       150       160       170  
pF1KB5 PKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQF
        .:: . : .  ........ .     . : :   .: . :.  .::.:.. .::. . :
NP_055 KREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL-DRSKRNIIGYFEQKDSDNYRVF
     120       130       140       150        160       170        

             180       190       200       210         220         
pF1KB5 LQAAEAI-DDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNN--FEGEVTKENLL-DF
        ..:. . ::  : ... .:: .  . . :... .:   ..  .  . : .:. ..  ..
NP_055 ERVANILHDDCAF-LSAFGDVSKPERYSGDNII-YKPPGHSAPDMVYLGAMTNFDVTYNW
      180       190        200       210        220       230      

      230       240       250       260       270       280        
pF1KB5 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILF
       :. . .::: :.: ... ..    .   ::. . ... . .   ..      : :: : :
NP_055 IQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINF
        240       250       260       270       280       290      

      290       300       310       320       330       340        
pF1KB5 IFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLE
       .  : :.  .   :  .     .::.. . .... :  .   .. :   .. .:   .  
NP_055 LHADCDKFRHP--LLHIQKTPADCPVIAIDSFRH-MYVFGDFKDVLIPGKLKQFVFDLHS
        300         310       320        330       340       350   

      350       360       370       380       390       400        
pF1KB5 GKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWD
       ::.  :   .. :.  :  :     :.. .::: .  .. : .. ::             
NP_055 GKL--HREFHHGPDPTDTAP-----GEQAQDVASSPPESSFQKL-APSEYRYTLLRDRDE
             360       370            380       390        400     

      410       420       430       440       450       460        
pF1KB5 KLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKK
                                                                   
NP_055 L                                                           
                                                                   

>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi  (229 aa)
 initn: 288 init1: 249 opt: 318  Z-score: 337.3  bits: 70.8 E(85289): 4.7e-12
Smith-Waterman score: 318; 34.7% identity (64.7% similar) in 167 aa overlap (45-207:45-204)

           20        30        40        50        60        70    
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
                                     ::.:::::::::: : : . ... ..:. :
XP_011 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
           20        30        40        50        60        70    

           80        90       100       110       120       130    
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
       : ....:.:::  :..:...:::::::::... :: :   .: . :  :::... .. .:
XP_011 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
           80        90       100        110         120       130 

          140       150       160         170       180       190  
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
            ::.    : . .  .:    ::  :  ::   .....::  .    . .... .:
XP_011 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
             140       150           160       170       180       

            200         210       220       230       240       250
pF1KB5 FSKYQLDKD--GVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFG
         .:   :.  .:..::                                           
XP_011 VPEYVTLKEMPAVLVFKDETYFVYDDNNYTLMLSYKRYYLHT                  
       190       200       210       220                           

>>XP_011524336 (OMIM: 616102) PREDICTED: protein disulfi  (231 aa)
 initn: 288 init1: 249 opt: 318  Z-score: 337.3  bits: 70.8 E(85289): 4.8e-12
Smith-Waterman score: 318; 34.7% identity (64.7% similar) in 167 aa overlap (45-207:45-204)

           20        30        40        50        60        70    
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
                                     ::.:::::::::: : : . ... ..:. :
XP_011 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
           20        30        40        50        60        70    

           80        90       100       110       120       130    
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
       : ....:.:::  :..:...:::::::::... :: :   .: . :  :::... .. .:
XP_011 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
           80        90       100        110         120       130 

          140       150       160         170       180       190  
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
            ::.    : . .  .:    ::  :  ::   .....::  .    . .... .:
XP_011 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
             140       150           160       170       180       

            200         210       220       230       240       250
pF1KB5 FSKYQLDKD--GVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFG
         .:   :.  .:..::                                           
XP_011 VPEYVTLKEMPAVLVFKDETYFVYDAFILDSESTCAGLLHGCIG                
       190       200       210       220       230                 

>>NP_061895 (OMIM: 616102) protein disulfide-isomerase T  (454 aa)
 initn: 288 init1: 249 opt: 320  Z-score: 335.3  bits: 71.4 E(85289): 6.1e-12
Smith-Waterman score: 320; 31.3% identity (63.6% similar) in 195 aa overlap (45-229:45-232)

           20        30        40        50        60        70    
pF1KB5 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
                                     ::.:::::::::: : : . ... ..:. :
NP_061 TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
           20        30        40        50        60        70    

           80        90       100       110       120       130    
pF1KB5 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
       : ....:.:::  :..:...:::::::::... :: :   .: . :  :::... .. .:
NP_061 SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLA--YNYRGPRTKDDIIEFAHRVSG
           80        90       100        110         120       130 

          140       150       160         170       180       190  
pF1KB5 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
            ::.    : . .  .:    ::  :  ::   .....::  .    . .... .:
NP_061 ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
             140       150           160       170       180       

            200              210        220       230       240    
pF1KB5 FSKYQLDKD--GVVLFKK-----FDEGRN-NFEGEVTKENLLDFIKHNQLPLVIEFTEQT
         .:   :.  .:..::      .:: .. .. . ...: . ...               
NP_061 VPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGK
       190       200       210       220       230       240       

          250       260       270       280       290       300    
pF1KB5 APKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEF
                                                                   
NP_061 LVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVP
       250       260       270       280       290       300       

>>NP_001139021 (OMIM: 616412) thioredoxin domain-contain  (324 aa)
 initn: 426 init1: 235 opt: 279  Z-score: 295.2  bits: 63.5 E(85289): 1e-09
Smith-Waterman score: 279; 39.5% identity (71.1% similar) in 114 aa overlap (13-125:202-312)

                                 10        20         30        40 
pF1KB5                   MLRRALLCLAVAALVRADAPE-EEDHVLVLRKSNFAEALAAH
                                     : : :  :: ..  ::.: ..:: ...: .
NP_001 KRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIA-E
             180       190       200       210       220        230

              50        60        70        80        90       100 
pF1KB5 KYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPT
          ...::::::::::.::: . . . :     . ...:.:: : : .. ..:.::::::
NP_001 GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPT
              240       250       260       270       280       290

             110       120       130       140       150       160 
pF1KB5 IKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFF
       . .::.:  .:  :...::. :..                                    
NP_001 LLLFRGGKKVS--EHSGGRDLDSLHRFVLSQAKDEL                        
              300         310       320                            

>--
 initn: 331 init1: 187 opt: 243  Z-score: 258.3  bits: 56.7 E(85289): 1.2e-07
Smith-Waterman score: 251; 36.4% identity (65.9% similar) in 129 aa overlap (19-141:76-199)

                           10        20        30        40        
pF1KB5             MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEF
                                     ::: .. .  :  ::: :  .:.   ...:
NP_001 PRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNF-ELHVAQGDHFIKF
          50        60        70        80        90        100    

       50        60        70         80        90       100       
pF1KB5 YAPWCGHCKALAPEYAKAAGKLKAEGSE-IRLAKVDATEESDLAQQYGVRGYPTIKFFRN
       .:::::::::::: . . :  :  : :: ....::: :.. .: .   ::::::. .::.
NP_001 FAPWCGHCKALAPTWEQLA--LGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRD
          110       120         130       140       150       160  

       110       120       130            140       150       160  
pF1KB5 GDTASPKEYTAGREADDIVNWLKKR-----TGPAATTLPDGAAAESLVESSEVAVIGFFK
       :  ..  .: . :. ... ......     :: . :. :                     
NP_001 GKKVD--QYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALT
              170       180       190       200       210       220

            170       180       190       200       210       220  
pF1KB5 DVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTK
                                                                   
NP_001 ENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNIC
              230       240       250       260       270       280

>>NP_110437 (OMIM: 616412) thioredoxin domain-containing  (432 aa)
 initn: 492 init1: 235 opt: 279  Z-score: 293.5  bits: 63.6 E(85289): 1.3e-09
Smith-Waterman score: 279; 39.5% identity (71.1% similar) in 114 aa overlap (13-125:310-420)

                                 10        20         30        40 
pF1KB5                   MLRRALLCLAVAALVRADAPE-EEDHVLVLRKSNFAEALAAH
                                     : : :  :: ..  ::.: ..:: ...: .
NP_110 KRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIA-E
     280       290       300       310       320       330         

              50        60        70        80        90       100 
pF1KB5 KYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPT
          ...::::::::::.::: . . . :     . ...:.:: : : .. ..:.::::::
NP_110 GITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPT
      340       350       360       370       380       390        

             110       120       130       140       150       160 
pF1KB5 IKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFF
       . .::.:  .:  :...::. :..                                    
NP_110 LLLFRGGKKVS--EHSGGRDLDSLHRFVLSQAKDEL                        
      400         410       420       430                          

>--
 initn: 406 init1: 187 opt: 243  Z-score: 256.6  bits: 56.8 E(85289): 1.5e-07
Smith-Waterman score: 251; 36.4% identity (65.9% similar) in 129 aa overlap (19-141:184-307)

                           10        20        30        40        
pF1KB5             MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEF
                                     ::: .. .  :  ::: :  .:.   ...:
NP_110 PRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNF-ELHVAQGDHFIKF
           160       170       180       190        200       210  

       50        60        70         80        90       100       
pF1KB5 YAPWCGHCKALAPEYAKAAGKLKAEGSE-IRLAKVDATEESDLAQQYGVRGYPTIKFFRN
       .:::::::::::: . . :  :  : :: ....::: :.. .: .   ::::::. .::.
NP_110 FAPWCGHCKALAPTWEQLA--LGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRD
            220       230         240       250       260       270

       110       120       130            140       150       160  
pF1KB5 GDTASPKEYTAGREADDIVNWLKKR-----TGPAATTLPDGAAAESLVESSEVAVIGFFK
       :  ..  .: . :. ... ......     :: . :. :                     
NP_110 GKKVD--QYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALT
                280       290       300       310       320        

            170       180       190       200       210       220  
pF1KB5 DVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTK
                                                                   
NP_110 ENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNIC
      330       340       350       360       370       380        

>--
 initn: 271 init1: 158 opt: 222  Z-score: 235.0  bits: 52.8 E(85289): 2.4e-06
Smith-Waterman score: 248; 36.4% identity (61.2% similar) in 129 aa overlap (12-129:41-164)

                                  10        20               30    
pF1KB5                    MLRRALLCLAVAALVRADAPEEED-------HVLVLRKSN-
                                     :: . ::.:   :       :   :  .. 
NP_110 LLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADM
               20        30        40        50        60        70

              40        50        60        70         80        90
pF1KB5 FAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKA-EGSEIRLAKVDATEESDL
       :....  :::   .: :.:::::::. : : .   . : .. : ... .:::: : .::.
NP_110 FTHGIQSAAH---FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDV
               80           90       100       110       120       

              100       110       120       130       140       150
pF1KB5 AQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLV
        .  :::::::.:.:. :. :   .: . :. . . ::.                     
NP_110 CSAQGVRGYPTLKLFKPGQEAV--KYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAP
       130       140         150       160       170       180     

              160       170       180       190       200       210
pF1KB5 ESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFD
                                                                   
NP_110 ELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV
         190       200       210       220       230       240     




508 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:38:25 2016 done: Sat Nov  5 15:38:27 2016
 Total Scan time:  8.290 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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