Result of FASTA (omim) for pF1KB5913
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5913, 504 aa
  1>>>pF1KB5913 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6720+/-0.000387; mu= 15.6545+/- 0.024
 mean_var=59.8063+/-12.168, 0's: 0 Z-trim(110.7): 31  B-trim: 999 in 1/55
 Lambda= 0.165844
 statistics sampled from 19037 (19059) to 19037 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.223), width:  16
 Scan time:  9.170

The best scores are:                                      opt bits E(85289)
NP_005403 (OMIM: 138450) serine hydroxymethyltrans ( 504) 3343 808.6       0
NP_001159830 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2       0
NP_001159829 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2       0
NP_001159831 (OMIM: 138450) serine hydroxymethyltr ( 483) 3191 772.2       0
XP_005256824 (OMIM: 182144) PREDICTED: serine hydr ( 483) 2033 495.2 1.8e-139
XP_016880446 (OMIM: 182144) PREDICTED: serine hydr ( 483) 2033 495.2 1.8e-139
NP_004160 (OMIM: 182144) serine hydroxymethyltrans ( 483) 2033 495.2 1.8e-139
XP_011536980 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536977 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536978 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
XP_011536979 (OMIM: 138450) PREDICTED: serine hydr ( 408) 1992 485.4 1.4e-136
NP_001159828 (OMIM: 138450) serine hydroxymethyltr ( 494) 1917 467.4 4.2e-131
NP_001268715 (OMIM: 182144) serine hydroxymethyltr ( 345) 1457 357.3   4e-98
XP_016880447 (OMIM: 182144) PREDICTED: serine hydr ( 444) 1256 309.3 1.5e-83
NP_683718 (OMIM: 182144) serine hydroxymethyltrans ( 444) 1256 309.3 1.5e-83
XP_011522294 (OMIM: 182144) PREDICTED: serine hydr ( 403) 1251 308.1 3.2e-83
XP_016880448 (OMIM: 182144) PREDICTED: serine hydr ( 306)  680 171.4 3.3e-42
XP_016880449 (OMIM: 182144) PREDICTED: serine hydr ( 265)  675 170.2 6.6e-42


>>NP_005403 (OMIM: 138450) serine hydroxymethyltransfera  (504 aa)
 initn: 3343 init1: 3343 opt: 3343  Z-score: 4318.6  bits: 808.6 E(85289):    0
Smith-Waterman score: 3343; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)

               10        20        30        40        50        60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
              430       440       450       460       470       480

              490       500    
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
       ::::::::::::::::::::::::
NP_005 RLANLRQRVEQFARAFPMPGFDEH
              490       500    

>>NP_001159830 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 3191 init1: 3191 opt: 3191  Z-score: 4122.3  bits: 772.2 E(85289):    0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)

               10        20        30        40        50        60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                            :::::::::::::::::::::::::::::::::::::::
NP_001                      MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                                    10        20        30         

               70        80        90       100       110       120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
     280       290       300       310       320       330         

              370       380       390       400       410       420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
     340       350       360       370       380       390         

              430       440       450       460       470       480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
     400       410       420       430       440       450         

              490       500    
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
       ::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
     460       470       480   

>>NP_001159829 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 3191 init1: 3191 opt: 3191  Z-score: 4122.3  bits: 772.2 E(85289):    0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)

               10        20        30        40        50        60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                            :::::::::::::::::::::::::::::::::::::::
NP_001                      MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                                    10        20        30         

               70        80        90       100       110       120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
     280       290       300       310       320       330         

              370       380       390       400       410       420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
     340       350       360       370       380       390         

              430       440       450       460       470       480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
     400       410       420       430       440       450         

              490       500    
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
       ::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
     460       470       480   

>>NP_001159831 (OMIM: 138450) serine hydroxymethyltransf  (483 aa)
 initn: 3191 init1: 3191 opt: 3191  Z-score: 4122.3  bits: 772.2 E(85289):    0
Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 483 aa overlap (22-504:1-483)

               10        20        30        40        50        60
pF1KB5 MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                            :::::::::::::::::::::::::::::::::::::::
NP_001                      MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELL
                                    10        20        30         

               70        80        90       100       110       120
pF1KB5 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KB5 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KB5 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREV
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KB5 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVD
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KB5 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
     280       290       300       310       320       330         

              370       380       390       400       410       420
pF1KB5 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
     340       350       360       370       380       390         

              430       440       450       460       470       480
pF1KB5 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ
     400       410       420       430       440       450         

              490       500    
pF1KB5 RLANLRQRVEQFARAFPMPGFDEH
       ::::::::::::::::::::::::
NP_001 RLANLRQRVEQFARAFPMPGFDEH
     460       470       480   

>>XP_005256824 (OMIM: 182144) PREDICTED: serine hydroxym  (483 aa)
 initn: 2040 init1: 1950 opt: 2033  Z-score: 2625.0  bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)

         20        30        40        50        60        70      
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
                                     . :.::: :.......:..::  :::::::
XP_005        MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
                      10        20        30        40        50   

         80        90       100       110       120       130      
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
       ::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  :::
XP_005 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
            60        70        80        90       100       110   

        140       150       160       170       180       190      
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
       :::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
XP_005 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
           120       130       140       150       160       170   

        200       210       220       230       240       250      
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
       .:: :: :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.:::::::
XP_005 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
           180       190       200       210       220       230   

        260       270       280       290       300       310      
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
       ::::: :.::::.:  .::::::::::: :.:.::::::::.::::::.:: :..:. ::
XP_005 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
           240       250       260       270       280       290   

        320       330       340       350       360       370      
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
        ::::.:::::::::::.:::::::: :  :. :. ::. : ::...:: : ::..:.::
XP_005 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
           300       310       320       330       340       350   

        380       390       400       410       420       430      
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
       .::::.::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: .
XP_005 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
           360       370       380       390       400       410   

        440       450       460          470       480       490   
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
        : ::..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::
XP_005 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
           420       430       440       450       460        470  

           500    
pF1KB5 RAFPMPGFDEH
         ::.::. . 
XP_005 SLFPLPGLPDF
            480   

>>XP_016880446 (OMIM: 182144) PREDICTED: serine hydroxym  (483 aa)
 initn: 2040 init1: 1950 opt: 2033  Z-score: 2625.0  bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)

         20        30        40        50        60        70      
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
                                     . :.::: :.......:..::  :::::::
XP_016        MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
                      10        20        30        40        50   

         80        90       100       110       120       130      
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
       ::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  :::
XP_016 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
            60        70        80        90       100       110   

        140       150       160       170       180       190      
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
       :::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
XP_016 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
           120       130       140       150       160       170   

        200       210       220       230       240       250      
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
       .:: :: :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.:::::::
XP_016 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
           180       190       200       210       220       230   

        260       270       280       290       300       310      
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
       ::::: :.::::.:  .::::::::::: :.:.::::::::.::::::.:: :..:. ::
XP_016 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
           240       250       260       270       280       290   

        320       330       340       350       360       370      
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
        ::::.:::::::::::.:::::::: :  :. :. ::. : ::...:: : ::..:.::
XP_016 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
           300       310       320       330       340       350   

        380       390       400       410       420       430      
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
       .::::.::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: .
XP_016 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
           360       370       380       390       400       410   

        440       450       460          470       480       490   
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
        : ::..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::
XP_016 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
           420       430       440       450       460        470  

           500    
pF1KB5 RAFPMPGFDEH
         ::.::. . 
XP_016 SLFPLPGLPDF
            480   

>>NP_004160 (OMIM: 182144) serine hydroxymethyltransfera  (483 aa)
 initn: 2040 init1: 1950 opt: 2033  Z-score: 2625.0  bits: 495.2 E(85289): 1.8e-139
Smith-Waterman score: 2033; 66.1% identity (85.4% similar) in 460 aa overlap (47-503:24-482)

         20        30        40        50        60        70      
pF1KB5 GQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIAS
                                     . :.::: :.......:..::  :::::::
NP_004        MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIAS
                      10        20        30        40        50   

         80        90       100       110       120       130      
pF1KB5 ENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGV
       ::: :::.::::::::::::::::::.:::::.: .::.: :::.:::.:. :::  :::
NP_004 ENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGV
            60        70        80        90       100       110   

        140       150       160       170       180       190      
pF1KB5 NVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYK
       :::::::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::
NP_004 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK
           120       130       140       150       160       170   

        200       210       220       230       240       250      
pF1KB5 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS
       .:: :: :.:.::  .::::.:.::::::: :.: ..:::.:.. ::  :.:.:::::::
NP_004 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS
           180       190       200       210       220       230   

        260       270       280       290       300       310      
pF1KB5 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRIN
       ::::: :.::::.:  .::::::::::: :.:.::::::::.::::::.:: :..:. ::
NP_004 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLIN
           240       250       260       270       280       290   

        320       330       340       350       360       370      
pF1KB5 FAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG
        ::::.:::::::::::.:::::::: :  :. :. ::. : ::...:: : ::..:.::
NP_004 SAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG
           300       310       320       330       340       350   

        380       390       400       410       420       430      
pF1KB5 TDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQF
       .::::.::::: :: ::.:::.:::  ::. :::::::::::. :.:::::.:::::: .
NP_004 SDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGL
           360       370       380       390       400       410   

        440       450       460          470       480       490   
pF1KB5 REDDFRRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFA
        : ::..:. :: .:... :...: :   : :..::  :  :.  .   : ::..::.::
NP_004 LEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFA
           420       430       440       450       460        470  

           500    
pF1KB5 RAFPMPGFDEH
         ::.::. . 
NP_004 SLFPLPGLPDF
            480   

>>XP_011536980 (OMIM: 138450) PREDICTED: serine hydroxym  (408 aa)
 initn: 2013 init1: 1987 opt: 1992  Z-score: 2573.2  bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)

         140       150       160       170       180       190     
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
                                     : ..:.  .   :..  ::.:..   ..  
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
             50        60        70        80        90            

         200       210       220       230       240       250     
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
       ...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
     100       110       120       130       140       150         

         260       270       280       290       300       310     
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
     160       170       180       190       200       210         

         320       330       340       350       360       370     
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
     220       230       240       250       260       270         

         380       390       400       410       420       430     
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
     280       290       300       310       320       330         

         440       450       460       470       480       490     
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
     340       350       360       370       380       390         

         500    
pF1KB5 FPMPGFDEH
       :::::::::
XP_011 FPMPGFDEH
     400        

>>XP_011536977 (OMIM: 138450) PREDICTED: serine hydroxym  (408 aa)
 initn: 2013 init1: 1987 opt: 1992  Z-score: 2573.2  bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)

         140       150       160       170       180       190     
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
                                     : ..:.  .   :..  ::.:..   ..  
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
             50        60        70        80        90            

         200       210       220       230       240       250     
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
       ...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
     100       110       120       130       140       150         

         260       270       280       290       300       310     
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
     160       170       180       190       200       210         

         320       330       340       350       360       370     
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
     220       230       240       250       260       270         

         380       390       400       410       420       430     
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
     280       290       300       310       320       330         

         440       450       460       470       480       490     
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
     340       350       360       370       380       390         

         500    
pF1KB5 FPMPGFDEH
       :::::::::
XP_011 FPMPGFDEH
     400        

>>XP_011536978 (OMIM: 138450) PREDICTED: serine hydroxym  (408 aa)
 initn: 2013 init1: 1987 opt: 1992  Z-score: 2573.2  bits: 485.4 E(85289): 1.4e-136
Smith-Waterman score: 1992; 92.0% identity (96.2% similar) in 339 aa overlap (166-504:73-408)

         140       150       160       170       180       190     
pF1KB5 VNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPY
                                     : ..:.  .   :..  ::.:..   ..  
XP_011 WPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPISSTAL---AVCV
             50        60        70        80        90            

         200       210       220       230       240       250     
pF1KB5 KLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
       ...:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHI
     100       110       120       130       140       150         

         260       270       280       290       300       310     
pF1KB5 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI
     160       170       180       190       200       210         

         320       330       340       350       360       370     
pF1KB5 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG
     220       230       240       250       260       270         

         380       390       400       410       420       430     
pF1KB5 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ
     280       290       300       310       320       330         

         440       450       460       470       480       490     
pF1KB5 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARA
     340       350       360       370       380       390         

         500    
pF1KB5 FPMPGFDEH
       :::::::::
XP_011 FPMPGFDEH
     400        




504 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:32:23 2016 done: Sat Nov  5 15:32:24 2016
 Total Scan time:  9.170 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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