Result of FASTA (omim) for pF1KB5868
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5868, 493 aa
  1>>>pF1KB5868 493 - 493 aa - 493 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8045+/-0.000498; mu= 12.0952+/- 0.030
 mean_var=167.5880+/-34.368, 0's: 0 Z-trim(114.9): 452  B-trim: 1015 in 1/54
 Lambda= 0.099072
 statistics sampled from 24434 (24976) to 24434 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.293), width:  16
 Scan time:  8.430

The best scores are:                                      opt bits E(85289)
NP_001034437 (OMIM: 126600,601548) EGF-containing  ( 493) 3505 513.7 4.7e-145
NP_001034438 (OMIM: 126600,601548) EGF-containing  ( 493) 3505 513.7 4.7e-145
XP_016859075 (OMIM: 126600,601548) PREDICTED: EGF- ( 413) 1742 261.6   3e-69
XP_005264262 (OMIM: 126600,601548) PREDICTED: EGF- ( 543) 1742 261.8 3.6e-69
NP_058634 (OMIM: 604633,614437) EGF-containing fib ( 443) 1550 234.2 5.8e-61
XP_016876418 (OMIM: 219100,604580,608895,614434) P ( 392) 1304 199.0   2e-50
NP_006320 (OMIM: 219100,604580,608895,614434) fibu ( 448) 1304 199.1 2.2e-50
XP_005267324 (OMIM: 219100,604580,608895,614434) P ( 465) 1304 199.1 2.3e-50
XP_011534660 (OMIM: 219100,604580,608895,614434) P ( 408) 1135 174.9 3.9e-43
XP_011534659 (OMIM: 219100,604580,608895,614434) P ( 464) 1135 174.9 4.3e-43
XP_011534658 (OMIM: 219100,604580,608895,614434) P ( 481) 1135 175.0 4.4e-43
NP_001989 (OMIM: 135821) fibulin-2 isoform b precu (1184)  865 136.8 3.3e-31
NP_001004019 (OMIM: 135821) fibulin-2 isoform a pr (1231)  865 136.8 3.4e-31
NP_001158507 (OMIM: 135821) fibulin-2 isoform a pr (1231)  865 136.8 3.4e-31
NP_001157738 (OMIM: 601216,602090,613097) latent-t (1139)  652 106.3 4.7e-22
NP_066548 (OMIM: 601216,602090,613097) latent-tran (1256)  652 106.4   5e-22
XP_011543335 (OMIM: 601216,602090,613097) PREDICTE (1265)  652 106.4 5.1e-22
NP_001123616 (OMIM: 601216,602090,613097) latent-t (1303)  652 106.4 5.2e-22
XP_011543334 (OMIM: 601216,602090,613097) PREDICTE (1312)  652 106.4 5.2e-22
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861)  632 103.9 6.4e-21
NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 (2912)  632 103.9 6.5e-21
XP_011525689 (OMIM: 604710,613177) PREDICTED: late (1421)  620 101.9 1.3e-20
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436)  620 101.9 1.3e-20
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478)  620 101.9 1.3e-20
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480)  620 101.9 1.3e-20
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522)  620 101.9 1.4e-20
XP_016882842 (OMIM: 604710,613177) PREDICTED: late (1549)  620 101.9 1.4e-20
NP_001036010 (OMIM: 604710,613177) latent-transfor (1557)  620 101.9 1.4e-20
NP_003564 (OMIM: 604710,613177) latent-transformin (1587)  620 101.9 1.4e-20
XP_016882841 (OMIM: 604710,613177) PREDICTED: late (1591)  620 101.9 1.4e-20
XP_011525683 (OMIM: 604710,613177) PREDICTED: late (1593)  620 101.9 1.4e-20
XP_011525681 (OMIM: 604710,613177) PREDICTED: late (1595)  620 101.9 1.4e-20
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611)  620 101.9 1.4e-20
NP_001036009 (OMIM: 604710,613177) latent-transfor (1624)  620 101.9 1.4e-20
XP_011525679 (OMIM: 604710,613177) PREDICTED: late (1635)  620 101.9 1.4e-20
XP_011525678 (OMIM: 604710,613177) PREDICTED: late (1662)  620 101.9 1.5e-20
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871)  621 102.3 1.9e-20
XP_011525684 (OMIM: 604710,613177) PREDICTED: late (1554)  608 100.2 4.6e-20
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438)  607 100.0 4.8e-20
XP_011525682 (OMIM: 604710,613177) PREDICTED: late (1593)  607 100.0 5.1e-20
XP_011531164 (OMIM: 150390) PREDICTED: latent-tran (1248)  585 96.8 3.8e-19
NP_001159738 (OMIM: 150390) latent-transforming gr (1300)  585 96.8 3.9e-19
NP_001159737 (OMIM: 150390) latent-transforming gr (1342)  585 96.8   4e-19
NP_001159736 (OMIM: 150390) latent-transforming gr (1353)  585 96.8 4.1e-19
NP_000618 (OMIM: 150390) latent-transforming growt (1395)  585 96.8 4.1e-19
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639)  586 97.1 4.2e-19
XP_016859597 (OMIM: 150390) PREDICTED: latent-tran (1681)  586 97.1 4.2e-19
XP_011531158 (OMIM: 150390) PREDICTED: latent-tran (1682)  586 97.1 4.2e-19
XP_005264375 (OMIM: 150390) PREDICTED: latent-tran (1626)  585 96.9 4.6e-19
XP_011531163 (OMIM: 150390) PREDICTED: latent-tran (1632)  585 96.9 4.6e-19


>>NP_001034437 (OMIM: 126600,601548) EGF-containing fibu  (493 aa)
 initn: 3505 init1: 3505 opt: 3505  Z-score: 2725.1  bits: 513.7 E(85289): 4.7e-145
Smith-Waterman score: 3505; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)

               10        20        30        40        50        60
pF1KB5 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
              430       440       450       460       470       480

              490   
pF1KB5 VLRLTIIVGPFSF
       :::::::::::::
NP_001 VLRLTIIVGPFSF
              490   

>>NP_001034438 (OMIM: 126600,601548) EGF-containing fibu  (493 aa)
 initn: 3505 init1: 3505 opt: 3505  Z-score: 2725.1  bits: 513.7 E(85289): 4.7e-145
Smith-Waterman score: 3505; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)

               10        20        30        40        50        60
pF1KB5 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
              430       440       450       460       470       480

              490   
pF1KB5 VLRLTIIVGPFSF
       :::::::::::::
NP_001 VLRLTIIVGPFSF
              490   

>>XP_016859075 (OMIM: 126600,601548) PREDICTED: EGF-cont  (413 aa)
 initn: 1603 init1: 1603 opt: 1742  Z-score: 1364.2  bits: 261.6 E(85289): 3e-69
Smith-Waterman score: 2723; 83.8% identity (83.8% similar) in 493 aa overlap (1-493:1-413)

               10        20        30        40        50        60
pF1KB5 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
       ::::::::::::::::::::::::::::::::::::::                      
XP_016 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDEC----------------------
              190       200       210                              

              250       260       270       280       290       300
pF1KB5 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
                                                                 ::
XP_016 ----------------------------------------------------------RT
                                                                220

              310       320       330       340       350       360
pF1KB5 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
              230       240       250       260       270       280

              370       380       390       400       410       420
pF1KB5 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
              290       300       310       320       330       340

              430       440       450       460       470       480
pF1KB5 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
              350       360       370       380       390       400

              490   
pF1KB5 VLRLTIIVGPFSF
       :::::::::::::
XP_016 VLRLTIIVGPFSF
              410   

>>XP_005264262 (OMIM: 126600,601548) PREDICTED: EGF-cont  (543 aa)
 initn: 1603 init1: 1603 opt: 1742  Z-score: 1362.8  bits: 261.8 E(85289): 3.6e-69
Smith-Waterman score: 2723; 83.8% identity (83.8% similar) in 493 aa overlap (1-493:131-543)

                                             10        20        30
pF1KB5                               MLKALFLTMLTLALVKSQDTEETITYTQCT
                                     ::::::::::::::::::::::::::::::
XP_005 SPRCPGPERSAAAQVFLLCCARNSASSRFTMLKALFLTMLTLALVKSQDTEETITYTQCT
              110       120       130       140       150       160

               40        50        60        70        80        90
pF1KB5 DGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQP
              170       180       190       200       210       220

              100       110       120       130       140       150
pF1KB5 AEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIP
              230       240       250       260       270       280

              160       170       180       190       200       210
pF1KB5 SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE
              290       300       310       320       330       340

              220       230       240       250       260       270
pF1KB5 QCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYN
       ::::::::                                                    
XP_005 QCVDIDEC----------------------------------------------------
                                                                   

              280       290       300       310       320       330
pF1KB5 ILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSR
                                   ::::::::::::::::::::::::::::::::
XP_005 ----------------------------RTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSR
                                  350       360       370       380

              340       350       360       370       380       390
pF1KB5 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELP
              390       400       410       420       430       440

              400       410       420       430       440       450
pF1KB5 QSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLV
              450       460       470       480       490       500

              460       470       480       490   
pF1KB5 LVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
       :::::::::::::::::::::::::::::::::::::::::::
XP_005 LVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
              510       520       530       540   

>>NP_058634 (OMIM: 604633,614437) EGF-containing fibulin  (443 aa)
 initn: 1790 init1: 692 opt: 1550  Z-score: 1215.5  bits: 234.2 E(85289): 5.8e-61
Smith-Waterman score: 1793; 50.0% identity (70.6% similar) in 494 aa overlap (1-493:13-443)

                           10        20        30        40        
pF1KB5             MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDEC
                   .: ::.: .:  :  . ::.::  .::.:::::::::  :.:.:..::
NP_058 MLPCASCLPGSLLLWALLLLLLGSA--SPQDSEEPDSYTECTDGYEWDPDSQHCRDVNEC
               10        20          30        40        50        

       50        60        70        80        90       100        
pF1KB5 DIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMA
         .:.:::: :::.::::::::::..: .:  :.                          
NP_058 LTIPEACKGEMKCINHYGGYLCLPRSAAVI--ND--------------------------
       60        70        80          90                          

      110       120       130       140       150       160        
pF1KB5 TSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEH
           : :           ::              :. : . : ::     :  ::: ...
NP_058 ----LHG----------EGPP------------PPVPPAQHP-NP-----CPPGYEPDDQ
                                        100             110        

      170       180       190       200       210       220        
pF1KB5 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRC
       . : :.:::. . :.:: .: : :: ::. : :: ::.: : .:::::::    ::..::
NP_058 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR-YCQHRC
      120       130       140       150       160       170        

      230       240       250       260       270       280        
pF1KB5 VNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSD
       :: :::: ::: :::::. :: .:::.:::: .  : :.:.:  :.:.:.:.:::::  :
NP_058 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRD
       180       190       200       210       220       230       

      290       300       310       320       330       340        
pF1KB5 RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET-TNECRED
        ..: :::::  :::::::.:.::::.::: ::::::.. .: ::::.:::. ...: : 
NP_058 GFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEA
       240       250       260       270       280       290       

       350       360       370       380       390       400       
pF1KB5 EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVP
       . : :.:::.::   : : .::: . ::::.::.:: .::: :.:::..::.: :.::::
NP_058 QTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVP
       300       310       320       330       340       350       

       410       420       430       440       450       460       
pF1KB5 SDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEM
       .:.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..::::...::::
NP_058 ADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEM
       360       370       380       390       400       410       

       470       480       490   
pF1KB5 LTVSSIGTFRTSSVLRLTIIVGPFSF
       .:..:. ..:.:::::::..:: ..:
NP_058 VTMNSLMSYRASSVLRLTVFVGAYTF
       420       430       440   

>>XP_016876418 (OMIM: 219100,604580,608895,614434) PREDI  (392 aa)
 initn: 1290 init1: 534 opt: 1304  Z-score: 1026.1  bits: 199.0 E(85289): 2e-50
Smith-Waterman score: 1304; 48.3% identity (72.0% similar) in 354 aa overlap (144-493:40-392)

           120       130       140       150         160       170 
pF1KB5 PGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNP--SHRIQCAAGYEQSEHNVC
                                     : :   :. :  :. . :  ::...: : :
XP_016 YLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQC
      10        20        30        40        50        60         

             180       190       200       210       220       230 
pF1KB5 QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNT
        :.:::.. .:.:   :.::: .:...:.:  ::     ::.:::::    ::.: :.:.
XP_016 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYG-YCQQLCANV
      70        80        90       100       110        120        

             240       250       260       270       280       290 
pF1KB5 PGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLN
       :::. : :.::: :  .. .: :.::: . : :.: : :  :::::.:. ::::  : ..
XP_016 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVH
      130       140       150       160       170       180        

             300       310       320        330       340          
pF1KB5 CEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE-CREDEM
       : :.:::  : .:::..:::.:: . : :: :: ..  .:.::::::::  :. :  .. 
XP_016 CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQT
      190       200       210       220       230       240        

     350       360       370       380       390       400         
pF1KB5 CWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSD
       :.: .:::.:     :..::.   .:::.::. :  ::. : .:.:. :.. : ::::.:
XP_016 CYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPAD
      250       260       270       280       290       300        

     410       420       430       440       450       460         
pF1KB5 IFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
       :::.:::: : ..   :.::::::. :::.:::.:.:: ::... ..::::  .::::.:
XP_016 IFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMIT
      310       320       330       340       350       360        

     470       480       490   
pF1KB5 VSSIGTFRTSSVLRLTIIVGPFSF
       :... .:: :::.:: : :. . :
XP_016 VNTVINFRGSSVIRLRIYVSQYPF
      370       380       390  

>>NP_006320 (OMIM: 219100,604580,608895,614434) fibulin-  (448 aa)
 initn: 1431 init1: 534 opt: 1304  Z-score: 1025.4  bits: 199.1 E(85289): 2.2e-50
Smith-Waterman score: 1445; 42.8% identity (65.1% similar) in 493 aa overlap (3-493:6-448)

                  10        20        30        40        50       
pF1KB5    MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKG
            . : .:.:.: : .  ...     .:::.:.. :    :: :::::  .:.::.:
NP_006 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRTIPEACRG
               10        20             30        40        50     

        60        70        80        90       100       110       
pF1KB5 GMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGG
        : :::. :::::.:.:  .    . :   ..:               :   ::  :   
NP_006 DMMCVNQNGGYLCIPRTNPVY---RGPY--SNPY--------------STPYSGPYP---
          60        70           80                        90      

       120       130       140       150       160       170       
pF1KB5 FVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDEC
         :.:  ...:.. :      : :    :          . :  ::...: : : :.:::
NP_006 --AAAPPLSAPNYPT------ISR----P----------LICRFGYQMDESNQCVDVDEC
             100                 110                 120       130 

       180       190       200       210       220       230       
pF1KB5 TAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYC
       .. .:.:   :.::: .:...:.:  ::     ::.:::::    ::.: :.:.:::. :
NP_006 ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYG-YCQQLCANVPGSYSC
             140       150       160       170        180       190

       240       250       260       270       280       290       
pF1KB5 QCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDE
        :.::: :  .. .: :.::: . : :.: : :  :::::.:. ::::  : ..: :.::
NP_006 TCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDE
              200       210       220       230       240       250

       300       310       320        330       340        350     
pF1KB5 CRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE-CREDEMCWNYHG
       :  : .:::..:::.:: . : :: :: ..  .:.::::::::  :. :  .. :.: .:
NP_006 CSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQG
              260       270       280       290       300       310

         360       370       380       390       400       410     
pF1KB5 GFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQA
       ::.:     :..::.   .:::.::. :  ::. : .:.:. :.. : ::::.::::.::
NP_006 GFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQA
              320       330       340       350       360       370

         420       430       440       450       460       470     
pF1KB5 TTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGT
       :: : ..   :.::::::. :::.:::.:.:: ::... ..::::  .::::.::... .
NP_006 TTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMITVNTVIN
              380       390       400       410       420       430

         480       490   
pF1KB5 FRTSSVLRLTIIVGPFSF
       :: :::.:: : :. . :
NP_006 FRGSSVIRLRIYVSQYPF
              440        

>>XP_005267324 (OMIM: 219100,604580,608895,614434) PREDI  (465 aa)
 initn: 1431 init1: 534 opt: 1304  Z-score: 1025.2  bits: 199.1 E(85289): 2.3e-50
Smith-Waterman score: 1443; 43.0% identity (65.2% similar) in 491 aa overlap (5-493:25-465)

                                   10        20        30        40
pF1KB5                     MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQ
                               : .:.:.: : .  ...     .:::.:.. :    
XP_005 MFVWDSHRSFKPMRSGNCRQRYMILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSG
               10        20        30        40             50     

               50        60        70        80        90       100
pF1KB5 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG
       :: :::::  .:.::.: : :::. :::::.:.:  .    . :   ..:          
XP_005 QCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVY---RGPY--SNPY---------
          60        70        80        90            100          

              110       120       130       140       150       160
pF1KB5 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA
            :   ::  :     :.:  ...:.. :      : : :             . : 
XP_005 -----STPYSGPYP-----AAAPPLSAPNYPT------ISR-P-------------LICR
                  110            120                           130 

              170       180       190       200       210       220
pF1KB5 AGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTI
        ::...: : : :.:::.. .:.:   :.::: .:...:.:  ::     ::.:::::  
XP_005 FGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRY
             140       150       160       170       180       190 

              230       240       250       260       270       280
pF1KB5 PPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCN
         ::.: :.:.:::. : :.::: :  .. .: :.::: . : :.: : :  :::::.:.
XP_005 G-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCD
              200       210       220       230       240       250

              290       300       310       320        330         
pF1KB5 QGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECE
        ::::  : ..: :.:::  : .:::..:::.:: . : :: :: ..  .:.::::::::
XP_005 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE
              260       270       280       290       300       310

     340        350       360       370       380       390        
pF1KB5 TTNE-CREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYM
         :. :  .. :.: .:::.:     :..::.   .:::.::. :  ::. : .:.:. :
XP_005 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDM
              320       330       340       350       360       370

      400       410       420       430       440       450        
pF1KB5 SIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGP
       .. : ::::.::::.:::: : ..   :.::::::. :::.:::.:.:: ::... ..::
XP_005 DVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGP
              380       390       400       410       420       430

      460       470       480       490   
pF1KB5 REHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
       ::  .::::.::... .:: :::.:: : :. . :
XP_005 REIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
              440       450       460     

>>XP_011534660 (OMIM: 219100,604580,608895,614434) PREDI  (408 aa)
 initn: 1121 init1: 478 opt: 1135  Z-score: 895.4  bits: 174.9 E(85289): 3.9e-43
Smith-Waterman score: 1135; 46.4% identity (70.3% similar) in 317 aa overlap (144-456:40-355)

           120       130       140       150         160       170 
pF1KB5 PGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNP--SHRIQCAAGYEQSEHNVC
                                     : :   :. :  :. . :  ::...: : :
XP_011 YLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQC
      10        20        30        40        50        60         

             180       190       200       210       220       230 
pF1KB5 QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNT
        :.:::.. .:.:   :.::: .:...:.:  ::     ::.:::::    ::.: :.:.
XP_011 VDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYG-YCQQLCANV
      70        80        90       100       110        120        

             240       250       260       270       280       290 
pF1KB5 PGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLN
       :::. : :.::: :  .. .: :.::: . : :.: : :  :::::.:. ::::  : ..
XP_011 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVH
      130       140       150       160       170       180        

             300       310       320        330       340          
pF1KB5 CEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE-CREDEM
       : :.:::  : .:::..:::.:: . : :: :: ..  .:.::::::::  :. :  .. 
XP_011 CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQT
      190       200       210       220       230       240        

     350       360       370       380       390       400         
pF1KB5 CWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSD
       :.: .:::.:     :..::.   .:::.::. :  ::. : .:.:. :.. : ::::.:
XP_011 CYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPAD
      250       260       270       280       290       300        

     410       420       430       440       450       460         
pF1KB5 IFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
       :::.:::: : ..   :.::::::. :::.:..  ..:. .  ..::             
XP_011 IFQMQATTRYPGAYYIFQIKSGNEGREFYMRRAFSTTAYEASSQALSVEKQTGCGLCPGG
      310       320       330       340       350       360        

     470       480       490                   
pF1KB5 VSSIGTFRTSSVLRLTIIVGPFSF                
                                               
XP_011 THTHLSGEGENNLANTTQSGDSQVKSRPMGCKRAPSVPPW
      370       380       390       400        

>>XP_011534659 (OMIM: 219100,604580,608895,614434) PREDI  (464 aa)
 initn: 1262 init1: 478 opt: 1135  Z-score: 894.7  bits: 174.9 E(85289): 4.3e-43
Smith-Waterman score: 1276; 41.0% identity (63.4% similar) in 456 aa overlap (3-456:6-411)

                  10        20        30        40        50       
pF1KB5    MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKG
            . : .:.:.: : .  ...     .:::.:.. :    :: :::::  .:.::.:
XP_011 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRTIPEACRG
               10        20             30        40        50     

        60        70        80        90       100       110       
pF1KB5 GMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGG
        : :::. :::::.:.:  .    . :   ..:               :   ::  :   
XP_011 DMMCVNQNGGYLCIPRTNPVY---RGPY--SNPY--------------STPYSGPYP---
          60        70           80                        90      

       120       130       140       150       160       170       
pF1KB5 FVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDEC
         :.:  ...:.. :      : : :             . :  ::...: : : :.:::
XP_011 --AAAPPLSAPNYPT------ISR-P-------------LICRFGYQMDESNQCVDVDEC
             100              110                    120       130 

       180       190       200       210       220       230       
pF1KB5 TAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYC
       .. .:.:   :.::: .:...:.:  ::     ::.:::::    ::.: :.:.:::. :
XP_011 ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYG-YCQQLCANVPGSYSC
             140       150       160       170        180       190

       240       250       260       270       280       290       
pF1KB5 QCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDE
        :.::: :  .. .: :.::: . : :.: : :  :::::.:. ::::  : ..: :.::
XP_011 TCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDE
              200       210       220       230       240       250

       300       310       320        330       340        350     
pF1KB5 CRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE-CREDEMCWNYHG
       :  : .:::..:::.:: . : :: :: ..  .:.::::::::  :. :  .. :.: .:
XP_011 CSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQG
              260       270       280       290       300       310

         360       370       380       390       400       410     
pF1KB5 GFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQA
       ::.:     :..::.   .:::.::. :  ::. : .:.:. :.. : ::::.::::.::
XP_011 GFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQA
              320       330       340       350       360       370

         420       430       440       450       460       470     
pF1KB5 TTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGT
       :: : ..   :.::::::. :::.:..  ..:. .  ..::                   
XP_011 TTRYPGAYYIFQIKSGNEGREFYMRRAFSTTAYEASSQALSVEKQTGCGLCPGGTHTHLS
              380       390       400       410       420       430

         480       490                   
pF1KB5 FRTSSVLRLTIIVGPFSF                
                                         
XP_011 GEGENNLANTTQSGDSQVKSRPMGCKRAPSVPPW
              440       450       460    




493 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:22:55 2016 done: Sat Nov  5 15:22:56 2016
 Total Scan time:  8.430 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com