Result of FASTA (omim) for pF1KB7937
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7937, 376 aa
  1>>>pF1KB7937 376 - 376 aa - 376 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.7131+/-0.000436; mu= -6.8019+/- 0.027
 mean_var=342.5732+/-72.708, 0's: 0 Z-trim(121.2): 108  B-trim: 349 in 1/56
 Lambda= 0.069294
 statistics sampled from 37302 (37421) to 37302 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.439), width:  16
 Scan time:  8.080

The best scores are:                                      opt bits E(85289)
NP_056943 (OMIM: 600520) transcription initiation  ( 376) 2492 262.6 1.1e-69
NP_963889 (OMIM: 600520) transcription initiation  ( 337) 2246 238.0 2.5e-62
NP_001265869 (OMIM: 600520) transcription initiati ( 326) 2173 230.6 3.9e-60
NP_001180416 (OMIM: 605358) TFIIA-alpha and beta-l ( 444)  412 54.7 4.8e-07
NP_006863 (OMIM: 605358) TFIIA-alpha and beta-like ( 478)  412 54.7 5.1e-07


>>NP_056943 (OMIM: 600520) transcription initiation fact  (376 aa)
 initn: 2492 init1: 2492 opt: 2492  Z-score: 1372.2  bits: 262.6 E(85289): 1.1e-69
Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376)

               10        20        30        40        50        60
pF1KB7 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 SEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL
              310       320       330       340       350       360

              370      
pF1KB7 NGRDYIFSKAIGDAEW
       ::::::::::::::::
NP_056 NGRDYIFSKAIGDAEW
              370      

>>NP_963889 (OMIM: 600520) transcription initiation fact  (337 aa)
 initn: 2246 init1: 2246 opt: 2246  Z-score: 1239.9  bits: 238.0 E(85289): 2.5e-62
Smith-Waterman score: 2246; 100.0% identity (100.0% similar) in 337 aa overlap (40-376:1-337)

      10        20        30        40        50        60         
pF1KB7 VPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQ
                                     ::::::::::::::::::::::::::::::
NP_963                               MELKTLWENKLMQSRAVDGFHSEEQQLLLQ
                                             10        20        30

      70        80        90       100       110       120         
pF1KB7 VQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHM
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KB7 NASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVI
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KB7 PQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQ
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KB7 ITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQV
              220       230       240       250       260       270

     310       320       330       340       350       360         
pF1KB7 EEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSK
              280       290       300       310       320       330

     370      
pF1KB7 AIGDAEW
       :::::::
NP_963 AIGDAEW
              

>>NP_001265869 (OMIM: 600520) transcription initiation f  (326 aa)
 initn: 2173 init1: 2173 opt: 2173  Z-score: 1200.6  bits: 230.6 E(85289): 3.9e-60
Smith-Waterman score: 2173; 100.0% identity (100.0% similar) in 326 aa overlap (51-376:1-326)

               30        40        50        60        70        80
pF1KB7 VINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MQSRAVDGFHSEEQQLLLQVQQQHQPQQQQ
                                             10        20        30

               90       100       110       120       130       140
pF1KB7 HHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATA
               40        50        60        70        80        90

              150       160       170       180       190       200
pF1KB7 ATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAP
              100       110       120       130       140       150

              210       220       230       240       250       260
pF1KB7 VIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQA
              160       170       180       190       200       210

              270       280       290       300       310       320
pF1KB7 QPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDV
              220       230       240       250       260       270

              330       340       350       360       370      
pF1KB7 SDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
              280       290       300       310       320      

>>NP_001180416 (OMIM: 605358) TFIIA-alpha and beta-like   (444 aa)
 initn: 501 init1: 403 opt: 412  Z-score: 247.4  bits: 54.7 E(85289): 4.8e-07
Smith-Waterman score: 451; 34.6% identity (58.4% similar) in 332 aa overlap (97-376:120-444)

         70        80        90       100       110       120      
pF1KB7 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI
                                     : :   ::.  :.  :...:: . : : : 
NP_001 TLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQ-LNPWS-LQ
      90       100       110       120       130       140         

        130       140       150                160            170  
pF1KB7 QHMNASNMSAAATAATLALPAGVTPVQQ---------ILTNSGQLLQVVRAA-----NGA
          . :.   ..      ::.:  ::..         ::.. :.  ..:  :     ...
NP_001 ATTEKSQRIETVLQQPAILPSG--PVDRKHLENATSDILVSPGNEHKIVPEALLCHQESS
       150       160         170       180       190       200     

            180             190       200         210         220  
pF1KB7 QYIFQPQQSVVLQQQV------IPQMQPGGVQAP--VIQQVLAPLPGGISPQ--TGVIIQ
       .::  :  .::.. ::      . ..  :...    . .. :.  : :   :  : . ..
NP_001 HYISLP--GVVFSPQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLH
         210         220       230       240       250       260   

            230       240         250       260       270       280
pF1KB7 PQQILFTGNKTQVIPTTVAAPT--PAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTS
         .  . :  .   : ..  :.  :.. .  ...: . . . .. .   ..::::.::::
NP_001 ILKNRMYGCDSVKQPRNIEEPSNIPVSEK-DSNSQVDLSIRVTDDDIGEIIQVDGSGDTS
           270       280       290        300       310       320  

                         290             300                310    
pF1KB7 SEE------DEDEEE-----DYDD----DEEEDK--EKDGA------EDGQV---EEEPL
       :.:      : ::.:     :  :    .:: :.  ..:.:      :: ::   ::.::
NP_001 SNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNEDPQVNIVEEDPL
            330       340       350       360       370       380  

          320       330       340       350       360       370    
pF1KB7 NSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDA
       :: ::::...  .::::.::.::::::::::::::::.::::.: ..::::.:.::::::
NP_001 NSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRDYVFAKAIGDA
            390       400       410       420       430       440  

         
pF1KB7 EW
       ::
NP_001 EW
         

>>NP_006863 (OMIM: 605358) TFIIA-alpha and beta-like fac  (478 aa)
 initn: 653 init1: 403 opt: 412  Z-score: 247.0  bits: 54.7 E(85289): 5.1e-07
Smith-Waterman score: 451; 34.6% identity (58.4% similar) in 332 aa overlap (97-376:154-478)

         70        80        90       100       110       120      
pF1KB7 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI
                                     : :   ::.  :.  :...:: . : : : 
NP_006 TLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQ-LNPWS-LQ
           130       140       150       160       170         180 

        130       140       150                160            170  
pF1KB7 QHMNASNMSAAATAATLALPAGVTPVQQ---------ILTNSGQLLQVVRAA-----NGA
          . :.   ..      ::.:  ::..         ::.. :.  ..:  :     ...
NP_006 ATTEKSQRIETVLQQPAILPSG--PVDRKHLENATSDILVSPGNEHKIVPEALLCHQESS
             190       200         210       220       230         

            180             190       200         210         220  
pF1KB7 QYIFQPQQSVVLQQQV------IPQMQPGGVQAP--VIQQVLAPLPGGISPQ--TGVIIQ
       .::  :  .::.. ::      . ..  :...    . .. :.  : :   :  : . ..
NP_006 HYISLP--GVVFSPQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLH
     240         250       260       270       280       290       

            230       240         250       260       270       280
pF1KB7 PQQILFTGNKTQVIPTTVAAPT--PAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTS
         .  . :  .   : ..  :.  :.. .  ...: . . . .. .   ..::::.::::
NP_006 ILKNRMYGCDSVKQPRNIEEPSNIPVSEK-DSNSQVDLSIRVTDDDIGEIIQVDGSGDTS
       300       310       320        330       340       350      

                         290             300                310    
pF1KB7 SEE------DEDEEE-----DYDD----DEEEDK--EKDGA------EDGQV---EEEPL
       :.:      : ::.:     :  :    .:: :.  ..:.:      :: ::   ::.::
NP_006 SNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNEDPQVNIVEEDPL
        360       370       380       390       400       410      

          320       330       340       350       360       370    
pF1KB7 NSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDA
       :: ::::...  .::::.::.::::::::::::::::.::::.: ..::::.:.::::::
NP_006 NSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRDYVFAKAIGDA
        420       430       440       450       460       470      

         
pF1KB7 EW
       ::
NP_006 EW
         




376 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 14:40:47 2016 done: Sat Nov  5 14:40:49 2016
 Total Scan time:  8.080 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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