Result of FASTA (omim) for pF1KB6268
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6268, 772 aa
  1>>>pF1KB6268 772 - 772 aa - 772 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2911+/-0.000425; mu= 2.5279+/- 0.027
 mean_var=223.4613+/-44.766, 0's: 0 Z-trim(118.6): 22  B-trim: 428 in 1/53
 Lambda= 0.085797
 statistics sampled from 31743 (31766) to 31743 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.372), width:  16
 Scan time: 13.810

The best scores are:                                      opt bits E(85289)
NP_003189 (OMIM: 600786) transcription elongation  ( 798) 5156 651.7 3.5e-186
NP_057511 (OMIM: 609522) RNA polymerase II transcr ( 753) 1551 205.5   7e-52


>>NP_003189 (OMIM: 600786) transcription elongation fact  (798 aa)
 initn: 5156 init1: 5156 opt: 5156  Z-score: 3463.6  bits: 651.7 E(85289): 3.5e-186
Smith-Waterman score: 5156; 100.0% identity (100.0% similar) in 772 aa overlap (1-772:27-798)

                                         10        20        30    
pF1KB6                           MAAESALQVVEKLQARLAANPDPKKLLKYLKKLS
                                 ::::::::::::::::::::::::::::::::::
NP_003 MHGGRSCGPRTRREPSSGEEAAPVTAMAAESALQVVEKLQARLAANPDPKKLLKYLKKLS
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB6 TLPITVDILAETGVGKTVNSLRKHEHVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLPITVDILAETGVGKTVNSLRKHEHVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNS
               70        80        90       100       110       120

          100       110       120       130       140       150    
pF1KB6 RKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDE
              130       140       150       160       170       180

          160       170       180       190       200       210    
pF1KB6 RKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGH
              190       200       210       220       230       240

          220       230       240       250       260       270    
pF1KB6 SNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKA
              250       260       270       280       290       300

          280       290       300       310       320       330    
pF1KB6 LSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPE
              310       320       330       340       350       360

          340       350       360       370       380       390    
pF1KB6 KAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSLPKVEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSLPKVEET
              370       380       390       400       410       420

          400       410       420       430       440       450    
pF1KB6 DMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKL
              430       440       450       460       470       480

          460       470       480       490       500       510    
pF1KB6 PKVNKTKSEKPAGADLAKLRKVPDVLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKVNKTKSEKPAGADLAKLRKVPDVLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAF
              490       500       510       520       530       540

          520       530       540       550       560       570    
pF1KB6 SSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPY
              550       560       570       580       590       600

          580       590       600       610       620       630    
pF1KB6 SVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQ
              610       620       630       640       650       660

          640       650       660       670       680       690    
pF1KB6 DAREQRLRVLTKNIQFAHANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DAREQRLRVLTKNIQFAHANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKI
              670       680       690       700       710       720

          700       710       720       730       740       750    
pF1KB6 KIKPAPYPMGSSHASASSISFNPSPEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KIKPAPYPMGSSHASASSISFNPSPEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKI
              730       740       750       760       770       780

          760       770  
pF1KB6 APMMAKTIKAFKNRFSRR
       ::::::::::::::::::
NP_003 APMMAKTIKAFKNRFSRR
              790        

>>NP_057511 (OMIM: 609522) RNA polymerase II transcripti  (753 aa)
 initn: 1853 init1: 674 opt: 1551  Z-score: 1052.4  bits: 205.5 E(85289): 7e-52
Smith-Waterman score: 2087; 47.7% identity (71.0% similar) in 791 aa overlap (1-772:1-753)

                10        20        30        40        50         
pF1KB6 MAAESA-LQVVEKLQARLAANPDPKKLLKYLKKLSTLPITVDILAETGVGKTVNSLRKHE
       ::: :. :..:::::.:::.. .:::: :::.:::.::.:.:::::::. :::. ::::.
NP_057 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB6 HVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKAT
       :::.:::::.:.::::: :.::..:  :: :.: ::.:  .::: .:.  : . :.  : 
NP_057 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWG-FPENATAP
               70        80        90       100       110          

     120       130       140       150       160       170         
pF1KB6 GSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQS
        : :.::.::.  .:     .:::  ::..: : ::: : :..:        .: :. ..
NP_057 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERK-CPRIAP--------ADSGRYRA
     120       130       140       150        160               170

     180       190       200       210       220         230       
pF1KB6 PPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQ--ERHLGEPHGKG
        :. :.: .:         :  :: .  ..::.::..: :   :.        :.:.::.
NP_057 SPTRTAPLRM--------PEGPEPAAPGKQPGRGHTHAAQ---GGPLLCPGCQGQPQGKA
              180               190       200          210         

       240       250       260       270       280       290       
pF1KB6 VVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSS-
       :::..: ::::...:::. :..: .. .. ::::  :  .::. : ::  .::.. ::. 
NP_057 VVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDF
     220       230       240       250       260       270         

        300       310       320       330       340       350      
pF1KB6 GVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGD
        . ::  . ::. .   .:  : : :.: :.:.:     .. .:.. .::. : :.:.  
NP_057 KTDKEGGQAGSGQR---VPALEEAPDSHQKRPQH-----SHSNKKRPSLDGRDPGNGTHG
     280       290          300       310            320       330 

        360       370        380       390       400       410     
pF1KB6 LLPKVKEKGSNNLKTPEGKVKT-NLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQ
       : :. ::. ::. .: :::  : .::: :..:: .:::.:: .::::::.: :.::.:::
NP_057 LSPEEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQ
             340       350       360       370       380       390 

         420       430       440       450       460         470   
pF1KB6 PRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKLPKVNKTKSEK--PAGADLAKL
        ::.:::  :...::::::  : :.::.: .. ::..::: :....::.   :::: :  
NP_057 LRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQSERLQAAGADSAGP
             400       410       420       430       440       450 

            480       490       500       510       520       530  
pF1KB6 RKVPD-VLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAFSSPQEEEEAGFTGRRMNS
       . ::. :.  : ::    .:::: :: . . ..: : : .:.:::. .:::.: :::.:.
NP_057 KTVPSHVFSELWDLSEAWMQANYDPLSDSDSMTS-QAKPEALSSPKFREEAAFPGRRVNA
             460       470       480        490       500       510

            540       550       560       570       580       590  
pF1KB6 KMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRI
       :: :::::. :   .. ::.::: .::.:: :.. .:: ::: :::::::   :::::: 
NP_057 KMPVYSGSRPACQLQVPTLRQQCAQVLRNNPDALSDVGEVPYWVLEPVLEGWRPDQLYRR
              520       530       540       550       560       570

            600       610       620       630       640       650  
pF1KB6 EEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAH
       .. ::.:..:::.: . :: .:::::.:.: ..:::.:::: :: ::::::.: ::. :.
NP_057 KKDNHALVRETDELRRNHCFQDFKEEKPQENKTWREQYLRLPDAPEQRLRVMTTNIRSAR
              580       590       600       610       620       630

            660       670       680       690       700       710  
pF1KB6 ANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASASS
       .:.:.::.:::   .:::: : :. :::::  ..: : ::. .::::  : ::::. .:.
NP_057 GNNPNGREAKMICFKSVAKTPYDTSRRQEK--SAGDADPENGEIKPASKPAGSSHTPSSQ
              640       650       660         670       680        

                       720       730       740       750       760 
pF1KB6 ISFNPS-----------PEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKT
        : . .           ::. :    :.:. : ::....      :: ..::.::.:::.
NP_057 SSSGGGRDSSSSILRWLPEKRANPCLSSSNEHAAPAAKT------RKQAAKKVAPLMAKA
      690       700       710       720             730       740  

             770  
pF1KB6 IKAFKNRFSRR
       :. .: :::::
NP_057 IRDYKRRFSRR
            750   




772 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:59:12 2016 done: Sat Nov  5 13:59:14 2016
 Total Scan time: 13.810 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com