Result of FASTA (omim) for pF1KB6174
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6174, 630 aa
  1>>>pF1KB6174 630 - 630 aa - 630 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.1246+/-0.000314; mu= 4.7398+/- 0.020
 mean_var=247.7124+/-49.434, 0's: 0 Z-trim(124.7): 103  B-trim: 0 in 0/60
 Lambda= 0.081489
 statistics sampled from 46649 (46760) to 46649 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.548), width:  16
 Scan time: 13.920

The best scores are:                                      opt bits E(85289)
NP_001191066 (OMIM: 156535) methyl-CpG-binding dom ( 630) 4561 549.0 1.8e-155
XP_011524295 (OMIM: 156535) PREDICTED: methyl-CpG- ( 630) 4561 549.0 1.8e-155
XP_011524296 (OMIM: 156535) PREDICTED: methyl-CpG- ( 630) 4561 549.0 1.8e-155
NP_001191067 (OMIM: 156535) methyl-CpG-binding dom ( 629) 4543 546.9 7.8e-155
XP_006722519 (OMIM: 156535) PREDICTED: methyl-CpG- ( 662) 4483 539.9 1.1e-152
NP_001310871 (OMIM: 156535) methyl-CpG-binding dom ( 680) 4475 539.0 2.1e-152
XP_016881240 (OMIM: 156535) PREDICTED: methyl-CpG- ( 647) 3748 453.5 1.1e-126
XP_016881247 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 3746 453.2 1.2e-126
XP_016881246 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 3746 453.2 1.2e-126
XP_016881248 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 3746 453.2 1.2e-126
XP_016881243 (OMIM: 156535) PREDICTED: methyl-CpG- ( 627) 3746 453.2 1.2e-126
NP_001310876 (OMIM: 156535) methyl-CpG-binding dom ( 665) 3746 453.2 1.3e-126
XP_011524305 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 3744 453.0 1.4e-126
XP_011524304 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 3744 453.0 1.4e-126
XP_016881253 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 3744 453.0 1.4e-126
XP_016881250 (OMIM: 156535) PREDICTED: methyl-CpG- ( 596) 3744 453.0 1.4e-126
XP_016881245 (OMIM: 156535) PREDICTED: methyl-CpG- ( 616) 3744 453.0 1.4e-126
XP_011524293 (OMIM: 156535) PREDICTED: methyl-CpG- ( 634) 3744 453.0 1.5e-126
NP_001310878 (OMIM: 156535) methyl-CpG-binding dom ( 461) 3364 408.2 3.3e-113
XP_016881255 (OMIM: 156535) PREDICTED: methyl-CpG- ( 574) 2592 317.5 8.1e-86
XP_016881256 (OMIM: 156535) PREDICTED: methyl-CpG- ( 574) 2592 317.5 8.1e-86
NP_001191069 (OMIM: 156535) methyl-CpG-binding dom ( 574) 2592 317.5 8.1e-86
NP_056723 (OMIM: 156535) methyl-CpG-binding domain ( 556) 2459 301.9   4e-81
NP_056671 (OMIM: 156535) methyl-CpG-binding domain ( 605) 2452 301.1 7.6e-81
XP_016881249 (OMIM: 156535) PREDICTED: methyl-CpG- ( 605) 2452 301.1 7.6e-81
NP_001191068 (OMIM: 156535) methyl-CpG-binding dom ( 605) 2452 301.1 7.6e-81
XP_005258328 (OMIM: 156535) PREDICTED: methyl-CpG- ( 605) 2452 301.1 7.6e-81
XP_016881242 (OMIM: 156535) PREDICTED: methyl-CpG- ( 637) 2374 291.9 4.5e-78
XP_016881244 (OMIM: 156535) PREDICTED: methyl-CpG- ( 617) 2373 291.8 4.8e-78
NP_001191065 (OMIM: 156535) methyl-CpG-binding dom ( 655) 2366 291.0 8.9e-78
NP_001191070 (OMIM: 156535) methyl-CpG-binding dom ( 567) 2361 290.4 1.2e-77
XP_016881262 (OMIM: 156535) PREDICTED: methyl-CpG- ( 526) 1974 244.8 5.6e-64
XP_016881263 (OMIM: 156535) PREDICTED: methyl-CpG- ( 526) 1974 244.8 5.6e-64
NP_001310883 (OMIM: 156535) methyl-CpG-binding dom ( 576) 1974 244.9   6e-64
NP_002375 (OMIM: 156535) methyl-CpG-binding domain ( 503) 1969 244.2 8.2e-64
XP_016881265 (OMIM: 156535) PREDICTED: methyl-CpG- ( 503) 1969 244.2 8.2e-64
XP_016881264 (OMIM: 156535) PREDICTED: methyl-CpG- ( 515) 1969 244.2 8.3e-64
XP_011524308 (OMIM: 156535) PREDICTED: methyl-CpG- ( 535) 1969 244.2 8.6e-64
NP_001191072 (OMIM: 156535) methyl-CpG-binding dom ( 535) 1969 244.2 8.6e-64
XP_016881261 (OMIM: 156535) PREDICTED: methyl-CpG- ( 546) 1969 244.3 8.7e-64
NP_056669 (OMIM: 156535) methyl-CpG-binding domain ( 549) 1969 244.3 8.7e-64
XP_016881260 (OMIM: 156535) PREDICTED: methyl-CpG- ( 549) 1969 244.3 8.7e-64
XP_016881259 (OMIM: 156535) PREDICTED: methyl-CpG- ( 549) 1969 244.3 8.7e-64
NP_001191071 (OMIM: 156535) methyl-CpG-binding dom ( 550) 1969 244.3 8.7e-64
XP_011524309 (OMIM: 156535) PREDICTED: methyl-CpG- ( 559) 1969 244.3 8.8e-64
XP_016881258 (OMIM: 156535) PREDICTED: methyl-CpG- ( 559) 1969 244.3 8.8e-64
XP_016881257 (OMIM: 156535) PREDICTED: methyl-CpG- ( 561) 1969 244.3 8.9e-64
XP_016881266 (OMIM: 156535) PREDICTED: methyl-CpG- ( 571) 1969 244.3   9e-64
XP_016881254 (OMIM: 156535) PREDICTED: methyl-CpG- ( 581) 1969 244.3 9.1e-64
XP_016881252 (OMIM: 156535) PREDICTED: methyl-CpG- ( 589) 1969 244.3 9.2e-64


>>NP_001191066 (OMIM: 156535) methyl-CpG-binding domain   (630 aa)
 initn: 4561 init1: 4561 opt: 4561  Z-score: 2912.2  bits: 549.0 E(85289): 1.8e-155
Smith-Waterman score: 4561; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
              550       560       570       580       590       600

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
NP_001 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
              610       620       630

>>XP_011524295 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (630 aa)
 initn: 4561 init1: 4561 opt: 4561  Z-score: 2912.2  bits: 549.0 E(85289): 1.8e-155
Smith-Waterman score: 4561; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
              550       560       570       580       590       600

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
XP_011 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
              610       620       630

>>XP_011524296 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (630 aa)
 initn: 4561 init1: 4561 opt: 4561  Z-score: 2912.2  bits: 549.0 E(85289): 1.8e-155
Smith-Waterman score: 4561; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
              550       560       570       580       590       600

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
XP_011 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
              610       620       630

>>NP_001191067 (OMIM: 156535) methyl-CpG-binding domain   (629 aa)
 initn: 3081 init1: 3081 opt: 4543  Z-score: 2900.8  bits: 546.9 E(85289): 7.8e-155
Smith-Waterman score: 4543; 99.8% identity (99.8% similar) in 630 aa overlap (1-630:1-629)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAM-RLLPSVWSESED
              370       380       390       400        410         

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
     540       550       560       570       580       590         

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
NP_001 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
     600       610       620         

>>XP_006722519 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (662 aa)
 initn: 4690 init1: 4483 opt: 4483  Z-score: 2862.4  bits: 539.9 E(85289): 1.1e-152
Smith-Waterman score: 4483; 99.8% identity (100.0% similar) in 619 aa overlap (1-619:1-619)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
              550       560       570       580       590       600

              610       620       630                              
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ                              
       ::::::::::::::::::.                                         
XP_006 IFSLGGTRFRDTAVWLPRAGTREGKMDVKCGRPRTQWSPRARAGTHEDGLEPMSVSHHLQ
              610       620       630       640       650       660

>>NP_001310871 (OMIM: 156535) methyl-CpG-binding domain   (680 aa)
 initn: 4475 init1: 4475 opt: 4475  Z-score: 2857.1  bits: 539.0 E(85289): 2.1e-152
Smith-Waterman score: 4475; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
              550       560       570       580       590       600

              610       620       630                              
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ                              
       :::::::::::::::::                                           
NP_001 IFSLGGTRFRDTAVWLPSLQGRHSGREDGCKVWETEDTVEPTSTSWNPRGWPGTHVSLSP
              610       620       630       640       650       660

>>XP_016881240 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (647 aa)
 initn: 4379 init1: 3725 opt: 3748  Z-score: 2395.5  bits: 453.5 E(85289): 1.1e-126
Smith-Waterman score: 4337; 97.4% identity (97.6% similar) in 619 aa overlap (1-619:1-604)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       ::::::::::::::::::::::::::               :::::::::::::::::::
XP_016 LVFLREGASSPVQVPGPVAASTEALL---------------QVKQEKADTQDEWTPGTAV
              490       500                      510       520     

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
         530       540       550       560       570       580     

              610       620       630                              
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ                              
       ::::::::::::::::::.                                         
XP_016 IFSLGGTRFRDTAVWLPRAGTREGKMDVKCGRPRTQWSPRARAGTHEDGLEPMSVSHHLQ
         590       600       610       620       630       640     

>>XP_016881247 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (615 aa)
 initn: 3725 init1: 3725 opt: 3746  Z-score: 2394.5  bits: 453.2 E(85289): 1.2e-126
Smith-Waterman score: 4415; 97.6% identity (97.6% similar) in 630 aa overlap (1-630:1-615)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       :::::::::::::::::::::::::::               ::::::::::::::::::
XP_016 LVFLREGASSPVQVPGPVAASTEALLQ---------------VKQEKADTQDEWTPGTAV
              490       500                      510       520     

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
         530       540       550       560       570       580     

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
XP_016 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
         590       600       610     

>>XP_016881246 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (615 aa)
 initn: 3725 init1: 3725 opt: 3746  Z-score: 2394.5  bits: 453.2 E(85289): 1.2e-126
Smith-Waterman score: 4415; 97.6% identity (97.6% similar) in 630 aa overlap (1-630:1-615)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       :::::::::::::::::::::::::::               ::::::::::::::::::
XP_016 LVFLREGASSPVQVPGPVAASTEALLQ---------------VKQEKADTQDEWTPGTAV
              490       500                      510       520     

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
         530       540       550       560       570       580     

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
XP_016 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
         590       600       610     

>>XP_016881248 (OMIM: 156535) PREDICTED: methyl-CpG-bind  (615 aa)
 initn: 3725 init1: 3725 opt: 3746  Z-score: 2394.5  bits: 453.2 E(85289): 1.2e-126
Smith-Waterman score: 4415; 97.6% identity (97.6% similar) in 630 aa overlap (1-630:1-615)

               10        20        30        40        50        60
pF1KB6 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PICLRPPRPGLRRQWKCVQRRCLRHLAHRLRRRHQRCQRRTPLAVAPPTGKHARRKGGCD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAV
       :::::::::::::::::::::::::::               ::::::::::::::::::
XP_016 LVFLREGASSPVQVPGPVAASTEALLQ---------------VKQEKADTQDEWTPGTAV
              490       500                      510       520     

              550       560       570       580       590       600
pF1KB6 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITE
         530       540       550       560       570       580     

              610       620       630
pF1KB6 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
       ::::::::::::::::::::::::::::::
XP_016 IFSLGGTRFRDTAVWLPRSKDLKKPGARKQ
         590       600       610     




630 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:41:39 2016 done: Sat Nov  5 13:41:41 2016
 Total Scan time: 13.920 Total Display time:  0.170

Function used was FASTA [36.3.4 Apr, 2011]
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