Result of FASTA (omim) for pF1KB5289
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5289, 418 aa
  1>>>pF1KB5289 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5066+/-0.000346; mu= 16.9489+/- 0.022
 mean_var=71.6530+/-14.510, 0's: 0 Z-trim(115.1): 126  B-trim: 800 in 1/58
 Lambda= 0.151515
 statistics sampled from 25181 (25326) to 25181 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.297), width:  16
 Scan time:  9.610

The best scores are:                                      opt bits E(85289)
NP_002606 (OMIM: 172860,613982) pigment epithelium ( 418) 2703 599.9 3.9e-171
NP_001316832 (OMIM: 172860,613982) pigment epithel ( 418) 2703 599.9 3.9e-171
NP_001316833 (OMIM: 172860,613982) pigment epithel ( 231) 1509 338.7 8.8e-93
NP_001316834 (OMIM: 172860,613982) pigment epithel ( 231) 1509 338.7 8.8e-93
NP_000925 (OMIM: 262850,613168) alpha-2-antiplasmi ( 491)  607 141.8 3.7e-33
NP_001159392 (OMIM: 262850,613168) alpha-2-antipla ( 491)  607 141.8 3.7e-33
XP_016880254 (OMIM: 262850,613168) PREDICTED: alph ( 495)  607 141.8 3.8e-33
XP_005256758 (OMIM: 262850,613168) PREDICTED: alph ( 507)  607 141.8 3.8e-33
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418)  567 133.0 1.4e-30
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418)  567 133.0 1.4e-30
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418)  567 133.0 1.4e-30
NP_006211 (OMIM: 107410) putative alpha-1-antitryp ( 421)  536 126.2 1.5e-28
NP_001747 (OMIM: 122500,611489) corticosteroid-bin ( 405)  534 125.7   2e-28
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin  ( 423)  527 124.2   6e-28
XP_005267790 (OMIM: 605271) PREDICTED: protein Z-d ( 444)  525 123.8 8.5e-28
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444)  525 123.8 8.5e-28
NP_057270 (OMIM: 605271) protein Z-dependent prote ( 444)  525 123.8 8.5e-28
XP_016876842 (OMIM: 605271) PREDICTED: protein Z-d ( 484)  525 123.8 9.2e-28
NP_000053 (OMIM: 106100,120790,606860) plasma prot ( 500)  522 123.2 1.5e-27
NP_001027466 (OMIM: 106100,120790,606860) plasma p ( 500)  522 123.2 1.5e-27
NP_006206 (OMIM: 147935) kallistatin isoform 2 pre ( 427)  521 122.9 1.5e-27
NP_001275962 (OMIM: 147935) kallistatin isoform 2  ( 427)  521 122.9 1.5e-27
NP_001275961 (OMIM: 147935) kallistatin isoform 1  ( 464)  521 122.9 1.6e-27
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417)  516 121.8 3.2e-27
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417)  516 121.8 3.2e-27
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435)  516 121.8 3.3e-27
NP_000615 (OMIM: 601841) plasma serine protease in ( 406)  500 118.3 3.5e-26
NP_001159393 (OMIM: 262850,613168) alpha-2-antipla ( 427)  500 118.3 3.6e-26
NP_000345 (OMIM: 300932,314200) thyroxine-binding  ( 415)  492 116.6 1.2e-25
NP_001271204 (OMIM: 615677) serpin A9 isoform C [H ( 399)  467 111.1 5.1e-24
NP_001193943 (OMIM: 600943,610504,613848) serpin H ( 418)  448 107.0 9.5e-23
XP_011543629 (OMIM: 600943,610504,613848) PREDICTE ( 418)  448 107.0 9.5e-23
NP_001226 (OMIM: 600943,610504,613848) serpin H1 p ( 418)  448 107.0 9.5e-23
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405)  419 100.6 7.5e-21
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415)  419 100.6 7.6e-21
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416)  418 100.4 8.9e-21
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464)  418 100.4 9.7e-21
XP_006724746 (OMIM: 300932,314200) PREDICTED: thyr ( 425)  415 99.7 1.4e-20
XP_005262237 (OMIM: 300932,314200) PREDICTED: thyr ( 371)  411 98.8 2.3e-20
XP_011535018 (OMIM: 615677) PREDICTED: serpin A9 i ( 337)  403 97.1 7.2e-20
XP_011535019 (OMIM: 615677) PREDICTED: serpin A9 i ( 337)  403 97.1 7.2e-20


>>NP_002606 (OMIM: 172860,613982) pigment epithelium-der  (418 aa)
 initn: 2703 init1: 2703 opt: 2703  Z-score: 3193.4  bits: 599.9 E(85289): 3.9e-171
Smith-Waterman score: 2703; 99.8% identity (99.8% similar) in 418 aa overlap (1-418:1-418)

               10        20        30        40        50        60
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 FGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
       ::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
              310       320       330       340       350       360

              370       380       390       400       410        
pF1KB5 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
              370       380       390       400       410        

>>NP_001316832 (OMIM: 172860,613982) pigment epithelium-  (418 aa)
 initn: 2703 init1: 2703 opt: 2703  Z-score: 3193.4  bits: 599.9 E(85289): 3.9e-171
Smith-Waterman score: 2703; 99.8% identity (99.8% similar) in 418 aa overlap (1-418:1-418)

               10        20        30        40        50        60
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 FGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
       ::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
              310       320       330       340       350       360

              370       380       390       400       410        
pF1KB5 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
              370       380       390       400       410        

>>NP_001316833 (OMIM: 172860,613982) pigment epithelium-  (231 aa)
 initn: 1509 init1: 1509 opt: 1509  Z-score: 1786.7  bits: 338.7 E(85289): 8.8e-93
Smith-Waterman score: 1509; 100.0% identity (100.0% similar) in 231 aa overlap (188-418:1-231)

       160       170       180       190       200       210       
pF1KB5 LEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQW
                                     ::::::::::::::::::::::::::::::
NP_001                               MKGKLARSTKEIPDEISILLLGVAHFKGQW
                                             10        20        30

       220       230       240       250       260       270       
pF1KB5 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
               40        50        60        70        80        90

       280       290       300       310       320       330       
pF1KB5 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
              100       110       120       130       140       150

       340       350       360       370       380       390       
pF1KB5 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
              160       170       180       190       200       210

       400       410        
pF1KB5 LRDTDTGALLFIGKILDPRGP
       :::::::::::::::::::::
NP_001 LRDTDTGALLFIGKILDPRGP
              220       230 

>>NP_001316834 (OMIM: 172860,613982) pigment epithelium-  (231 aa)
 initn: 1509 init1: 1509 opt: 1509  Z-score: 1786.7  bits: 338.7 E(85289): 8.8e-93
Smith-Waterman score: 1509; 100.0% identity (100.0% similar) in 231 aa overlap (188-418:1-231)

       160       170       180       190       200       210       
pF1KB5 LEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQW
                                     ::::::::::::::::::::::::::::::
NP_001                               MKGKLARSTKEIPDEISILLLGVAHFKGQW
                                             10        20        30

       220       230       240       250       260       270       
pF1KB5 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
               40        50        60        70        80        90

       280       290       300       310       320       330       
pF1KB5 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
              100       110       120       130       140       150

       340       350       360       370       380       390       
pF1KB5 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
              160       170       180       190       200       210

       400       410        
pF1KB5 LRDTDTGALLFIGKILDPRGP
       :::::::::::::::::::::
NP_001 LRDTDTGALLFIGKILDPRGP
              220       230 

>>NP_000925 (OMIM: 262850,613168) alpha-2-antiplasmin is  (491 aa)
 initn: 599 init1: 326 opt: 607  Z-score: 716.2  bits: 141.8 E(85289): 3.7e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:31-436)

                                    10        20           30      
pF1KB5                      MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
                                     .:  :  .  :. .::    . :. .: . 
NP_000 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
               10        20        30        40        50        60

              40        50        60        70        80        90 
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
        ::     :  .::  .  ...:: :.  :  ::. . .. :   :..::::::: ::: 
NP_000 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
               70         80        90       100       110         

             100       110       120       130       140       150 
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
       :.:::...: . ....:.    :.: .    ..: . . .:   .. :.:. ..: . ::
NP_000 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
     120       130         140       150         160       170     

             160       170       180       190       200       210 
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
        .:.   :. .:..:  :::. . :: .::.::.   .::. .  . .:..  .:::.. 
NP_000 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
         180       190       200       210       220       230     

             220       230       240       250       260       270 
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
       ::.: : .:::   :. ..:.:::. :: : ::.     ::. :  .   ..:..:. ..
NP_000 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
         240       250       260       270       280       290     

             280       290       300       310       320       330 
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
       ::.. ..: .   :.. .  .:. . .:      . ... :  ::: :... ... .:..
NP_000 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
         300       310       320       330         340       350   

             340       350       360       370       380       390 
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
       . :: ::..::.  :. . . .. :.:.. .: .: :. .. . ..  .....  .. .:
NP_000 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
           360       370       380       390       400        410  

             400       410                                         
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP                                 
       .::.: . .  ::  ::.:.. .:                                    
NP_000 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
            420       430       440       450       460       470  

>>NP_001159392 (OMIM: 262850,613168) alpha-2-antiplasmin  (491 aa)
 initn: 599 init1: 326 opt: 607  Z-score: 716.2  bits: 141.8 E(85289): 3.7e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:31-436)

                                    10        20           30      
pF1KB5                      MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
                                     .:  :  .  :. .::    . :. .: . 
NP_001 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
               10        20        30        40        50        60

              40        50        60        70        80        90 
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
        ::     :  .::  .  ...:: :.  :  ::. . .. :   :..::::::: ::: 
NP_001 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
               70         80        90       100       110         

             100       110       120       130       140       150 
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
       :.:::...: . ....:.    :.: .    ..: . . .:   .. :.:. ..: . ::
NP_001 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
     120       130         140       150         160       170     

             160       170       180       190       200       210 
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
        .:.   :. .:..:  :::. . :: .::.::.   .::. .  . .:..  .:::.. 
NP_001 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
         180       190       200       210       220       230     

             220       230       240       250       260       270 
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
       ::.: : .:::   :. ..:.:::. :: : ::.     ::. :  .   ..:..:. ..
NP_001 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
         240       250       260       270       280       290     

             280       290       300       310       320       330 
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
       ::.. ..: .   :.. .  .:. . .:      . ... :  ::: :... ... .:..
NP_001 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
         300       310       320       330         340       350   

             340       350       360       370       380       390 
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
       . :: ::..::.  :. . . .. :.:.. .: .: :. .. . ..  .....  .. .:
NP_001 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
           360       370       380       390       400        410  

             400       410                                         
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP                                 
       .::.: . .  ::  ::.:.. .:                                    
NP_001 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
            420       430       440       450       460       470  

>>XP_016880254 (OMIM: 262850,613168) PREDICTED: alpha-2-  (495 aa)
 initn: 599 init1: 326 opt: 607  Z-score: 716.2  bits: 141.8 E(85289): 3.8e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:35-440)

                                    10        20           30      
pF1KB5                      MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
                                     .:  :  .  :. .::    . :. .: . 
XP_016 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
           10        20        30        40        50        60    

              40        50        60        70        80        90 
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
        ::     :  .::  .  ...:: :.  :  ::. . .. :   :..::::::: ::: 
XP_016 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
           70        80         90       100       110       120   

             100       110       120       130       140       150 
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
       :.:::...: . ....:.    :.: .    ..: . . .:   .. :.:. ..: . ::
XP_016 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
           130       140         150        160        170         

             160       170       180       190       200       210 
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
        .:.   :. .:..:  :::. . :: .::.::.   .::. .  . .:..  .:::.. 
XP_016 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
     180       190       200       210       220       230         

             220       230       240       250       260       270 
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
       ::.: : .:::   :. ..:.:::. :: : ::.     ::. :  .   ..:..:. ..
XP_016 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
     240       250       260       270       280       290         

             280       290       300       310       320       330 
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
       ::.. ..: .   :.. .  .:. . .:      . ... :  ::: :... ... .:..
XP_016 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
     300       310       320       330       340         350       

             340       350       360       370       380       390 
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
       . :: ::..::.  :. . . .. :.:.. .: .: :. .. . ..  .....  .. .:
XP_016 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
       360       370       380       390       400       410       

             400       410                                         
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP                                 
       .::.: . .  ::  ::.:.. .:                                    
XP_016 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
        420       430       440       450       460       470      

>>XP_005256758 (OMIM: 262850,613168) PREDICTED: alpha-2-  (507 aa)
 initn: 599 init1: 326 opt: 607  Z-score: 716.0  bits: 141.8 E(85289): 3.8e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:47-452)

                                    10        20           30      
pF1KB5                      MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
                                     .:  :  .  :. .::    . :. .: . 
XP_005 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
         20        30        40        50        60        70      

              40        50        60        70        80        90 
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
        ::     :  .::  .  ...:: :.  :  ::. . .. :   :..::::::: ::: 
XP_005 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
         80        90        100       110       120       130     

             100       110       120       130       140       150 
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
       :.:::...: . ....:.    :.: .    ..: . . .:   .. :.:. ..: . ::
XP_005 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
         140       150         160       170         180       190 

             160       170       180       190       200       210 
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
        .:.   :. .:..:  :::. . :: .::.::.   .::. .  . .:..  .:::.. 
XP_005 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
             200       210       220       230       240       250 

             220       230       240       250       260       270 
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
       ::.: : .:::   :. ..:.:::. :: : ::.     ::. :  .   ..:..:. ..
XP_005 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
             260       270       280       290       300       310 

             280       290       300       310       320       330 
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
       ::.. ..: .   :.. .  .:. . .:      . ... :  ::: :... ... .:..
XP_005 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
             320       330       340       350         360         

             340       350       360       370       380       390 
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
       . :: ::..::.  :. . . .. :.:.. .: .: :. .. . ..  .....  .. .:
XP_005 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
     370       380       390       400       410       420         

             400       410                                         
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP                                 
       .::.: . .  ::  ::.:.. .:                                    
XP_005 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
      430       440       450       460       470       480        

>>XP_016876859 (OMIM: 107400,606963,613490) PREDICTED: a  (418 aa)
 initn: 434 init1: 165 opt: 567  Z-score: 670.0  bits: 133.0 E(85289): 1.4e-30
Smith-Waterman score: 567; 28.1% identity (63.1% similar) in 417 aa overlap (13-415:11-415)

               10        20        30         40         50        
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAV
                   ::.   :  :.:  :. . :  ..: .  ...: : :    ::..  .
XP_016   MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNL
                 10        20        30        40            50    

       60        70        80        90       100       110        
pF1KB5 SNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD-
       ..:...:::  . .: .::...::.:.:::.. ::::..  :.. : ..: ..:   :. 
XP_016 AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA
           60        70        80        90       100       110    

        120       130         140       150       160       170    
pF1KB5 -IHGTYKELLDTVTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNP
        ::  ..::: :.. :  : .: ... . . . :.. ..:.  ..: : ..  ... :. 
XP_016 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT
          120       130       140       150       160       170    

           180       190       200       210       220       230   
pF1KB5 RLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYL
       .   ..::..:.   .::..  .::.  .  . :..   :::.:   :. . :  :::..
XP_016 EEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHV
          180       190       200       210       220       230    

           240       250       260            270       280        
pF1KB5 DEERTVRVPMMSDPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTL
       :.  ::.::::.      : :. .   ::     .  .   :. . ::::: .   .:  
XP_016 DQVTTVKVPMMK------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQH
          240             250       260       270       280        

      290       300       310       320       330        340       
pF1KB5 IEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKIT
       .:. :: ..:  . ..    .: : .:::...   .. . : .. . ..: .. :.: .:
XP_016 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT
        290       300       310       320       330       340      

        350       360       370       380       390       400      
pF1KB5 GK-PIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGAL
        . :.::... :.: .  .: :. .. .  :.   ...: . ..:.::.:.. . .: . 
XP_016 EEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSP
        350       360       370       380       390       400      

        410        
pF1KB5 LFIGKILDPRGP
       ::.::...:   
XP_016 LFMGKVVNPTQK
        410        

>>NP_001121177 (OMIM: 107400,606963,613490) alpha-1-anti  (418 aa)
 initn: 434 init1: 165 opt: 567  Z-score: 670.0  bits: 133.0 E(85289): 1.4e-30
Smith-Waterman score: 567; 28.1% identity (63.1% similar) in 417 aa overlap (13-415:11-415)

               10        20        30         40         50        
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAV
                   ::.   :  :.:  :. . :  ..: .  ...: : :    ::..  .
NP_001   MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNL
                 10        20        30        40            50    

       60        70        80        90       100       110        
pF1KB5 SNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD-
       ..:...:::  . .: .::...::.:.:::.. ::::..  :.. : ..: ..:   :. 
NP_001 AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA
           60        70        80        90       100       110    

        120       130         140       150       160       170    
pF1KB5 -IHGTYKELLDTVTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNP
        ::  ..::: :.. :  : .: ... . . . :.. ..:.  ..: : ..  ... :. 
NP_001 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT
          120       130       140       150       160       170    

           180       190       200       210       220       230   
pF1KB5 RLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYL
       .   ..::..:.   .::..  .::.  .  . :..   :::.:   :. . :  :::..
NP_001 EEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHV
          180       190       200       210       220       230    

           240       250       260            270       280        
pF1KB5 DEERTVRVPMMSDPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTL
       :.  ::.::::.      : :. .   ::     .  .   :. . ::::: .   .:  
NP_001 DQVTTVKVPMMK------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQH
          240             250       260       270       280        

      290       300       310       320       330        340       
pF1KB5 IEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKIT
       .:. :: ..:  . ..    .: : .:::...   .. . : .. . ..: .. :.: .:
NP_001 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT
        290       300       310       320       330       340      

        350       360       370       380       390       400      
pF1KB5 GK-PIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGAL
        . :.::... :.: .  .: :. .. .  :.   ...: . ..:.::.:.. . .: . 
NP_001 EEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSP
        350       360       370       380       390       400      

        410        
pF1KB5 LFIGKILDPRGP
       ::.::...:   
NP_001 LFMGKVVNPTQK
        410        




418 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:24:42 2016 done: Sat Nov  5 12:24:43 2016
 Total Scan time:  9.610 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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