Result of FASTA (omim) for pF1KB0413
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0413, 467 aa
  1>>>pF1KB0413 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0852+/-0.000322; mu= 19.7167+/- 0.020
 mean_var=83.9551+/-16.795, 0's: 0 Z-trim(118.1): 62  B-trim: 932 in 1/53
 Lambda= 0.139975
 statistics sampled from 30533 (30630) to 30533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.359), width:  16
 Scan time:  9.660

The best scores are:                                      opt bits E(85289)
NP_071447 (OMIM: 616064) tubulointerstitial nephri ( 467) 3459 708.3 1.1e-203
XP_005271163 (OMIM: 616064) PREDICTED: tubulointer ( 440) 2710 557.0 3.7e-158
XP_005271164 (OMIM: 616064) PREDICTED: tubulointer ( 362) 2638 542.4 7.8e-154
NP_001191344 (OMIM: 616064) tubulointerstitial nep ( 362) 2638 542.4 7.8e-154
XP_011540248 (OMIM: 616064) PREDICTED: tubulointer ( 408) 2474 509.3 7.9e-144
NP_001191343 (OMIM: 616064) tubulointerstitial nep ( 436) 2245 463.1 6.9e-130
XP_006715125 (OMIM: 606749) PREDICTED: tubulointer ( 458) 1525 317.7 4.2e-86
NP_055279 (OMIM: 606749) tubulointerstitial nephri ( 476) 1525 317.7 4.3e-86
XP_016866235 (OMIM: 606749) PREDICTED: tubulointer ( 401) 1345 281.3 3.3e-75
XP_016866234 (OMIM: 606749) PREDICTED: tubulointer ( 438) 1293 270.8 5.2e-72
XP_011512799 (OMIM: 606749) PREDICTED: tubulointer ( 426) 1160 244.0 6.1e-64
XP_016866237 (OMIM: 606749) PREDICTED: tubulointer ( 309) 1157 243.2 7.4e-64
XP_016866236 (OMIM: 606749) PREDICTED: tubulointer ( 351) 1157 243.3 8.2e-64
XP_016868588 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
NP_680091 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  412 92.8 1.5e-18
XP_006716307 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
XP_016868586 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
XP_011542114 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
XP_016868587 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
NP_680092 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  412 92.8 1.5e-18
NP_680093 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  412 92.8 1.5e-18
XP_016868589 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
XP_006716308 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  412 92.8 1.5e-18
NP_001899 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  412 92.8 1.5e-18
NP_680090 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  412 92.8 1.5e-18
XP_016868590 (OMIM: 116810) PREDICTED: cathepsin B ( 245)  336 77.3 5.1e-14
NP_001805 (OMIM: 170650,245000,245010,602365) dipe ( 463)  277 65.7 3.1e-10
NP_001304166 (OMIM: 116810) cathepsin B isoform 2  ( 215)  237 57.3 4.9e-08
NP_001188504 (OMIM: 603308) cathepsin L2 prepropro ( 334)  208 51.6 3.9e-06
NP_001324 (OMIM: 603308) cathepsin L2 preproprotei ( 334)  208 51.6 3.9e-06
NP_000387 (OMIM: 265800,601105) cathepsin K prepro ( 329)  203 50.6 7.7e-06
NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 ( 333)  196 49.2 2.1e-05
NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333)  196 49.2 2.1e-05
XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L ( 333)  196 49.2 2.1e-05
NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333)  196 49.2 2.1e-05
NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 ( 333)  196 49.2 2.1e-05
NP_001244902 (OMIM: 116880) cathepsin L1 isoform 2 ( 151)  190 47.7 2.7e-05
XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L ( 272)  160 41.8  0.0028
XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L ( 272)  160 41.8  0.0028
NP_001326 (OMIM: 602364) cathepsin W preproprotein ( 376)  158 41.6  0.0046
NP_001306066 (OMIM: 116820) pro-cathepsin H isofor ( 201)  151 39.9  0.0078


>>NP_071447 (OMIM: 616064) tubulointerstitial nephritis   (467 aa)
 initn: 3459 init1: 3459 opt: 3459  Z-score: 3777.4  bits: 708.3 E(85289): 1.1e-203
Smith-Waterman score: 3459; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)

               10        20        30        40        50        60
pF1KB0 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
              370       380       390       400       410       420

              430       440       450       460       
pF1KB0 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_071 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
              430       440       450       460       

>>XP_005271163 (OMIM: 616064) PREDICTED: tubulointerstit  (440 aa)
 initn: 2738 init1: 2710 opt: 2710  Z-score: 2960.3  bits: 557.0 E(85289): 3.7e-158
Smith-Waterman score: 2710; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)

               10        20        30        40        50        60
pF1KB0 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
       ::::                                                        
XP_005 GPVQDGERRRCQMEGRSNTGLRPTPGAQPGARGATSASCAASMSATSRASCWASGAAWAW
              370       380       390       400       410       420

>>XP_005271164 (OMIM: 616064) PREDICTED: tubulointerstit  (362 aa)
 initn: 2638 init1: 2638 opt: 2638  Z-score: 2882.8  bits: 542.4 E(85289): 7.8e-154
Smith-Waterman score: 2638; 100.0% identity (100.0% similar) in 362 aa overlap (106-467:1-362)

          80        90       100       110       120       130     
pF1KB0 FCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQC
                                     ::::::::::::::::::::::::::::::
XP_005                               MHGGRIYPVLGTYWDNCNRCTCQENRQWQC
                                             10        20        30

         140       150       160       170       180       190     
pF1KB0 DQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYT
               40        50        60        70        80        90

         200       210       220       230       240       250     
pF1KB0 VLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLS
              100       110       120       130       140       150

         260       270       280       290       300       310     
pF1KB0 PQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRA
              160       170       180       190       200       210

         320       330       340       350       360       370     
pF1KB0 MGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFL
              220       230       240       250       260       270

         380       390       400       410       420       430     
pF1KB0 YKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERG
              280       290       300       310       320       330

         440       450       460       
pF1KB0 HFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       ::::::::::::::::::::::::::::::::
XP_005 HFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
              340       350       360  

>>NP_001191344 (OMIM: 616064) tubulointerstitial nephrit  (362 aa)
 initn: 2638 init1: 2638 opt: 2638  Z-score: 2882.8  bits: 542.4 E(85289): 7.8e-154
Smith-Waterman score: 2638; 100.0% identity (100.0% similar) in 362 aa overlap (106-467:1-362)

          80        90       100       110       120       130     
pF1KB0 FCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQC
                                     ::::::::::::::::::::::::::::::
NP_001                               MHGGRIYPVLGTYWDNCNRCTCQENRQWQC
                                             10        20        30

         140       150       160       170       180       190     
pF1KB0 DQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYT
               40        50        60        70        80        90

         200       210       220       230       240       250     
pF1KB0 VLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLS
              100       110       120       130       140       150

         260       270       280       290       300       310     
pF1KB0 PQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRA
              160       170       180       190       200       210

         320       330       340       350       360       370     
pF1KB0 MGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFL
              220       230       240       250       260       270

         380       390       400       410       420       430     
pF1KB0 YKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERG
              280       290       300       310       320       330

         440       450       460       
pF1KB0 HFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       ::::::::::::::::::::::::::::::::
NP_001 HFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
              340       350       360  

>>XP_011540248 (OMIM: 616064) PREDICTED: tubulointerstit  (408 aa)
 initn: 2474 init1: 2474 opt: 2474  Z-score: 2703.2  bits: 509.3 E(85289): 7.9e-144
Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 342 aa overlap (126-467:67-408)

         100       110       120       130       140       150     
pF1KB0 PPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNY
                                     ::::::::::::::::::::::::::::::
XP_011 PLLTLSVRRSQSQEAEARGPAWAPAHTFTSTCQENRQWQCDQEPCLVDPDMIKAINQGNY
         40        50        60        70        80        90      

         160       170       180       190       200       210     
pF1KB0 GWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPN
        100       110       120       130       140       150      

         220       230       240       250       260       270     
pF1KB0 LIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRL
        160       170       180       190       200       210      

         280       290       300       310       320       330     
pF1KB0 DGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNN
        220       230       240       250       260       270      

         340       350       360       370       380       390     
pF1KB0 DIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYR
        280       290       300       310       320       330      

         400       410       420       430       440       450     
pF1KB0 RHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGV
        340       350       360       370       380       390      

         460       
pF1KB0 WGRVGMEDMGHH
       ::::::::::::
XP_011 WGRVGMEDMGHH
        400        

>>NP_001191343 (OMIM: 616064) tubulointerstitial nephrit  (436 aa)
 initn: 2237 init1: 2237 opt: 2245  Z-score: 2452.9  bits: 463.1 E(85289): 6.9e-130
Smith-Waterman score: 3147; 93.4% identity (93.4% similar) in 467 aa overlap (1-467:1-436)

               10        20        30        40        50        60
pF1KB0 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
       :::::                               ::::::::::::::::::::::::
NP_001 NCNRC-------------------------------WQAGNHSAFWGMTLDEGIRYRLGT
                                             130       140         

              190       200       210       220       230       240
pF1KB0 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
     150       160       170       180       190       200         

              250       260       270       280       290       300
pF1KB0 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
     210       220       230       240       250       260         

              310       320       330       340       350       360
pF1KB0 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
     270       280       290       300       310       320         

              370       380       390       400       410       420
pF1KB0 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
     330       340       350       360       370       380         

              430       440       450       460       
pF1KB0 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
     390       400       410       420       430      

>>XP_006715125 (OMIM: 606749) PREDICTED: tubulointerstit  (458 aa)
 initn: 1451 init1: 664 opt: 1525  Z-score: 1666.8  bits: 317.7 E(85289): 4.2e-86
Smith-Waterman score: 1525; 49.4% identity (73.5% similar) in 427 aa overlap (45-463:36-456)

           20        30        40        50        60          70  
pF1KB0 AGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGA--ICY
                                     :.::..   ::. : : :.  . .:  .::
XP_006 LSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNFG-CCEDRDDGCVTEFYAANALCY
          10        20        30        40         50        60    

             80        90             100       110       120      
pF1KB0 CDLFCNRTVSDCCPDFWDFCLGV---PP---PFPPIQGCMHGGRIYPVLGTYWDNCNRCT
       :: ::.:  ::::::. .::      ::   :. : .::.. :. :   ..  .::: ::
XP_006 CDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYP-EGCFKDGQHYEEGSVIKENCNSCT
           70        80        90        100       110       120   

        130       140       150       160       170       180      
pF1KB0 CQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSS
       :. ..::.:.:. :::  ..:. .:.:.::: : :.: ::::::..:...::::. ::  
XP_006 CS-GQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPM
            130       140       150       160       170       180  

        190       200       210       220       230       240      
pF1KB0 VMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHS
       ...:.:. . :     ::  : :: :::.  : :::: :::.:::::::.::.::..:.:
XP_006 LLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQS
            190       200       210       220       230       240  

        250       260       270       280       290       300      
pF1KB0 LGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPA
        :..:  ::::::.:: .....:: .: .: :::.::.::.::  :::.    .:. .  
XP_006 KGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPL---FKDQNATN
            250       260       270       280       290            

        310       320       330       340       350       360      
pF1KB0 PPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQAL
         : : ::. :::::.::  :::.  ..: ::: .: ::..::. :::::.:.::::::.
XP_006 NGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAI
     300       310       320       330       340       350         

        370       380       390       400       410       420      
pF1KB0 MEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANS
       :.:.:::: :: ::: :.  .  . :.::.  ::.::.::::     .:.  :.: ::::
XP_006 MQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANS
     360       370       380       390       400       410         

        430       440       450       460       
pF1KB0 WGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       :: .::: :.:::.::::: :::......::..   :    
XP_006 WGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP  
     420       430       440       450          

>>NP_055279 (OMIM: 606749) tubulointerstitial nephritis   (476 aa)
 initn: 1451 init1: 664 opt: 1525  Z-score: 1666.6  bits: 317.7 E(85289): 4.3e-86
Smith-Waterman score: 1525; 49.4% identity (73.5% similar) in 427 aa overlap (45-463:54-474)

           20        30        40        50        60          70  
pF1KB0 AGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGA--ICY
                                     :.::..   ::. : : :.  . .:  .::
NP_055 LSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNFG-CCEDRDDGCVTEFYAANALCY
            30        40        50        60         70        80  

             80        90             100       110       120      
pF1KB0 CDLFCNRTVSDCCPDFWDFCLGV---PP---PFPPIQGCMHGGRIYPVLGTYWDNCNRCT
       :: ::.:  ::::::. .::      ::   :. : .::.. :. :   ..  .::: ::
NP_055 CDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYP-EGCFKDGQHYEEGSVIKENCNSCT
             90       100       110        120       130       140 

        130       140       150       160       170       180      
pF1KB0 CQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSS
       :. ..::.:.:. :::  ..:. .:.:.::: : :.: ::::::..:...::::. ::  
NP_055 CS-GQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPM
              150       160       170       180       190       200

        190       200       210       220       230       240      
pF1KB0 VMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHS
       ...:.:. . :     ::  : :: :::.  : :::: :::.:::::::.::.::..:.:
NP_055 LLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQS
              210       220       230       240       250       260

        250       260       270       280       290       300      
pF1KB0 LGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPA
        :..:  ::::::.:: .....:: .: .: :::.::.::.::  :::.    .:. .  
NP_055 KGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPL---FKDQNATN
              270       280       290       300          310       

        310       320       330       340       350       360      
pF1KB0 PPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQAL
         : : ::. :::::.::  :::.  ..: ::: .: ::..::. :::::.:.::::::.
NP_055 NGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAI
       320       330       340       350       360       370       

        370       380       390       400       410       420      
pF1KB0 MEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANS
       :.:.:::: :: ::: :.  .  . :.::.  ::.::.::::     .:.  :.: ::::
NP_055 MQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANS
       380       390       400       410       420       430       

        430       440       450       460       
pF1KB0 WGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       :: .::: :.:::.::::: :::......::..   :    
NP_055 WGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP  
       440       450       460       470        

>>XP_016866235 (OMIM: 606749) PREDICTED: tubulointerstit  (401 aa)
 initn: 1321 init1: 664 opt: 1345  Z-score: 1471.1  bits: 281.3 E(85289): 3.3e-75
Smith-Waterman score: 1345; 50.8% identity (76.0% similar) in 362 aa overlap (102-463:42-399)

              80        90       100       110       120       130 
pF1KB0 YCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENR
                                     .:::.. :. :   ..  .::: :::. ..
XP_016 YLTTEIWMEKQYLSQREVDLEAYFTRNHTVLQGCFKDGQHYEEGSVIKENCNSCTCS-GQ
              20        30        40        50        60         70

             140       150       160       170       180       190 
pF1KB0 QWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMH
       ::.:.:. :::  ..:. .:.:.::: : :.: ::::::..:...::::. ::  ...:.
XP_016 QWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMN
               80        90       100       110       120       130

             200       210       220       230       240       250 
pF1KB0 EIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMT
       :. . :     ::  : :: :::.  : :::: :::.:::::::.::.::..:.: :..:
XP_016 EMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYT
              140       150       160       170       180       190

             260       270       280       290       300       310 
pF1KB0 PVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMM
         ::::::.:: .....:: .: .: :::.::.::.::  :::.    .:. .    : :
XP_016 ANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPL---FKDQNATNNGCAM
              200       210       220       230          240       

             320       330       340       350       360       370 
pF1KB0 HSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHE
        ::. :::::.::  :::.  ..: ::: .: ::..::. :::::.:.::::::.:.:.:
XP_016 ASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVRE
       250       260       270       280       290       300       

             380       390       400       410       420       430 
pF1KB0 DFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAW
       ::: :: ::: :.  .  . :.::.  ::.::.::::     .:.  :.: :::::: .:
XP_016 DFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSW
       310       320       330       340       350       360       

             440       450       460       
pF1KB0 GERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
       :: :.:::.::::: :::......::..   :    
XP_016 GENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP  
       370       380       390       400   

>>XP_016866234 (OMIM: 606749) PREDICTED: tubulointerstit  (438 aa)
 initn: 1239 init1: 664 opt: 1293  Z-score: 1413.9  bits: 270.8 E(85289): 5.2e-72
Smith-Waterman score: 1293; 49.2% identity (73.2% similar) in 370 aa overlap (45-406:54-417)

           20        30        40        50        60          70  
pF1KB0 AGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGA--ICY
                                     :.::..   ::. : : :.  . .:  .::
XP_016 LSQREVDLEAYFTRNHTVLQGTRFKRAIFQGQYCRNFG-CCEDRDDGCVTEFYAANALCY
            30        40        50        60         70        80  

             80        90             100       110       120      
pF1KB0 CDLFCNRTVSDCCPDFWDFCLGV---PP---PFPPIQGCMHGGRIYPVLGTYWDNCNRCT
       :: ::.:  ::::::. .::      ::   :. : .::.. :. :   ..  .::: ::
XP_016 CDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYP-EGCFKDGQHYEEGSVIKENCNSCT
             90       100       110        120       130       140 

        130       140       150       160       170       180      
pF1KB0 CQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSS
       :. ..::.:.:. :::  ..:. .:.:.::: : :.: ::::::..:...::::. ::  
XP_016 CS-GQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLEDGFKFRLGTLPPSPM
              150       160       170       180       190       200

        190       200       210       220       230       240      
pF1KB0 VMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHS
       ...:.:. . :     ::  : :: :::.  : :::: :::.:::::::.::.::..:.:
XP_016 LLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQS
              210       220       230       240       250       260

        250       260       270       280       290       300      
pF1KB0 LGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPA
        :..:  ::::::.:: .....:: .: .: :::.::.::.::  :::.    .:. .  
XP_016 KGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPLF---KDQNATN
              270       280       290       300       310          

        310       320       330       340       350       360      
pF1KB0 PPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQAL
         : : ::. :::::.::  :::.  ..: ::: .: ::..::. :::::.:.::::::.
XP_016 NGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAI
       320       330       340       350       360       370       

        370       380       390       400       410       420      
pF1KB0 MEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANS
       :.:.:::: :: ::: :.  .  . :.::.  ::.::.::                    
XP_016 MQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGLLPIPGESHGERMAISGFFE
       380       390       400       410       420       430       

        430       440       450       460       
pF1KB0 WGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
                                                
XP_016 E                                        
                                                




467 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:52:02 2016 done: Sat Nov  5 11:52:03 2016
 Total Scan time:  9.660 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com