Result of FASTA (omim) for pF1KB8561
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8561, 967 aa
  1>>>pF1KB8561 967 - 967 aa - 967 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.0877+/-0.000575; mu= 1.4634+/- 0.035
 mean_var=681.6520+/-155.534, 0's: 0 Z-trim(117.7): 1160  B-trim: 33 in 1/59
 Lambda= 0.049124
 statistics sampled from 28395 (29909) to 28395 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.351), width:  16
 Scan time: 14.720

The best scores are:                                      opt bits E(85289)
NP_775267 (OMIM: 601212) protein-tyrosine kinase 2 ( 967) 6482 476.5 2.8e-133
XP_005273505 (OMIM: 601212) PREDICTED: protein-tyr ( 997) 5012 372.4 6.5e-102
XP_016868703 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
XP_011542743 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
NP_004094 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
NP_775266 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
XP_005273504 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
NP_775268 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
XP_016868705 (OMIM: 601212) PREDICTED: protein-tyr ( 984) 2546 197.6 2.6e-49
XP_016868704 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 2546 197.6 2.7e-49
XP_011542744 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 2546 197.6 2.7e-49
XP_016869148 (OMIM: 600758) PREDICTED: focal adhes (1031) 2266 177.8 2.5e-43
XP_016869165 (OMIM: 600758) PREDICTED: focal adhes (1034) 2266 177.8 2.6e-43
NP_722560 (OMIM: 600758) focal adhesion kinase 1 i (1052) 2266 177.8 2.6e-43
XP_016869162 (OMIM: 600758) PREDICTED: focal adhes (1052) 2266 177.8 2.6e-43
XP_016869160 (OMIM: 600758) PREDICTED: focal adhes (1055) 2266 177.8 2.6e-43
XP_016869161 (OMIM: 600758) PREDICTED: focal adhes (1055) 2266 177.8 2.6e-43
NP_001186578 (OMIM: 600758) focal adhesion kinase  (1065) 2266 177.8 2.6e-43
NP_005598 (OMIM: 600758) focal adhesion kinase 1 i (1074) 2266 177.8 2.6e-43
XP_016869146 (OMIM: 600758) PREDICTED: focal adhes (1099) 2266 177.8 2.6e-43
XP_016869175 (OMIM: 600758) PREDICTED: focal adhes ( 942) 2053 162.6 8.5e-39
XP_016869174 (OMIM: 600758) PREDICTED: focal adhes ( 948) 1438 119.1 1.1e-25
XP_016869159 (OMIM: 600758) PREDICTED: focal adhes (1058) 1438 119.1 1.2e-25
XP_016869154 (OMIM: 600758) PREDICTED: focal adhes (1061) 1438 119.1 1.2e-25
XP_016869153 (OMIM: 600758) PREDICTED: focal adhes (1061) 1438 119.1 1.2e-25
XP_016869167 (OMIM: 600758) PREDICTED: focal adhes (1016) 1409 117.1 4.9e-25
XP_016869155 (OMIM: 600758) PREDICTED: focal adhes (1060) 1409 117.1   5e-25
XP_016869173 (OMIM: 600758) PREDICTED: focal adhes ( 949) 1400 116.4 7.3e-25
XP_016869158 (OMIM: 600758) PREDICTED: focal adhes (1059) 1400 116.4 7.7e-25
XP_016869151 (OMIM: 600758) PREDICTED: focal adhes (1062) 1400 116.4 7.7e-25
XP_016869152 (OMIM: 600758) PREDICTED: focal adhes (1062) 1400 116.4 7.7e-25
XP_016869145 (OMIM: 600758) PREDICTED: focal adhes (1103) 1400 116.5 7.9e-25
XP_016869143 (OMIM: 600758) PREDICTED: focal adhes (1106) 1400 116.5 7.9e-25
XP_016869179 (OMIM: 600758) PREDICTED: focal adhes ( 913) 1354 113.1 6.9e-24
XP_016869171 (OMIM: 600758) PREDICTED: focal adhes ( 976) 1243 105.3 1.7e-21
XP_016869147 (OMIM: 600758) PREDICTED: focal adhes (1089) 1243 105.3 1.7e-21
XP_016869178 (OMIM: 600758) PREDICTED: focal adhes ( 919) 1212 103.0 7.4e-21
XP_016869177 (OMIM: 600758) PREDICTED: focal adhes ( 919) 1212 103.0 7.4e-21
XP_016869176 (OMIM: 600758) PREDICTED: focal adhes ( 934) 1212 103.0 7.4e-21
XP_016869172 (OMIM: 600758) PREDICTED: focal adhes ( 955) 1212 103.0 7.5e-21
NP_001303271 (OMIM: 600758) focal adhesion kinase  ( 955) 1212 103.0 7.5e-21
XP_016869170 (OMIM: 600758) PREDICTED: focal adhes ( 980) 1212 103.1 7.6e-21
XP_006716672 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_006716673 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_005251070 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_016869169 (OMIM: 600758) PREDICTED: focal adhes ( 995) 1212 103.1 7.7e-21
XP_016869168 (OMIM: 600758) PREDICTED: focal adhes (1011) 1212 103.1 7.7e-21
XP_016869166 (OMIM: 600758) PREDICTED: focal adhes (1032) 1212 103.1 7.8e-21
XP_016869164 (OMIM: 600758) PREDICTED: focal adhes (1047) 1212 103.1 7.9e-21
XP_016869163 (OMIM: 600758) PREDICTED: focal adhes (1047) 1212 103.1 7.9e-21


>>NP_775267 (OMIM: 601212) protein-tyrosine kinase 2-bet  (967 aa)
 initn: 6482 init1: 6482 opt: 6482  Z-score: 2513.8  bits: 476.5 E(85289): 2.8e-133
Smith-Waterman score: 6482; 99.9% identity (99.9% similar) in 967 aa overlap (1-967:1-967)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 KYRPPPQTNLLAPKLQFQEEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KYRPPPQTNLLAPKLQFQEEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB8 RQEEKSLDPMVYMNDTSPLTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYL
       ::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_775 RQEEKSLDPMVYMNDKSPLTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB8 NVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB8 QKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 QKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLAN
              910       920       930       940       950       960

              
pF1KB8 LAHPPAE
       :::::::
NP_775 LAHPPAE
              

>>XP_005273505 (OMIM: 601212) PREDICTED: protein-tyrosin  (997 aa)
 initn: 6069 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.5e-102
Smith-Waterman score: 6275; 94.6% identity (94.6% similar) in 1009 aa overlap (1-967:1-997)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_005 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_005 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSL-----------
              790       800       810       820                    

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -TPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
      830       840       850       860       870       880        

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
      890       900       910       920       930       940        

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
      950       960       970       980       990       

>>XP_016868703 (OMIM: 601212) PREDICTED: protein-tyrosin  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>XP_011542743 (OMIM: 601212) PREDICTED: protein-tyrosin  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_011 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
XP_011 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>NP_004094 (OMIM: 601212) protein-tyrosine kinase 2-bet  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
NP_004 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_004 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
NP_004 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>NP_775266 (OMIM: 601212) protein-tyrosine kinase 2-bet  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
NP_775 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_775 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
NP_775 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>XP_005273504 (OMIM: 601212) PREDICTED: protein-tyrosin  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_005 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
XP_005 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>NP_775268 (OMIM: 601212) protein-tyrosine kinase 2-bet  (1009 aa)
 initn: 5012 init1: 5012 opt: 5012  Z-score: 1950.6  bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
              670       680       690       700       710       720

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
NP_775 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
              730       740       750       760       770       780

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_775 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
              790       800       810       820       830       840

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
              850       860       870       880       890       900

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
              910       920       930       940       950       960

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
NP_775 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
              970       980       990      1000         

>>XP_016868705 (OMIM: 601212) PREDICTED: protein-tyrosin  (984 aa)
 initn: 3603 init1: 2546 opt: 2546  Z-score: 1006.1  bits: 197.6 E(85289): 2.6e-49
Smith-Waterman score: 6147; 93.4% identity (93.4% similar) in 1009 aa overlap (1-967:1-984)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQ-----
              310       320       330       340       350          

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------DGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
                 360       370       380       390       400       

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       410       420       430       440       450       460       

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       470       480       490       500       510       520       

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       530       540       550       560       570       580       

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       590       600       610       620       630       640       

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       650       660       670       680       690       700       

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
       710       720       730       740       750       760       

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSL-----------
       770       780       790       800       810                 

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -TPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
         820       830       840       850       860       870     

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
         880       890       900       910       920       930     

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
         940       950       960       970       980    

>>XP_016868704 (OMIM: 601212) PREDICTED: protein-tyrosin  (996 aa)
 initn: 3846 init1: 2546 opt: 2546  Z-score: 1006.1  bits: 197.6 E(85289): 2.7e-49
Smith-Waterman score: 6192; 94.4% identity (94.4% similar) in 999 aa overlap (1-957:1-986)

               10        20        30        40        50        60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQ-----
              310       320       330       340       350          

              370       380       390       400       410       420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------DGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
                 360       370       380       390       400       

              430       440       450       460       470       480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
       410       420       430       440       450       460       

              490       500       510       520       530       540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
       470       480       490       500       510       520       

              550       560       570       580       590       600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
       530       540       550       560       570       580       

              610       620       630       640       650       660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
       590       600       610       620       630       640       

              670       680       690       700       710       720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
       650       660       670       680       690       700       

              730                                                  
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
       ::::::::::::::::::                                          
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
       710       720       730       740       750       760       

      740       750       760       770       780       790        
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
       770       780       790       800       810       820       

      800       810       820       830       840       850        
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
       830       840       850       860       870       880       

      860       870       880       890       900       910        
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
       890       900       910       920       930       940       

      920       930       940       950       960       
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       :::::::::::::::::::::::::::::::::::::::          
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
       950       960       970       980       990      




967 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:49:02 2016 done: Sat Nov  5 11:49:04 2016
 Total Scan time: 14.720 Total Display time:  0.410

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com