Result of FASTA (omim) for pF1KB6605
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6605, 393 aa
  1>>>pF1KB6605 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6335+/-0.000322; mu= 14.2781+/- 0.020
 mean_var=174.1313+/-35.354, 0's: 0 Z-trim(121.1): 22  B-trim: 150 in 1/52
 Lambda= 0.097193
 statistics sampled from 37307 (37332) to 37307 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.438), width:  16
 Scan time:  7.010

The best scores are:                                      opt bits E(85289)
NP_001018079 (OMIM: 607378) plasminogen activator  ( 393) 2706 391.1 2.4e-108
NP_056455 (OMIM: 607378) plasminogen activator inh ( 387) 2643 382.3 1.1e-105
NP_001018077 (OMIM: 607378) plasminogen activator  ( 408) 1636 241.1 3.6e-63
NP_001018078 (OMIM: 607378) plasminogen activator  ( 402) 1616 238.3 2.5e-62


>>NP_001018079 (OMIM: 607378) plasminogen activator inhi  (393 aa)
 initn: 2706 init1: 2706 opt: 2706  Z-score: 2066.2  bits: 391.1 E(85289): 2.4e-108
Smith-Waterman score: 2706; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)

               10        20        30        40        50        60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
              310       320       330       340       350       360

              370       380       390   
pF1KB6 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
       :::::::::::::::::::::::::::::::::
NP_001 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
              370       380       390   

>>NP_056455 (OMIM: 607378) plasminogen activator inhibit  (387 aa)
 initn: 1678 init1: 1402 opt: 2643  Z-score: 2018.6  bits: 382.3 E(85289): 1.1e-105
Smith-Waterman score: 2643; 98.5% identity (98.5% similar) in 393 aa overlap (1-393:1-387)

               10        20        30        40        50        60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
       ::::::::::::::::::::::      ::::::::::::::::::::::::::::::::
NP_056 RGDGFDSRGKREFDRHSGSDRS------GLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
              190       200             210       220       230    

              250       260       270       280       290       300
pF1KB6 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KB6 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
          300       310       320       330       340       350    

              370       380       390   
pF1KB6 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
       :::::::::::::::::::::::::::::::::
NP_056 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
          360       370       380       

>>NP_001018077 (OMIM: 607378) plasminogen activator inhi  (408 aa)
 initn: 1952 init1: 1604 opt: 1636  Z-score: 1255.2  bits: 241.1 E(85289): 3.6e-63
Smith-Waterman score: 2666; 96.3% identity (96.3% similar) in 408 aa overlap (1-393:1-408)

               10        20        30        40        50        60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELT--------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
NP_001 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
              190       200       210       220       230       240

                   240       250       260       270       280     
pF1KB6 -------DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KB6 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
              310       320       330       340       350       360

         350       360       370       380       390   
pF1KB6 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
              370       380       390       400        

>>NP_001018078 (OMIM: 607378) plasminogen activator inhi  (402 aa)
 initn: 1750 init1: 1402 opt: 1616  Z-score: 1240.1  bits: 238.3 E(85289): 2.5e-62
Smith-Waterman score: 2603; 94.9% identity (94.9% similar) in 408 aa overlap (1-393:1-402)

               10        20        30        40        50        60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELT--------
       ::::::::::::::::::::::      ::::::::::::::::::::::::        
NP_001 RGDGFDSRGKREFDRHSGSDRS------GLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
              190       200             210       220       230    

                   240       250       260       270       280     
pF1KB6 -------DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
          240       250       260       270       280       290    

         290       300       310       320       330       340     
pF1KB6 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
          300       310       320       330       340       350    

         350       360       370       380       390   
pF1KB6 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
          360       370       380       390       400  




393 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:32:29 2016 done: Sat Nov  5 11:32:30 2016
 Total Scan time:  7.010 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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