Result of FASTA (omim) for pF1KB6570
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6570, 400 aa
  1>>>pF1KB6570 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6331+/-0.000362; mu= 15.5849+/- 0.023
 mean_var=77.2689+/-15.544, 0's: 0 Z-trim(113.9): 9  B-trim: 0 in 0/55
 Lambda= 0.145906
 statistics sampled from 23512 (23519) to 23512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.276), width:  16
 Scan time:  8.900

The best scores are:                                      opt bits E(85289)
NP_002452 (OMIM: 603236,614714) diphosphomevalonat ( 400) 2677 573.1 4.1e-163
XP_011521390 (OMIM: 603236,614714) PREDICTED: diph ( 379) 2519 539.8 4.1e-153
XP_011521391 (OMIM: 603236,614714) PREDICTED: diph ( 283) 1790 386.3  5e-107
XP_011521389 (OMIM: 603236,614714) PREDICTED: diph ( 413) 1790 386.4 6.8e-107
XP_011521388 (OMIM: 603236,614714) PREDICTED: diph ( 434) 1790 386.4 7.1e-107


>>NP_002452 (OMIM: 603236,614714) diphosphomevalonate de  (400 aa)
 initn: 2677 init1: 2677 opt: 2677  Z-score: 3049.3  bits: 573.1 E(85289): 4.1e-163
Smith-Waterman score: 2677; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
       ::::::::::::::::::::::::::::::::::::::::
NP_002 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
              370       380       390       400

>>XP_011521390 (OMIM: 603236,614714) PREDICTED: diphosph  (379 aa)
 initn: 2519 init1: 2519 opt: 2519  Z-score: 2869.9  bits: 539.8 E(85289): 4.1e-153
Smith-Waterman score: 2519; 100.0% identity (100.0% similar) in 376 aa overlap (25-400:4-379)

               10        20        30        40        50        60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
                               ::::::::::::::::::::::::::::::::::::
XP_011                      MNRGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
                                    10        20        30         

               70        80        90       100       110       120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KB6 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KB6 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KB6 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KB6 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
     280       290       300       310       320       330         

              370       380       390       400
pF1KB6 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
       ::::::::::::::::::::::::::::::::::::::::
XP_011 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
     340       350       360       370         

>>XP_011521391 (OMIM: 603236,614714) PREDICTED: diphosph  (283 aa)
 initn: 1790 init1: 1790 opt: 1790  Z-score: 2042.5  bits: 386.3 E(85289): 5e-107
Smith-Waterman score: 1790; 100.0% identity (100.0% similar) in 265 aa overlap (136-400:19-283)

         110       120       130       140       150       160     
pF1KB6 LSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYG
                                     ::::::::::::::::::::::::::::::
XP_011             MGEKHCRPGVQDQPGQHTYTLARVYGVESDLSEVARRGSGSACRSLYG
                           10        20        30        40        

         170       180       190       200       210       220     
pF1KB6 GFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLL
       50        60        70        80        90       100        

         230       240       250       260       270       280     
pF1KB6 RFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRII
      110       120       130       140       150       160        

         290       300       310       320       330       340     
pF1KB6 HLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQV
      170       180       190       200       210       220        

         350       360       370       380       390       400
pF1KB6 RPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
      230       240       250       260       270       280   

>>XP_011521389 (OMIM: 603236,614714) PREDICTED: diphosph  (413 aa)
 initn: 2500 init1: 1790 opt: 1790  Z-score: 2040.1  bits: 386.4 E(85289): 6.8e-107
Smith-Waterman score: 2436; 91.5% identity (91.7% similar) in 410 aa overlap (25-400:4-413)

               10        20        30        40        50        60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
                               ::::::::::::::::::::::::::::::::::::
XP_011                      MNRGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
                                    10        20        30         

               70        80        90       100       110       120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
      40        50        60        70        80        90         

              130                                         140      
pF1KB6 AAGLASSAAGYACLA----------------------------------YTLARVYGVES
       ::::::::::::::.                                  :::::::::::
XP_011 AAGLASSAAGYACLVAAGVGLSPVIPVLKRLMGEKHCRPGVQDQPGQHTYTLARVYGVES
     100       110       120       130       140       150         

        150       160       170       180       190       200      
pF1KB6 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
     160       170       180       190       200       210         

        210       220       230       240       250       260      
pF1KB6 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
     220       230       240       250       260       270         

        270       280       290       300       310       320      
pF1KB6 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
     280       290       300       310       320       330         

        330       340       350       360       370       380      
pF1KB6 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
     340       350       360       370       380       390         

        390       400
pF1KB6 AHLLGPDGLPKPAA
       ::::::::::::::
XP_011 AHLLGPDGLPKPAA
     400       410   

>>XP_011521388 (OMIM: 603236,614714) PREDICTED: diphosph  (434 aa)
 initn: 2658 init1: 1790 opt: 1790  Z-score: 2039.7  bits: 386.4 E(85289): 7.1e-107
Smith-Waterman score: 2582; 91.9% identity (92.1% similar) in 432 aa overlap (3-400:3-434)

               10        20        30        40        50        60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
               70        80        90       100       110       120

              130                                         140      
pF1KB6 AAGLASSAAGYACLA----------------------------------YTLARVYGVES
       ::::::::::::::.                                  :::::::::::
XP_011 AAGLASSAAGYACLVAAGVGLSPVIPVLKRLMGEKHCRPGVQDQPGQHTYTLARVYGVES
              130       140       150       160       170       180

        150       160       170       180       190       200      
pF1KB6 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
              190       200       210       220       230       240

        210       220       230       240       250       260      
pF1KB6 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
              250       260       270       280       290       300

        270       280       290       300       310       320      
pF1KB6 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
              310       320       330       340       350       360

        330       340       350       360       370       380      
pF1KB6 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
              370       380       390       400       410       420

        390       400
pF1KB6 AHLLGPDGLPKPAA
       ::::::::::::::
XP_011 AHLLGPDGLPKPAA
              430    




400 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:29:20 2016 done: Sat Nov  5 11:29:22 2016
 Total Scan time:  8.900 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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