Result of FASTA (ccds) for pF1KB9824
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9824, 315 aa
  1>>>pF1KB9824 315 - 315 aa - 315 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9752+/-0.000781; mu= 5.5556+/- 0.048
 mean_var=175.3239+/-33.809, 0's: 0 Z-trim(115.7): 20  B-trim: 48 in 1/50
 Lambda= 0.096862
 statistics sampled from 16202 (16219) to 16202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.498), width:  16
 Scan time:  3.020

The best scores are:                                      opt bits E(32554)
CCDS9463.1 SPRY2 gene_id:10253|Hs108|chr13         ( 315) 2291 331.4 5.6e-91
CCDS3731.1 SPRY1 gene_id:10252|Hs108|chr4          ( 319) 1131 169.3 3.5e-42
CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrY         ( 288)  885 134.9 7.3e-32
CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrX         ( 288)  885 134.9 7.3e-32
CCDS47296.1 SPRY4 gene_id:81848|Hs108|chr5         ( 299)  830 127.2 1.5e-29
CCDS4274.1 SPRY4 gene_id:81848|Hs108|chr5          ( 322)  830 127.2 1.6e-29


>>CCDS9463.1 SPRY2 gene_id:10253|Hs108|chr13              (315 aa)
 initn: 2291 init1: 2291 opt: 2291  Z-score: 1746.8  bits: 331.4 E(32554): 5.6e-91
Smith-Waterman score: 2291; 100.0% identity (100.0% similar) in 315 aa overlap (1-315:1-315)

               10        20        30        40        50        60
pF1KB9 MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 VVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 VVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 STRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 STRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 CGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 CGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 PCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 PCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVC
              250       260       270       280       290       300

              310     
pF1KB9 CKVPTVPPRNFEKPT
       :::::::::::::::
CCDS94 CKVPTVPPRNFEKPT
              310     

>>CCDS3731.1 SPRY1 gene_id:10252|Hs108|chr4               (319 aa)
 initn: 1013 init1: 461 opt: 1131  Z-score: 870.7  bits: 169.3 E(32554): 3.5e-42
Smith-Waterman score: 1152; 55.2% identity (73.0% similar) in 330 aa overlap (1-315:1-319)

               10         20        30        40        50         
pF1KB9 MEARAQSGNGSQ-PLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGP
       :. . : :.::.  ..: :   .::: . . :.   : . .::::::.:::..:::::::
CCDS37 MDPQNQHGSGSSLVVIQQPSLDSRQRLDYE-RE--IQPTAILSLDQIKAIRGSNEYTEGP
               10        20        30           40        50       

      60        70        80                90       100        110
pF1KB9 TVVPRPGLKPAPRPSTQHKHERLHGL-P-------EHRQPPRLQHSQVHSSARAP-LSRS
       .:: ::. . :::   :.:::: : . :       :::.  .: :. . :.::.: ::::
CCDS37 SVVKRPAPRTAPR---QEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRS
        60        70           80        90       100       110    

              120       130       140           150       160      
pF1KB9 ISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPV----ADGIIRVQPKSELKPGELKPL
        ::   :: .:.  :.::.:::: ::: :  . ::    ..  ::.::: .:   .::  
CCDS37 TST---GSAASS-GSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPK-QLIVDDLKGS
             120        130       140       150        160         

        170       180       190       200       210       220      
pF1KB9 SKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLF
        ::::  : . ::.:::::: ::: :: :::   :..::::::.....::::.: :::.:
CCDS37 LKEDLTQHKFICEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIF
     170       180       190       200       210       220         

        230        240       250       260       270       280     
pF1KB9 YHCSNDDE-DNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDR
       :::::::: :. .::::::::::::.:.  ::.:::::::: :: :::::::::. ::: 
CCDS37 YHCSNDDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDW
     230       240       250       260       270       280         

         290       300       310     
pF1KB9 VNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
       ..:::::::::::: ::. . : :.  ::.
CCDS37 IHRPGCRCKNSNTVYCKLESCPSRGQGKPS
     290       300       310         

>>CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrY              (288 aa)
 initn: 851 init1: 727 opt: 885  Z-score: 685.5  bits: 134.9 E(32554): 7.3e-32
Smith-Waterman score: 885; 46.4% identity (69.9% similar) in 289 aa overlap (39-313:11-286)

       10        20        30        40        50        60        
pF1KB9 NGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLK
                                     ..: ..:.:. . .:.:.: :   : :  .
CCDS14                     MDAAVTDDFQQILPIEQLRSTHASNDYVERP---PAPCKQ
                                   10        20        30          

       70           80         90       100       110       120    
pF1KB9 PAPRPST---QHKHE-RLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRT
           ::     :: .  :  .:     :: . :: :.    :   : :...:.       
CCDS14 ALSSPSLIVQTHKSDWSLATMPTSL--PR-SLSQCHQLQPLPQHLSQSSIASS------M
        40        50        60           70        80              

          130       140       150       160          170           
pF1KB9 STSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKP---GELKPLSKEDLGL---HAYRC
       : :...:.:::: .:.. .: ...:::.:: . ..:   : ::  .... :    : . :
CCDS14 SHSTTASDQRLL-ASITPSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFIC
       90       100        110       120       130       140       

      180       190       200       210       220       230        
pF1KB9 EDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCA
       :.::.:::  ::  ::::: :.:...:::::....:::::.:::::::::::.:::::::
CCDS14 EECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCA
       150       160       170       180       190       200       

      240       250       260       270       280       290        
pF1KB9 DNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCK-NSN
       :.::::. : : .::.::...::::::: ::::..:::.:::  :: . ::::::: ..:
CCDS14 DEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTN
       210       220       230       240       250       260       

       300          310     
pF1KB9 TVCCKVPT--VP-PRNFEKPT
       ::: :. .  .: :.  ::  
CCDS14 TVCRKISSGSAPFPKAQEKSV
       270       280        

>>CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrX              (288 aa)
 initn: 851 init1: 727 opt: 885  Z-score: 685.5  bits: 134.9 E(32554): 7.3e-32
Smith-Waterman score: 885; 46.4% identity (69.9% similar) in 289 aa overlap (39-313:11-286)

       10        20        30        40        50        60        
pF1KB9 NGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLK
                                     ..: ..:.:. . .:.:.: :   : :  .
CCDS14                     MDAAVTDDFQQILPIEQLRSTHASNDYVERP---PAPCKQ
                                   10        20        30          

       70           80         90       100       110       120    
pF1KB9 PAPRPST---QHKHE-RLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRT
           ::     :: .  :  .:     :: . :: :.    :   : :...:.       
CCDS14 ALSSPSLIVQTHKSDWSLATMPTSL--PR-SLSQCHQLQPLPQHLSQSSIASS------M
        40        50        60           70        80              

          130       140       150       160          170           
pF1KB9 STSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKP---GELKPLSKEDLGL---HAYRC
       : :...:.:::: .:.. .: ...:::.:: . ..:   : ::  .... :    : . :
CCDS14 SHSTTASDQRLL-ASITPSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFIC
       90       100        110       120       130       140       

      180       190       200       210       220       230        
pF1KB9 EDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCA
       :.::.:::  ::  ::::: :.:...:::::....:::::.:::::::::::.:::::::
CCDS14 EECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCA
       150       160       170       180       190       200       

      240       250       260       270       280       290        
pF1KB9 DNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCK-NSN
       :.::::. : : .::.::...::::::: ::::..:::.:::  :: . ::::::: ..:
CCDS14 DEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTN
       210       220       230       240       250       260       

       300          310     
pF1KB9 TVCCKVPT--VP-PRNFEKPT
       ::: :. .  .: :.  ::  
CCDS14 TVCRKISSGSAPFPKAQEKSV
       270       280        

>>CCDS47296.1 SPRY4 gene_id:81848|Hs108|chr5              (299 aa)
 initn: 795 init1: 401 opt: 830  Z-score: 643.7  bits: 127.2 E(32554): 1.5e-29
Smith-Waterman score: 854; 45.5% identity (68.1% similar) in 279 aa overlap (34-305:31-287)

            10        20        30        40        50        60   
pF1KB9 RAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVP
                                     : . . .: .::... .  :.: ..:... 
CCDS47 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLA-
               10        20        30        40        50          

            70        80        90       100       110       120   
pF1KB9 RPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTR
          :  .:      :. :  : ::    :          ::   . .   .: ..: :. 
CCDS47 ---LTTGP------KRTR-GGAPELAPTP----------ARCDQDVTHHWISFSGRPSSV
         60               70                  80        90         

           130       140           150        160        170       
pF1KB9 TSTSSSSSEQRLLGSSFSSGPVADGI----IRVQPKS-ELKPGELK-PLSKEDLGLHAYR
       .:.::.::.:::: . ..  ::::      .:.:::  . .: .:: :    .:  :   
CCDS47 SSSSSTSSDQRLL-DHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLL
     100       110        120       130       140       150        

       180       190       200       210       220       230       
pF1KB9 CEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSN-DDEDN
       :: :::::::::. :: ::: :.:...::::::....::::.: :.:.::::.: ::: .
CCDS47 CEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS
      160       170       180       190       200       210        

        240       250       260       270       280       290      
pF1KB9 CADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNS
       :::.:::::.:.::.::: ::..:. :::: ::::: ::.:: :  :::. :::::::..
CCDS47 CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHT
      220       230       240       250       260       270        

        300       310       
pF1KB9 NTVCCKVPTVPPRNFEKPT  
       :.: ::. .            
CCDS47 NSVICKAASGDAKTSRPDKPF
      280       290         

>>CCDS4274.1 SPRY4 gene_id:81848|Hs108|chr5               (322 aa)
 initn: 795 init1: 401 opt: 830  Z-score: 643.3  bits: 127.2 E(32554): 1.6e-29
Smith-Waterman score: 854; 45.5% identity (68.1% similar) in 279 aa overlap (34-305:54-310)

            10        20        30        40        50        60   
pF1KB9 RAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVP
                                     : . . .: .::... .  :.: ..:... 
CCDS42 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLA-
            30        40        50        60        70        80   

            70        80        90       100       110       120   
pF1KB9 RPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTR
          :  .:      :. :  : ::    :          ::   . .   .: ..: :. 
CCDS42 ---LTTGP------KRTR-GGAPELAPTP----------ARCDQDVTHHWISFSGRPSSV
                      90        100                 110       120  

           130       140           150        160        170       
pF1KB9 TSTSSSSSEQRLLGSSFSSGPVADGI----IRVQPKS-ELKPGELK-PLSKEDLGLHAYR
       .:.::.::.:::: . ..  ::::      .:.:::  . .: .:: :    .:  :   
CCDS42 SSSSSTSSDQRLL-DHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLL
            130        140       150       160       170       180 

       180       190       200       210       220       230       
pF1KB9 CEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSN-DDEDN
       :: :::::::::. :: ::: :.:...::::::....::::.: :.:.::::.: ::: .
CCDS42 CEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS
             190       200       210       220       230       240 

        240       250       260       270       280       290      
pF1KB9 CADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNS
       :::.:::::.:.::.::: ::..:. :::: ::::: ::.:: :  :::. :::::::..
CCDS42 CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHT
             250       260       270       280       290       300 

        300       310       
pF1KB9 NTVCCKVPTVPPRNFEKPT  
       :.: ::. .            
CCDS42 NSVICKAASGDAKTSRPDKPF
             310       320  




315 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:29:14 2016 done: Fri Nov  4 19:29:14 2016
 Total Scan time:  3.020 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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