Result of FASTA (omim) for pF1KB9740
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9740, 517 aa
  1>>>pF1KB9740 517 - 517 aa - 517 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.8480+/-0.000406; mu= -5.6902+/- 0.025
 mean_var=359.1783+/-74.855, 0's: 0 Z-trim(122.9): 139  B-trim: 866 in 1/57
 Lambda= 0.067674
 statistics sampled from 41748 (41890) to 41748 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.491), width:  16
 Scan time: 10.600

The best scores are:                                      opt bits E(85289)
NP_998761 (OMIM: 609429) forkhead box protein N4 [ ( 517) 3606 365.9 1.6e-100
XP_011536224 (OMIM: 609429) PREDICTED: forkhead bo ( 518) 3594 364.7 3.7e-100
XP_016874307 (OMIM: 609429) PREDICTED: forkhead bo ( 474) 3068 313.3   1e-84
XP_011536225 (OMIM: 609429) PREDICTED: forkhead bo ( 314) 2135 222.1 1.9e-57
XP_016874308 (OMIM: 609429) PREDICTED: forkhead bo ( 377) 2125 221.2 4.4e-57
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436)  782 90.1 1.4e-17
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436)  782 90.1 1.4e-17
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436)  782 90.1 1.4e-17
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462)  782 90.1 1.5e-17
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648)  784 90.5 1.7e-17
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648)  784 90.5 1.7e-17
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648)  784 90.5 1.7e-17
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648)  784 90.5 1.7e-17
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649)  784 90.5 1.7e-17
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649)  784 90.5 1.7e-17
XP_016880719 (OMIM: 600838,601705) PREDICTED: fork ( 485)  698 81.9 4.6e-15
XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567)  697 81.9 5.5e-15
XP_016880720 (OMIM: 600838,601705) PREDICTED: fork ( 384)  692 81.3 5.8e-15
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468)  364 49.3 2.9e-05
NP_001078940 (OMIM: 602628) forkhead box protein N ( 490)  364 49.3   3e-05
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431)  356 48.5 4.7e-05
XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  356 48.5 4.7e-05
NP_859072 (OMIM: 615755) forkhead box protein R1 [ ( 292)  339 46.7 0.00011
XP_016873064 (OMIM: 615755) PREDICTED: forkhead bo ( 297)  337 46.5 0.00013
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378)  322 45.1 0.00043
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319)  320 44.9 0.00043
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501)  321 45.2 0.00056
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553)  316 44.7 0.00085
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570)  315 44.6 0.00093
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733)  315 44.7  0.0011
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403)  308 43.8  0.0012
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte  ( 439)  307 43.7  0.0013
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472)  307 43.8  0.0014
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420)  303 43.3  0.0017
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345)  297 42.7  0.0022
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457)  300 43.1  0.0022
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463)  300 43.1  0.0022
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350)  296 42.6  0.0024
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379)  296 42.6  0.0025
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376)  295 42.5  0.0027
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573)  298 43.0   0.003
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588)  298 43.0   0.003


>>NP_998761 (OMIM: 609429) forkhead box protein N4 [Homo  (517 aa)
 initn: 3606 init1: 3606 opt: 3606  Z-score: 1925.5  bits: 365.9 E(85289): 1.6e-100
Smith-Waterman score: 3606; 100.0% identity (100.0% similar) in 517 aa overlap (1-517:1-517)

               10        20        30        40        50        60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ
              430       440       450       460       470       480

              490       500       510       
pF1KB9 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       :::::::::::::::::::::::::::::::::::::
NP_998 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
              490       500       510       

>>XP_011536224 (OMIM: 609429) PREDICTED: forkhead box pr  (518 aa)
 initn: 3592 init1: 2775 opt: 3594  Z-score: 1919.1  bits: 364.7 E(85289): 3.7e-100
Smith-Waterman score: 3594; 99.8% identity (99.8% similar) in 518 aa overlap (1-517:1-518)

               10        20        30        40        50        60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB9 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB9 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL
              430       440       450       460       470       480

     480       490       500       510       
pF1KB9 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       ::::::::::::::::::::::::::::::::::::::
XP_011 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
              490       500       510        

>>XP_016874307 (OMIM: 609429) PREDICTED: forkhead box pr  (474 aa)
 initn: 3066 init1: 2775 opt: 3068  Z-score: 1642.1  bits: 313.3 E(85289): 1e-84
Smith-Waterman score: 3068; 99.5% identity (99.5% similar) in 443 aa overlap (76-517:32-474)

          50        60        70        80        90       100     
pF1KB9 LSWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPR
                                     : ::::::::::::::::::::::::::::
XP_016 SVTSPAQDGGSMSAILILCGAAGLGKGERRHKGALAGVADLHVGATPSPLLHGPAGMAPR
              10        20        30        40        50        60 

         110        120       130       140       150       160    
pF1KB9 GMPGLGPITGHRDS-MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG
       :::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMPGLGPITGHRDSQMSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG
              70        80        90       100       110       120 

          170       180       190       200       210       220    
pF1KB9 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK
             130       140       150       160       170       180 

          230       240       250       260       270       280    
pF1KB9 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK
             190       200       210       220       230       240 

          290       300       310       320       330       340    
pF1KB9 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS
             250       260       270       280       290       300 

          350       360       370       380       390       400    
pF1KB9 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP
             310       320       330       340       350       360 

          410       420       430       440       450       460    
pF1KB9 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG
             370       380       390       400       410       420 

          470       480       490       500       510       
pF1KB9 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
             430       440       450       460       470    

>>XP_011536225 (OMIM: 609429) PREDICTED: forkhead box pr  (314 aa)
 initn: 2159 init1: 1311 opt: 2135  Z-score: 1152.2  bits: 222.1 E(85289): 1.9e-57
Smith-Waterman score: 2135; 96.5% identity (98.1% similar) in 315 aa overlap (1-314:1-314)

               10        20        30        40        50        60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
       : :  ...: . :.:                                             
XP_011 PGEETEVLSVQ-EAC                                             
              310                                                  

>>XP_016874308 (OMIM: 609429) PREDICTED: forkhead box pr  (377 aa)
 initn: 2154 init1: 1306 opt: 2125  Z-score: 1145.8  bits: 221.2 E(85289): 4.4e-57
Smith-Waterman score: 2134; 81.3% identity (86.2% similar) in 390 aa overlap (1-388:1-376)

               10        20        30        40        50        60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
              250       260       270       280       290       300

     300       310       320        330       340       350        
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEA-PVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQS
       : :     : : ..  .    :. .. :. :.:  . :            .:. : .   
XP_016 PGEGRTARSARTHTHTHTHTHGRGRTWPTSTRAWPTLV------------KPMHTHAHTH
              310       320       330                   340        

      360       370       380       390       400       410        
pF1KB9 VPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV
          :  ..  .:   .  .:.  :: :. :                              
XP_016 KYAH--THKYTHTHTEEEGPGCHPPEHGQPQ                             
      350         360       370                                    

>>XP_011523670 (OMIM: 600838,601705) PREDICTED: forkhead  (436 aa)
 initn: 922 init1: 735 opt: 782  Z-score: 436.4  bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)

     110       120       130       140         150       160       
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
                                     :.:  : ..    ::  :  :  : :  :.
XP_011                            MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
                                          10        20        30   

       170       180       190       200       210       220       
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
            :   ..: ..: . :   .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
            40        50        60        70        80        90   

       230       240       250       260       270       280       
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
       :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
           100       110       120       130       140       150   

       290       300       310              320        330         
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
       ::  :...:::.:::::.::.:. :.       :  ::  :  :  :.   :      :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
           160       170       180       190       200       210   

     340         350       360                           370       
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
          : . .: . ::. : .  .:       :: .              ::..::      
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
           220       230       240       250       260       270   

               380       390       400       410       420         
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
        .: ::: ::.::: :.   :.    : ::  :.  : .  . :..:..::..::. :: 
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
           280       290          300         310       320        

     430       440       450       460                             
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
       .::::::..::....:: :   ..:: . ..                     ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
      330       340       350       360       370       380        

       470       480       490       500       510       
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       .::::  .. ::..: ::.:.                             
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 
      390        400       410       420       430       

>>XP_011523671 (OMIM: 600838,601705) PREDICTED: forkhead  (436 aa)
 initn: 922 init1: 735 opt: 782  Z-score: 436.4  bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)

     110       120       130       140         150       160       
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
                                     :.:  : ..    ::  :  :  : :  :.
XP_011                            MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
                                          10        20        30   

       170       180       190       200       210       220       
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
            :   ..: ..: . :   .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
            40        50        60        70        80        90   

       230       240       250       260       270       280       
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
       :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
           100       110       120       130       140       150   

       290       300       310              320        330         
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
       ::  :...:::.:::::.::.:. :.       :  ::  :  :  :.   :      :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
           160       170       180       190       200       210   

     340         350       360                           370       
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
          : . .: . ::. : .  .:       :: .              ::..::      
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
           220       230       240       250       260       270   

               380       390       400       410       420         
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
        .: ::: ::.::: :.   :.    : ::  :.  : .  . :..:..::..::. :: 
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
           280       290          300         310       320        

     430       440       450       460                             
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
       .::::::..::....:: :   ..:: . ..                     ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
      330       340       350       360       370       380        

       470       480       490       500       510       
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       .::::  .. ::..: ::.:.                             
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 
      390        400       410       420       430       

>>XP_011523672 (OMIM: 600838,601705) PREDICTED: forkhead  (436 aa)
 initn: 922 init1: 735 opt: 782  Z-score: 436.4  bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)

     110       120       130       140         150       160       
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
                                     :.:  : ..    ::  :  :  : :  :.
XP_011                            MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
                                          10        20        30   

       170       180       190       200       210       220       
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
            :   ..: ..: . :   .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
            40        50        60        70        80        90   

       230       240       250       260       270       280       
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
       :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
           100       110       120       130       140       150   

       290       300       310              320        330         
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
       ::  :...:::.:::::.::.:. :.       :  ::  :  :  :.   :      :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
           160       170       180       190       200       210   

     340         350       360                           370       
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
          : . .: . ::. : .  .:       :: .              ::..::      
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
           220       230       240       250       260       270   

               380       390       400       410       420         
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
        .: ::: ::.::: :.   :.    : ::  :.  : .  . :..:..::..::. :: 
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
           280       290          300         310       320        

     430       440       450       460                             
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
       .::::::..::....:: :   ..:: . ..                     ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
      330       340       350       360       370       380        

       470       480       490       500       510       
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       .::::  .. ::..: ::.:.                             
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 
      390        400       410       420       430       

>>XP_011523669 (OMIM: 600838,601705) PREDICTED: forkhead  (462 aa)
 initn: 922 init1: 735 opt: 782  Z-score: 436.0  bits: 90.1 E(85289): 1.5e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:30-434)

     110       120       130       140         150       160       
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
                                     :.:  : ..    ::  :  :  : :  :.
XP_011  MEKSSRDTQQGSEVKVKPPVLESGAGMFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
                10        20        30        40        50         

       170       180       190       200       210       220       
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
            :   ..: ..: . :   .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
      60        70        80        90       100       110         

       230       240       250       260       270       280       
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
       :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
     120       130       140       150       160       170         

       290       300       310              320        330         
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
       ::  :...:::.:::::.::.:. :.       :  ::  :  :  :.   :      :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
     180       190       200       210       220       230         

     340         350       360                           370       
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
          : . .: . ::. : .  .:       :: .              ::..::      
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
     240       250       260       270       280       290         

               380       390       400       410       420         
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
        .: ::: ::.::: :.   :.    : ::  :.  : .  . :..:..::..::. :: 
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
     300       310       320            330       340       350    

     430       440       450       460                             
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
       .::::::..::....:: :   ..:: . ..                     ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
          360       370       380       390       400       410    

       470       480       490       500       510       
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
       .::::  .. ::..: ::.:.                             
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 
          420        430       440       450       460   

>>XP_005258103 (OMIM: 600838,601705) PREDICTED: forkhead  (648 aa)
 initn: 922 init1: 735 opt: 784  Z-score: 435.2  bits: 90.5 E(85289): 1.7e-17
Smith-Waterman score: 955; 41.7% identity (59.5% similar) in 482 aa overlap (77-488:152-620)

         50        60        70        80         90       100     
pF1KB9 SWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVG-ATPSPLLHGPAGMAP-
                                     :: : .  .. :  :    .: : .. :  
XP_005 PFHPYKRPFHEDVFPEAETTLALKGHSFKTPGPLEAFEEIPVDVAEAEAFLPGFSAEAWC
             130       140       150       160       170       180 

              110       120       130           140       150      
pF1KB9 RGMPG----LGPITGHRDSMSQFPVGGQPSSGL--QDPP--HLYSPATQPQFPLPPGAQQ
        :.:      :: .   .   . ::  . ..:.   .::  :.:  ..:: :      : 
XP_005 NGLPYPSQEHGPQVLGSEVKVKPPVL-ESGAGMFCYQPPLQHMYC-SSQPPF-----HQY
             190       200        210       220        230         

        160       170       180       190       200       210      
pF1KB9 CPPVGLYGPPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPV
        :  : :  :.     :   ..: ..: . :   .:::::::: :: :::::::::::::
XP_005 SPGGGSYPIPYLGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPV
          240       250       260       270       280       290    

        220       230       240       250       260       270      
pF1KB9 SEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARID
       ::::.:: ::::::::::::::::::::::::::::::::: ..::::::::::: :.::
XP_005 SEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKID
          300       310       320       330       340       350    

        280       290       300       310              320         
pF1KB9 KMEEEMHKWKRKDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVL
       ::.::..::::::  :...:::.:::::.::.:. :.       :  ::  :  :  :. 
XP_005 KMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLA
          360       370       380       390       400       410    

      330       340         350       360                          
pF1KB9 THATTVAVAHGCL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------Q
         :      :.   : . .: . ::. : .  .:       :: .              :
XP_005 PPAGLSPPLHSLHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQ
          420       430       440       450       460       470    

        370               380       390       400       410        
pF1KB9 PQAHL-------AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV
       :..::       .: ::: ::.::: :.   :.    : ::  :.  : .  . :..:..
XP_005 PDGHLELRAQPGTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDL
          480       490       500          510         520         

      420       430       440       450       460                  
pF1KB9 DALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDL------------------
       ::..::. :: .::::::..::....:: :   ..:: . ..                  
XP_005 DAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTE
     530       540       550       560       570       580         

                  470       480       490       500       510      
pF1KB9 ---GASGLT-PASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIAL
          ::. :. :.::::  .. ::..: ::.:.                            
XP_005 TGSGAGDLAAPGSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
     590       600        610       620       630       640        

        
pF1KB9 L




517 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:38:04 2016 done: Fri Nov  4 18:38:06 2016
 Total Scan time: 10.600 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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