Result of FASTA (omim) for pF1KB9652
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9652, 317 aa
  1>>>pF1KB9652 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0046+/-0.00029; mu= 9.6138+/- 0.018
 mean_var=144.8902+/-30.744, 0's: 0 Z-trim(121.4): 178  B-trim: 331 in 1/59
 Lambda= 0.106550
 statistics sampled from 37683 (37920) to 37683 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.445), width:  16
 Scan time:  8.670

The best scores are:                                      opt bits E(85289)
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 2167 344.1 2.3e-94
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446)  923 152.9 1.1e-36
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391)  780 130.9 4.1e-30
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276)  620 106.2   8e-23
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240)  601 103.2 5.5e-22
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233)  499 87.5 2.8e-17
NP_071899 (OMIM: 610928,613674) transcription fact ( 414)  466 82.7 1.5e-15
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446)  433 77.6 5.2e-14
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204)  424 76.0 7.5e-14
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384)  422 75.9 1.5e-13
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315)  415 74.7 2.7e-13
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466)  412 74.4   5e-13
NP_003099 (OMIM: 600898,615866) transcription fact ( 441)  410 74.1 5.9e-13
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509)  407 73.7 9.1e-13
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474)  402 72.9 1.5e-12
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388)  386 70.3   7e-12
NP_821078 (OMIM: 604975,616803) transcription fact ( 377)  338 63.0 1.1e-09
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415)  338 63.0 1.2e-09
NP_001248343 (OMIM: 604975,616803) transcription f ( 642)  338 63.2 1.7e-09
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715)  338 63.2 1.8e-09
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715)  338 63.2 1.8e-09
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715)  338 63.2 1.8e-09
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715)  338 63.2 1.8e-09
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716)  338 63.2 1.8e-09
NP_001317714 (OMIM: 604975,616803) transcription f ( 728)  338 63.2 1.9e-09
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729)  338 63.2 1.9e-09
NP_694534 (OMIM: 604975,616803) transcription fact ( 750)  338 63.2 1.9e-09
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750)  338 63.2 1.9e-09
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751)  338 63.2 1.9e-09
NP_001248344 (OMIM: 604975,616803) transcription f ( 753)  338 63.2 1.9e-09
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754)  338 63.2 1.9e-09
NP_008871 (OMIM: 604975,616803) transcription fact ( 763)  338 63.2 1.9e-09
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764)  338 63.2 1.9e-09
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792)  338 63.2   2e-09
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793)  338 63.2   2e-09
NP_001139283 (OMIM: 607257) transcription factor S ( 801)  329 61.9 5.2e-09
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804)  329 61.9 5.2e-09
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808)  329 61.9 5.2e-09
NP_001139291 (OMIM: 607257) transcription factor S ( 841)  329 61.9 5.4e-09
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621)  316 59.8 1.7e-08
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622)  316 59.8 1.7e-08
XP_005258732 (OMIM: 612082) PREDICTED: protein cap (1605)  311 59.3 5.9e-08


>>NP_003097 (OMIM: 184429,189960,206900) transcription f  (317 aa)
 initn: 2167 init1: 2167 opt: 2167  Z-score: 1815.1  bits: 344.1 E(85289): 2.3e-94
Smith-Waterman score: 2167; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)

               10        20        30        40        50        60
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
              250       260       270       280       290       300

              310       
pF1KB9 GPVPGTAINGTLPLSHM
       :::::::::::::::::
NP_003 GPVPGTAINGTLPLSHM
              310       

>>NP_005625 (OMIM: 300123,312000,313430) transcription f  (446 aa)
 initn: 1183 init1: 656 opt: 923  Z-score: 779.6  bits: 152.9 E(85289): 1.1e-36
Smith-Waterman score: 1153; 52.8% identity (74.0% similar) in 377 aa overlap (1-317:76-446)

                                             10                 20 
pF1KB9                               MYNMMETELKPP-G-PQQTSG-------GG
                                     ::...::::: : : : :..:       ::
NP_005 ESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGG
          50        60        70        80        90       100     

              30                      40        50        60       
pF1KB9 GGNSTAAAAGGNQKNS--------------PDRVKRPMNAFMVWSRGQRRKMAQENPKMH
       .:.:.: :::: ....               :::::::::::::::::::::: ::::::
NP_005 AGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMH
         110       120       130       140       150       160     

        70        80        90       100       110       120       
pF1KB9 NSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTL
       ::::::::::.::::...::::::::::::::.::::.::::::::::::::.:::::.:
NP_005 NSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSL
         170       180       190       200       210       220     

       130       140       150          160       170       180    
pF1KB9 PGGLLAPGGNSMASGVGVGAGLGA---GVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHP
       :.::: ::. . :......:. ..   ::.::.:.:.:.:::.::.::..:.:::: : :
NP_005 PSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPP
         230       240       250       260       270       280     

          190        200       210                      220        
pF1KB9 GLNAHGAAQ-MQPMHRYDVSALQYNSMT--SSQTYMN---------G----SPTYSMS--
       ....      . ::::::...:::. :   ..:.:::         :    .:. . .  
NP_005 SMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAA
         290       300       310       320       330       340     

          230                240       250       260       270     
pF1KB9 --YSQQ---------GTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMIS
         :.::         .. .:.:: :::::::: :: ::..  .:::.  :  ::::::::
NP_005 AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAI--ASHSQRACL-GDLRDMIS
         350       360       370       380         390        400  

          280          290        300       310       
pF1KB9 MYLP-GAEVPEPAAP---SRLH-MSQHYQSGPVPGTAINGTLPLSHM
       :::: :... . :.:   .::: . ::::..   :::.:::.::.:.
NP_005 MYLPPGGDAADAASPLPGGRLHGVHQHYQGA---GTAVNGTVPLTHI
            410       420       430          440      

>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H  (391 aa)
 initn: 1037 init1: 728 opt: 780  Z-score: 661.6  bits: 130.9 E(85289): 4.1e-30
Smith-Waterman score: 1095; 54.0% identity (69.7% similar) in 363 aa overlap (1-288:1-358)

                10                 20        30        40        50
pF1KB9 MYNMM-ETELKPPGPQQT---------SGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMV
       ::.:: ::.:. ::  :.         .:::::.. ....::. : . ::::::::::::
NP_005 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB9 WSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKY
       ::::::::::::::::::::::::::::::..::.:::::::::::::::::::::::::
NP_005 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY
               70        80        90       100       110       120

              120       130           140       150                
pF1KB9 RPRRKTKTLMKKDKYTLPGGLLAPG----GNSMASGVGVGAGLGAGVNQRMDS-------
       :::::::::.:::::.: ::::: :    : ..: :::::.: .:.:.::..:       
NP_005 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG-AAAVGQRLESPGGAAGG
              130       140       150       160        170         

      160       170                   180            190           
pF1KB9 -YAHMNGWSNGSY-----------SMMQD-QLGYPQHPGL-----NAHGAAQM-------
        :::.:::.::.:           .:::. ::.: ::::      .:: :          
NP_005 GYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAH
     180       190       200       210       220       230         

              200       210       220             230              
pF1KB9 ----QPMHRYDVSALQYNSMTSSQTYMNGSPT------YSMSYSQQGTPGMA--------
           :::::::..::::. ...:: ::..::.      :. . .  .. : :        
NP_005 PHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAA
     240       250       260       270       280       290         

                   240       250       260       270       280     
pF1KB9 -----------LGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPE
                  ::..::.:::: :.:::   . .::::::  ::::.:::::::..:  .
NP_005 AAAAAAASSGALGALGSLVKSEPSGSPP---APAHSRAPCP-GDLREMISMYLPAGEGGD
     300       310       320          330        340       350     

         290       300       310           
pF1KB9 PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM    
       :::                                 
NP_005 PAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
         360       370       380       390 

>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [  (276 aa)
 initn: 624 init1: 569 opt: 620  Z-score: 530.7  bits: 106.2 E(85289): 8e-23
Smith-Waterman score: 620; 43.0% identity (62.9% similar) in 272 aa overlap (39-304:6-269)

       10        20        30        40        50        60        
pF1KB9 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
                                     :.:::::::::::::.::::::::::::::
NP_009                          MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHN
                                        10        20        30     

       70        80        90       100       110       120        
pF1KB9 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP
       ::::::::::::::.:.::::::::::::::.::::::::::::::: :::.::::...:
NP_009 SEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFP
          40        50        60        70        80        90     

           130       140       150       160       170       180   
pF1KB9 -----GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQH
            ::.      .. .:.:. :: :.:.    .:       . .. .    .. .:: 
NP_009 VPYGLGGVADAEHPALKAGAGLHAGAGGGLVP--ESLLANPEKAAAAAAAAAARVFFPQS
         100       110       120         130       140       150   

           190       200       210       220       230       240   
pF1KB9 PGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM-GS
        .  : .::       :..  :  ..:.  ..  .: : :.   :. : :  . :.. :.
NP_009 AAAAAAAAAAAAAGSPYSLLDLG-SKMAEISSSSSGLP-YA---SSLGYPTAGAGAFHGA
           160       170        180       190           200        

            250       260       270       280       290       300  
pF1KB9 VVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGP
       .. . :...     . ::  .: . : .        :.  .  : :   :    . :  :
NP_009 AAAAAAAAAAAGGHTHSHP-SPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDP
      210       220        230       240       250       260       

            310       
pF1KB9 VPGTAINGTLPLSHM
        :             
NP_009 YPAAYAAAL      
       270            

>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [  (240 aa)
 initn: 626 init1: 574 opt: 601  Z-score: 515.7  bits: 103.2 E(85289): 5.5e-22
Smith-Waterman score: 601; 48.6% identity (69.5% similar) in 220 aa overlap (39-254:6-216)

       10        20        30        40        50        60        
pF1KB9 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
                                     :..:::::::::::::::::::::::::::
NP_004                          MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN
                                        10        20        30     

       70        80        90       100       110       120        
pF1KB9 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP
       ::::::::::::::::.::::.::::::::: ::::::::::::::: :.:.:::.:..:
NP_004 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP
          40        50        60        70        80        90     

      130       140       150       160       170       180        
pF1KB9 GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNA
          :.      :.:. :::. :  ..    . : .   ... ::...     : . . .:
NP_004 LPYLGDTDPLKAAGLPVGASDGL-LSAPEKARAFLPP-ASAPYSLLD-----PAQFSSSA
         100       110        120       130        140             

      190       200       210       220           230       240    
pF1KB9 HGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS---PT-YSMSYSQQGTPGMALGSMGSVV
              : :   ..:: : :  . :.   ::   :. .. .. .  .::...   . ..
NP_004 IQKMGEVP-HTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVV-PCNCTA
      150        160       170       180       190       200       

          250       260       270       280       290       300    
pF1KB9 KSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVP
        : .. .:::                                                  
NP_004 WSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM                          
        210       220       230       240                          

>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens]  (233 aa)
 initn: 477 init1: 458 opt: 499  Z-score: 431.2  bits: 87.5 E(85289): 2.8e-17
Smith-Waterman score: 499; 43.9% identity (64.5% similar) in 214 aa overlap (13-221:28-227)

                              10        20        30         40    
pF1KB9                MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSP-DRVKRP
                                  :::.  :.:    . :: :    . : ..::::
NP_008 MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAG----SPAAPG----TLPLEKVKRP
               10        20        30            40            50  

           50        60        70        80        90       100    
pF1KB9 MNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKE
       :::::::: .:::.:::.:::::::::::::::.::::.: :::::..::::::: :...
NP_008 MNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRD
             60        70        80        90       100       110  

          110       120        130       140       150       160   
pF1KB9 HPDYKYRPRRKTKTLMKKDKYTLPG-GLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHM
       .::::::::::.:.     .    : : :: ::   . : ..    . : . :  ::.  
NP_008 YPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQP-SRGFGYRPPSYS--
            120       130       140       150        160           

           170       180          190       200       210       220
pF1KB9 NGWSNGSYSMMQDQLGYPQH---PGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS
       ...  :::.  . .:  :.    :  . .  ... : . .    :  .: :  .  . :.
NP_008 TAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTH---YLPPGSPTPYNPPLAGA
     170       180       190       200          210       220      

              230       240       250       260       270       280
pF1KB9 PTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPG
       :                                                           
NP_008 PMPLTHL                                                     
        230                                                        

>>NP_071899 (OMIM: 610928,613674) transcription factor S  (414 aa)
 initn: 467 init1: 398 opt: 466  Z-score: 400.4  bits: 82.7 E(85289): 1.5e-15
Smith-Waterman score: 468; 31.7% identity (56.7% similar) in 312 aa overlap (9-305:36-331)

                                     10        20        30        
pF1KB9                       MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSP
                                     :.: : ....: . .:: : :..... .. 
NP_071 AGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGE
          10        20        30        40        50        60     

       40        50        60        70        80        90        
pF1KB9 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR
       .:..:::::::::.. .:...::.:: .::.:.:: ::  :: :. .:::::..::.:::
NP_071 SRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLR
          70        80        90       100       110       120     

      100       110       120          130       140       150     
pF1KB9 ALHMKEHPDYKYRPRRKTKTLMKKDKYTLPG---GLLAPGGNSMASGVGVGAGLGAGVNQ
       . ::..::.:::::::. .  .:. : .  :   ::  : . ...   :  :  : :.. 
NP_071 VQHMQDHPNYKYRPRRRKQ--VKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQF
         130       140         150       160       170       180   

         160               170        180       190       200      
pF1KB9 RMDSYA--------HMNGWSNGSYSMMQDQL-GYPQHPGLNAHGAAQMQPMHRYDVSALQ
         ...         ::.:      :.    : :::  :      . . .:.   : .   
NP_071 PEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPL-P------TPDTSPLDGVDPDPAF
           190       200       210        220             230      

        210       220       230       240        250       260     
pF1KB9 YNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSE-ASSSPPVVTSSSHSRAPC
       . .   ..    :. .:..  .  : :    : :   .  : :. : : .       :: 
NP_071 FAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLL------APP
        240       250       260       270       280             290

         270       280         290       300       310             
pF1KB9 QAGDLRDMISMYLPGAEVPE--PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM      
       .:  .  . .:  :::   .     :.. :. :: .  : ::                  
NP_071 SALHVY-YGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPS
               300       310       320       330       340         

NP_071 QPAELLGEVDRTEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYC
     350       360       370       380       390       400         

>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H  (446 aa)
 initn: 387 init1: 387 opt: 433  Z-score: 372.6  bits: 77.6 E(85289): 5.2e-14
Smith-Waterman score: 441; 31.5% identity (56.0% similar) in 327 aa overlap (14-313:85-396)

                                10        20        30        40   
pF1KB9                  MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKR
                                     :. . ::::         :  : .: .:::
NP_055 DPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGG---------GALKAKP-HVKR
           60        70        80        90                100     

            50        60        70        80        90       100   
pF1KB9 PMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMK
       ::::::::... :::.:.. :..::.:.:: ::  :.::::.:::::..::.:::. : :
NP_055 PMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKK
          110       120       130       140       150       160    

           110       120       130         140       150       160 
pF1KB9 EHPDYKYRPRRKTKTLMKKDKYTLPGGLLAP--GGNSMASGVGVGAGLGAGVNQRMDSYA
       .::::::.:::. :.     . .  :. :.:  ::... .   . :::: : ... :  .
NP_055 DHPDYKYQPRRR-KSAKAGHSDSDSGAELGPHPGGGAVYK---AEAGLGDG-HHHGDHTG
          170        180       190       200          210          

             170       180       190             200       210     
pF1KB9 HMNGWSNGSYSMMQDQLGYPQHPGLNAHG------AAQMQPMHRYDVSALQYNSMTSSQT
       . .:  .   .   .      .: :. .:      . :   .   :.: :. . : . ..
NP_055 QTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDA
     220       230       240       250       260       270         

                  220              230        240       250        
pF1KB9 --------YMN-GSPT-------YSMSYSQQG-TPGMALGSMGSVVKSEASSSPPVVTSS
               :.  :.:.       :. .: . : .:  :  :  :.  : . ..::    .
NP_055 FDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIK
     280       290       300       310       320       330         

      260       270         280       290       300       310      
pF1KB9 SHSRAPCQAGDLRDMISMY--LPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSH
       ... .: . ::       :    :     ::::.    ... . : . ...  :. :   
NP_055 TEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYA
     340       350       360       370       380       390         

                                                      
pF1KB9 M                                              
                                                      
NP_055 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
     400       410       420       430       440      

>>NP_003131 (OMIM: 400044,400045,480000) sex-determining  (204 aa)
 initn: 434 init1: 416 opt: 424  Z-score: 369.6  bits: 76.0 E(85289): 7.5e-14
Smith-Waterman score: 439; 45.6% identity (69.6% similar) in 171 aa overlap (31-200:49-198)

               10        20        30         40        50         
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQK-NSPDRVKRPMNAFMVWSRGQRRKM
                                     : :.: :  ::::::::::.:::: :::::
NP_003 PAVQENIPALRRSSSFLCTESCNSKYQCETGENSKGNVQDRVKRPMNAFIVWSRDQRRKM
       20        30        40        50        60        70        

      60        70        80        90       100       110         
pF1KB9 AQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTL
       : :::.:.::::::.:: .::.:.:.:: ::..::..:.:.: ...:.::::::::.: .
NP_003 ALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAK-M
       80        90       100       110       120       130        

     120       130       140       150       160       170         
pF1KB9 MKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLG
       . :.   ::    :  .. . : :            ..:.  . .  .....: :. :::
NP_003 LPKNCSLLP----ADPASVLCSEV------------QLDNRLYRDDCTKATHSRMEHQLG
       140           150                   160       170       180 

     180       190       200       210       220       230         
pF1KB9 YPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGS
       .   : .::  :.. :   ::                                       
NP_003 H--LPPINA--ASSPQQRDRYSHWTKL                                 
                 190       200                                     

>>NP_060889 (OMIM: 137940,601618,607823) transcription f  (384 aa)
 initn: 439 init1: 383 opt: 422  Z-score: 364.3  bits: 75.9 E(85289): 1.5e-13
Smith-Waterman score: 422; 46.5% identity (74.4% similar) in 129 aa overlap (11-135:51-176)

                                   10        20          30        
pF1KB9                     MYNMMETELKPPGPQQTSGGGG--GNSTAAAAGGNQKNSP
                                     ::.::..   .   :    . :: ..... 
NP_060 AWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAA
               30        40        50        60        70        80

         40        50        60        70        80        90      
pF1KB9 D--RVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKR
       :  :..:::::::::.. .:...::.:: .::. .:: ::  :: :. .:::::..::.:
NP_060 DESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAER
               90       100       110       120       130       140

        100       110       120       130       140       150      
pF1KB9 LRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQR
       ::. :...::.:::::::: ..  .: .   :: :: ::                     
NP_060 LRVQHLRDHPNYKYRPRRKKQA--RKARRLEPG-LLLPGLAPPQPPPEPFPAASGSARAF
              150       160         170        180       190       

        160       170       180       190       200       210      
pF1KB9 MDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTY
                                                                   
NP_060 RELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRD
       200       210       220       230       240       250       




317 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:58:41 2016 done: Fri Nov  4 17:58:42 2016
 Total Scan time:  8.670 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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