Result of FASTA (omim) for pF1KB9625
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9625, 133 aa
  1>>>pF1KB9625 133 - 133 aa - 133 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5667+/-0.000267; mu= 8.9107+/- 0.017
 mean_var=173.7233+/-34.763, 0's: 0 Z-trim(125.6): 54  B-trim: 2653 in 1/54
 Lambda= 0.097307
 statistics sampled from 49778 (49841) to 49778 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.867), E-opt: 0.2 (0.584), width:  16
 Scan time:  5.410

The best scores are:                                      opt bits E(85289)
NP_005589 (OMIM: 162360) helix-loop-helix protein  ( 133)  903 136.7   1e-32
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135)  487 78.3   4e-15
NP_005590 (OMIM: 162361) helix-loop-helix protein  ( 135)  487 78.3   4e-15
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172)  202 38.5  0.0052
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172)  202 38.5  0.0052
XP_005268588 (OMIM: 602406) PREDICTED: heart- and  ( 214)  202 38.6   0.006
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215)  202 38.6   0.006
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206)  200 38.3  0.0071
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331)  202 38.8  0.0079
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331)  202 38.8  0.0079
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331)  202 38.8  0.0079
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  202 38.8  0.0079
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331)  202 38.8  0.0079
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331)  202 38.8  0.0079
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108)  194 37.1  0.0084
NP_005089 (OMIM: 603628) musculin [Homo sapiens]   ( 206)  198 38.0  0.0086
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280)  200 38.4  0.0086
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302)  200 38.5   0.009
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351)  200 38.5    0.01


>>NP_005589 (OMIM: 162360) helix-loop-helix protein 1 [H  (133 aa)
 initn: 903 init1: 903 opt: 903  Z-score: 708.2  bits: 136.7 E(85289): 1e-32
Smith-Waterman score: 903; 100.0% identity (100.0% similar) in 133 aa overlap (1-133:1-133)

               10        20        30        40        50        60
pF1KB9 MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA
               70        80        90       100       110       120

              130   
pF1KB9 ICYISYLNHVLDV
       :::::::::::::
NP_005 ICYISYLNHVLDV
              130   

>>NP_001104531 (OMIM: 162361) helix-loop-helix protein 2  (135 aa)
 initn: 478 init1: 461 opt: 487  Z-score: 392.5  bits: 78.3 E(85289): 4e-15
Smith-Waterman score: 487; 64.3% identity (75.5% similar) in 143 aa overlap (1-133:1-135)

                10         20           30             40        50
pF1KB9 MMLNSD-TMELDLPPT-HSETES-GFSDCG--GGAG---P--DGAGPGGPGGGQARGPEP
       :::. : . . : : . ::. :: : .:    :...   :  .. : :  :.  :  :.:
NP_001 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB9 GEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
               :.:::::.:::::::::::.::::::::::::::::::::::::::::::::
NP_001 --------QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
                       70        80        90       100       110  

              120       130   
pF1KB9 LSKIEILRLAICYISYLNHVLDV
       :::::::::::::::::::::::
NP_001 LSKIEILRLAICYISYLNHVLDV
            120       130     

>>NP_005590 (OMIM: 162361) helix-loop-helix protein 2 [H  (135 aa)
 initn: 478 init1: 461 opt: 487  Z-score: 392.5  bits: 78.3 E(85289): 4e-15
Smith-Waterman score: 487; 64.3% identity (75.5% similar) in 143 aa overlap (1-133:1-135)

                10         20           30             40        50
pF1KB9 MMLNSD-TMELDLPPT-HSETES-GFSDCG--GGAG---P--DGAGPGGPGGGQARGPEP
       :::. : . . : : . ::. :: : .:    :...   :  .. : :  :.  :  :.:
NP_005 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB9 GEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
               :.:::::.:::::::::::.::::::::::::::::::::::::::::::::
NP_005 --------QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
                       70        80        90       100       110  

              120       130   
pF1KB9 LSKIEILRLAICYISYLNHVLDV
       :::::::::::::::::::::::
NP_005 LSKIEILRLAICYISYLNHVLDV
            120       130     

>>NP_001277335 (OMIM: 187040,613065) T-cell acute lympho  (172 aa)
 initn: 200 init1: 200 opt: 202  Z-score: 175.0  bits: 38.5 E(85289): 0.0052
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (82-132:35-85)

              60        70        80        90       100       110 
pF1KB9 EPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
                                     .::: : .  : ::::::::.:: ::::::
NP_001 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
           10        20        30        40        50        60    

             120       130                                         
pF1KB9 SKIEILRLAICYISYLNHVLDV                                      
       :: ::::::. ::..: ..:.                                       
NP_001 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
           70        80        90       100       110       120    

>>XP_016857682 (OMIM: 187040,613065) PREDICTED: T-cell a  (172 aa)
 initn: 200 init1: 200 opt: 202  Z-score: 175.0  bits: 38.5 E(85289): 0.0052
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (82-132:35-85)

              60        70        80        90       100       110 
pF1KB9 EPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
                                     .::: : .  : ::::::::.:: ::::::
XP_016 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
           10        20        30        40        50        60    

             120       130                                         
pF1KB9 SKIEILRLAICYISYLNHVLDV                                      
       :: ::::::. ::..: ..:.                                       
XP_016 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
           70        80        90       100       110       120    

>>XP_005268588 (OMIM: 602406) PREDICTED: heart- and neur  (214 aa)
 initn: 197 init1: 175 opt: 202  Z-score: 174.0  bits: 38.6 E(85289): 0.006
Smith-Waterman score: 211; 43.1% identity (65.1% similar) in 109 aa overlap (30-131:52-150)

                10        20        30            40          50   
pF1KB9  MMLNSDTMELDLPPTHSETESGFSDCGGGAGPD----GAGPGGPGGGQARGPE--PGE-
                                     :.::    :  :.. ... : ::.  ::. 
XP_005 MLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDARPGQS
              30        40        50        60        70        80 

             60        70        80        90       100       110  
pF1KB9 PGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLS
       :::  :. :.   :  ::....        .:: :.:..: ::::::. .:..: : :::
XP_005 PGR--LEALGG--RLGRRKGSG------PKKERRRTESINSAFAELRECIPNVPADTKLS
                90               100       110       120       130 

            120       130                                          
pF1KB9 KIEILRLAICYISYLNHVLDV                                       
       ::. ::::  ::.::  ::                                         
XP_005 KIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRELQHEGFPPALG
             140       150       160       170       180       190 

>>NP_004812 (OMIM: 602406) heart- and neural crest deriv  (215 aa)
 initn: 197 init1: 175 opt: 202  Z-score: 173.9  bits: 38.6 E(85289): 0.006
Smith-Waterman score: 211; 43.1% identity (65.1% similar) in 109 aa overlap (30-131:52-150)

                10        20        30            40          50   
pF1KB9  MMLNSDTMELDLPPTHSETESGFSDCGGGAGPD----GAGPGGPGGGQARGPE--PGE-
                                     :.::    :  :.. ... : ::.  ::. 
NP_004 MLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDARPGQS
              30        40        50        60        70        80 

             60        70        80        90       100       110  
pF1KB9 PGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLS
       :::  :. :.   :  ::....        .:: :.:..: ::::::. .:..: : :::
NP_004 PGR--LEALGG--RLGRRKGSG------PKKERRRTESINSAFAELRECIPNVPADTKLS
                90               100       110       120       130 

            120       130                                          
pF1KB9 KIEILRLAICYISYLNHVLDV                                       
       ::. ::::  ::.::  ::                                         
NP_004 KIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRELQQHEGFPPAL
             140       150       160       170       180       190 

>>XP_005259969 (OMIM: 151440) PREDICTED: protein lyl-1 i  (206 aa)
 initn: 216 init1: 194 opt: 200  Z-score: 172.6  bits: 38.3 E(85289): 0.0071
Smith-Waterman score: 200; 43.0% identity (65.6% similar) in 93 aa overlap (39-131:42-132)

       10        20        30        40        50        60        
pF1KB9 ELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRR
                                     ::.:  .  :      : .  .:.  : ..
XP_005 PLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRPSHCELDLAEGHQ
              20        30        40        50        60        70 

       70        80        90       100       110       120        
pF1KB9 RRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLN
        .... .  :   .::: : .  : ::::::::::: :::.:::: :.::::. ::..: 
XP_005 PQKVARRVFTN--SRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLV
              80          90       100       110       120         

      130                                                          
pF1KB9 HVLDV                                                       
       ..:                                                         
XP_005 RLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGG
     130       140       150       160       170       180         

>>NP_001277334 (OMIM: 187040,613065) T-cell acute lympho  (331 aa)
 initn: 277 init1: 200 opt: 202  Z-score: 171.8  bits: 38.8 E(85289): 0.0079
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (82-132:194-244)

              60        70        80        90       100       110 
pF1KB9 EPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
                                     .::: : .  : ::::::::.:: ::::::
NP_001 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
           170       180       190       200       210       220   

             120       130                                         
pF1KB9 SKIEILRLAICYISYLNHVLDV                                      
       :: ::::::. ::..: ..:.                                       
NP_001 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
           230       240       250       260       270       280   

>>NP_001277333 (OMIM: 187040,613065) T-cell acute lympho  (331 aa)
 initn: 277 init1: 200 opt: 202  Z-score: 171.8  bits: 38.8 E(85289): 0.0079
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (82-132:194-244)

              60        70        80        90       100       110 
pF1KB9 EPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
                                     .::: : .  : ::::::::.:: ::::::
NP_001 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
           170       180       190       200       210       220   

             120       130                                         
pF1KB9 SKIEILRLAICYISYLNHVLDV                                      
       :: ::::::. ::..: ..:.                                       
NP_001 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
           230       240       250       260       270       280   




133 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:47:28 2016 done: Fri Nov  4 17:47:29 2016
 Total Scan time:  5.410 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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