Result of FASTA (omim) for pF1KB9572
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9572, 788 aa
  1>>>pF1KB9572 788 - 788 aa - 788 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.6798+/-0.000409; mu= 0.7427+/- 0.025
 mean_var=242.7117+/-49.836, 0's: 0 Z-trim(118.7): 90  B-trim: 423 in 2/55
 Lambda= 0.082324
 statistics sampled from 31872 (31962) to 31872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.375), width:  16
 Scan time: 11.320

The best scores are:                                      opt bits E(85289)
XP_011542935 (OMIM: 605301) PREDICTED: transformin ( 788) 5129 622.9 1.6e-177
XP_011542934 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122
XP_005273682 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122
XP_011542933 (OMIM: 605301) PREDICTED: transformin ( 817) 3596 440.8 1.1e-122
XP_005273685 (OMIM: 605301) PREDICTED: transformin ( 789) 3222 396.4 2.5e-109
XP_005273686 (OMIM: 605301) PREDICTED: transformin ( 781) 3221 396.3 2.7e-109
XP_011542936 (OMIM: 605301) PREDICTED: transformin ( 776) 3196 393.3 2.1e-108
NP_006274 (OMIM: 605301) transforming acidic coile ( 805) 3166 389.8 2.5e-107
XP_016869257 (OMIM: 605301) PREDICTED: transformin ( 748) 2822 348.9 4.7e-95
XP_016869258 (OMIM: 605301) PREDICTED: transformin ( 740) 2821 348.8 5.1e-95
XP_016869255 (OMIM: 605301) PREDICTED: transformin ( 777) 2792 345.3 5.8e-94
XP_016869256 (OMIM: 605301) PREDICTED: transformin ( 769) 2791 345.2 6.2e-94
XP_005273687 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76
XP_016869259 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76
XP_011542937 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76
XP_016869260 (OMIM: 605301) PREDICTED: transformin ( 622) 2288 285.4 5.1e-76
XP_016869267 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65
XP_016869265 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65
NP_001317450 (OMIM: 605301) transforming acidic co ( 581) 1996 250.7 1.3e-65
XP_016869266 (OMIM: 605301) PREDICTED: transformin ( 581) 1996 250.7 1.3e-65
XP_011542939 (OMIM: 605301) PREDICTED: transformin ( 366) 1956 245.8 2.5e-64
XP_011542940 (OMIM: 605301) PREDICTED: transformin ( 338) 1954 245.6 2.7e-64
XP_016869263 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60
NP_001139688 (OMIM: 605301) transforming acidic co ( 610) 1858 234.3 1.2e-60
XP_016869261 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60
XP_016869262 (OMIM: 605301) PREDICTED: transformin ( 610) 1858 234.3 1.2e-60
XP_011542938 (OMIM: 605301) PREDICTED: transformin ( 367) 1568 199.7 1.8e-50
NP_001116296 (OMIM: 605301) transforming acidic co ( 395) 1568 199.8 1.9e-50
XP_006717615 (OMIM: 605302) PREDICTED: transformin (2903) 1003 133.2 1.5e-29
XP_006717617 (OMIM: 605302) PREDICTED: transformin (2887)  990 131.7 4.4e-29
XP_005269449 (OMIM: 605302) PREDICTED: transformin (2969)  990 131.7 4.5e-29
XP_011537435 (OMIM: 605302) PREDICTED: transformin ( 575)  971 129.0 5.8e-29
XP_011537436 (OMIM: 605302) PREDICTED: transformin ( 575)  971 129.0 5.8e-29
NP_001278808 (OMIM: 605302) transforming acidic co ( 575)  971 129.0 5.8e-29
XP_016870988 (OMIM: 605302) PREDICTED: transformin ( 634)  971 129.0 6.3e-29
XP_016870987 (OMIM: 605302) PREDICTED: transformin ( 679)  971 129.0 6.6e-29
XP_016870986 (OMIM: 605302) PREDICTED: transformin ( 679)  971 129.0 6.6e-29
XP_016870985 (OMIM: 605302) PREDICTED: transformin ( 683)  971 129.0 6.7e-29
XP_005269453 (OMIM: 605302) PREDICTED: transformin (2922)  982 130.8 8.6e-29
XP_016870984 (OMIM: 605302) PREDICTED: transformin ( 949)  971 129.1 8.6e-29
XP_016870983 (OMIM: 605302) PREDICTED: transformin ( 966)  971 129.1 8.8e-29
XP_016870982 (OMIM: 605302) PREDICTED: transformin ( 992)  971 129.1   9e-29
NP_996742 (OMIM: 605302) transforming acidic coile ( 996)  971 129.1   9e-29
NP_001278807 (OMIM: 605302) transforming acidic co (1008)  971 129.1 9.1e-29
NP_008928 (OMIM: 605302) transforming acidic coile (1026)  971 129.1 9.2e-29
XP_011537434 (OMIM: 605302) PREDICTED: transformin (1038)  971 129.1 9.3e-29
XP_016870981 (OMIM: 605302) PREDICTED: transformin (1043)  971 129.1 9.3e-29
XP_011537433 (OMIM: 605302) PREDICTED: transformin (1057)  971 129.1 9.4e-29
XP_016870980 (OMIM: 605302) PREDICTED: transformin (1074)  971 129.2 9.5e-29
NP_996743 (OMIM: 605302) transforming acidic coile (1094)  971 129.2 9.7e-29


>>XP_011542935 (OMIM: 605301) PREDICTED: transforming ac  (788 aa)
 initn: 5129 init1: 5129 opt: 5129  Z-score: 3307.9  bits: 622.9 E(85289): 1.6e-177
Smith-Waterman score: 5129; 100.0% identity (100.0% similar) in 788 aa overlap (1-788:1-788)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL
              730       740       750       760       770       780

               
pF1KB9 IAKLGKTD
       ::::::::
XP_011 IAKLGKTD
               

>>XP_011542934 (OMIM: 605301) PREDICTED: transforming ac  (817 aa)
 initn: 3575 init1: 3575 opt: 3596  Z-score: 2323.7  bits: 440.8 E(85289): 1.1e-122
Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE
              490       500       510       520       530       540

                                 540       550       560       570 
pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
                                 ::::::::::::::::::::::::::::::::::
XP_011 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
              550       560       570       580       590       600

             580       590       600       610       620       630 
pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
              610       620       630       640       650       660

             640       650       660       670       680       690 
pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
              670       680       690       700       710       720

             700       710       720       730       740       750 
pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
              730       740       750       760       770       780

             760       770       780        
pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       :::::::::::::::::::::::::::::::::::::
XP_011 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
              790       800       810       

>>XP_005273682 (OMIM: 605301) PREDICTED: transforming ac  (817 aa)
 initn: 3575 init1: 3575 opt: 3596  Z-score: 2323.7  bits: 440.8 E(85289): 1.1e-122
Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_005 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE
              490       500       510       520       530       540

                                 540       550       560       570 
pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
                                 ::::::::::::::::::::::::::::::::::
XP_005 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
              550       560       570       580       590       600

             580       590       600       610       620       630 
pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
              610       620       630       640       650       660

             640       650       660       670       680       690 
pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
              670       680       690       700       710       720

             700       710       720       730       740       750 
pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
              730       740       750       760       770       780

             760       770       780        
pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       :::::::::::::::::::::::::::::::::::::
XP_005 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
              790       800       810       

>>XP_011542933 (OMIM: 605301) PREDICTED: transforming ac  (817 aa)
 initn: 3575 init1: 3575 opt: 3596  Z-score: 2323.7  bits: 440.8 E(85289): 1.1e-122
Smith-Waterman score: 5061; 96.5% identity (96.5% similar) in 817 aa overlap (1-788:1-817)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE
              490       500       510       520       530       540

                                 540       550       560       570 
pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
                                 ::::::::::::::::::::::::::::::::::
XP_011 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
              550       560       570       580       590       600

             580       590       600       610       620       630 
pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
              610       620       630       640       650       660

             640       650       660       670       680       690 
pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
              670       680       690       700       710       720

             700       710       720       730       740       750 
pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
              730       740       750       760       770       780

             760       770       780        
pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       :::::::::::::::::::::::::::::::::::::
XP_011 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
              790       800       810       

>>XP_005273685 (OMIM: 605301) PREDICTED: transforming ac  (789 aa)
 initn: 3194 init1: 3194 opt: 3222  Z-score: 2083.9  bits: 396.4 E(85289): 2.5e-109
Smith-Waterman score: 4687; 93.6% identity (94.6% similar) in 791 aa overlap (28-788:2-789)

               10        20        30         40        50         
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEG-DPEEEDSQAETKSLSFSSDSEG
                                  : ...  :.: .:  :     :..   .:::::
XP_005                           MGGSHSQTPRGREPAGERHPRPTET---ASDSEG
                                         10        20           30 

      60        70        80        90       100       110         
pF1KB9 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE
              40        50        60        70        80        90 

     120       130       140       150       160       170         
pF1KB9 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS
             100       110       120       130       140       150 

     180       190       200       210       220       230         
pF1KB9 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR
             160       170       180       190       200       210 

     240       250       260       270       280       290         
pF1KB9 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS
             220       230       240       250       260       270 

     300       310       320       330       340       350         
pF1KB9 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS
             280       290       300       310       320       330 

     360       370       380       390       400       410         
pF1KB9 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP
             340       350       360       370       380       390 

     420       430       440       450       460       470         
pF1KB9 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC
             400       410       420       430       440       450 

     480       490       500       510       520       530         
pF1KB9 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG--
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_005 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEP
             460       470       480       490       500       510 

                                  540       550       560       570
pF1KB9 ---------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSC
                                  :::::::::::::::::::::::::::::::::
XP_005 EEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSC
             520       530       540       550       560       570 

              580       590       600       610       620       630
pF1KB9 GGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK
             580       590       600       610       620       630 

              640       650       660       670       680       690
pF1KB9 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK
             640       650       660       670       680       690 

              700       710       720       730       740       750
pF1KB9 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR
             700       710       720       730       740       750 

              760       770       780        
pF1KB9 KEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       ::::::::::::::::::::::::::::::::::::::
XP_005 KEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
             760       770       780         

>>XP_005273686 (OMIM: 605301) PREDICTED: transforming ac  (781 aa)
 initn: 3198 init1: 3198 opt: 3221  Z-score: 2083.3  bits: 396.3 E(85289): 2.7e-109
Smith-Waterman score: 4686; 94.9% identity (95.3% similar) in 779 aa overlap (39-788:5-781)

       10        20        30        40        50        60        
pF1KB9 LSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAET
                                     :    :.:.:.  :  ::::::::::::::
XP_005                           MFTLPSTLRSNAKTNHQS--SDSEGNFETPEAET
                                         10          20        30  

       70        80        90       100       110       120        
pF1KB9 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID
             40        50        60        70        80        90  

      130       140       150       160       170       180        
pF1KB9 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP
            100       110       120       130       140       150  

      190       200       210       220       230       240        
pF1KB9 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS
            160       170       180       190       200       210  

      250       260       270       280       290       300        
pF1KB9 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE
            220       230       240       250       260       270  

      310       320       330       340       350       360        
pF1KB9 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT
            280       290       300       310       320       330  

      370       380       390       400       410       420        
pF1KB9 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP
            340       350       360       370       380       390  

      430       440       450       460       470       480        
pF1KB9 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS
            400       410       420       430       440       450  

      490       500       510       520       530                  
pF1KB9 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_005 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFEC
            460       470       480       490       500       510  

                         540       550       560       570         
pF1KB9 ------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI
                         ::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI
            520       530       540       550       560       570  

     580       590       600       610       620       630         
pF1KB9 CLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE
            580       590       600       610       620       630  

     640       650       660       670       680       690         
pF1KB9 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA
            640       650       660       670       680       690  

     700       710       720       730       740       750         
pF1KB9 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL
            700       710       720       730       740       750  

     760       770       780        
pF1KB9 ERALQQKNQEIEELTKICDELIAKLGKTD
       :::::::::::::::::::::::::::::
XP_005 ERALQQKNQEIEELTKICDELIAKLGKTD
            760       770       780 

>>XP_011542936 (OMIM: 605301) PREDICTED: transforming ac  (776 aa)
 initn: 3107 init1: 3107 opt: 3196  Z-score: 2067.3  bits: 393.3 E(85289): 2.1e-108
Smith-Waterman score: 5017; 98.5% identity (98.5% similar) in 788 aa overlap (1-788:1-776)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::            ::::
XP_011 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCK
              430       440       450       460                    

              490       500       510       520       530       540
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEK
      470       480       490       500       510       520        

              550       560       570       580       590       600
pF1KB9 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK
      530       540       550       560       570       580        

              610       620       630       640       650       660
pF1KB9 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA
      590       600       610       620       630       640        

              670       680       690       700       710       720
pF1KB9 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA
      650       660       670       680       690       700        

              730       740       750       760       770       780
pF1KB9 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL
      710       720       730       740       750       760        

               
pF1KB9 IAKLGKTD
       ::::::::
XP_011 IAKLGKTD
      770      

>>NP_006274 (OMIM: 605301) transforming acidic coiled-co  (805 aa)
 initn: 4660 init1: 3107 opt: 3166  Z-score: 2047.8  bits: 389.8 E(85289): 2.5e-107
Smith-Waterman score: 4949; 95.0% identity (95.0% similar) in 817 aa overlap (1-788:1-805)

               10        20        30        40        50        60
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCK
       ::::::::::::::::::::::::::::::::::::::::::::            ::::
NP_006 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCK
              430       440       450       460                    

              490       500       510       520       530          
pF1KB9 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKG---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_006 VKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPE
      470       480       490       500       510       520        

                                 540       550       560       570 
pF1KB9 --------------------------IEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
                                 ::::::::::::::::::::::::::::::::::
NP_006 EDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCG
      530       540       550       560       570       580        

             580       590       600       610       620       630 
pF1KB9 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT
      590       600       610       620       630       640        

             640       650       660       670       680       690 
pF1KB9 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN
      650       660       670       680       690       700        

             700       710       720       730       740       750 
pF1KB9 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
      710       720       730       740       750       760        

             760       770       780        
pF1KB9 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       :::::::::::::::::::::::::::::::::::::
NP_006 EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
      770       780       790       800     

>>XP_016869257 (OMIM: 605301) PREDICTED: transforming ac  (748 aa)
 initn: 2726 init1: 2726 opt: 2822  Z-score: 1827.4  bits: 348.9 E(85289): 4.7e-95
Smith-Waterman score: 4643; 95.5% identity (96.6% similar) in 762 aa overlap (28-788:2-748)

               10        20        30         40        50         
pF1KB9 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEG-DPEEEDSQAETKSLSFSSDSEG
                                  : ...  :.: .:  :     :..   .:::::
XP_016                           MGGSHSQTPRGREPAGERHPRPTET---ASDSEG
                                         10        20           30 

      60        70        80        90       100       110         
pF1KB9 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSE
              40        50        60        70        80        90 

     120       130       140       150       160       170         
pF1KB9 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVS
             100       110       120       130       140       150 

     180       190       200       210       220       230         
pF1KB9 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLR
             160       170       180       190       200       210 

     240       250       260       270       280       290         
pF1KB9 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLS
             220       230       240       250       260       270 

     300       310       320       330       340       350         
pF1KB9 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGIS
             280       290       300       310       320       330 

     360       370       380       390       400       410         
pF1KB9 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDP
             340       350       360       370       380       390 

     420       430       440       450       460       470         
pF1KB9 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGC
       :::::::::::::::::::::::::::::::::::::::::::::            :::
XP_016 DNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGC
             400       410       420       430                     

     480       490       500       510       520       530         
pF1KB9 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIE
     440       450       460       470       480       490         

     540       550       560       570       580       590         
pF1KB9 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIIT
     500       510       520       530       540       550         

     600       610       620       630       640       650         
pF1KB9 KEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQ
     560       570       580       590       600       610         

     660       670       680       690       700       710         
pF1KB9 ALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH
     620       630       640       650       660       670         

     720       730       740       750       760       770         
pF1KB9 AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE
     680       690       700       710       720       730         

     780        
pF1KB9 LIAKLGKTD
       :::::::::
XP_016 LIAKLGKTD
     740        

>>XP_016869258 (OMIM: 605301) PREDICTED: transforming ac  (740 aa)
 initn: 2730 init1: 2730 opt: 2821  Z-score: 1826.9  bits: 348.8 E(85289): 5.1e-95
Smith-Waterman score: 4642; 96.9% identity (97.3% similar) in 750 aa overlap (39-788:5-740)

       10        20        30        40        50        60        
pF1KB9 LSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAET
                                     :    :.:.:.  :  ::::::::::::::
XP_016                           MFTLPSTLRSNAKTNHQS--SDSEGNFETPEAET
                                         10          20        30  

       70        80        90       100       110       120        
pF1KB9 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAID
             40        50        60        70        80        90  

      130       140       150       160       170       180        
pF1KB9 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP
            100       110       120       130       140       150  

      190       200       210       220       230       240        
pF1KB9 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFS
            160       170       180       190       200       210  

      250       260       270       280       290       300        
pF1KB9 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVE
            220       230       240       250       260       270  

      310       320       330       340       350       360        
pF1KB9 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPT
            280       290       300       310       320       330  

      370       380       390       400       410       420        
pF1KB9 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDP
            340       350       360       370       380       390  

      430       440       450       460       470       480        
pF1KB9 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQS
       ::::::::::::::::::::::::::::::::::::            ::::::::::::
XP_016 FKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLIT------------SGCKVKKHETQS
            400       410       420                   430       440

      490       500       510       520       530       540        
pF1KB9 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEKETCQKMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGIEKETCQKMEE
              450       460       470       480       490       500

      550       560       570       580       590       600        
pF1KB9 DGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWK
              510       520       530       540       550       560

      610       620       630       640       650       660        
pF1KB9 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVE
              570       580       590       600       610       620

      670       680       690       700       710       720        
pF1KB9 RSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN
              630       640       650       660       670       680

      730       740       750       760       770       780        
pF1KB9 EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
              690       700       710       720       730       740




788 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:25:10 2016 done: Fri Nov  4 17:25:12 2016
 Total Scan time: 11.320 Total Display time:  0.230

Function used was FASTA [36.3.4 Apr, 2011]
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