Result of FASTA (ccds) for pF1KB8911
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8911, 250 aa
  1>>>pF1KB8911 250 - 250 aa - 250 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3240+/-0.000824; mu= 8.3995+/- 0.050
 mean_var=197.1792+/-41.948, 0's: 0 Z-trim(114.0): 142  B-trim: 863 in 1/53
 Lambda= 0.091336
 statistics sampled from 14426 (14584) to 14426 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.448), width:  16
 Scan time:  2.600

The best scores are:                                      opt bits E(32554)
CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17         ( 250) 1718 237.9   5e-63
CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12          ( 260)  714 105.6 3.5e-23
CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7           ( 272)  592 89.5 2.5e-18
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2           ( 352)  475 74.2 1.3e-13
CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2          ( 340)  432 68.6 6.4e-12
CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12         ( 342)  427 67.9   1e-11
CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7          ( 410)  416 66.5 3.1e-11


>>CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17              (250 aa)
 initn: 1718 init1: 1718 opt: 1718  Z-score: 1244.9  bits: 237.9 E(32554): 5e-63
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250)

               10        20        30        40        50        60
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM
              190       200       210       220       230       240

              250
pF1KB8 KKMNKEQGKE
       ::::::::::
CCDS11 KKMNKEQGKE
              250

>>CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12               (260 aa)
 initn: 769 init1: 485 opt: 714  Z-score: 529.7  bits: 105.6 E(32554): 3.5e-23
Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-247:1-254)

               10        20         30         40         50       
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP
       :: .: .:.:::::.:::..::   ..:: .: . :..:  : .    .:::::: ::  
CCDS88 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
               10        20        30        40        50        60

        60        70        80        90       100           110   
pF1KB8 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ
       ::..::::.  ..:     :::::  ::    :..::.::::::   . . :    :  .
CCDS88 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH
               70            80         90       100       110     

           120            130       140       150       160        
pF1KB8 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE
        :.: .   :     .:::   .. :.: .  : :.    . :     .     ::. ::
CCDS88 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE
         120       130         140        150       160       170  

      170          180       190       200       210       220     
pF1KB8 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS
       .    : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::.
CCDS88 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT
            180       190       200       210       220       230  

         230       240       250   
pF1KB8 ERQVKIWFQNRRMKMKKMNKEQGKE   
       :::::::::::::::::::::.      
CCDS88 ERQVKIWFQNRRMKMKKMNKEKTDKEQS
            240       250       260

>>CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7                (272 aa)
 initn: 704 init1: 485 opt: 592  Z-score: 442.6  bits: 89.5 E(32554): 2.5e-18
Smith-Waterman score: 761; 49.5% identity (69.5% similar) in 275 aa overlap (1-250:1-271)

               10        20        30          40             50   
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSR--QPGH-----AEHLEFPSCSFQ
       :. .:.:..:::::..   . ::   ..  :.:: .   :: .     ::: .:  ::::
CCDS54 MATTGALGNYYVDSFLL--GADAAD-ELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQ
               10          20         30        40        50       

            60        70              80        90           100   
pF1KB8 PKAPVFGASWAPLSPHASGSLPS-VYH-----PYIQPQGVPPA----ESRYLRTWLEPAP
        :: :::::: :.   .....:. :::     ::..::. : :    ..::.:.::::.:
CCDS54 SKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQA-PVAAAAPDGRYMRSWLEPTP
        60        70        80        90        100       110      

              110       120       130       140        150         
pF1KB8 RG---EAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSA-GREAVLSNQRPGYG---
        .    . :..   ..: ::: .  :.     :   ::   : :   :  ...:. :   
CCDS54 GALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFS
        120       130       140       150       160       170      

         160       170       180       190       200       210     
pF1KB8 -DNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRR
        .:   :.. ::   : .::.::::::::.:::::::::.::::::::::::::::::::
CCDS54 ENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRR
        180       190       200       210       220       230      

         220       230       240       250 
pF1KB8 HEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE 
       .::::::::.:::::::::::::::::.::...:. 
CCDS54 YEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
        240       250       260       270  

>>CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2                (352 aa)
 initn: 674 init1: 467 opt: 475  Z-score: 358.0  bits: 74.2 E(32554): 1.3e-13
Smith-Waterman score: 536; 39.9% identity (57.6% similar) in 278 aa overlap (54-247:70-347)

            30        40        50        60          70        80 
pF1KB8 PPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWA--PLSPHASGSLPSVYHPY
                                     :.. ::.:::.  : .: :.... ..::::
CCDS22 PPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPY
      40        50        60        70        80        90         

              90          100                  110       120       
pF1KB8 IQPQGVPPAES---RYLRTWLEPAPR-----------GEAAPGQGQAAVKAEPLLG----
       . :  .  . :   ::.:.:.:: :            : ..::.: .   . :  :    
CCDS22 VPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYG
     100       110       120       130       140       150         

                                            130         140        
pF1KB8 -------APGELL--------------------------KQGT--PEYSLETSAGREAVL
              ::.                             .::.  ::.: ..   ..:. 
CCDS22 IKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAA
     160       170       180       190       200       210         

      150                          160            170              
pF1KB8 SN--QRPGYG-----------------DNKI--CEGSEDKER---PDQ-----TNPSANW
       ..    :: :                 :. :  :  .:....   :.:     .::.:::
CCDS22 ATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANW
     220       230       240       250       260       270         

     180       190       200       210       220       230         
pF1KB8 LHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMK
       .::::.::::::::::::::::::::::::::::::.::::.:::.::::::::::::::
CCDS22 IHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMK
     280       290       300       310       320       330         

     240       250  
pF1KB8 MKKMNKEQGKE  
       ::::.::.     
CCDS22 MKKMSKEKCPKGD
     340       350  

>>CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2               (340 aa)
 initn: 478 init1: 401 opt: 432  Z-score: 327.5  bits: 68.6 E(32554): 6.4e-12
Smith-Waterman score: 436; 39.4% identity (64.2% similar) in 218 aa overlap (35-246:125-327)

           10        20        30        40        50         60   
pF1KB8 GTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQ-PKAPVFGASW
                                     :.. :.. ..:   ::  . :..:: :  .
CCDS22 TQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSY-QRLVPESCPVENPEVPVPG--Y
          100       110       120       130        140       150   

             70        80        90       100       110       120  
pF1KB8 APLSP-HASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLL
         ::  .:.:.     .   .:.:   .        :.  ::: : :  . : .. :  .
CCDS22 FRLSQTYATGKTQEYNN---SPEGSSTV-------MLQLNPRGAAKPQLSAAQLQMEKKM
             160          170              180       190       200 

            130       140       150       160           170        
pF1KB8 GAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKIC----EGSEDKERPDQTNPSAN
       . :  .  :   . :   :   .. : ..:   .. ..     . .:.::.  . .:..:
CCDS22 NEP--VSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSN
               210       220       230       240       250         

      180       190       200       210       220       230        
pF1KB8 WLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRM
       :: :.:.:::::::::.:::::::::::::::::.:: :... .::..::::::::::::
CCDS22 WLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRM
     260       270       280       290       300       310         

      240       250         
pF1KB8 KMKKMNKEQGKE         
       :.:::..:             
CCDS22 KLKKMSRENRIRELTANLTFS
     320       330       340

>>CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12              (342 aa)
 initn: 429 init1: 404 opt: 427  Z-score: 323.9  bits: 67.9 E(32554): 1e-11
Smith-Waterman score: 451; 41.7% identity (65.4% similar) in 211 aa overlap (43-246:140-329)

             20        30        40        50        60        70  
pF1KB8 DSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASG
                                     :: : :  :.   .: ..:     .:: ::
CCDS88 VCCMYSAEKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSA--LDKTPHCSG
     110       120       130       140        150         160      

             80        90             100        110       120     
pF1KB8 SLPSVYHPYIQPQGVPPA----ESRYL--RTWLEPAPRGEA-APGQGQAAVKAEPLLGAP
       .  .   :. :  .. :     ::  :  .. .  .:.... .:. ..  .:.:  :..:
CCDS88 A-NDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNE--IKTEQSLAGP
         170       180       190       200       210         220   

         130       140       150       160       170       180     
pF1KB8 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS
            .:.:  : .    ..:  ... :  .::      : ::.    : ..::: :.:.
CCDS88 -----KGSPSESEK----ERAKAADSSPDTSDN------EAKEEIKAENTTGNWLTAKSG
                230           240             250       260        

         190       200       210       220       230       240     
pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK
       :::::::::.:::::::::::::::::.:: :... .::..:::::::::::::.::::.
CCDS88 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR
      270       280       290       300       310       320        

         250         
pF1KB8 EQGKE         
       :             
CCDS88 ENRIRELTSNFNFT
      330       340  

>>CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7               (410 aa)
 initn: 447 init1: 390 opt: 416  Z-score: 315.2  bits: 66.5 E(32554): 3.1e-11
Smith-Waterman score: 416; 47.8% identity (68.6% similar) in 159 aa overlap (100-246:244-397)

      70        80        90       100            110       120    
pF1KB8 ASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP-----GQGQAAVKAEPLLGA
                                     .:  ::   :     :...:: : . : . 
CCDS54 FRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSP
           220       230       240       250       260       270   

                 130       140       150       160       170       
pF1KB8 PGELL-------KQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSA
       :   :       .::  :    .::..:  ::   :. ....     .:.   .. . .:
CCDS54 PPPTLACGSGGGSQGDEEAHASSSAAEE--LS---PAPSESSKASPEKDSLGNSKGENAA
           280       290       300            310       320        

       180       190       200       210       220       230       
pF1KB8 NWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRR
       ::: :.:.:::::::::.:::::::::::::::::.:: :..: ..:..:::::::::::
CCDS54 NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRR
      330       340       350       360       370       380        

       240       250         
pF1KB8 MKMKKMNKEQGKE         
       ::.::::.:             
CCDS54 MKLKKMNRENRIRELTANFNFS
      390       400       410




250 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:27:54 2016 done: Fri Nov  4 16:27:55 2016
 Total Scan time:  2.600 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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