Result of FASTA (omim) for pF1KB8808
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8808, 355 aa
  1>>>pF1KB8808 355 - 355 aa - 355 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8610+/-0.000515; mu= 19.4109+/- 0.032
 mean_var=107.8083+/-24.742, 0's: 0 Z-trim(109.2): 689  B-trim: 1767 in 2/47
 Lambda= 0.123523
 statistics sampled from 16541 (17327) to 16541 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.203), width:  16
 Scan time:  6.730

The best scores are:                                      opt bits E(85289)
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 2339 428.4 1.2e-119
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 1095 206.7 6.6e-53
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 1095 206.7 6.6e-53
NP_000570 (OMIM: 601373,609532,610379,612522) C-C  ( 352)  999 189.6 9.3e-48
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352)  999 189.6 9.3e-48
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360)  995 188.9 1.5e-47
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360)  995 188.9 1.5e-47
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355)  975 185.3 1.8e-46
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374)  957 182.1 1.7e-45
NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387)  927 176.8 7.1e-44
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355)  925 176.4 8.7e-44
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355)  925 176.4 8.7e-44
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355)  925 176.4 8.7e-44
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355)  925 176.4 8.7e-44
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373)  925 176.4 8.9e-44
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376)  925 176.4   9e-44
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410)  925 176.5 9.5e-44
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410)  925 176.5 9.5e-44
NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355)  918 175.1 2.1e-43
NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355)  918 175.1 2.1e-43
NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355)  918 175.1 2.1e-43
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384)  781 150.8 4.8e-36
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360)  738 143.1 9.4e-34
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360)  738 143.1 9.4e-34
NP_001548 (OMIM: 146928) C-X-C chemokine receptor  ( 360)  738 143.1 9.4e-34
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360)  738 143.1 9.4e-34
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360)  738 143.1 9.4e-34
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360)  738 143.1 9.4e-34
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374)  721 140.0 7.9e-33
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374)  721 140.0 7.9e-33
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350)  715 138.9 1.6e-32
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352)  699 136.1 1.1e-31
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356)  699 136.1 1.2e-31
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357)  696 135.6 1.7e-31
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357)  696 135.6 1.7e-31
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369)  696 135.6 1.7e-31
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369)  696 135.6 1.7e-31
NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372)  688 134.2 4.6e-31
NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372)  688 134.2 4.6e-31
NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372)  688 134.2 4.6e-31
NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378)  688 134.2 4.7e-31
NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315)  658 128.7 1.7e-29
NP_001707 (OMIM: 601613) C-X-C chemokine receptor  ( 372)  652 127.7 3.9e-29
NP_116743 (OMIM: 601613) C-X-C chemokine receptor  ( 327)  642 125.9 1.3e-28
XP_011532511 (OMIM: 608379) PREDICTED: C-C chemoki ( 344)  636 124.9 2.7e-28
XP_011532510 (OMIM: 608379) PREDICTED: C-C chemoki ( 344)  636 124.9 2.7e-28
XP_016862925 (OMIM: 608379) PREDICTED: C-C chemoki ( 344)  636 124.9 2.7e-28
NP_003956 (OMIM: 608379) C-C chemokine receptor-li ( 344)  636 124.9 2.7e-28
NP_001124382 (OMIM: 608379) C-C chemokine receptor ( 356)  636 124.9 2.8e-28
NP_057641 (OMIM: 606065) atypical chemokine recept ( 350)  628 123.4 7.4e-28


>>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8  (355 aa)
 initn: 2339 init1: 2339 opt: 2339  Z-score: 2268.9  bits: 428.4 E(85289): 1.2e-119
Smith-Waterman score: 2339; 99.7% identity (100.0% similar) in 355 aa overlap (1-355:1-355)

               10        20        30        40        50        60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_005 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
              250       260       270       280       290       300

              310       320       330       340       350     
pF1KB8 AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
              310       320       330       340       350     

>>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4  (360 aa)
 initn: 1087 init1: 1060 opt: 1095  Z-score: 1070.8  bits: 206.7 E(85289): 6.6e-53
Smith-Waterman score: 1095; 45.5% identity (75.8% similar) in 347 aa overlap (2-345:8-351)

                     10        20        30        40        50    
pF1KB8       MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNS
              : ::: :.   ..::  . . .::  : :.. :.:.:  .: :.:::.:::::
NP_005 MNPTDIADTTLDESI--YSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNS
               10          20        30        40        50        

           60        70        80        90       100       110    
pF1KB8 LVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYY
       .:.:::   :.:::.:::::::::.::::::::.::  ::  ::::::  .::..: .: 
NP_005 VVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYL
       60        70        80        90       100       110        

          120       130       140       150       160       170    
pF1KB8 IGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQV
       .::::..::. :::.:::::.::::..:..::. .:.   ::.: .:..:..: ..:   
NP_005 VGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTC
      120       130       140       150       160       170        

          180       190       200       210       220       230    
pF1KB8 ASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT
        .: .   : . :. ..  ::.......:::::.::. :..:::  :.. :..:.:..:.
NP_005 YTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKN
      180       190       200       210       220       230        

          240       250       260       270       280       290    
pF1KB8 KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCC
       ::..... ::.  : ::.:.:.:::: .:  ...:. :.. . : :: ..:: ..:.:::
NP_005 KAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCC
      240       250       260       270       280       290        

          300       310       320          330       340       350 
pF1KB8 VNPVIYAFVGEKFKKHLSEIFQKSCSQIF---NYLGRQMPRESCEKSSSCQQHSSRSSSV
       .::.:: :.::::.:.. ..: :.:  .:   .: :  .   .   :::  : .      
NP_005 LNPIIYFFLGEKFRKYILQLF-KTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLH
      300       310        320       330       340       350       

           
pF1KB8 DYIL
           
NP_005 DAL 
       360 

>>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r  (360 aa)
 initn: 1087 init1: 1060 opt: 1095  Z-score: 1070.8  bits: 206.7 E(85289): 6.6e-53
Smith-Waterman score: 1095; 45.5% identity (75.8% similar) in 347 aa overlap (2-345:8-351)

                     10        20        30        40        50    
pF1KB8       MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNS
              : ::: :.   ..::  . . .::  : :.. :.:.:  .: :.:::.:::::
XP_016 MNPTDIADTTLDESI--YSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNS
               10          20        30        40        50        

           60        70        80        90       100       110    
pF1KB8 LVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYY
       .:.:::   :.:::.:::::::::.::::::::.::  ::  ::::::  .::..: .: 
XP_016 VVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYL
       60        70        80        90       100       110        

          120       130       140       150       160       170    
pF1KB8 IGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQV
       .::::..::. :::.:::::.::::..:..::. .:.   ::.: .:..:..: ..:   
XP_016 VGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTC
      120       130       140       150       160       170        

          180       190       200       210       220       230    
pF1KB8 ASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT
        .: .   : . :. ..  ::.......:::::.::. :..:::  :.. :..:.:..:.
XP_016 YTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKN
      180       190       200       210       220       230        

          240       250       260       270       280       290    
pF1KB8 KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCC
       ::..... ::.  : ::.:.:.:::: .:  ...:. :.. . : :: ..:: ..:.:::
XP_016 KAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCC
      240       250       260       270       280       290        

          300       310       320          330       340       350 
pF1KB8 VNPVIYAFVGEKFKKHLSEIFQKSCSQIF---NYLGRQMPRESCEKSSSCQQHSSRSSSV
       .::.:: :.::::.:.. ..: :.:  .:   .: :  .   .   :::  : .      
XP_016 LNPIIYFFLGEKFRKYILQLF-KTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLH
      300       310        320       330       340       350       

           
pF1KB8 DYIL
           
XP_016 DAL 
       360 

>>NP_000570 (OMIM: 601373,609532,610379,612522) C-C chem  (352 aa)
 initn: 1015 init1: 557 opt: 999  Z-score: 978.4  bits: 189.6 E(85289): 9.3e-48
Smith-Waterman score: 999; 42.0% identity (75.0% similar) in 348 aa overlap (1-346:1-343)

               10        20        30        40        50        60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
       ::: ..  .  . .::     : ::.   ..  .  ::  .: :.:.:...:: ::::.:
NP_000 MDYQVSSPIYDI-NYYT----SEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILIL
               10             20        30        40        50     

               70        80        90       100       110       120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
       . ::.:.:.::.::::::.:::.:... :: ..:   :: ::..::....:.:.:::.:.
NP_000 INCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSG
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
       .::: :...::::::::::.:::.::. .:..  . .:..:..:..: ..: .  .:   
NP_000 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH
         120       130       140       150       160       170     

               190       200       210       220       230         
pF1KB8 LQCYS-FYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT-KAIR
         : : :  .:   :: : ..:. ::::..:. ....::  ::. : ::.:..:  .:.:
NP_000 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR
         180       190       200       210       220       230     

      240       250       260       270       280       290        
pF1KB8 LVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPV
       :.. ..:. .:::.:.:.::.:.... .  :..:: :..:  : .::: ...::::.::.
NP_000 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI
         240       250       260       270       280       290     

      300       310       320       330       340       350     
pF1KB8 IYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
       :::::::::...:  .:::  .. :      . .:. :..::   .:.         
NP_000 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
         300       310       320       330       340       350  

>>NP_001093638 (OMIM: 601373,609532,610379,612522) C-C c  (352 aa)
 initn: 1015 init1: 557 opt: 999  Z-score: 978.4  bits: 189.6 E(85289): 9.3e-48
Smith-Waterman score: 999; 42.0% identity (75.0% similar) in 348 aa overlap (1-346:1-343)

               10        20        30        40        50        60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
       ::: ..  .  . .::     : ::.   ..  .  ::  .: :.:.:...:: ::::.:
NP_001 MDYQVSSPIYDI-NYYT----SEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILIL
               10             20        30        40        50     

               70        80        90       100       110       120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
       . ::.:.:.::.::::::.:::.:... :: ..:   :: ::..::....:.:.:::.:.
NP_001 INCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSG
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
       .::: :...::::::::::.:::.::. .:..  . .:..:..:..: ..: .  .:   
NP_001 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH
         120       130       140       150       160       170     

               190       200       210       220       230         
pF1KB8 LQCYS-FYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT-KAIR
         : : :  .:   :: : ..:. ::::..:. ....::  ::. : ::.:..:  .:.:
NP_001 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR
         180       190       200       210       220       230     

      240       250       260       270       280       290        
pF1KB8 LVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPV
       :.. ..:. .:::.:.:.::.:.... .  :..:: :..:  : .::: ...::::.::.
NP_001 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI
         240       250       260       270       280       290     

      300       310       320       330       340       350     
pF1KB8 IYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
       :::::::::...:  .:::  .. :      . .:. :..::   .:.         
NP_001 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
         300       310       320       330       340       350  

>>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ  (360 aa)
 initn: 964 init1: 570 opt: 995  Z-score: 974.5  bits: 188.9 E(85289): 1.5e-47
Smith-Waterman score: 995; 41.5% identity (75.7% similar) in 342 aa overlap (9-346:20-351)

                          10        20        30        40         
pF1KB8            MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
                          :::  :: :    ..::    ..  :  ::  .: :.:.:.
NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
               10        20            30        40        50      

      50        60        70        80        90       100         
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
       ..:: ::.:.:. ::::. .::.::::::.:::::....:. ..   ..::::..:::. 
NP_001 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
         60        70        80        90       100       110      

     110       120       130       140       150       160         
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
       .:.:.::.....::: :...:::::.::::.:::.::. .:..  . .::.:..:..: .
NP_001 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
        120       130       140       150       160       170      

     170       180       190       200       210       220         
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
       .: .  .::.:  :  .. .    :. : ..  :::::..:. :...::  ::. : ::.
NP_001 IFTKCQKEDSVYVCGPYFPR---GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
        180       190          200       210       220       230   

     230        240       250       260       270       280        
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
       :..:  .:.:... ..:. .:::.:.:.:..:.... .  :..:  ..::  ::.::: .
NP_001 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
           240       250       260       270       280       290   

      290       300       310       320       330          340     
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP---RESCEKSSSCQQHS
       ..::::.::.:::::::::...:: .:.:  .. :    .: :   ::. .  .: .  :
NP_001 GMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFC---KQCPVFYRETVDGVTSTNTPS
           300       310       320          330       340       350

         350     
pF1KB8 SRSSSVDYIL
       .         
NP_001 TGEQEVSAGL
              360

>>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r  (360 aa)
 initn: 964 init1: 570 opt: 995  Z-score: 974.5  bits: 188.9 E(85289): 1.5e-47
Smith-Waterman score: 995; 41.5% identity (75.7% similar) in 342 aa overlap (9-346:20-351)

                          10        20        30        40         
pF1KB8            MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
                          :::  :: :    ..::    ..  :  ::  .: :.:.:.
XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
               10        20            30        40        50      

      50        60        70        80        90       100         
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
       ..:: ::.:.:. ::::. .::.::::::.:::::....:. ..   ..::::..:::. 
XP_011 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
         60        70        80        90       100       110      

     110       120       130       140       150       160         
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
       .:.:.::.....::: :...:::::.::::.:::.::. .:..  . .::.:..:..: .
XP_011 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
        120       130       140       150       160       170      

     170       180       190       200       210       220         
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
       .: .  .::.:  :  .. .    :. : ..  :::::..:. :...::  ::. : ::.
XP_011 IFTKCQKEDSVYVCGPYFPR---GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
        180       190          200       210       220       230   

     230        240       250       260       270       280        
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
       :..:  .:.:... ..:. .:::.:.:.:..:.... .  :..:  ..::  ::.::: .
XP_011 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
           240       250       260       270       280       290   

      290       300       310       320       330          340     
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP---RESCEKSSSCQQHS
       ..::::.::.:::::::::...:: .:.:  .. :    .: :   ::. .  .: .  :
XP_011 GMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFC---KQCPVFYRETVDGVTSTNTPS
           300       310       320          330       340       350

         350     
pF1KB8 SRSSSVDYIL
       .         
XP_011 TGEQEVSAGL
              360

>>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1  (355 aa)
 initn: 942 init1: 429 opt: 975  Z-score: 955.3  bits: 185.3 E(85289): 1.8e-46
Smith-Waterman score: 975; 42.6% identity (76.0% similar) in 329 aa overlap (11-337:12-335)

                10        20        30        40        50         
pF1KB8  MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILV
                  :.:.. : :  ..::.    .. :  ::  .: :.::..:.:: ::.::
NP_001 METPNTTEDYDTTTEFDYGD--ATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLV
               10        20          30        40        50        

      60        70        80        90        100       110        
pF1KB8 LVVCKKLRSITDVYLLNLALSDLLFVFSFPFQT-YYLLDQWVFGTVMCKVVSGFYYIGFY
       ::  :.:...:..::::::.:::::.:..::   : : :.:::: .:::..::::: :.:
NP_001 LVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLY
       60        70        80        90       100       110        

      120       130       140       150       160       170        
pF1KB8 SSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASED
       : .::: :...:::::.::::.::..::. .:.   . .:  ::.:..: : : ..  : 
NP_001 SEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEF
      120       130       140       150       160       170        

      180       190        200       210       220       230       
pF1KB8 GVLQCYSFYNQQTLK-WKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAI
           :   . ...:. ::.:  .:.:..::..:. ....::  :.. : :  :..:.::.
NP_001 THHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAV
      180       190       200       210       220       230        

       240       250       260       270       280       290       
pF1KB8 RLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNP
       ::.....:  .:::.:.:...... .... .   :  :..:  :..:::.:..:::::::
NP_001 RLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNP
      240       250       260       270       280       290        

       300       310       320       330       340       350       
pF1KB8 VIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL  
       ::::::::.:.:.: ..:..   ..  .: . .:  : ..                    
NP_001 VIYAFVGERFRKYLRQLFHR---RVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
      300       310          320       330       340       350     

>>NP_001116513 (OMIM: 601267) C-C chemokine receptor typ  (374 aa)
 initn: 898 init1: 570 opt: 957  Z-score: 937.7  bits: 182.1 E(85289): 1.7e-45
Smith-Waterman score: 957; 43.5% identity (78.4% similar) in 301 aa overlap (9-308:20-313)

                          10        20        30        40         
pF1KB8            MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
                          :::  :: :    ..::    ..  :  ::  .: :.:.:.
NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
               10        20            30        40        50      

      50        60        70        80        90       100         
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
       ..:: ::.:.:. ::::. .::.::::::.:::::....:. ..   ..::::..:::. 
NP_001 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
         60        70        80        90       100       110      

     110       120       130       140       150       160         
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
       .:.:.::.....::: :...:::::.::::.:::.::. .:..  . .::.:..:..: .
NP_001 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
        120       130       140       150       160       170      

     170       180       190       200       210       220         
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
       .: .  .::.:  :  .. .    :. : ..  :::::..:. :...::  ::. : ::.
NP_001 IFTKCQKEDSVYVCGPYFPRG---WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
        180       190          200       210       220       230   

     230        240       250       260       270       280        
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
       :..:  .:.:... ..:. .:::.:.:.:..:.... .  :..:  ..::  ::.::: .
NP_001 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
           240       250       260       270       280       290   

      290       300       310       320       330       340        
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRS
       ..::::.::.:::::::::.                                        
NP_001 GMTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDG
           300       310       320       330       340       350   

>>NP_001164645 (OMIM: 601470,607339,609423,613784) CX3C   (387 aa)
 initn: 861 init1: 466 opt: 927  Z-score: 908.6  bits: 176.8 E(85289): 7.1e-44
Smith-Waterman score: 927; 39.8% identity (75.6% similar) in 349 aa overlap (3-350:31-372)

                                           10        20         30 
pF1KB8                             MDYTLDLSVTTVTDYYYPDIFSSPCD-GELIQ
                                     .:.:    .::. .  : ..  :  :... 
NP_001 MREPLEAFKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIV-
               10        20        30        40        50          

              40        50        60        70        80        90 
pF1KB8 TNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQ
       . : ..:..:: ..:...:.:: ::...:.  :: .:.::.::::::::::::: ..:: 
NP_001 VFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFW
      60        70        80        90       100       110         

             100       110       120       130       140       150 
pF1KB8 TYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGT
       :.::...  . ..::: ...:..:::..:.::::..:.:::::.: :. ... ::.. :.
NP_001 THYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGV
     120       130       140       150       160       170         

             160       170       180       190       200       210 
pF1KB8 TLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPF
       :. :.:: .::... : ..: .  .:.  :  :    :.   : .. : . :.::.:.:.
NP_001 TISLGVWAAAILVAAPQFMFTK-QKENECLGDYPEVLQEI--WPVLRNVETNFLGFLLPL
     180       190       200        210         220       230      

             220       230       240       250       260       270 
pF1KB8 TIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDG
        :. .::..:.. :  :.::.:.:::.:.:.:::. .:::.:.::..:: .:. . .. .
NP_001 LIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPS
        240       250       260       270       280       290      

             280       290       300       310       320       330 
pF1KB8 CSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP
       :.. ..:  :  ::: ..:.:::.::.::::.::::...: ... : :  ..   ::.. 
NP_001 CDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGK-CLAVL--CGRSVH
        300       310       320       330       340          350   

             340       350               
pF1KB8 RESCEKSSSCQQHSSRSSSVDYIL          
        .   . :. ..:.:  ::               
NP_001 VDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL
           360       370       380       




355 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 15:45:37 2016 done: Fri Nov  4 15:45:38 2016
 Total Scan time:  6.730 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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