Result of FASTA (omim) for pF1KB8689
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8689, 450 aa
  1>>>pF1KB8689 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0986+/-0.000322; mu= 19.4974+/- 0.020
 mean_var=71.0887+/-14.381, 0's: 0 Z-trim(116.1): 21  B-trim: 0 in 0/54
 Lambda= 0.152116
 statistics sampled from 27002 (27023) to 27002 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.317), width:  16
 Scan time:  9.660

The best scores are:                                      opt bits E(85289)
NP_064596 (OMIM: 607362) repulsive guidance molecu ( 450) 3089 686.9 2.9e-197
NP_001159755 (OMIM: 607362) repulsive guidance mol ( 458) 3055 679.4 5.1e-195
NP_001159759 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159761 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159760 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159758 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
XP_011541648 (OMIM: 612687) PREDICTED: RGM domain  ( 396) 1307 295.8 1.4e-79
XP_005272023 (OMIM: 612687) PREDICTED: RGM domain  ( 477) 1307 295.9 1.6e-79
XP_011541647 (OMIM: 612687) PREDICTED: RGM domain  ( 478) 1307 295.9 1.6e-79
XP_016864880 (OMIM: 612687) PREDICTED: RGM domain  ( 478) 1307 295.9 1.6e-79
XP_016864879 (OMIM: 612687) PREDICTED: RGM domain  ( 478) 1307 295.9 1.6e-79
NP_001012779 (OMIM: 612687) RGM domain family memb ( 478) 1307 295.9 1.6e-79
NP_998818 (OMIM: 602390,608374) hemojuvelin isofor ( 426) 1002 228.9 2.1e-59
XP_005272989 (OMIM: 602390,608374) PREDICTED: hemo ( 426) 1002 228.9 2.1e-59
NP_660320 (OMIM: 602390,608374) hemojuvelin isofor ( 313)  779 179.8 8.7e-45
XP_011541649 (OMIM: 612687) PREDICTED: RGM domain  ( 273)  632 147.5   4e-35
NP_973733 (OMIM: 602390,608374) hemojuvelin isofor ( 200)  366 89.1 1.2e-17
NP_998817 (OMIM: 602390,608374) hemojuvelin isofor ( 200)  366 89.1 1.2e-17
NP_001303696 (OMIM: 602390,608374) hemojuvelin iso ( 200)  366 89.1 1.2e-17


>>NP_064596 (OMIM: 607362) repulsive guidance molecule A  (450 aa)
 initn: 3089 init1: 3089 opt: 3089  Z-score: 3662.6  bits: 686.9 E(85289): 2.9e-197
Smith-Waterman score: 3089; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)

               10        20        30        40        50        60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
              370       380       390       400       410       420

              430       440       450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::
NP_064 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
              430       440       450

>>NP_001159755 (OMIM: 607362) repulsive guidance molecul  (458 aa)
 initn: 3055 init1: 3055 opt: 3055  Z-score: 3622.1  bits: 679.4 E(85289): 5.1e-195
Smith-Waterman score: 3055; 100.0% identity (100.0% similar) in 446 aa overlap (5-450:13-458)

                       10        20        30        40        50  
pF1KB8         MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILK
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGLGPRRAGTSRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILK
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB8 CNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQ
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KB8 HNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLR
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KB8 TFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVY
              190       200       210       220       230       240

            240       250       260       270       280       290  
pF1KB8 QAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTF
              250       260       270       280       290       300

            300       310       320       330       340       350  
pF1KB8 AVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAP
              310       320       330       340       350       360

            360       370       380       390       400       410  
pF1KB8 ETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
              370       380       390       400       410       420

            420       430       440       450
pF1KB8 LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::::::::::
NP_001 LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
              430       440       450        

>>NP_001159759 (OMIM: 607362) repulsive guidance molecul  (434 aa)
 initn: 2972 init1: 2972 opt: 2972  Z-score: 3524.0  bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)

               10        20        30        40        50        60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                               10        20        30        40    

               70        80        90       100       110       120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
          350       360       370       380       390       400    

              430       440       450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
          410       420       430    

>>NP_001159761 (OMIM: 607362) repulsive guidance molecul  (434 aa)
 initn: 2972 init1: 2972 opt: 2972  Z-score: 3524.0  bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)

               10        20        30        40        50        60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                               10        20        30        40    

               70        80        90       100       110       120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
          350       360       370       380       390       400    

              430       440       450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
          410       420       430    

>>NP_001159760 (OMIM: 607362) repulsive guidance molecul  (434 aa)
 initn: 2972 init1: 2972 opt: 2972  Z-score: 3524.0  bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)

               10        20        30        40        50        60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                               10        20        30        40    

               70        80        90       100       110       120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
          350       360       370       380       390       400    

              430       440       450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
          410       420       430    

>>NP_001159758 (OMIM: 607362) repulsive guidance molecul  (434 aa)
 initn: 2972 init1: 2972 opt: 2972  Z-score: 3524.0  bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)

               10        20        30        40        50        60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
                               10        20        30        40    

               70        80        90       100       110       120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
          350       360       370       380       390       400    

              430       440       450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
       ::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
          410       420       430    

>>XP_011541648 (OMIM: 612687) PREDICTED: RGM domain fami  (396 aa)
 initn: 1137 init1: 525 opt: 1307  Z-score: 1549.8  bits: 295.8 E(85289): 1.4e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:7-384)

       10        20        30        40        50        60        
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
                                     :. ::    :.: ::...: : ::  .. .
XP_011                         MPPNCDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
                                       10           20        30   

       70        80        90       100       110       120        
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
       .    ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::      
XP_011 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
            40        50        60        70        80             

      130       140       150                 160       170        
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
                 : .::. :   ..:.:...          :.:  :::::::::::: : :
XP_011 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
                  90       100       110       120       130       

      180       190       200       210       220       230        
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
       :::::.:::::::::::.:::::.::.:::.::::.:.:::::  .::.:::::::  :.
XP_011 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
       140       150       160       170       180       190       

      240       250       260       270       280       290        
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
       ::::::::. .:::.  :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_011 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
       200       210        220       230       240       250      

      300       310       320       330       340       350        
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
       ... . :  .:: : ::. ::::...::      ...:  .  :. . :  .  ...:  
XP_011 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
        260         270       280             290       300        

         360       370       380       390       400       410     
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
         ::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. ::  :.. :.. 
XP_011 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
      310       320       330       340       350       360        

         420       430       440       450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
        . .   :... : ..                   
XP_011 SSGNGTPRGGSDLSVSLGLTCLILIVFL       
      370       380       390             

>>XP_005272023 (OMIM: 612687) PREDICTED: RGM domain fami  (477 aa)
 initn: 1137 init1: 525 opt: 1307  Z-score: 1548.7  bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:88-465)

       10        20        30        40        50        60        
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
                                     :. ::    :.: ::...: : ::  .. .
XP_005 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
        60        70        80        90          100       110    

       70        80        90       100       110       120        
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
       .    ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::      
XP_005 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
          120       130       140       150       160              

      130       140       150                 160       170        
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
                 : .::. :   ..:.:...          :.:  :::::::::::: : :
XP_005 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
                170       180       190       200       210        

      180       190       200       210       220       230        
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
       :::::.:::::::::::.:::::.::.:::.::::.:.:::::  .::.:::::::  :.
XP_005 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
      220       230       240       250       260       270        

      240       250       260       270       280       290        
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
       ::::::::. .:::.  :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_005 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
      280       290        300       310       320       330       

      300       310       320       330       340       350        
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
       ... . :  .:: : ::. ::::...::      ...:  .  :. . :  .  ...:  
XP_005 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
       340         350       360             370       380         

         360       370       380       390       400       410     
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
         ::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. ::  :.. :.. 
XP_005 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
     390       400       410       420       430       440         

         420       430       440       450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
        . .   :... : ..                   
XP_005 SSGNGTPRGGSDLSVSLGLTCLILIVFL       
     450       460       470              

>>XP_011541647 (OMIM: 612687) PREDICTED: RGM domain fami  (478 aa)
 initn: 1137 init1: 525 opt: 1307  Z-score: 1548.7  bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:89-466)

       10        20        30        40        50        60        
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
                                     :. ::    :.: ::...: : ::  .. .
XP_011 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
       60        70        80        90          100       110     

       70        80        90       100       110       120        
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
       .    ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::      
XP_011 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
         120       130       140       150       160               

      130       140       150                 160       170        
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
                 : .::. :   ..:.:...          :.:  :::::::::::: : :
XP_011 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
               170       180       190       200       210         

      180       190       200       210       220       230        
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
       :::::.:::::::::::.:::::.::.:::.::::.:.:::::  .::.:::::::  :.
XP_011 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
     220       230       240       250       260       270         

      240       250       260       270       280       290        
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
       ::::::::. .:::.  :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_011 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
     280       290        300       310       320       330        

      300       310       320       330       340       350        
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
       ... . :  .:: : ::. ::::...::      ...:  .  :. . :  .  ...:  
XP_011 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
      340         350       360             370       380       390

         360       370       380       390       400       410     
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
         ::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. ::  :.. :.. 
XP_011 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
              400       410       420       430       440       450

         420       430       440       450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
        . .   :... : ..                   
XP_011 SSGNGTPRGGSDLSVSLGLTCLILIVFL       
              460       470               

>>XP_016864880 (OMIM: 612687) PREDICTED: RGM domain fami  (478 aa)
 initn: 1137 init1: 525 opt: 1307  Z-score: 1548.7  bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:89-466)

       10        20        30        40        50        60        
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
                                     :. ::    :.: ::...: : ::  .. .
XP_016 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
       60        70        80        90          100       110     

       70        80        90       100       110       120        
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
       .    ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::      
XP_016 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
         120       130       140       150       160               

      130       140       150                 160       170        
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
                 : .::. :   ..:.:...          :.:  :::::::::::: : :
XP_016 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
               170       180       190       200       210         

      180       190       200       210       220       230        
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
       :::::.:::::::::::.:::::.::.:::.::::.:.:::::  .::.:::::::  :.
XP_016 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
     220       230       240       250       260       270         

      240       250       260       270       280       290        
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
       ::::::::. .:::.  :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_016 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
     280       290        300       310       320       330        

      300       310       320       330       340       350        
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
       ... . :  .:: : ::. ::::...::      ...:  .  :. . :  .  ...:  
XP_016 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
      340         350       360             370       380       390

         360       370       380       390       400       410     
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
         ::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. ::  :.. :.. 
XP_016 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
              400       410       420       430       440       450

         420       430       440       450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
        . .   :... : ..                   
XP_016 SSGNGTPRGGSDLSVSLGLTCLILIVFL       
              460       470               




450 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:36:50 2016 done: Fri Nov  4 14:36:51 2016
 Total Scan time:  9.660 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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