Result of FASTA (omim) for pF1KB8662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8662, 377 aa
  1>>>pF1KB8662 377 - 377 aa - 377 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.4467+/-0.000623; mu= -8.3363+/- 0.038
 mean_var=301.7505+/-62.813, 0's: 0 Z-trim(113.7): 90  B-trim: 1037 in 2/53
 Lambda= 0.073833
 statistics sampled from 23052 (23139) to 23052 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.271), width:  16
 Scan time:  7.940

The best scores are:                                      opt bits E(85289)
NP_054876 (OMIM: 616070) coiled-coil domain-contai ( 377) 2370 266.6 6.9e-71
XP_011521340 (OMIM: 616070) PREDICTED: coiled-coil ( 350) 2161 244.3 3.3e-64
XP_011521341 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62
XP_011521343 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62
XP_011521342 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62
XP_016878665 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62
XP_011521344 (OMIM: 616070) PREDICTED: coiled-coil ( 310) 1856 211.8 1.8e-54
XP_016878666 (OMIM: 616070) PREDICTED: coiled-coil ( 289) 1807 206.5 6.3e-53
NP_001135774 (OMIM: 616070) coiled-coil domain-con ( 323) 1537 177.8 3.1e-44
XP_016878667 (OMIM: 616070) PREDICTED: coiled-coil ( 222) 1293 151.7 1.6e-36


>>NP_054876 (OMIM: 616070) coiled-coil domain-containing  (377 aa)
 initn: 2370 init1: 2370 opt: 2370  Z-score: 1393.6  bits: 266.6 E(85289): 6.9e-71
Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377)

               10        20        30        40        50        60
pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
              310       320       330       340       350       360

              370       
pF1KB8 RMKITNEQLQADYLAGK
       :::::::::::::::::
NP_054 RMKITNEQLQADYLAGK
              370       

>>XP_011521340 (OMIM: 616070) PREDICTED: coiled-coil dom  (350 aa)
 initn: 2161 init1: 2161 opt: 2161  Z-score: 1273.8  bits: 244.3 E(85289): 3.3e-64
Smith-Waterman score: 2161; 100.0% identity (100.0% similar) in 344 aa overlap (34-377:7-350)

            10        20        30        40        50        60   
pF1KB8 DESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPR
                                     ::::::::::::::::::::::::::::::
XP_011                         MHYRRWSYVNSALKTETEMFEKYYAKLEPRDQRPPR
                                       10        20        30      

            70        80        90       100       110       120   
pF1KB8 LSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAE
         40        50        60        70        80        90      

           130       140       150       160       170       180   
pF1KB8 RDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRD
        100       110       120       130       140       150      

           190       200       210       220       230       240   
pF1KB8 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQEL
        160       170       180       190       200       210      

           250       260       270       280       290       300   
pF1KB8 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE
        220       230       240       250       260       270      

           310       320       330       340       350       360   
pF1KB8 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMK
        280       290       300       310       320       330      

           370       
pF1KB8 ITNEQLQADYLAGK
       ::::::::::::::
XP_011 ITNEQLQADYLAGK
        340       350

>>XP_011521341 (OMIM: 616070) PREDICTED: coiled-coil dom  (332 aa)
 initn: 2093 init1: 2093 opt: 2093  Z-score: 1234.9  bits: 237.0 E(85289): 4.8e-62
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332)

          20        30        40        50        60        70     
pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                     ::::::::::::::::::::::::::::::
XP_011                               MFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                             10        20        30

          80        90       100       110       120       130     
pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
              280       290       300       310       320       330

         
pF1KB8 GK
       ::
XP_011 GK
         

>>XP_011521343 (OMIM: 616070) PREDICTED: coiled-coil dom  (332 aa)
 initn: 2093 init1: 2093 opt: 2093  Z-score: 1234.9  bits: 237.0 E(85289): 4.8e-62
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332)

          20        30        40        50        60        70     
pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                     ::::::::::::::::::::::::::::::
XP_011                               MFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                             10        20        30

          80        90       100       110       120       130     
pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
              280       290       300       310       320       330

         
pF1KB8 GK
       ::
XP_011 GK
         

>>XP_011521342 (OMIM: 616070) PREDICTED: coiled-coil dom  (332 aa)
 initn: 2093 init1: 2093 opt: 2093  Z-score: 1234.9  bits: 237.0 E(85289): 4.8e-62
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332)

          20        30        40        50        60        70     
pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                     ::::::::::::::::::::::::::::::
XP_011                               MFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                             10        20        30

          80        90       100       110       120       130     
pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
              280       290       300       310       320       330

         
pF1KB8 GK
       ::
XP_011 GK
         

>>XP_016878665 (OMIM: 616070) PREDICTED: coiled-coil dom  (332 aa)
 initn: 2093 init1: 2093 opt: 2093  Z-score: 1234.9  bits: 237.0 E(85289): 4.8e-62
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332)

          20        30        40        50        60        70     
pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                     ::::::::::::::::::::::::::::::
XP_016                               MFEKYYAKLEPRDQRPPRLSEIKISAADYA
                                             10        20        30

          80        90       100       110       120       130     
pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
              280       290       300       310       320       330

         
pF1KB8 GK
       ::
XP_016 GK
         

>>XP_011521344 (OMIM: 616070) PREDICTED: coiled-coil dom  (310 aa)
 initn: 1856 init1: 1856 opt: 1856  Z-score: 1098.9  bits: 211.8 E(85289): 1.8e-54
Smith-Waterman score: 1856; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEETVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
                                                                   
XP_011 LYHSGWSAAS                                                  
              310                                                  

>>XP_016878666 (OMIM: 616070) PREDICTED: coiled-coil dom  (289 aa)
 initn: 1807 init1: 1807 opt: 1807  Z-score: 1071.1  bits: 206.5 E(85289): 6.3e-53
Smith-Waterman score: 1807; 100.0% identity (100.0% similar) in 289 aa overlap (89-377:1-289)

       60        70        80        90       100       110        
pF1KB8 QRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHT
                                     ::::::::::::::::::::::::::::::
XP_016                               MDRGVGLTADQKLELVQKEVADMKDDLRHT
                                             10        20        30

      120       130       140       150       160       170        
pF1KB8 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM
               40        50        60        70        80        90

      180       190       200       210       220       230        
pF1KB8 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA
              100       110       120       130       140       150

      240       250       260       270       280       290        
pF1KB8 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED
              160       170       180       190       200       210

      300       310       320       330       340       350        
pF1KB8 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA
              220       230       240       250       260       270

      360       370       
pF1KB8 WNRMKITNEQLQADYLAGK
       :::::::::::::::::::
XP_016 WNRMKITNEQLQADYLAGK
              280         

>>NP_001135774 (OMIM: 616070) coiled-coil domain-contain  (323 aa)
 initn: 1533 init1: 1533 opt: 1537  Z-score: 915.0  bits: 177.8 E(85289): 3.1e-44
Smith-Waterman score: 1896; 85.7% identity (85.7% similar) in 377 aa overlap (1-377:1-323)

               10        20        30        40        50        60
pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
       ::::::::::::::::                                            
NP_001 PPRLSEIKISAADYAQ--------------------------------------------
               70                                                  

              130       140       150       160       170       180
pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------AIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
                   80        90       100       110       120      

              190       200       210       220       230       240
pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
        130       140       150       160       170       180      

              250       260       270       280       290       300
pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
        190       200       210       220       230       240      

              310       320       330       340       350       360
pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN
        250       260       270       280       290       300      

              370       
pF1KB8 RMKITNEQLQADYLAGK
       :::::::::::::::::
NP_001 RMKITNEQLQADYLAGK
        310       320   

>>XP_016878667 (OMIM: 616070) PREDICTED: coiled-coil dom  (222 aa)
 initn: 1293 init1: 1293 opt: 1293  Z-score: 776.8  bits: 151.7 E(85289): 1.6e-36
Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 209 aa overlap (89-297:1-209)

       60        70        80        90       100       110        
pF1KB8 QRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHT
                                     ::::::::::::::::::::::::::::::
XP_016                               MDRGVGLTADQKLELVQKEVADMKDDLRHT
                                             10        20        30

      120       130       140       150       160       170        
pF1KB8 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM
               40        50        60        70        80        90

      180       190       200       210       220       230        
pF1KB8 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA
              100       110       120       130       140       150

      240       250       260       270       280       290        
pF1KB8 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEET
              160       170       180       190       200       210

      300       310       320       330       340       350        
pF1KB8 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA
                                                                   
XP_016 VSLYHSGWSAAS                                                
              220                                                  




377 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:20:05 2016 done: Fri Nov  4 14:20:06 2016
 Total Scan time:  7.940 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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