Result of FASTA (ccds) for pF1KB8657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8657, 454 aa
  1>>>pF1KB8657 454 - 454 aa - 454 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5388+/-0.000999; mu= 16.0773+/- 0.060
 mean_var=70.8835+/-14.414, 0's: 0 Z-trim(104.5): 47  B-trim: 20 in 1/48
 Lambda= 0.152336
 statistics sampled from 7888 (7923) to 7888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.243), width:  16
 Scan time:  1.890

The best scores are:                                      opt bits E(32554)
CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7          ( 454) 2982 664.9 4.7e-191
CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7         ( 436) 2705 604.0 9.6e-173
CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7         ( 443) 2661 594.4 7.9e-170
CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7         ( 425) 2384 533.5 1.6e-151
CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7         ( 384) 2208 494.8 6.5e-140
CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17        ( 446) 1574 355.5 6.5e-98
CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17        ( 364) 1367 309.9 2.7e-84
CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17       ( 344)  388 94.8 1.5e-19
CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX         ( 360)  319 79.6 5.8e-15
CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX         ( 361)  319 79.6 5.8e-15


>>CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7               (454 aa)
 initn: 2982 init1: 2982 opt: 2982  Z-score: 3543.6  bits: 664.9 E(32554): 4.7e-191
Smith-Waterman score: 2982; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
              370       380       390       400       410       420

              430       440       450    
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
       ::::::::::::::::::::::::::::::::::
CCDS53 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
              430       440       450    

>>CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7              (436 aa)
 initn: 2851 init1: 2705 opt: 2705  Z-score: 3214.8  bits: 604.0 E(32554): 9.6e-173
Smith-Waterman score: 2819; 96.0% identity (96.0% similar) in 454 aa overlap (1-454:1-436)

               10        20        30        40        50        60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
       :::::::::::::::::::::::::                  :::::::::::::::::
CCDS34 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
               10        20                          30        40  

               70        80        90       100       110       120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
            350       360       370       380       390       400  

              430       440       450    
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
       ::::::::::::::::::::::::::::::::::
CCDS34 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
            410       420       430      

>>CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7              (443 aa)
 initn: 2895 init1: 2661 opt: 2661  Z-score: 3162.5  bits: 594.4 E(32554): 7.9e-170
Smith-Waterman score: 2877; 97.6% identity (97.6% similar) in 454 aa overlap (1-454:1-443)

               10        20        30        40        50        60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
       ::::::::::::::::::::::::::::::::::::::::::::::           :::
CCDS47 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
              370       380       390       400                    

              430       440       450    
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
       ::::::::::::::::::::::::::::::::::
CCDS47 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
     410       420       430       440   

>>CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7              (425 aa)
 initn: 2764 init1: 2384 opt: 2384  Z-score: 2833.7  bits: 533.5 E(32554): 1.6e-151
Smith-Waterman score: 2714; 93.6% identity (93.6% similar) in 454 aa overlap (1-454:1-425)

               10        20        30        40        50        60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
       :::::::::::::::::::::::::                  :::::::::::::::::
CCDS47 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
               10        20                          30        40  

               70        80        90       100       110       120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
       ::::::::::::::::::::::::::::::::::::::::::::::           :::
CCDS47 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
            350       360       370       380                  390 

              430       440       450    
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
       ::::::::::::::::::::::::::::::::::
CCDS47 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
             400       410       420     

>>CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7              (384 aa)
 initn: 2442 init1: 2208 opt: 2208  Z-score: 2625.3  bits: 494.8 E(32554): 6.5e-140
Smith-Waterman score: 2424; 97.1% identity (97.1% similar) in 383 aa overlap (72-454:13-384)

              50        60        70        80        90       100 
pF1KB8 VWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKV
                                     ::::::::::::::::::::::::::::::
CCDS47                   MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKV
                                 10        20        30        40  

             110       120       130       140       150       160 
pF1KB8 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
             50        60        70        80        90       100  

             170       180       190       200       210       220 
pF1KB8 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
            110       120       130       140       150       160  

             230       240       250       260       270       280 
pF1KB8 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
            170       180       190       200       210       220  

             290       300       310       320       330       340 
pF1KB8 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
            230       240       250       260       270       280  

             350       360       370       380       390       400 
pF1KB8 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
            290       300       310       320       330       340  

             410       420       430       440       450    
pF1KB8 AAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
       :::::           :::::::::::::::::::::::::::::::::::::
CCDS47 AAAGK-----------AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
                       350       360       370       380    

>>CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17             (446 aa)
 initn: 1540 init1: 1499 opt: 1574  Z-score: 1871.3  bits: 355.5 E(32554): 6.5e-98
Smith-Waterman score: 1574; 58.9% identity (84.9% similar) in 411 aa overlap (44-451:28-434)

            20        30        40        50        60        70   
pF1KB8 QLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDT
                                     :::.:.:.:::.::::::..:.:..  .. 
CCDS11    MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEI
                  10        20        30        40        50       

            80        90       100       110       120       130   
pF1KB8 EDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
        :: :::::::::::..::   ::...: ::::::::::::::..::...::::::.:::
CCDS11 PDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCL
        60        70        80        90       100       110       

           140       150       160       170       180       190   
pF1KB8 EESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR
       :::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..:  .:.
CCDS11 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK
       120       130       140       150       160       170       

           200       210       220       230       240       250   
pF1KB8 AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICS
       ..  : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.:: :.: :
CCDS11 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS
       180       190       200       210       220       230       

           260       270       280       290       300       310   
pF1KB8 LAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM
       :.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.::..:
CCDS11 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDM
       240       250       260       270       280       290       

           320       330       340       350       360       370   
pF1KB8 FNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQH
       ..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.:.: :
CCDS11 MHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTH
       300       310       320       330       340       350       

           380       390       400       410       420       430   
pF1KB8 RLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLED
        : ::  ::.:  .. .   : . :.:.:.... . . :. :  .:..: ::. :  . .
CCDS11 SLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRGEVIPE
       360          370       380        390       400       410   

              440       450             
pF1KB8 EASA---LRLDEDSEHPPMILRTD         
       .  :   . ::...: ::.::            
CCDS11 HEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
           420       430       440      

>>CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17             (364 aa)
 initn: 1333 init1: 1292 opt: 1367  Z-score: 1626.8  bits: 309.9 E(32554): 2.7e-84
Smith-Waterman score: 1367; 58.7% identity (84.8% similar) in 356 aa overlap (99-451:1-352)

       70        80        90       100       110       120        
pF1KB8 ECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQR
                                     ..: ::::::::::::::..::...:::::
CCDS82                               MNVYHFKKGTEICNYSYSSNILSIRLNRQR
                                             10        20        30

      130       140       150       160       170       180        
pF1KB8 LIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFD
       :.::::::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..:
CCDS82 LLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD
               40        50        60        70        80        90

      190       200       210       220       230       240        
pF1KB8 TINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
         .:...  : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.:: 
CCDS82 GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRY
              100       110       120       130       140       150

      250       260       270       280       290       300        
pF1KB8 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
       :.: ::.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.
CCDS82 VTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT
              160       170       180       190       200       210

      310       320       330       340       350       360        
pF1KB8 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECA
       ::..:..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.
CCDS82 QVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECV
              220       230       240       250       260       270

      370       380       390       400       410       420        
pF1KB8 LMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGG
       :.: : : ::  ::.:  .. .   : . :.:.:.... . . :. :  .:..: ::. :
CCDS82 LIKTHSLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRG
              280          290       300        310       320      

      430          440       450             
pF1KB8 ACLEDEASA---LRLDEDSEHPPMILRTD         
         . ..  :   . ::...: ::.::            
CCDS82 EVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
        330       340       350       360    

>>CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17            (344 aa)
 initn: 343 init1: 276 opt: 388  Z-score: 464.3  bits: 94.8 E(32554): 1.5e-19
Smith-Waterman score: 443; 31.0% identity (56.8% similar) in 368 aa overlap (11-367:10-328)

               10        20        30        40        50        60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
                 : : ::.:.::::.    :               .: : ..:.. .. . 
CCDS11  MNLLPCNPHGNG-LLYAGFNQDH----GC--------------FACGMENGFRVYNTDP
                10         20                          30        40

               70        80        90            100       110     
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY
       . . :.  :  .   :  :: ::  . .:.:.  : :.    :. .    :   . .  .
CCDS11 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF
                50         60        70        80        90        

         120       130           140       150       160       170 
pF1KB8 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC
       :. . :::: :.:..: :.  .    . :: ....:.    ::  :: :::.:  :..: 
CCDS11 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS
      100       110       120       130           140       150    

             180       190        200       210       220       230
pF1KB8 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF
        ::.::. : :.::. :  . .   . ::::.. :. .:.. .::..::::::::.::.:
CCDS11 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF
          160        170       180       190       200       210   

              240       250       260       270       280       290
pF1KB8 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT
       .   :. . :.::: .     : . :..:. .. .::.  :::::  :  :..       
CCDS11 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS---
           220       230        240       250       260            

              300       310       320       330       340          
pF1KB8 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-
                .::.:.::    ..:..  .:.  ..:  :   ::...:    :  ...  
CCDS11 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGT---EPNAVIAIC
              270           280       290        300          310  

     350       360       370       380       390       400         
pF1KB8 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTY
       :::  : . ..:.  :::                                          
CCDS11 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL                          
            320         330       340                              

>>CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX              (360 aa)
 initn: 260 init1: 138 opt: 319  Z-score: 382.1  bits: 79.6 E(32554): 5.8e-15
Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (78-367:53-343)

        50        60        70        80        90        100      
pF1KB8 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF--
                                     .:: :  :.:.:.:.  ..:.  ..  .  
CCDS35 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW
             30        40        50        60        70        80  

                  110       120       130       140       150      
pF1KB8 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP
          ..: .     . ...... .:.:.. ...... :.. .:.... :        .:  
CCDS35 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD
             90       100       110       120       130       140  

        160       170       180       190            200       210 
pF1KB8 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD
       :: ::: :  . ..  :..::    : .:. :  . .     :   : ::.: .: ....
CCDS35 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN
            150       160        170       180       190       200 

             220       230       240       250       260       270 
pF1KB8 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET
         :: .:.::.:::.::.:.    .:: :.:::.   .  : . :: :. :: :::.  :
CCDS35 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT
             210       220       230       240        250       260

             280       290       300       310       320       330 
pF1KB8 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK
       :::: :. ..     .  .  .  :::     .:. :: .        .:.  .:     
CCDS35 VHIFALKDTR----LNRRSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA
              270           280       290               300        

               340       350       360       370       380         
pF1KB8 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA
        ::...  : ...  ...  .:: .. : . :.  :.:                      
CCDS35 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF     
       310       320       330       340         350       360     

     390       400       410       420       430       440         
pF1KB8 SHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPM

>>CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX              (361 aa)
 initn: 260 init1: 138 opt: 319  Z-score: 382.1  bits: 79.6 E(32554): 5.8e-15
Smith-Waterman score: 333; 26.5% identity (56.6% similar) in 309 aa overlap (78-367:53-344)

        50        60        70        80        90        100      
pF1KB8 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF--
                                     .:: :  :.:.:.:.  ..:.  ..     
CCDS14 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISAVLI
             30        40        50        60        70        80  

                   110       120       130       140       150     
pF1KB8 ----KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETP
           ..: .     . ...... .:.:.. ...... :.. .:.... :        .: 
CCDS14 WDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTR
             90       100       110       120       130       140  

         160       170       180       190            200       210
pF1KB8 PNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAF
        :: ::: :  . ..  :..::    : .:. :  . .     :   : ::.: .: ...
CCDS14 DNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSL
            150       160        170       180       190       200 

              220       230       240       250       260       270
pF1KB8 DASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTE
       .  :: .:.::.:::.::.:.    .:: :.:::.   .  : . :: :. :: :::.  
CCDS14 NQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKG
             210       220       230       240        250       260

              280       290       300       310       320       330
pF1KB8 TVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGH
       ::::: :. ..     .  .  .  :::     .:. :: .        .:.  .:    
CCDS14 TVHIFALKDTR----LNRRSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AES
              270           280       290               300        

                340       350       360       370       380        
pF1KB8 KNICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDS
         ::...  : ...  ...  .:: .. : . :.  :.:                     
CCDS14 ACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF    
       310       320       330       340         350       360     

      390       400       410       420       430       440        
pF1KB8 ASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPP




454 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:14:15 2016 done: Fri Nov  4 14:14:15 2016
 Total Scan time:  1.890 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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