Result of FASTA (omim) for pF1KB8632
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8632, 838 aa
  1>>>pF1KB8632 838 - 838 aa - 838 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1105+/-0.000467; mu= 12.7463+/- 0.029
 mean_var=129.4801+/-26.435, 0's: 0 Z-trim(113.6): 112  B-trim: 469 in 1/50
 Lambda= 0.112713
 statistics sampled from 22831 (22947) to 22831 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.269), width:  16
 Scan time: 11.180

The best scores are:                                      opt bits E(85289)
NP_001171805 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4       0
NP_001004051 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4       0
NP_612446 (OMIM: 300969) G-protein coupled recepto ( 838) 5566 917.4       0
NP_001171804 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4       0
NP_001171803 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4       0
NP_001092881 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
XP_016885471 (OMIM: 300417) PREDICTED: G-protein c (1395) 2043 344.7 1.8e-93
NP_001092880 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
XP_016885470 (OMIM: 300417) PREDICTED: G-protein c (1395) 2043 344.7 1.8e-93
NP_055525 (OMIM: 300417) G-protein coupled recepto (1395) 2043 344.7 1.8e-93
NP_001171656 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
NP_001136001 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_085142 (OMIM: 300921) protein BHLHb9 [Homo sapi ( 547)  824 146.2 3.9e-34
NP_001136000 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_001135997 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_001135999 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_001136002 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_001135996 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_001135998 (OMIM: 300921) protein BHLHb9 [Homo s ( 547)  824 146.2 3.9e-34
NP_057692 (OMIM: 300362) armadillo repeat-containi ( 453)  424 81.1 1.3e-14
NP_808817 (OMIM: 300364) armadillo repeat-containi ( 379)  415 79.5 3.1e-14
XP_005262198 (OMIM: 300364) PREDICTED: armadillo r ( 379)  415 79.5 3.1e-14
NP_808816 (OMIM: 300364) armadillo repeat-containi ( 379)  415 79.5 3.1e-14
NP_057691 (OMIM: 300364) armadillo repeat-containi ( 379)  415 79.5 3.1e-14
XP_016868176 (OMIM: 611864) PREDICTED: armadillo r ( 273)  404 77.7 8.1e-14
XP_011514904 (OMIM: 611864) PREDICTED: armadillo r ( 280)  404 77.7 8.3e-14
NP_001154481 (OMIM: 611864) armadillo repeat-conta ( 308)  404 77.7   9e-14
XP_011514903 (OMIM: 611864) PREDICTED: armadillo r ( 316)  404 77.7 9.1e-14
NP_114111 (OMIM: 611864) armadillo repeat-containi ( 343)  404 77.7 9.8e-14
XP_016868173 (OMIM: 611864) PREDICTED: armadillo r ( 352)  404 77.7   1e-13
XP_005278172 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885477 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_005278171 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_005278168 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885481 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
NP_055597 (OMIM: 300363) armadillo repeat-containi ( 632)  321 64.4 1.8e-09
XP_016885479 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885478 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
NP_808818 (OMIM: 300363) armadillo repeat-containi ( 632)  321 64.4 1.8e-09
XP_016885476 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885486 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885484 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_005278173 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885482 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_005278166 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_005278174 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_011529373 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
NP_001269160 (OMIM: 300363) armadillo repeat-conta ( 632)  321 64.4 1.8e-09
XP_005278167 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09
XP_016885485 (OMIM: 300363) PREDICTED: armadillo r ( 632)  321 64.4 1.8e-09


>>NP_001171805 (OMIM: 300969) G-protein coupled receptor  (838 aa)
 initn: 5566 init1: 5566 opt: 5566  Z-score: 4898.5  bits: 917.4 E(85289):    0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
              790       800       810       820       830        

>>NP_001004051 (OMIM: 300969) G-protein coupled receptor  (838 aa)
 initn: 5566 init1: 5566 opt: 5566  Z-score: 4898.5  bits: 917.4 E(85289):    0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
              790       800       810       820       830        

>>NP_612446 (OMIM: 300969) G-protein coupled receptor-as  (838 aa)
 initn: 5566 init1: 5566 opt: 5566  Z-score: 4898.5  bits: 917.4 E(85289):    0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
              790       800       810       820       830        

>>NP_001171804 (OMIM: 300969) G-protein coupled receptor  (838 aa)
 initn: 5566 init1: 5566 opt: 5566  Z-score: 4898.5  bits: 917.4 E(85289):    0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
              790       800       810       820       830        

>>NP_001171803 (OMIM: 300969) G-protein coupled receptor  (838 aa)
 initn: 5566 init1: 5566 opt: 5566  Z-score: 4898.5  bits: 917.4 E(85289):    0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
              730       740       750       760       770       780

              790       800       810       820       830        
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
              790       800       810       820       830        

>>NP_001092881 (OMIM: 300417) G-protein coupled receptor  (1395 aa)
 initn: 2409 init1: 1468 opt: 2043  Z-score: 1799.2  bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)

       10        20        30        40          50        60      
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
                                     .:  .:  :  ::: .: ... ..   .: 
NP_001 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
      530       540       550       560       570       580        

         70        80        90         100       110       120    
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
       :..   : .:  ..: ::.   : . : :.    ...: . : . ::.. .    :  : 
NP_001 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
      590       600          610       620       630       640     

           130       140        150             160       170      
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
         :.  .. . :: .  .   :. .::  .  :    :     .:.  ::.    ....:
NP_001 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
         650       660       670       680       690        700    

        180       190       200        210       220            230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
       :    .   :. .  :  :.   ::.:. :.   ..  ..::.  .: ::. ::     :
NP_001 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
          710       720       730       740       750       760    

              240        250       260       270       280         
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
       .   :   .:: ..  ::    .. ..: .   .:  ..:  ...:. : :: :...:. 
NP_001 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
          770       780         790       800       810       820  

     290       300       310       320               330           
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
         .   .:  ...   :...::  : ..   ..:          :::.    :.:.   :
NP_001 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
               830         840       850       860       870       

      340       350       360          370               380       
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
       :  : :::. .   .  :. ..  .   . ..   :. .:..:        :. .::.:.
NP_001 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
       880       890       900       910       920       930       

       390       400       410       420           430       440   
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
        ::::.. .:  : :. : :::.: .::::: :: . ::.    ... :.    ..  . 
NP_001 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
       940       950       960       970       980       990       

           450       460       470       480        490       500  
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
       :.::: :::::  ::: :. :: ::...  :   ..: : . : :::.:.::::.:::: 
NP_001 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
       1000      1010      1020      1030      1040      1050      

            510       520           530       540       550        
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
       .  ::: : ::: .:.::.    ::. .::.:. ::::::.:::::::::::::: ::::
NP_001 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
       1060      1070      1080      1090      1100      1110      

      560       570       580       590       600       610        
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
       ::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_001 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
       1120      1130      1140      1150      1160      1170      

      620       630       640       650       660       670        
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
       :::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_001 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
       1180      1190      1200      1210      1220      1230      

      680       690       700       710       720       730        
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
       ::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_001 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
       1240      1250      1260      1270      1280      1290      

      740       750       760       770       780       790        
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
       ::::::::::  ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. .  .
NP_001 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
       1300      1310      1320      1330      1340      1350      

      800       810       820       830        
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
        ::::..:::::::.. :..::.::.. :::::::  :..
NP_001 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
        1360      1370      1380      1390     

>--
 initn: 922 init1: 376 opt: 883  Z-score: 779.8  bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::: .::.::::: ::::..: : ::::::::::::::::                
NP_001 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
             : : :::::.. .:: ::  :.:..            :::::: :. ::::: .
NP_001 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
                 50        60                    70        80      

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       : :.::: ::: .::.: .:..:  :::: .: ::....:  :.:.: :: ::::::.:.
NP_001 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
         90       100       110       120       130       140      

                190       200       210       220       230        
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
       :.::  ..  : :.:: :   :::::::::  :: ...::: .: :  .:. :..: ::.
NP_001 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
        150       160       170       180       190        200     

      240         250       260       270       280       290      
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
       :.:....  :  : ....:: : :....:  :: ...:: :. : ::::::. .   ::.
NP_001 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
         210       220       230       240       250       260     

        300       310       320       330         340       350    
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
        ..::.   ::  :. : ::..:...:   :: :  : : . .::   :.::. : . : 
NP_001 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
         270         280       290       300       310       320   

          360         370            380         390       400     
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
        .. :.  . ::...  .:      : .:.:  :  ::..   :    .:::  ..    
NP_001 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
           330       340       350       360       370       380   

                 410       420       430       440       450       
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
            : :  ..:  .:: :. :. .:: ..::..  :  :.. . :.:.:.::::: ..
NP_001 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
           390       400       410       420       430       440   

       460       470       480       490       500       510       
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
       ::                                                          
NP_001 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
           450       460       470       480       490       500   

>>XP_016885471 (OMIM: 300417) PREDICTED: G-protein coupl  (1395 aa)
 initn: 2409 init1: 1468 opt: 2043  Z-score: 1799.2  bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)

       10        20        30        40          50        60      
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
                                     .:  .:  :  ::: .: ... ..   .: 
XP_016 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
      530       540       550       560       570       580        

         70        80        90         100       110       120    
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
       :..   : .:  ..: ::.   : . : :.    ...: . : . ::.. .    :  : 
XP_016 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
      590       600          610       620       630       640     

           130       140        150             160       170      
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
         :.  .. . :: .  .   :. .::  .  :    :     .:.  ::.    ....:
XP_016 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
         650       660       670       680       690        700    

        180       190       200        210       220            230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
       :    .   :. .  :  :.   ::.:. :.   ..  ..::.  .: ::. ::     :
XP_016 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
          710       720       730       740       750       760    

              240        250       260       270       280         
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
       .   :   .:: ..  ::    .. ..: .   .:  ..:  ...:. : :: :...:. 
XP_016 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
          770       780         790       800       810       820  

     290       300       310       320               330           
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
         .   .:  ...   :...::  : ..   ..:          :::.    :.:.   :
XP_016 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
               830         840       850       860       870       

      340       350       360          370               380       
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
       :  : :::. .   .  :. ..  .   . ..   :. .:..:        :. .::.:.
XP_016 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
       880       890       900       910       920       930       

       390       400       410       420           430       440   
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
        ::::.. .:  : :. : :::.: .::::: :: . ::.    ... :.    ..  . 
XP_016 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
       940       950       960       970       980       990       

           450       460       470       480        490       500  
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
       :.::: :::::  ::: :. :: ::...  :   ..: : . : :::.:.::::.:::: 
XP_016 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
       1000      1010      1020      1030      1040      1050      

            510       520           530       540       550        
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
       .  ::: : ::: .:.::.    ::. .::.:. ::::::.:::::::::::::: ::::
XP_016 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
       1060      1070      1080      1090      1100      1110      

      560       570       580       590       600       610        
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
       ::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
XP_016 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
       1120      1130      1140      1150      1160      1170      

      620       630       640       650       660       670        
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
       :::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
XP_016 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
       1180      1190      1200      1210      1220      1230      

      680       690       700       710       720       730        
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
       ::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
XP_016 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
       1240      1250      1260      1270      1280      1290      

      740       750       760       770       780       790        
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
       ::::::::::  ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. .  .
XP_016 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
       1300      1310      1320      1330      1340      1350      

      800       810       820       830        
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
        ::::..:::::::.. :..::.::.. :::::::  :..
XP_016 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
        1360      1370      1380      1390     

>--
 initn: 922 init1: 376 opt: 883  Z-score: 779.8  bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::: .::.::::: ::::..: : ::::::::::::::::                
XP_016 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
             : : :::::.. .:: ::  :.:..            :::::: :. ::::: .
XP_016 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
                 50        60                    70        80      

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       : :.::: ::: .::.: .:..:  :::: .: ::....:  :.:.: :: ::::::.:.
XP_016 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
         90       100       110       120       130       140      

                190       200       210       220       230        
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
       :.::  ..  : :.:: :   :::::::::  :: ...::: .: :  .:. :..: ::.
XP_016 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
        150       160       170       180       190        200     

      240         250       260       270       280       290      
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
       :.:....  :  : ....:: : :....:  :: ...:: :. : ::::::. .   ::.
XP_016 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
         210       220       230       240       250       260     

        300       310       320       330         340       350    
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
        ..::.   ::  :. : ::..:...:   :: :  : : . .::   :.::. : . : 
XP_016 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
         270         280       290       300       310       320   

          360         370            380         390       400     
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
        .. :.  . ::...  .:      : .:.:  :  ::..   :    .:::  ..    
XP_016 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
           330       340       350       360       370       380   

                 410       420       430       440       450       
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
            : :  ..:  .:: :. :. .:: ..::..  :  :.. . :.:.:.::::: ..
XP_016 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
           390       400       410       420       430       440   

       460       470       480       490       500       510       
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
       ::                                                          
XP_016 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
           450       460       470       480       490       500   

>>NP_001092880 (OMIM: 300417) G-protein coupled receptor  (1395 aa)
 initn: 2409 init1: 1468 opt: 2043  Z-score: 1799.2  bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)

       10        20        30        40          50        60      
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
                                     .:  .:  :  ::: .: ... ..   .: 
NP_001 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
      530       540       550       560       570       580        

         70        80        90         100       110       120    
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
       :..   : .:  ..: ::.   : . : :.    ...: . : . ::.. .    :  : 
NP_001 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
      590       600          610       620       630       640     

           130       140        150             160       170      
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
         :.  .. . :: .  .   :. .::  .  :    :     .:.  ::.    ....:
NP_001 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
         650       660       670       680       690        700    

        180       190       200        210       220            230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
       :    .   :. .  :  :.   ::.:. :.   ..  ..::.  .: ::. ::     :
NP_001 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
          710       720       730       740       750       760    

              240        250       260       270       280         
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
       .   :   .:: ..  ::    .. ..: .   .:  ..:  ...:. : :: :...:. 
NP_001 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
          770       780         790       800       810       820  

     290       300       310       320               330           
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
         .   .:  ...   :...::  : ..   ..:          :::.    :.:.   :
NP_001 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
               830         840       850       860       870       

      340       350       360          370               380       
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
       :  : :::. .   .  :. ..  .   . ..   :. .:..:        :. .::.:.
NP_001 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
       880       890       900       910       920       930       

       390       400       410       420           430       440   
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
        ::::.. .:  : :. : :::.: .::::: :: . ::.    ... :.    ..  . 
NP_001 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
       940       950       960       970       980       990       

           450       460       470       480        490       500  
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
       :.::: :::::  ::: :. :: ::...  :   ..: : . : :::.:.::::.:::: 
NP_001 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
       1000      1010      1020      1030      1040      1050      

            510       520           530       540       550        
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
       .  ::: : ::: .:.::.    ::. .::.:. ::::::.:::::::::::::: ::::
NP_001 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
       1060      1070      1080      1090      1100      1110      

      560       570       580       590       600       610        
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
       ::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_001 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
       1120      1130      1140      1150      1160      1170      

      620       630       640       650       660       670        
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
       :::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_001 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
       1180      1190      1200      1210      1220      1230      

      680       690       700       710       720       730        
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
       ::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_001 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
       1240      1250      1260      1270      1280      1290      

      740       750       760       770       780       790        
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
       ::::::::::  ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. .  .
NP_001 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
       1300      1310      1320      1330      1340      1350      

      800       810       820       830        
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
        ::::..:::::::.. :..::.::.. :::::::  :..
NP_001 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
        1360      1370      1380      1390     

>--
 initn: 922 init1: 376 opt: 883  Z-score: 779.8  bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::: .::.::::: ::::..: : ::::::::::::::::                
NP_001 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
             : : :::::.. .:: ::  :.:..            :::::: :. ::::: .
NP_001 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
                 50        60                    70        80      

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       : :.::: ::: .::.: .:..:  :::: .: ::....:  :.:.: :: ::::::.:.
NP_001 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
         90       100       110       120       130       140      

                190       200       210       220       230        
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
       :.::  ..  : :.:: :   :::::::::  :: ...::: .: :  .:. :..: ::.
NP_001 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
        150       160       170       180       190        200     

      240         250       260       270       280       290      
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
       :.:....  :  : ....:: : :....:  :: ...:: :. : ::::::. .   ::.
NP_001 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
         210       220       230       240       250       260     

        300       310       320       330         340       350    
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
        ..::.   ::  :. : ::..:...:   :: :  : : . .::   :.::. : . : 
NP_001 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
         270         280       290       300       310       320   

          360         370            380         390       400     
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
        .. :.  . ::...  .:      : .:.:  :  ::..   :    .:::  ..    
NP_001 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
           330       340       350       360       370       380   

                 410       420       430       440       450       
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
            : :  ..:  .:: :. :. .:: ..::..  :  :.. . :.:.:.::::: ..
NP_001 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
           390       400       410       420       430       440   

       460       470       480       490       500       510       
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
       ::                                                          
NP_001 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
           450       460       470       480       490       500   

>>XP_016885470 (OMIM: 300417) PREDICTED: G-protein coupl  (1395 aa)
 initn: 2409 init1: 1468 opt: 2043  Z-score: 1799.2  bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)

       10        20        30        40          50        60      
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
                                     .:  .:  :  ::: .: ... ..   .: 
XP_016 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
      530       540       550       560       570       580        

         70        80        90         100       110       120    
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
       :..   : .:  ..: ::.   : . : :.    ...: . : . ::.. .    :  : 
XP_016 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
      590       600          610       620       630       640     

           130       140        150             160       170      
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
         :.  .. . :: .  .   :. .::  .  :    :     .:.  ::.    ....:
XP_016 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
         650       660       670       680       690        700    

        180       190       200        210       220            230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
       :    .   :. .  :  :.   ::.:. :.   ..  ..::.  .: ::. ::     :
XP_016 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
          710       720       730       740       750       760    

              240        250       260       270       280         
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
       .   :   .:: ..  ::    .. ..: .   .:  ..:  ...:. : :: :...:. 
XP_016 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
          770       780         790       800       810       820  

     290       300       310       320               330           
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
         .   .:  ...   :...::  : ..   ..:          :::.    :.:.   :
XP_016 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
               830         840       850       860       870       

      340       350       360          370               380       
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
       :  : :::. .   .  :. ..  .   . ..   :. .:..:        :. .::.:.
XP_016 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
       880       890       900       910       920       930       

       390       400       410       420           430       440   
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
        ::::.. .:  : :. : :::.: .::::: :: . ::.    ... :.    ..  . 
XP_016 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
       940       950       960       970       980       990       

           450       460       470       480        490       500  
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
       :.::: :::::  ::: :. :: ::...  :   ..: : . : :::.:.::::.:::: 
XP_016 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
       1000      1010      1020      1030      1040      1050      

            510       520           530       540       550        
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
       .  ::: : ::: .:.::.    ::. .::.:. ::::::.:::::::::::::: ::::
XP_016 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
       1060      1070      1080      1090      1100      1110      

      560       570       580       590       600       610        
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
       ::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
XP_016 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
       1120      1130      1140      1150      1160      1170      

      620       630       640       650       660       670        
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
       :::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
XP_016 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
       1180      1190      1200      1210      1220      1230      

      680       690       700       710       720       730        
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
       ::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
XP_016 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
       1240      1250      1260      1270      1280      1290      

      740       750       760       770       780       790        
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
       ::::::::::  ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. .  .
XP_016 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
       1300      1310      1320      1330      1340      1350      

      800       810       820       830        
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
        ::::..:::::::.. :..::.::.. :::::::  :..
XP_016 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
        1360      1370      1380      1390     

>--
 initn: 922 init1: 376 opt: 883  Z-score: 779.8  bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::: .::.::::: ::::..: : ::::::::::::::::                
XP_016 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
             : : :::::.. .:: ::  :.:..            :::::: :. ::::: .
XP_016 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
                 50        60                    70        80      

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       : :.::: ::: .::.: .:..:  :::: .: ::....:  :.:.: :: ::::::.:.
XP_016 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
         90       100       110       120       130       140      

                190       200       210       220       230        
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
       :.::  ..  : :.:: :   :::::::::  :: ...::: .: :  .:. :..: ::.
XP_016 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
        150       160       170       180       190        200     

      240         250       260       270       280       290      
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
       :.:....  :  : ....:: : :....:  :: ...:: :. : ::::::. .   ::.
XP_016 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
         210       220       230       240       250       260     

        300       310       320       330         340       350    
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
        ..::.   ::  :. : ::..:...:   :: :  : : . .::   :.::. : . : 
XP_016 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
         270         280       290       300       310       320   

          360         370            380         390       400     
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
        .. :.  . ::...  .:      : .:.:  :  ::..   :    .:::  ..    
XP_016 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
           330       340       350       360       370       380   

                 410       420       430       440       450       
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
            : :  ..:  .:: :. :. .:: ..::..  :  :.. . :.:.:.::::: ..
XP_016 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
           390       400       410       420       430       440   

       460       470       480       490       500       510       
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
       ::                                                          
XP_016 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
           450       460       470       480       490       500   

>>NP_055525 (OMIM: 300417) G-protein coupled receptor-as  (1395 aa)
 initn: 2409 init1: 1468 opt: 2043  Z-score: 1799.2  bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)

       10        20        30        40          50        60      
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
                                     .:  .:  :  ::: .: ... ..   .: 
NP_055 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
      530       540       550       560       570       580        

         70        80        90         100       110       120    
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
       :..   : .:  ..: ::.   : . : :.    ...: . : . ::.. .    :  : 
NP_055 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
      590       600          610       620       630       640     

           130       140        150             160       170      
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
         :.  .. . :: .  .   :. .::  .  :    :     .:.  ::.    ....:
NP_055 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
         650       660       670       680       690        700    

        180       190       200        210       220            230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
       :    .   :. .  :  :.   ::.:. :.   ..  ..::.  .: ::. ::     :
NP_055 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
          710       720       730       740       750       760    

              240        250       260       270       280         
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
       .   :   .:: ..  ::    .. ..: .   .:  ..:  ...:. : :: :...:. 
NP_055 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
          770       780         790       800       810       820  

     290       300       310       320               330           
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
         .   .:  ...   :...::  : ..   ..:          :::.    :.:.   :
NP_055 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
               830         840       850       860       870       

      340       350       360          370               380       
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
       :  : :::. .   .  :. ..  .   . ..   :. .:..:        :. .::.:.
NP_055 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
       880       890       900       910       920       930       

       390       400       410       420           430       440   
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
        ::::.. .:  : :. : :::.: .::::: :: . ::.    ... :.    ..  . 
NP_055 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
       940       950       960       970       980       990       

           450       460       470       480        490       500  
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
       :.::: :::::  ::: :. :: ::...  :   ..: : . : :::.:.::::.:::: 
NP_055 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
       1000      1010      1020      1030      1040      1050      

            510       520           530       540       550        
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
       .  ::: : ::: .:.::.    ::. .::.:. ::::::.:::::::::::::: ::::
NP_055 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
       1060      1070      1080      1090      1100      1110      

      560       570       580       590       600       610        
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
       ::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_055 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
       1120      1130      1140      1150      1160      1170      

      620       630       640       650       660       670        
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
       :::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_055 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
       1180      1190      1200      1210      1220      1230      

      680       690       700       710       720       730        
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
       ::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_055 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
       1240      1250      1260      1270      1280      1290      

      740       750       760       770       780       790        
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
       ::::::::::  ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. .  .
NP_055 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
       1300      1310      1320      1330      1340      1350      

      800       810       820       830        
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
        ::::..:::::::.. :..::.::.. :::::::  :..
NP_055 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
        1360      1370      1380      1390     

>--
 initn: 922 init1: 376 opt: 883  Z-score: 779.8  bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)

               10        20        30        40        50        60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
       ::::::: .::.::::: ::::..: : ::::::::::::::::                
NP_055 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
             : : :::::.. .:: ::  :.:..            :::::: :. ::::: .
NP_055 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
                 50        60                    70        80      

              130       140       150       160       170       180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
       : :.::: ::: .::.: .:..:  :::: .: ::....:  :.:.: :: ::::::.:.
NP_055 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
         90       100       110       120       130       140      

                190       200       210       220       230        
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
       :.::  ..  : :.:: :   :::::::::  :: ...::: .: :  .:. :..: ::.
NP_055 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
        150       160       170       180       190        200     

      240         250       260       270       280       290      
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
       :.:....  :  : ....:: : :....:  :: ...:: :. : ::::::. .   ::.
NP_055 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
         210       220       230       240       250       260     

        300       310       320       330         340       350    
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
        ..::.   ::  :. : ::..:...:   :: :  : : . .::   :.::. : . : 
NP_055 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
         270         280       290       300       310       320   

          360         370            380         390       400     
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
        .. :.  . ::...  .:      : .:.:  :  ::..   :    .:::  ..    
NP_055 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
           330       340       350       360       370       380   

                 410       420       430       440       450       
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
            : :  ..:  .:: :. :. .:: ..::..  :  :.. . :.:.:.::::: ..
NP_055 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
           390       400       410       420       430       440   

       460       470       480       490       500       510       
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
       ::                                                          
NP_055 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
           450       460       470       480       490       500   




838 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:00:25 2016 done: Fri Nov  4 14:00:27 2016
 Total Scan time: 11.180 Total Display time:  0.330

Function used was FASTA [36.3.4 Apr, 2011]
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