Result of FASTA (omim) for pF1KB8357
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8357, 263 aa
  1>>>pF1KB8357 263 - 263 aa - 263 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2125+/-0.000318; mu= 3.5159+/- 0.020
 mean_var=197.5668+/-41.612, 0's: 0 Z-trim(122.6): 6  B-trim: 1235 in 1/57
 Lambda= 0.091247
 statistics sampled from 41022 (41028) to 41022 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.481), width:  16
 Scan time:  5.700

The best scores are:                                      opt bits E(85289)
NP_060560 (OMIM: 611624) adaptin ear-binding coat- ( 263) 1821 251.2 1.4e-66
NP_001138750 (OMIM: 611624) adaptin ear-binding co ( 237) 1604 222.6 5.2e-58
NP_001138749 (OMIM: 611624) adaptin ear-binding co ( 273) 1532 213.2 4.1e-55
XP_011540069 (OMIM: 611624) PREDICTED: adaptin ear ( 220) 1159 164.0 2.1e-40
XP_016857210 (OMIM: 611624) PREDICTED: adaptin ear ( 185) 1118 158.5 7.9e-39
NP_056324 (OMIM: 611623,615833) adaptin ear-bindin ( 275) 1082 153.9 2.8e-37


>>NP_060560 (OMIM: 611624) adaptin ear-binding coat-asso  (263 aa)
 initn: 1821 init1: 1821 opt: 1821  Z-score: 1316.2  bits: 251.2 E(85289): 1.4e-66
Smith-Waterman score: 1821; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KB8 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 STGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 STGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIW
              190       200       210       220       230       240

              250       260   
pF1KB8 GDFTKSTGSTSSQTQPGTGWVQF
       :::::::::::::::::::::::
NP_060 GDFTKSTGSTSSQTQPGTGWVQF
              250       260   

>>NP_001138750 (OMIM: 611624) adaptin ear-binding coat-a  (237 aa)
 initn: 1622 init1: 1604 opt: 1604  Z-score: 1162.4  bits: 222.6 E(85289): 5.2e-58
Smith-Waterman score: 1604; 100.0% identity (100.0% similar) in 232 aa overlap (32-263:6-237)

              10        20        30        40        50        60 
pF1KB8 EESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLED
                                     ::::::::::::::::::::::::::::::
NP_001                          MEESGAAEWQLDQPSWSGRLRITAKGQMAYIKLED
                                        10        20        30     

              70        80        90       100       110       120 
pF1KB8 RTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVA
          40        50        60        70        80        90     

             130       140       150       160       170       180 
pF1KB8 LQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPAS
         100       110       120       130       140       150     

             190       200       210       220       230       240 
pF1KB8 TGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWG
         160       170       180       190       200       210     

             250       260   
pF1KB8 DFTKSTGSTSSQTQPGTGWVQF
       ::::::::::::::::::::::
NP_001 DFTKSTGSTSSQTQPGTGWVQF
         220       230       

>>NP_001138749 (OMIM: 611624) adaptin ear-binding coat-a  (273 aa)
 initn: 1515 init1: 1515 opt: 1532  Z-score: 1110.4  bits: 213.2 E(85289): 4.1e-55
Smith-Waterman score: 1532; 88.8% identity (92.3% similar) in 260 aa overlap (1-259:1-257)

               10        20        30        40        50        60
pF1KB8 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 STGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIW
       ::::::::::::::::::::::::::::::::::::::::::   :.   .:. : :   
NP_001 STGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSDQLPA---RPSQAQAGSS
              190       200       210       220          230       

               250       260               
pF1KB8 GDFTKSTGS-TSSQTQPGTGWVQF            
       .:..      ::... :  :                
NP_001 SDLSTVFPHVTSGKALPHLGQRKEDEALLSWPVFGA
       240       250       260       270   

>>XP_011540069 (OMIM: 611624) PREDICTED: adaptin ear-bin  (220 aa)
 initn: 1142 init1: 1142 opt: 1159  Z-score: 846.3  bits: 164.0 E(85289): 2.1e-40
Smith-Waterman score: 1159; 86.0% identity (90.3% similar) in 207 aa overlap (54-259:1-204)

            30        40        50        60        70        80   
pF1KB8 RATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQAPVDQFPGTAVES
                                     ::::::::::::::::::::::::::::::
XP_011                               MAYIKLEDRTSGELFAQAPVDQFPGTAVES
                                             10        20        30

            90       100       110       120       130       140   
pF1KB8 VTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPD
               40        50        60        70        80        90

           150       160       170       180       190       200   
pF1KB8 QGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPP
              100       110       120       130       140       150

           210       220       230       240        250       260  
pF1KB8 GEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGS-TSSQTQPGTGWVQ
       :::::::::::::::::::   :.   .:. : :   .:..      ::... :  :   
XP_011 GEQLAVGGSLVQPAVAPSSDQLPA---RPSQAQAGSSSDLSTVFPHVTSGKALPHLGQRK
              160       170          180       190       200       

                    
pF1KB8 F            
                    
XP_011 EDEALLSWPVFGA
       210       220

>>XP_016857210 (OMIM: 611624) PREDICTED: adaptin ear-bin  (185 aa)
 initn: 1118 init1: 1118 opt: 1118  Z-score: 818.1  bits: 158.5 E(85289): 7.9e-39
Smith-Waterman score: 1118; 100.0% identity (100.0% similar) in 163 aa overlap (1-163:1-163)

               10        20        30        40        50        60
pF1KB8 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPA
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_016 ALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIAVGLGNINRRCSCTLATA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 STGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIW
                                                                   
XP_016 QSCHC                                                       
                                                                   

>>NP_056324 (OMIM: 611623,615833) adaptin ear-binding co  (275 aa)
 initn: 1185 init1: 928 opt: 1082  Z-score: 790.2  bits: 153.9 E(85289): 2.8e-37
Smith-Waterman score: 1160; 62.3% identity (82.8% similar) in 273 aa overlap (6-263:7-275)

                10        20        30        40        50         
pF1KB8  MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKL
             ::::::::::: ::::::::.::::::..:.::::.:.::::::.::. :::::
NP_056 MATELEYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKTAYIKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 EDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFN
       ::..::::::::::.:.:: :::.::::::::::::.::.:: ::::::: :::::::::
NP_056 EDKVSGELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFTDRGDAFDFN
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 VALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRP
       :.::::::::::. :..:..:. :  ::::::::::::::: :.:. .:.:.:..::.  
NP_056 VSLQDHFKWVKQESEISKESQEMDARPKLDLGFKEGQTIKLCIGNITNKKGGASKPRT--
              130       140       150       160       170          

     180       190       200       210       220                   
pF1KB8 ASTGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGG-------------AP
       :  :::::::::::::..  ::::. ..:... .. : .  :. :             ::
NP_056 ARGGGLSLLPPPPGGKVT--IPPPSSSVAISNHVTPPPIPKSNHGGSDADILLDLDSPAP
      180       190         200       210       220       230      

        230         240       250       260   
pF1KB8 VPWPQPNPATA--DIWGDFTKSTGSTSSQTQPGTGWVQF
       :  : :.:...  :.::::. ...:. .:.   ..::::
NP_056 VTTPAPTPVSVSNDLWGDFSTASSSVPNQAPQPSNWVQF
        240       250       260       270     




263 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:04:27 2016 done: Fri Nov  4 12:04:28 2016
 Total Scan time:  5.700 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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