Result of FASTA (omim) for pF1KB8320
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8320, 129 aa
  1>>>pF1KB8320 129 - 129 aa - 129 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5778+/-0.000388; mu= 15.0844+/- 0.024
 mean_var=71.4997+/-15.608, 0's: 0 Z-trim(114.5): 278  B-trim: 2645 in 3/51
 Lambda= 0.151678
 statistics sampled from 23921 (24311) to 23921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.285), width:  16
 Scan time:  3.660

The best scores are:                                      opt bits E(85289)
NP_056358 (OMIM: 179508) ras-related protein Rab-1 ( 129)  830 190.1 8.3e-49
XP_005264525 (OMIM: 179508) PREDICTED: ras-related ( 173)  426 101.8 4.2e-22
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205)  426 101.9 4.7e-22
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201)  390 94.0 1.1e-19
XP_016873867 (OMIM: 612565) PREDICTED: ras-related ( 237)  390 94.1 1.2e-19
XP_011519971 (OMIM: 613532) PREDICTED: ras-related ( 122)  312 76.7 1.1e-14
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207)  312 77.0 1.5e-14
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207)  308 76.1 2.8e-14
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215)  308 76.1 2.9e-14
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203)  298 73.9 1.3e-13
NP_001161078 (OMIM: 604199) ras-related protein Ra ( 152)  295 73.1 1.6e-13
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201)  295 73.2   2e-13
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200)  288 71.7 5.7e-13
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220)  242 61.7 6.5e-10
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220)  242 61.7 6.5e-10
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219)  241 61.5 7.6e-10
NP_001304844 (OMIM: 612829) ras-related protein Ra ( 225)  241 61.5 7.7e-10
NP_612462 (OMIM: 612829) ras-related protein Rab-3 ( 227)  241 61.5 7.8e-10
NP_001193765 (OMIM: 605570) ras-related protein Ra ( 155)  237 60.4 1.1e-09
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219)  238 60.8 1.2e-09
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219)  238 60.8 1.2e-09
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216)  237 60.6 1.4e-09
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218)  237 60.6 1.4e-09
XP_011520750 (OMIM: 605455) PREDICTED: ras-related ( 231)  222 57.3 1.4e-08
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256)  222 57.4 1.5e-08
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203)  220 56.8 1.7e-08
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203)  220 56.8 1.7e-08
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203)  220 56.8 1.7e-08
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203)  220 56.8 1.7e-08
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212)  220 56.9 1.8e-08
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216)  220 56.9 1.8e-08
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244)  215 55.8 4.2e-08
NP_001243341 (OMIM: 602207,614222) ras-related pro ( 142)  211 54.7 5.3e-08
NP_001243340 (OMIM: 602207,614222) ras-related pro ( 197)  211 54.9 6.6e-08
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206)  211 54.9 6.9e-08
NP_001243339 (OMIM: 602207,614222) ras-related pro ( 235)  211 54.9 7.5e-08
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213)  206 53.8 1.5e-07
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223)  206 53.8 1.5e-07
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215)  199 52.3 4.4e-07
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218)  199 52.3 4.4e-07
NP_112586 (OMIM: 605950,615222) ras-related protei ( 229)  196 51.6 7.2e-07
XP_011530601 (OMIM: 605950,615222) PREDICTED: ras- ( 277)  196 51.7 8.2e-07
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190)  194 51.1 8.5e-07
NP_004785 (OMIM: 300333) ras-related protein Rab-3 ( 237)  194 51.2   1e-06
XP_011524433 (OMIM: 603869) PREDICTED: ras-related ( 182)  189 50.0 1.8e-06
XP_006722581 (OMIM: 603869) PREDICTED: ras-related ( 182)  189 50.0 1.8e-06
XP_005266790 (OMIM: 603869) PREDICTED: ras-related ( 218)  189 50.1   2e-06
XP_016881402 (OMIM: 603869) PREDICTED: ras-related ( 218)  189 50.1   2e-06
NP_004154 (OMIM: 603869) ras-related protein Rab-2 ( 218)  189 50.1   2e-06
XP_016881403 (OMIM: 603869) PREDICTED: ras-related ( 218)  189 50.1   2e-06


>>NP_056358 (OMIM: 179508) ras-related protein Rab-1A is  (129 aa)
 initn: 830 init1: 830 opt: 830  Z-score: 997.2  bits: 190.1 E(85289): 8.3e-49
Smith-Waterman score: 830; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
               70        80        90       100       110       120

                
pF1KB8 VKQSGGGCC
       :::::::::
NP_056 VKQSGGGCC
                

>>XP_005264525 (OMIM: 179508) PREDICTED: ras-related pro  (173 aa)
 initn: 425 init1: 423 opt: 426  Z-score: 517.8  bits: 101.8 E(85289): 4.2e-22
Smith-Waterman score: 648; 72.7% identity (72.7% similar) in 161 aa overlap (13-129:13-173)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
               10        20        30        40        50        60

                                                           70      
pF1KB8 KLQIE--------------------------------------------FADSLGIPFLE
       :::::                                            :::::::::::
XP_005 KLQIESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLE
               70        80        90       100       110       120

         80        90       100       110       120         
pF1KB8 TSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
              130       140       150       160       170   

>>NP_004152 (OMIM: 179508) ras-related protein Rab-1A is  (205 aa)
 initn: 816 init1: 423 opt: 426  Z-score: 516.9  bits: 101.9 E(85289): 4.7e-22
Smith-Waterman score: 426; 71.0% identity (84.0% similar) in 100 aa overlap (30-129:111-205)

                10        20        30        40        50         
pF1KB8  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT
                                     :.:... ..  ...   :.  . . .:  :
NP_004 YRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGN-KCDLTTKKV-VDYTT
               90       100       110       120        130         

      60        70        80        90       100       110         
pF1KB8 IKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
        :   :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AK---EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
      140          150       160       170       180       190     

     120         
pF1KB8 PVKQSGGGCC
       ::::::::::
NP_004 PVKQSGGGCC
         200     

>--
 initn: 416 init1: 407 opt: 407  Z-score: 494.5  bits: 97.8 E(85289): 8.4e-21
Smith-Waterman score: 407; 100.0% identity (100.0% similar) in 64 aa overlap (1-64:1-64)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
NP_004 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
               70        80        90       100       110       120

>>NP_112243 (OMIM: 612565) ras-related protein Rab-1B [H  (201 aa)
 initn: 641 init1: 390 opt: 390  Z-score: 474.5  bits: 94.0 E(85289): 1.1e-19
Smith-Waterman score: 390; 100.0% identity (100.0% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112    MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
NP_112 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKL
        60        70        80        90       100       110       

>--
 initn: 275 init1: 265 opt: 367  Z-score: 447.3  bits: 89.0 E(85289): 3.6e-18
Smith-Waterman score: 367; 61.0% identity (83.0% similar) in 100 aa overlap (30-129:108-201)

                10        20        30        40        50         
pF1KB8  MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT
                                     :.:... ..  ... . :.  . . .:. :
NP_112 YRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKS-DLTTKKV-VDNTT
        80        90       100       110       120        130      

      60        70        80        90       100       110         
pF1KB8 IKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
        :   :::::::::::::::::::::::.::::::::::::::::..:: :. :.::.::
NP_112 AK---EFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGG-ERPNLKIDST
            140       150       160       170       180        190 

     120         
pF1KB8 PVKQSGGGCC
       ::: .:::::
NP_112 PVKPAGGGCC
             200 

>>XP_016873867 (OMIM: 612565) PREDICTED: ras-related pro  (237 aa)
 initn: 641 init1: 390 opt: 390  Z-score: 473.6  bits: 94.1 E(85289): 1.2e-19
Smith-Waterman score: 390; 100.0% identity (100.0% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016    MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
XP_016 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKL
        60        70        80        90       100       110       

>--
 initn: 275 init1: 265 opt: 361  Z-score: 439.3  bits: 87.8 E(85289): 9.9e-18
Smith-Waterman score: 361; 84.6% identity (95.4% similar) in 65 aa overlap (65-129:174-237)

           40        50        60        70        80        90    
pF1KB8 TYTESYISTIGVDFKIRTIELDGKTIKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAA
                                     :::::::::::::::::::::::.::::::
XP_016 CPGSGRWGLLPLTCSPLLFSPLLFSPLPCQEFADSLGIPFLETSAKNATNVEQAFMTMAA
           150       160       170       180       190       200   

          100       110       120         
pF1KB8 EIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
       ::::::::::..:: :. :.::.::::: .:::::
XP_016 EIKKRMGPGAASGG-ERPNLKIDSTPVKPAGGGCC
           210        220       230       

>>XP_011519971 (OMIM: 613532) PREDICTED: ras-related pro  (122 aa)
 initn: 324 init1: 312 opt: 312  Z-score: 384.9  bits: 76.7 E(85289): 1.1e-14
Smith-Waterman score: 312; 75.4% identity (91.8% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :   :::::::::::::::::.:::.::..:... ..:::::.:::::::::::: :
XP_011    MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
XP_011 KLQIWDTAGQERFRTITTAYYRGAMPCHHYLLPHHLHNIHCCGSSPCHPPDHHSASWPER
        60        70        80        90       100       110       

>>NP_057614 (OMIM: 613532) ras-related protein Rab-8B [H  (207 aa)
 initn: 402 init1: 312 opt: 312  Z-score: 382.1  bits: 77.0 E(85289): 1.5e-14
Smith-Waterman score: 312; 75.4% identity (91.8% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :   :::::::::::::::::.:::.::..:... ..:::::.:::::::::::: :
NP_057    MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
NP_057 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERM
        60        70        80        90       100       110       

>>NP_005361 (OMIM: 165040) ras-related protein Rab-8A [H  (207 aa)
 initn: 423 init1: 308 opt: 308  Z-score: 377.3  bits: 76.1 E(85289): 2.8e-14
Smith-Waterman score: 308; 73.8% identity (91.8% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :   :::::::::::::::::.:.:.::..:... ..:::::.:::::::::::: :
NP_005    MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
NP_005 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKM
        60        70        80        90       100       110       

>>XP_011526322 (OMIM: 165040) PREDICTED: ras-related pro  (215 aa)
 initn: 401 init1: 308 opt: 308  Z-score: 377.1  bits: 76.1 E(85289): 2.9e-14
Smith-Waterman score: 308; 73.8% identity (91.8% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :   :::::::::::::::::.:.:.::..:... ..:::::.:::::::::::: :
XP_011    MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       ::::                                                        
XP_011 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKM
        60        70        80        90       100       110       

>>NP_002861 (OMIM: 602672) ras-related protein Rab-13 is  (203 aa)
 initn: 365 init1: 294 opt: 298  Z-score: 365.6  bits: 73.9 E(85289): 1.3e-13
Smith-Waterman score: 298; 67.2% identity (93.4% similar) in 61 aa overlap (4-64:1-61)

               10        20        30        40        50        60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
          :   ::.::::::::::::::.::..:::.:.....::::::.::::::....:: :
NP_002    MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
       :::.                                                        
NP_002 KLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERL
        60        70        80        90       100       110       




129 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:43:18 2016 done: Fri Nov  4 11:43:19 2016
 Total Scan time:  3.660 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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