Result of FASTA (omim) for pF1KB8238
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8238, 297 aa
  1>>>pF1KB8238 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0971+/-0.000481; mu= -2.3917+/- 0.030
 mean_var=202.3882+/-40.486, 0's: 0 Z-trim(115.0): 61  B-trim: 144 in 2/53
 Lambda= 0.090153
 statistics sampled from 25056 (25115) to 25056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.294), width:  16
 Scan time:  6.020

The best scores are:                                      opt bits E(85289)
NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 1858 254.3 2.2e-67
XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4  ( 293) 1564 216.0   7e-56
NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 1564 216.0   7e-56
NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 1354 188.6 9.2e-48
XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4  ( 154)  937 134.3 1.5e-31
NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288)  785 114.7 2.2e-25
NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287)  779 113.9 3.7e-25
XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2  ( 319)  779 113.9 4.1e-25
XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2  ( 260)  773 113.1 5.9e-25
NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288)  773 113.1 6.4e-25
XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2  ( 320)  773 113.2   7e-25
XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2  ( 320)  773 113.2   7e-25
XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282)  764 112.0 1.4e-24
NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo  ( 288)  764 112.0 1.4e-24
XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2  ( 277)  721 106.4 6.8e-23
XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2  ( 309)  721 106.4 7.4e-23
XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2  ( 317)  717 105.9 1.1e-22
XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3  ( 279)  707 104.5 2.4e-22
XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3  ( 279)  707 104.5 2.4e-22
XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3  ( 287)  707 104.5 2.5e-22
XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3  ( 281)  697 103.2 5.9e-22
XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3  ( 281)  697 103.2 5.9e-22
XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3  ( 281)  697 103.2 5.9e-22
XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3  ( 281)  697 103.2 5.9e-22
XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3  ( 289)  697 103.2 6.1e-22
NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289)  697 103.2 6.1e-22
XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3  ( 269)  650 97.1   4e-20
NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277)  650 97.1 4.1e-20
XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2  ( 213)  606 91.3 1.7e-18
NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2  ( 251)  607 91.5 1.8e-18
XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329)  607 91.6 2.3e-18
XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2  ( 214)  600 90.6   3e-18
XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3  ( 192)  552 84.3 2.1e-16
XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3  ( 252)  552 84.4 2.6e-16
XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3  ( 244)  531 81.6 1.7e-15
XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287)  393 63.7 4.8e-10
XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287)  393 63.7 4.8e-10
XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287)  393 63.7 4.8e-10
XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287)  393 63.7 4.8e-10
NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo  ( 287)  393 63.7 4.8e-10
XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313)  393 63.7 5.2e-10
XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3  ( 155)  386 62.6 5.5e-10
XP_016874477 (OMIM: 132350) PREDICTED: syntaxin-2  ( 167)  343 57.1 2.8e-08
XP_016874476 (OMIM: 132350) PREDICTED: syntaxin-2  ( 199)  343 57.1 3.2e-08
XP_016874475 (OMIM: 132350) PREDICTED: syntaxin-2  ( 200)  343 57.1 3.3e-08
NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276)  294 50.8 3.5e-06
NP_003560 (OMIM: 603217) syntaxin-7 isoform a [Hom ( 261)  279 48.9 1.3e-05
NP_001313507 (OMIM: 603217) syntaxin-7 isoform a [ ( 261)  279 48.9 1.3e-05
NP_001313508 (OMIM: 603217) syntaxin-7 isoform a [ ( 261)  279 48.9 1.3e-05
NP_001313509 (OMIM: 603217) syntaxin-7 isoform b [ ( 239)  244 44.3 0.00028


>>NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Homo sa  (297 aa)
 initn: 1858 init1: 1858 opt: 1858  Z-score: 1330.8  bits: 254.3 E(85289): 2.2e-67
Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
              190       200       210       220       230       240

              250       260       270       280       290       
pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
              250       260       270       280       290       

>>XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 isof  (293 aa)
 initn: 1560 init1: 1560 opt: 1564  Z-score: 1124.3  bits: 216.0 E(85289): 7e-56
Smith-Waterman score: 1564; 96.3% identity (97.0% similar) in 267 aa overlap (31-297:32-293)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
                                     :. :: : .     ::::::::::::::::
XP_005 TARTKRTRSGSRWWCTRARHGWGARTRSSSTSPLGHPPQ-----VRTIRQTIVKLGNKVQ
              10        20        30        40             50      

               70        80        90       100       110       120
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
        180       190       200       210       220       230      

              250       260       270       280       290       
pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
        240       250       260       270       280       290   

>>NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [Homo  (295 aa)
 initn: 1560 init1: 1560 opt: 1564  Z-score: 1124.2  bits: 216.0 E(85289): 7e-56
Smith-Waterman score: 1564; 96.3% identity (97.0% similar) in 267 aa overlap (31-297:34-295)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
                                     :. :: : .     ::::::::::::::::
NP_001 TARTKRTRSGSRWWCTRARHGWGARTRSSSTSPLGHPPQ-----VRTIRQTIVKLGNKVQ
            10        20        30        40             50        

               70        80        90       100       110       120
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG
      120       130       140       150       160       170        

              190       200       210       220       230       240
pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR
      180       190       200       210       220       230        

              250       260       270       280       290       
pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
      240       250       260       270       280       290     

>>NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [Homo  (219 aa)
 initn: 1354 init1: 1354 opt: 1354  Z-score: 978.5  bits: 188.6 E(85289): 9.2e-48
Smith-Waterman score: 1354; 100.0% identity (100.0% similar) in 219 aa overlap (79-297:1-219)

       50        60        70        80        90       100        
pF1KB8 RQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQK
                                     ::::::::::::::::::::::::::::::
NP_001                               MKQELQNLRDEIKQLGREIRLQLKAIEPQK
                                             10        20        30

      110       120       130       140       150       160        
pF1KB8 EEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMV
               40        50        60        70        80        90

      170       180       190       200       210       220        
pF1KB8 SDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLA
              100       110       120       130       140       150

      230       240       250       260       270       280        
pF1KB8 TEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLA
              160       170       180       190       200       210

      290       
pF1KB8 VIIGVTVVG
       :::::::::
NP_001 VIIGVTVVG
                

>>XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 isof  (154 aa)
 initn: 937 init1: 937 opt: 937  Z-score: 687.6  bits: 134.3 E(85289): 1.5e-31
Smith-Waterman score: 937; 100.0% identity (100.0% similar) in 154 aa overlap (144-297:1-154)

           120       130       140       150       160       170   
pF1KB8 NYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEEL
                                     ::::::::::::::::::::::::::::::
XP_011                               MQSEYREKNVERIRRQLKITNAGMVSDEEL
                                             10        20        30

           180       190       200       210       220       230   
pF1KB8 EQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEM
               40        50        60        70        80        90

           240       250       260       270       280       290   
pF1KB8 QGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGV
              100       110       120       130       140       150

           
pF1KB8 TVVG
       ::::
XP_011 TVVG
           

>>NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Homo s  (288 aa)
 initn: 769 init1: 507 opt: 785  Z-score: 576.8  bits: 114.7 E(85289): 2.2e-25
Smith-Waterman score: 785; 45.7% identity (76.8% similar) in 293 aa overlap (1-292:1-284)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
       :.:::.::: . ::.:..:   ::..:     :.    .:::..:. ::  : :....:.
NP_004 MKDRTQELRTAKDSDDDDD---VAVTVD--RDRFM---DEFFEQVEEIRGFIDKIAENVE
               10           20          30           40        50  

               70        80        90       100        110         
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKE-EADENYNSVN
       :..... .:::.: :.:. :.::..: ..::. . ..: .::.:: . : :   : .:..
NP_004 EVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSAD
             60        70        80        90       100       110  

     120       130       140       150       160       170         
pF1KB8 TRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDS
        :.:::::..::..:::.... :. ::.:::.   ::.:::.::.   .: ::::.::.:
NP_004 LRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS-EELEDMLES
            120       130       140       150       160        170 

     180       190       200       210       220       230         
pF1KB8 GQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMIN
       :.  .:.:.:. :.....:::.:: .::::: .:: :::::::.:  .:  :: :::::.
NP_004 GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMID
             180       190       200       210       220       230 

     240       250       260       270       280       290       
pF1KB8 RIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       ::: :.  ..:::::.   .: :.. :.:::.::..: ::  :  ...:  .:     
NP_004 RIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA 
             240       250       260       270       280         

>>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa  (287 aa)
 initn: 764 init1: 564 opt: 779  Z-score: 572.6  bits: 113.9 E(85289): 3.7e-25
Smith-Waterman score: 780; 44.1% identity (76.4% similar) in 297 aa overlap (1-295:1-286)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
       ::::  .:        ..: . :..: .          ..:::.:. ::..: :. . :.
NP_001 MRDRLPDLTA---CRKNDDGDTVVVVEKDHFM------DDFFHQVEEIRNSIDKITQYVE
               10           20              30        40        50 

               70        80        90       100       110          
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSV
       :..:..  ::..: :: ..:.::..:  :::. . .:: .::::: :. . ::  : .::
NP_001 EVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSV
              60        70        80        90        100       110

      120       130       140       150       160       170        
pF1KB8 NTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLD
       . :.:.:::.:::..::: . . :  :. .::..  ::.:::.::.   ..:.:::.::.
NP_001 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLE
              120       130       140       150        160         

      180       190       200       210       220       230        
pF1KB8 SGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMI
       ::.  .:.:.:..:.:.:::::::: .::..:..:: ::::::..:  .:  :: :::::
NP_001 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI
     170       180       190       200       210       220         

      240       250       260       270       280       290       
pF1KB8 NRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       : ::.:.....::::...:..: :.. :.:::.: ..: ::: . .:.:..:...:.  
NP_001 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 
     230       240       250       260       270       280        

>>XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 isof  (319 aa)
 initn: 745 init1: 564 opt: 779  Z-score: 571.9  bits: 113.9 E(85289): 4.1e-25
Smith-Waterman score: 779; 47.5% identity (81.9% similar) in 259 aa overlap (39-295:62-318)

       10        20        30        40        50        60        
pF1KB8 RQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVT
                                     ..:::.:. ::..: :. . :.:..:..  
XP_016 SAWCLIQSTCQCRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI
              40        50        60        70        80        90 

       70        80        90       100       110         120      
pF1KB8 ILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSVNTRMRKTQ
       ::..: :: ..:.::..:  :::. . .:: .::::: :. . ::  : .::. :.:.::
XP_016 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSVDLRIRRTQ
             100       110       120        130       140       150

        130       140       150       160       170       180      
pF1KB8 HGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFV
       :.:::..::: . . :  :. .::..  ::.:::.::.   ..:.:::.::.::.  .:.
XP_016 HSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFT
              160       170       180        190       200         

        190       200       210       220       230       240      
pF1KB8 SNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNIL
       :.:..:.:.:::::::: .::..:..:: ::::::..:  .:  :: :::::: ::.:..
XP_016 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM
     210       220       230       240       250       260         

        250       260       270       280       290       
pF1KB8 SSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
       ...::::...:..: :.. :.:::.: ..: ::: . .:.:..:...:.  
XP_016 NATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 
     270       280       290       300       310          

>>XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 isof  (260 aa)
 initn: 736 init1: 555 opt: 773  Z-score: 569.0  bits: 113.1 E(85289): 5.9e-25
Smith-Waterman score: 773; 48.1% identity (81.9% similar) in 260 aa overlap (39-295:2-258)

       10        20        30        40        50        60        
pF1KB8 RQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVT
                                     ..:::.:. ::..: :. . :.:..:..  
XP_016                              MDDFFHQVEEIRNSIDKITQYVEEVKKNHSI
                                            10        20        30 

       70        80        90       100       110         120      
pF1KB8 ILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSVNTRMRKTQ
       ::..: :: ..:.::..:  :::. . .:: .::::: :. . ::  : .::. :.:.::
XP_016 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSVDLRIRRTQ
              40        50        60         70        80        90

        130       140       150       160       170       180      
pF1KB8 HGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFV
       :.:::..::: . . :  :. .::..  ::.:::.::.   ..:.:::.::.::.  .:.
XP_016 HSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFT
              100       110       120        130       140         

        190       200       210       220       230       240      
pF1KB8 SNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNIL
       :.:..:.:.:::::::: .::..:..:: ::::::..:  .:  :: :::::: ::.:..
XP_016 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM
     150       160       170       180       190       200         

        250       260       270        280       290       
pF1KB8 SSADYVERGQEHVKTALENQKKARKKK-VLIAICVSITVVLLAVIIGVTVVG
       ...::::...:..: :.. :.:::.:: ..::. : . :...:.:::..:  
XP_016 NATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV-VLVAIIALIIGLSVGK
     210       220       230       240        250       260

>>NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Homo sa  (288 aa)
 initn: 755 init1: 555 opt: 773  Z-score: 568.4  bits: 113.1 E(85289): 6.4e-25
Smith-Waterman score: 774; 44.6% identity (76.5% similar) in 298 aa overlap (1-295:1-286)

               10        20        30        40        50        60
pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ
       ::::  .:        ..: . :..: .          ..:::.:. ::..: :. . :.
NP_919 MRDRLPDLTA---CRKNDDGDTVVVVEKDHFM------DDFFHQVEEIRNSIDKITQYVE
               10           20              30        40        50 

               70        80        90       100       110          
pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSV
       :..:..  ::..: :: ..:.::..:  :::. . .:: .::::: :. . ::  : .::
NP_919 EVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSV
              60        70        80        90        100       110

      120       130       140       150       160       170        
pF1KB8 NTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLD
       . :.:.:::.:::..::: . . :  :. .::..  ::.:::.::.   ..:.:::.::.
NP_919 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLE
              120       130       140       150        160         

      180       190       200       210       220       230        
pF1KB8 SGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMI
       ::.  .:.:.:..:.:.:::::::: .::..:..:: ::::::..:  .:  :: :::::
NP_919 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI
     170       180       190       200       210       220         

      240       250       260       270        280       290       
pF1KB8 NRIEKNILSSADYVERGQEHVKTALENQKKARKKK-VLIAICVSITVVLLAVIIGVTVVG
       : ::.:.....::::...:..: :.. :.:::.:: ..::. : . :...:.:::..:  
NP_919 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV-VLVAIIALIIGLSVGK
     230       240       250       260       270        280        




297 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:51:28 2016 done: Fri Nov  4 10:51:29 2016
 Total Scan time:  6.020 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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