Result of FASTA (omim) for pF1KB8207
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8207, 292 aa
  1>>>pF1KB8207 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.4607+/-0.000632; mu= -21.6651+/- 0.037
 mean_var=689.7793+/-154.269, 0's: 0 Z-trim(115.9): 1454  B-trim: 0 in 0/58
 Lambda= 0.048834
 statistics sampled from 24561 (26598) to 24561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.312), width:  16
 Scan time:  6.510

The best scores are:                                      opt bits E(85289)
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1994 155.9 8.4e-38
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1216 101.1 2.7e-21
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1183 98.8 1.4e-20
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1134 95.7 2.1e-19
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1134 95.7 2.1e-19
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1134 95.7 2.1e-19
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1134 95.7 2.1e-19
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1133 95.6 2.1e-19
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1133 95.6 2.1e-19
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1133 95.6 2.1e-19
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1133 95.6 2.2e-19
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1133 95.6 2.2e-19
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1133 95.6 2.2e-19
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1133 95.6 2.3e-19
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1133 95.6 2.3e-19
NP_001157882 (OMIM: 123831,616342) cyclin-dependen ( 260) 1108 93.4 4.8e-19
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1097 92.7   9e-19
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1097 92.7   9e-19
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1097 92.7   9e-19
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1099 93.1 1.1e-18
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1099 93.1 1.1e-18
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1099 93.2 1.1e-18
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1099 93.2 1.2e-18
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1099 93.2 1.2e-18
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1037 88.7 2.1e-17
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1037 88.7 2.2e-17
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1037 88.7 2.2e-17
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1037 88.8 2.2e-17
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1037 88.8 2.2e-17
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384)  974 84.2 4.3e-16
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384)  974 84.2 4.3e-16
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400)  974 84.2 4.4e-16
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412)  974 84.3 4.5e-16
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429)  974 84.3 4.6e-16
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435)  974 84.3 4.6e-16
NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340)  946 82.2 1.6e-15


>>NP_004926 (OMIM: 123831,616342) cyclin-dependent-like   (292 aa)
 initn: 1994 init1: 1994 opt: 1994  Z-score: 799.6  bits: 155.9 E(85289): 8.4e-38
Smith-Waterman score: 1994; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)

               10        20        30        40        50        60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
              190       200       210       220       230       240

              250       260       270       280       290  
pF1KB8 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
              250       260       270       280       290  

>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho  (305 aa)
 initn: 585 init1: 585 opt: 1216  Z-score: 503.2  bits: 101.1 E(85289): 2.7e-21
Smith-Waterman score: 1216; 61.4% identity (85.3% similar) in 293 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
       :. ..:.:::::::::.:.::::::: ..::::..::: . :::::.:.::: :::::::
NP_001 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
               10        20        30        40        50        60

               70        80        90       100        110         
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHS
        ::::: ::.:...:: ::::: .::::::.::  :.  : ...::.:::::.:..::::
NP_001 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY
       . :.::::::::::::. : .::::::::::::.:.: :. :::::::: :..:.:.:.:
NP_001 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-P
       .:..:.:: ::::::...  . ::::..  ::: ::::.::::.:. ::..:.:::::  
NP_001 TTAVDIWSIGCIFAEMVTR-KALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
              190        200       210       220       230         

      240       250       260       270       280       290        
pF1KB8 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP      
       .: . .  .: ..::.:.  :::::..::. .: :::.:. :: :::::.  :       
NP_001 FPKW-TRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQY
     240        250       260       270       280       290        

NP_001 VLQRFRH
      300     

>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso  (298 aa)
 initn: 1004 init1: 524 opt: 1183  Z-score: 490.7  bits: 98.8 E(85289): 1.4e-20
Smith-Waterman score: 1183; 59.9% identity (82.0% similar) in 294 aa overlap (1-292:1-292)

               10        20        30        40        50        60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
       :....:.:::::::::.:.::.:. : :.::::..::: . :::::.:.::: :::::.:
NP_001 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
               10        20        30        40        50        60

               70        80        90       100        110         
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHS
        :::.: ::.:...:: :::::  :::::..:.      :  ..::.:::::.::.::::
NP_001 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY
       . :::::::::::::: .: .::::::::::::.::: :. :::::::: :..:.: : :
NP_001 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-
       ::..:.:: ::::::...  : ::::..  ::: :::: :::: :  ::..:..::::: 
NP_001 STAVDIWSLGCIFAEMVTR-RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS
              190        200       210       220       230         

      240       250       260       270       280       290        
pF1KB8 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP      
       .: . :  .. .::: :.  ::.::...:. .: .::::. :: ::.:.:   :      
NP_001 FPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
     240        250       260       270       280       290        

>>NP_002586 (OMIM: 603440) cyclin-dependent kinase 17 is  (523 aa)
 initn: 1050 init1: 779 opt: 1134  Z-score: 469.4  bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     :. : ::::.:::::.::.:.... :...:
NP_002 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
NP_002 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
NP_002 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
       280       290       300       310       320       330       

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        ..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
NP_002 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
       340       350       360       370       380        390      

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       .:. ::::::::..: ::....  ..: :  : :     :.: .:.:.. : .:. ..:.
NP_002 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
        400       410       420       430        440       450     

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:.:::::..: :: .. :                                     
NP_002 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     

>>XP_016874894 (OMIM: 603440) PREDICTED: cyclin-dependen  (523 aa)
 initn: 1050 init1: 779 opt: 1134  Z-score: 469.4  bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     :. : ::::.:::::.::.:.... :...:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
XP_016 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
       280       290       300       310       320       330       

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        ..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
XP_016 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
       340       350       360       370       380        390      

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       .:. ::::::::..: ::....  ..: :  : :     :.: .:.:.. : .:. ..:.
XP_016 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
        400       410       420       430        440       450     

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:.:::::..: :: .. :                                     
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     

>>NP_001163935 (OMIM: 603440) cyclin-dependent kinase 17  (523 aa)
 initn: 1050 init1: 779 opt: 1134  Z-score: 469.4  bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     :. : ::::.:::::.::.:.... :...:
NP_001 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
NP_001 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
NP_001 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
       280       290       300       310       320       330       

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        ..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
NP_001 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
       340       350       360       370       380        390      

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       .:. ::::::::..: ::....  ..: :  : :     :.: .:.:.. : .:. ..:.
NP_001 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
        400       410       420       430        440       450     

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:.:::::..: :: .. :                                     
NP_001 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFV
         460       470       480       490       500       510     

>>XP_016874895 (OMIM: 603440) PREDICTED: cyclin-dependen  (523 aa)
 initn: 1050 init1: 779 opt: 1134  Z-score: 469.4  bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     :. : ::::.:::::.::.:.... :...:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
XP_016 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
       280       290       300       310       320       330       

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        ..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
XP_016 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
       340       350       360       370       380        390      

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       .:. ::::::::..: ::....  ..: :  : :     :.: .:.:.. : .:. ..:.
XP_016 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
        400       410       420       430        440       450     

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:.:::::..: :: .. :                                     
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     

>>NP_006192 (OMIM: 311550) cyclin-dependent kinase 16 is  (496 aa)
 initn: 1044 init1: 774 opt: 1133  Z-score: 469.3  bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     .. : ::.:.:::::.::.:.:.. : ..:
NP_006 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
             140       150       160       170       180       190 

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
NP_006 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
             200        210       220       230       240       250

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
NP_006 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
              260       270       280       290       300       310

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        .::.. :: :::::::::::.:.:.  :::.::::..:::: :.:. :::::::. :..
NP_006 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
              320       330       340       350        360         

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       ::. :::.::::::: ::.. .  ..: :  : : :  .:.. .:.:.. : ::: .::.
NP_006 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
     370       380       390       400        410       420        

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:::::.:..::.:                                          
NP_006 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
      430       440       450       460       470       480        

>>XP_016885060 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 1044 init1: 774 opt: 1133  Z-score: 469.3  bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     .. : ::.:.:::::.::.:.:.. : ..:
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
             140       150       160       170       180       190 

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
             200        210       220       230       240       250

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
XP_016 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
              260       270       280       290       300       310

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        .::.. :: :::::::::::.:.:.  :::.::::..:::: :.:. :::::::. :..
XP_016 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
              320       330       340       350        360         

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       ::. :::.::::::: ::.. .  ..: :  : : :  .:.. .:.:.. : ::: .::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
     370       380       390       400        410       420        

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:::::.:..::.:                                          
XP_016 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
      430       440       450       460       470       480        

>>XP_016885062 (OMIM: 311550) PREDICTED: cyclin-dependen  (496 aa)
 initn: 1044 init1: 774 opt: 1133  Z-score: 469.3  bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)

                                             10        20        30
pF1KB8                               MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
                                     .. : ::.:.:::::.::.:.:.. : ..:
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
             140       150       160       170       180       190 

               40        50        60        70        80        90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
       :::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
             200        210       220       230       240       250

              100       110       120       130       140       150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
       .:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
XP_016 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
              260       270       280       290       300       310

              160       170       180       190       200       210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
        .::.. :: :::::::::::.:.:.  :::.::::..:::: :.:. :::::::. :..
XP_016 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
              320       330       340       350        360         

              220       230         240       250       260        
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
       ::. :::.::::::: ::.. .  ..: :  : : :  .:.. .:.:.. : ::: .::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
     370       380       390       400        410       420        

      270       280       290                                      
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP                                    
        .  .:::::.:..::.:                                          
XP_016 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
      430       440       450       460       470       480        




292 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:33:41 2016 done: Fri Nov  4 10:33:42 2016
 Total Scan time:  6.510 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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