Result of FASTA (omim) for pF1KB8173
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8173, 358 aa
  1>>>pF1KB8173 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9707+/-0.000287; mu= 11.5231+/- 0.018
 mean_var=158.2609+/-31.296, 0's: 0 Z-trim(122.9): 117  B-trim: 0 in 0/58
 Lambda= 0.101950
 statistics sampled from 41752 (41880) to 41752 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.491), width:  16
 Scan time:  9.720

The best scores are:                                      opt bits E(85289)
XP_016877694 (OMIM: 601740) PREDICTED: homeobox pr ( 306) 1007 159.1 1.2e-38
NP_758527 (OMIM: 601740) homeobox protein Meis2 is ( 306) 1007 159.1 1.2e-38
NP_002390 (OMIM: 601740) homeobox protein Meis2 is ( 381) 1007 159.2 1.3e-38
XP_006720588 (OMIM: 601740) PREDICTED: homeobox pr ( 393) 1007 159.3 1.4e-38
NP_733774 (OMIM: 601740) homeobox protein Meis2 is ( 394) 1007 159.3 1.4e-38
XP_016859635 (OMIM: 601739) PREDICTED: homeobox pr ( 246)  994 157.1 3.7e-38
XP_005264382 (OMIM: 601739) PREDICTED: homeobox pr ( 325)  994 157.3 4.5e-38
NP_002389 (OMIM: 601739) homeobox protein Meis1 [H ( 390)  994 157.3 5.2e-38
XP_005264380 (OMIM: 601739) PREDICTED: homeobox pr ( 406)  994 157.4 5.3e-38
NP_733776 (OMIM: 601740) homeobox protein Meis2 is ( 470)  953 151.4 3.8e-36
NP_001207411 (OMIM: 601740) homeobox protein Meis2 ( 470)  953 151.4 3.8e-36
XP_016859634 (OMIM: 601739) PREDICTED: homeobox pr ( 321)  936 148.7 1.7e-35
XP_016859633 (OMIM: 601739) PREDICTED: homeobox pr ( 321)  936 148.7 1.7e-35
XP_005264381 (OMIM: 601739) PREDICTED: homeobox pr ( 400)  936 148.8 1.9e-35
XP_005264379 (OMIM: 601739) PREDICTED: homeobox pr ( 465)  936 148.9 2.2e-35
XP_005264378 (OMIM: 601739) PREDICTED: homeobox pr ( 481)  936 148.9 2.2e-35
XP_006720592 (OMIM: 601740) PREDICTED: homeobox pr ( 255)  913 145.2 1.5e-34
XP_006720590 (OMIM: 601740) PREDICTED: homeobox pr ( 331)  913 145.4 1.8e-34
XP_011519893 (OMIM: 601740) PREDICTED: homeobox pr ( 331)  913 145.4 1.8e-34
NP_758526 (OMIM: 601740) homeobox protein Meis2 is ( 388)  913 145.4   2e-34
XP_006720589 (OMIM: 601740) PREDICTED: homeobox pr ( 389)  913 145.4   2e-34
XP_006720587 (OMIM: 601740) PREDICTED: homeobox pr ( 400)  913 145.4   2e-34
NP_733777 (OMIM: 601740) homeobox protein Meis2 is ( 401)  913 145.4   2e-34
XP_006720586 (OMIM: 601740) PREDICTED: homeobox pr ( 476)  913 145.5 2.3e-34
NP_733775 (OMIM: 601740) homeobox protein Meis2 is ( 477)  913 145.5 2.3e-34
XP_016859632 (OMIM: 601739) PREDICTED: homeobox pr ( 352)  849 136.0 1.3e-31
XP_016859631 (OMIM: 601739) PREDICTED: homeobox pr ( 417)  849 136.0 1.4e-31
XP_016859630 (OMIM: 601739) PREDICTED: homeobox pr ( 433)  849 136.1 1.5e-31
XP_006718957 (OMIM: 613066) PREDICTED: homeobox pr ( 339)  373 65.9 1.5e-10
XP_016873600 (OMIM: 613066) PREDICTED: homeobox pr ( 339)  373 65.9 1.5e-10
XP_011541249 (OMIM: 613066) PREDICTED: homeobox pr ( 339)  373 65.9 1.5e-10
XP_005271700 (OMIM: 613066) PREDICTED: homeobox pr ( 443)  373 66.1 1.8e-10
XP_011541247 (OMIM: 613066) PREDICTED: homeobox pr ( 472)  373 66.1 1.8e-10
NP_071345 (OMIM: 613066) homeobox protein PKNOX2 [ ( 472)  373 66.1 1.8e-10
XP_005271699 (OMIM: 613066) PREDICTED: homeobox pr ( 472)  373 66.1 1.8e-10
XP_011541246 (OMIM: 613066) PREDICTED: homeobox pr ( 472)  373 66.1 1.8e-10
XP_016873599 (OMIM: 613066) PREDICTED: homeobox pr ( 472)  373 66.1 1.8e-10
NP_001273187 (OMIM: 602100) homeobox protein PKNOX ( 319)  368 65.2 2.3e-10
NP_001307623 (OMIM: 602100) homeobox protein PKNOX ( 435)  368 65.3 2.9e-10
NP_004562 (OMIM: 602100) homeobox protein PKNOX1 i ( 436)  368 65.3 2.9e-10
NP_620410 (OMIM: 300411) homeobox protein TGIF2LX  ( 241)  268 50.4 5.1e-06
NP_631960 (OMIM: 400025) homeobox protein TGIF2LY  ( 185)  262 49.4 7.8e-06
NP_001186444 (OMIM: 607294) homeobox protein TGIF2 ( 237)  256 48.6 1.7e-05
NP_001186443 (OMIM: 607294) homeobox protein TGIF2 ( 237)  256 48.6 1.7e-05
NP_068581 (OMIM: 607294) homeobox protein TGIF2 [H ( 237)  256 48.6 1.7e-05
NP_001186442 (OMIM: 607294) homeobox protein TGIF2 ( 237)  256 48.6 1.7e-05
NP_733796 (OMIM: 142946,602630) homeobox protein T ( 401)  254 48.5 3.1e-05
NP_001265611 (OMIM: 142946,602630) homeobox protei ( 275)  249 47.6 3.9e-05
NP_775300 (OMIM: 142946,602630) homeobox protein T ( 272)  246 47.2 5.2e-05
XP_016881447 (OMIM: 142946,602630) PREDICTED: home ( 272)  246 47.2 5.2e-05


>>XP_016877694 (OMIM: 601740) PREDICTED: homeobox protei  (306 aa)
 initn: 1077 init1: 659 opt: 1007  Z-score: 815.1  bits: 159.1 E(85289): 1.2e-38
Smith-Waterman score: 1377; 67.8% identity (84.1% similar) in 314 aa overlap (69-358:1-306)

       40        50        60        70        80        90        
pF1KB8 RPPQPLPPGLDSDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGD
                                     .::::::::::::.::. . :      :::
XP_016                               MALVFEKCELATCTPREPGVA------GGD
                                             10        20          

      100       110       120       130       140                  
pF1KB8 VCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK---------
       ::::::::::::.::::::.:.:::::::::::::::::::::::::::::         
XP_016 VCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFC
           30        40        50        60        70        80    

             150       160       170       180        190          
pF1KB8 --------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LG
               :::::::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  :
XP_016 HRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAG
           90       100       110       120       130        140   

     200       210       220       230       240       250         
pF1KB8 TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNI
       :::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::
XP_016 TPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNI
           150       160       170        180       190       200  

     260       270       280       290       300       310         
pF1KB8 MRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGA
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::. .:::
XP_016 MRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGA
            210       220       230       240       250       260  

      320       330        340          350        
pF1KB8 AFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       :.::::::.:... . : :...:: :   ..::.....:.:::.
XP_016 AYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
            270       280       290       300      

>>NP_758527 (OMIM: 601740) homeobox protein Meis2 isofor  (306 aa)
 initn: 1077 init1: 659 opt: 1007  Z-score: 815.1  bits: 159.1 E(85289): 1.2e-38
Smith-Waterman score: 1377; 67.8% identity (84.1% similar) in 314 aa overlap (69-358:1-306)

       40        50        60        70        80        90        
pF1KB8 RPPQPLPPGLDSDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGD
                                     .::::::::::::.::. . :      :::
NP_758                               MALVFEKCELATCTPREPGVA------GGD
                                             10        20          

      100       110       120       130       140                  
pF1KB8 VCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK---------
       ::::::::::::.::::::.:.:::::::::::::::::::::::::::::         
NP_758 VCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFC
           30        40        50        60        70        80    

             150       160       170       180        190          
pF1KB8 --------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LG
               :::::::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  :
NP_758 HRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAG
           90       100       110       120       130        140   

     200       210       220       230       240       250         
pF1KB8 TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNI
       :::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::
NP_758 TPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNI
           150       160       170        180       190       200  

     260       270       280       290       300       310         
pF1KB8 MRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGA
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::. .:::
NP_758 MRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGA
            210       220       230       240       250       260  

      320       330        340          350        
pF1KB8 AFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       :.::::::.:... . : :...:: :   ..::.....:.:::.
NP_758 AYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
            270       280       290       300      

>>NP_002390 (OMIM: 601740) homeobox protein Meis2 isofor  (381 aa)
 initn: 1231 init1: 659 opt: 1007  Z-score: 813.9  bits: 159.2 E(85289): 1.3e-38
Smith-Waterman score: 1522; 63.8% identity (79.1% similar) in 378 aa overlap (9-358:14-381)

                    10        20        30        40         50    
pF1KB8      MARRYDELPHYPGIVDGPAALASFPETVPAVPGPYGPHRP-PQPLPPGLDS---D
                    :: :  .     :   :     .   :: : : :. .: .. :   :
NP_002 MDGVGVPASMYGDPHAPRPIPPVHHLNHGPPL--HATQHYGAHAPHPNVMPASMGSAVND
               10        20        30          40        50        

              60        70        80        90       100       110 
pF1KB8 GLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAA
       .:::.:: ::::::::::::::::::::::.::. . :      :::::::::::::::.
NP_002 ALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVA------GGDVCSSDSFNEDIAV
       60        70        80        90             100       110  

             120       130       140                        150    
pF1KB8 FAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK-----------------GKMPI
       ::::::.:.:::::::::::::::::::::::::::::                 :::::
NP_002 FAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPI
            120       130       140       150       160       170  

          160       170       180        190        200       210  
pF1KB8 DLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGTPGPSSGGLASQS
       ::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  ::::::::: ::::
NP_002 DLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGTPGPSSGGHASQS
            180       190       200        210       220       230 

            220       230       240       250       260       270  
pF1KB8 GDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAWLFQHLSHPY
       :::::.::::::.:::::..: .:.: :....:.::::::::::::::::::::::.:::
NP_002 GDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPY
             240       250        260       270       280       290

            280       290       300       310        320       330 
pF1KB8 PSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSPEGQPIGGYT
       :::::::::::::::::::::::::::::::::::::::::. .::::.::::::.:...
NP_002 PSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFV
              300       310       320       330       340       350

              340          350        
pF1KB8 -ETQPHVAVRPPG---SVGMSLNLEGEWHYL
        . : :...:: :   ..::.....:.:::.
NP_002 LDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
              360       370       380 

>>XP_006720588 (OMIM: 601740) PREDICTED: homeobox protei  (393 aa)
 initn: 1280 init1: 659 opt: 1007  Z-score: 813.8  bits: 159.3 E(85289): 1.4e-38
Smith-Waterman score: 1570; 63.2% identity (78.9% similar) in 399 aa overlap (5-358:4-393)

               10           20        30                      40   
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
           ::::::: :. ::   ::.. . :..   .:       ::       :: : : :.
XP_006  MFLYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
                10         20        30        40        50        

             50           60        70        80        90         
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
        .: .. :   :.:::.:: ::::::::::::::::::::::.::. . ::      :::
XP_006 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
       60        70        80        90       100             110  

     100       110       120       130       140                   
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
       :::::::::::.::::::.:.:::::::::::::::::::::::::::::          
XP_006 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
            120       130       140       150       160       170  

            150       160       170       180        190        200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
              :::::::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  ::
XP_006 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
            180       190       200       210        220       230 

              210       220       230       240       250       260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
       ::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
XP_006 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
             240       250       260        270       280       290

              270       280       290       300       310          
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
       ::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
XP_006 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
              300       310       320       330       340       350

     320       330        340          350        
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       .::::::.:... . : :...:: :   ..::.....:.:::.
XP_006 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
              360       370       380       390   

>>NP_733774 (OMIM: 601740) homeobox protein Meis2 isofor  (394 aa)
 initn: 1300 init1: 659 opt: 1007  Z-score: 813.7  bits: 159.3 E(85289): 1.4e-38
Smith-Waterman score: 1590; 63.3% identity (79.2% similar) in 403 aa overlap (1-358:1-394)

               10           20        30                      40   
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
       ::.:::::::: :. ::   ::.. . :..   .:       ::       :: : : :.
NP_733 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
               10         20        30        40        50         

             50           60        70        80        90         
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
        .: .. :   :.:::.:: ::::::::::::::::::::::.::. . ::      :::
NP_733 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
      60        70        80        90       100       110         

     100       110       120       130       140                   
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
       :::::::::::.::::::.:.:::::::::::::::::::::::::::::          
NP_733 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
           120       130       140       150       160       170   

            150       160       170       180        190        200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
              :::::::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  ::
NP_733 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
           180       190       200       210        220       230  

              210       220       230       240       250       260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
       ::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
NP_733 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
            240       250       260        270       280       290 

              270       280       290       300       310          
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
       ::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
NP_733 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
             300       310       320       330       340       350 

     320       330        340          350        
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       .::::::.:... . : :...:: :   ..::.....:.:::.
NP_733 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
             360       370       380       390    

>>XP_016859635 (OMIM: 601739) PREDICTED: homeobox protei  (246 aa)
 initn: 901 init1: 506 opt: 994  Z-score: 806.0  bits: 157.1 E(85289): 3.7e-38
Smith-Waterman score: 1048; 65.1% identity (82.7% similar) in 249 aa overlap (133-358:1-246)

            110       120       130       140                      
pF1KB8 DSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK-------------
                                     :::::::::::::::::             
XP_016                               MIQAIQVLRFHLLELEKVHELCDNFCHRYI
                                             10        20        30

         150       160       170       180       190        200    
pF1KB8 ----GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIRDHEDSGSVHLG-TPGPS
           :::::::::.::.:: . : ::   :  .: :: . : :::.:..:.. : :::::
XP_016 SCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNRDHDDTASTRSGGTPGPS
               40        50        60          70        80        

          210       220       230       240       250       260    
pF1KB8 SGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAWL
       ::: .:.::::::.::::::.::::::.: .:.: :....:.::::::::::::::::::
XP_016 SGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHKKRGIFPKVATNIMRAWL
       90       100       110        120       130       140       

          270       280       290       300       310        320   
pF1KB8 FQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSPE
       ::::.::::::::::::::::::::::::::::::::::::::::::::. .::. ..:.
XP_016 FQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPD
       150       160       170       180       190       200       

           330        340          350        
pF1KB8 GQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       :::.::.. . : :...: ::   ..::....::.:::.
XP_016 GQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
       210       220       230       240      

>>XP_005264382 (OMIM: 601739) PREDICTED: homeobox protei  (325 aa)
 initn: 1127 init1: 506 opt: 994  Z-score: 804.5  bits: 157.3 E(85289): 4.5e-38
Smith-Waterman score: 1410; 65.5% identity (83.2% similar) in 333 aa overlap (50-358:2-325)

      20        30        40        50        60         70        
pF1KB8 ALASFPETVPAVPGPYGPHRPPQPLPPGLDSDGLKREKDEIYG-HPLFPLLALVFEKCEL
                                     ..::. . ..  : :::::::::.::::::
XP_005                              MAQGLRLQGSRRKGRHPLFPLLALIFEKCEL
                                            10        20        30 

       80        90       100       110       120       130        
pF1KB8 ATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQ
       :::.::. . ::      ::::::.:::::::.::::.:.:.::::::::::::::::::
XP_005 ATCTPREPGVAG------GDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQ
              40              50        60        70        80     

      140                        150       160       170       180 
pF1KB8 VLRFHLLELEK-----------------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPD
       :::::::::::                 :::::::::.::.:: . : ::   :  .: :
XP_005 VLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTD
          90       100       110       120       130       140     

             190        200       210       220       230       240
pF1KB8 QNNMWIRDHEDSGSVHLG-TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLD
       : . : :::.:..:.. : :::::::: .:.::::::.::::::.::::::.: .:.: :
XP_005 QPS-WNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPD
           150       160       170       180       190        200  

              250       260       270       280       290       300
pF1KB8 QERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINAR
       ....:.::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 KDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR
            210       220       230       240       250       260  

              310        320       330        340          350     
pF1KB8 RRIVQPMIDQSNRT-GQGAAFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEW
       :::::::::::::. .::. ..:.:::.::.. . : :...: ::   ..::....::.:
XP_005 RRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQW
            270       280       290       300       310       320  

          
pF1KB8 HYL
       ::.
XP_005 HYM
          

>>NP_002389 (OMIM: 601739) homeobox protein Meis1 [Homo   (390 aa)
 initn: 1192 init1: 506 opt: 994  Z-score: 803.5  bits: 157.3 E(85289): 5.2e-38
Smith-Waterman score: 1535; 61.2% identity (79.2% similar) in 400 aa overlap (1-358:1-390)

               10           20            30            40         
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETV----PAVPGPYGP----HRPPQP-----L
       ::.:::.:::: :. ::   :... . :...    :.    .::    :. :.      .
NP_002 MAQRYDDLPHYGGM-DGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAM
               10         20        30        40        50         

           50           60        70        80        90       100 
pF1KB8 PPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCS
        :.. :   :.:::.:: ::::::::::::.:::::::::.::. . ::      :::::
NP_002 APSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAG------GDVCS
      60        70        80        90       100             110   

             110       120       130       140                     
pF1KB8 SDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK------------
       :.:::::::.::::.:.:.:::::::::::::::::::::::::::::            
NP_002 SESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRY
           120       130       140       150       160       170   

          150       160       170       180       190        200   
pF1KB8 -----GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIRDHEDSGSVHLG-TPGP
            :::::::::.::.:: . : ::   :  .: :: . : :::.:..:.. : ::::
NP_002 ISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNRDHDDTASTRSGGTPGP
           180       190       200        210        220       230 

           210       220       230       240       250       260   
pF1KB8 SSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAW
       :::: .:.::::::.::::::.::::::.: .:.: :....:.:::::::::::::::::
NP_002 SSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHKKRGIFPKVATNIMRAW
             240       250       260        270       280       290

           270       280       290       300       310        320  
pF1KB8 LFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSP
       :::::.::::::::::::::::::::::::::::::::::::::::::::. .::. ..:
NP_002 LFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNP
              300       310       320       330       340       350

            330        340          350        
pF1KB8 EGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       .:::.::.. . : :...: ::   ..::....::.:::.
NP_002 DGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
              360       370       380       390

>>XP_005264380 (OMIM: 601739) PREDICTED: homeobox protei  (406 aa)
 initn: 1172 init1: 506 opt: 994  Z-score: 803.2  bits: 157.4 E(85289): 5.3e-38
Smith-Waterman score: 1515; 61.1% identity (79.0% similar) in 396 aa overlap (5-358:21-406)

                               10           20            30       
pF1KB8                 MARRYDELPHYPGIVDG---PAALASFPETV----PAVPGPYGP
                           ::.:::: :. ::   :... . :...    :.    .::
XP_005 MAQRRKMESCAFAFEFALNLYDDLPHYGGM-DGVGIPSTMYGDPHAARSMQPVHHLNHGP
               10        20        30         40        50         

            40             50           60        70        80     
pF1KB8 ----HRPPQP-----LPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRD
           :. :.      . :.. :   :.:::.:: ::::::::::::.:::::::::.::.
XP_005 PLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPRE
      60        70        80        90       100       110         

          90       100       110       120       130       140     
pF1KB8 GAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLL
        . ::      ::::::.:::::::.::::.:.:.:::::::::::::::::::::::::
XP_005 PGVAG------GDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLL
     120             130       140       150       160       170   

                          150       160       170       180        
pF1KB8 ELEK-----------------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIR
       ::::                 :::::::::.::.:: . : ::   :  .: :: . : :
XP_005 ELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNR
           180       190       200       210       220         230 

      190        200       210       220       230       240       
pF1KB8 DHEDSGSVHLG-TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNK
       ::.:..:.. : :::::::: .:.::::::.::::::.::::::.: .:.: :....:.:
XP_005 DHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHK
             240       250       260       270        280       290

       250       260       270       280       290       300       
pF1KB8 KRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPM
       :::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_005 KRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPM
              300       310       320       330       340       350

       310        320       330        340          350        
pF1KB8 IDQSNRT-GQGAAFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
       ::::::. .::. ..:.:::.::.. . : :...: ::   ..::....::.:::.
XP_005 IDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
              360       370       380       390       400      

>>NP_733776 (OMIM: 601740) homeobox protein Meis2 isofor  (470 aa)
 initn: 1203 init1: 659 opt: 953  Z-score: 769.8  bits: 151.4 E(85289): 3.8e-36
Smith-Waterman score: 1536; 64.3% identity (78.7% similar) in 389 aa overlap (1-347:1-380)

               10           20        30                      40   
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
       ::.:::::::: :. ::   ::.. . :..   .:       ::       :: : : :.
NP_733 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
               10         20        30        40        50         

             50           60        70        80        90         
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
        .: .. :   :.:::.:: ::::::::::::::::::::::.::. . ::      :::
NP_733 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
      60        70        80        90       100       110         

     100       110       120       130       140                   
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
       :::::::::::.::::::.:.:::::::::::::::::::::::::::::          
NP_733 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
           120       130       140       150       160       170   

            150       160       170       180        190        200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
              :::::::::..:::. . : :.  .:  .: :.: . : :::.:. :.:  ::
NP_733 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
           180       190       200       210        220       230  

              210       220       230       240       250       260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
       ::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
NP_733 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
            240       250       260        270       280       290 

              270       280       290       300       310          
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
       ::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
NP_733 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
             300       310       320       330       340       350 

     320       330        340       350                            
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPGSVGMSLNLEGEWHYL                    
       .::::::.:... . : :...:: :  .:                               
NP_733 YSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQ
             360       370       380       390       400       410 




358 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:14:35 2016 done: Fri Nov  4 10:14:36 2016
 Total Scan time:  9.720 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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