Result of FASTA (omim) for pF1KB8142
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8142, 394 aa
  1>>>pF1KB8142 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0740+/-0.000346; mu= 19.7052+/- 0.022
 mean_var=83.5295+/-17.161, 0's: 0 Z-trim(115.7): 75  B-trim: 12 in 1/52
 Lambda= 0.140331
 statistics sampled from 26187 (26263) to 26187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.308), width:  16
 Scan time:  8.090

The best scores are:                                      opt bits E(85289)
XP_011526595 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_011526592 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_011526596 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_011526594 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
NP_078828 (OMIM: 615334) ceramide synthase 4 [Homo ( 394) 2698 555.9 6.1e-158
XP_016882794 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_011526593 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_016882793 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_016882792 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
XP_011526597 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 2698 555.9 6.1e-158
NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 1288 270.4 5.1e-72
NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 1288 270.4 5.1e-72
XP_011507754 (OMIM: 606920) PREDICTED: ceramide sy ( 380) 1288 270.4 5.1e-72
XP_011507753 (OMIM: 606920) PREDICTED: ceramide sy ( 400) 1288 270.4 5.3e-72
NP_001277271 (OMIM: 615023,615276) ceramide syntha ( 383) 1174 247.3 4.6e-65
NP_001277272 (OMIM: 615023,615276) ceramide syntha ( 383) 1174 247.3 4.6e-65
NP_849164 (OMIM: 615023,615276) ceramide synthase  ( 383) 1174 247.3 4.6e-65
XP_016877493 (OMIM: 615023,615276) PREDICTED: cera ( 383) 1174 247.3 4.6e-65
XP_016877492 (OMIM: 615023,615276) PREDICTED: cera ( 383) 1174 247.3 4.6e-65
NP_001277270 (OMIM: 615023,615276) ceramide syntha ( 394) 1174 247.3 4.7e-65
XP_011519660 (OMIM: 615023,615276) PREDICTED: cera ( 394) 1174 247.3 4.7e-65
XP_011519657 (OMIM: 615023,615276) PREDICTED: cera ( 394) 1174 247.3 4.7e-65
XP_011519659 (OMIM: 615023,615276) PREDICTED: cera ( 394) 1174 247.3 4.7e-65
XP_016877491 (OMIM: 615023,615276) PREDICTED: cera ( 394) 1174 247.3 4.7e-65
NP_671723 (OMIM: 615335) ceramide synthase 5 isofo ( 392) 1108 234.0 4.9e-61
NP_982288 (OMIM: 615336) ceramide synthase 6 isofo ( 384) 1081 228.5 2.1e-59
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392) 1073 226.9 6.6e-59
XP_005269277 (OMIM: 615335) PREDICTED: ceramide sy ( 409) 1065 225.3 2.1e-58
NP_001243055 (OMIM: 615336) ceramide synthase 6 is ( 392) 1055 223.2 8.3e-58
NP_001318000 (OMIM: 615335) ceramide synthase 5 is ( 381) 1052 222.6 1.2e-57
NP_001268660 (OMIM: 615335) ceramide synthase 5 is ( 334)  929 197.7 3.5e-50
XP_016875693 (OMIM: 615335) PREDICTED: ceramide sy ( 290)  909 193.6 5.3e-49
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334)  894 190.6 4.8e-48
NP_001317998 (OMIM: 615335) ceramide synthase 5 is ( 323)  873 186.3 8.9e-47
NP_001318001 (OMIM: 615335) ceramide synthase 5 is ( 248)  716 154.4 2.7e-37
NP_001318002 (OMIM: 615335) ceramide synthase 5 is ( 237)  660 143.1 6.9e-34
XP_016875694 (OMIM: 615335) PREDICTED: ceramide sy ( 237)  660 143.1 6.9e-34
XP_016859238 (OMIM: 615336) PREDICTED: ceramide sy ( 251)  611 133.2 6.9e-31
XP_005246497 (OMIM: 615336) PREDICTED: ceramide sy ( 200)  475 105.5 1.1e-22
NP_067090 (OMIM: 606919,616230) ceramide synthase  ( 350)  268 63.9   7e-10
NP_937850 (OMIM: 606919,616230) ceramide synthase  ( 337)  263 62.8 1.4e-09
NP_001277194 (OMIM: 606919,616230) ceramide syntha ( 239)  243 58.6 1.8e-08
XP_011513307 (OMIM: 608485) PREDICTED: translocati ( 333)  206 51.3 4.1e-06
NP_036420 (OMIM: 608485) translocating chain-assoc ( 370)  206 51.3 4.4e-06
XP_016868755 (OMIM: 605190) PREDICTED: translocati ( 278)  188 47.6 4.5e-05
XP_016868756 (OMIM: 605190) PREDICTED: translocati ( 278)  188 47.6 4.5e-05
NP_001304734 (OMIM: 605190) translocating chain-as ( 288)  184 46.8 8.1e-05
NP_001304733 (OMIM: 605190) translocating chain-as ( 343)  184 46.8 9.1e-05
NP_055109 (OMIM: 605190) translocating chain-assoc ( 374)  184 46.9 9.7e-05


>>XP_011526595 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_011526592 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_011526596 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_011526594 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>NP_078828 (OMIM: 615334) ceramide synthase 4 [Homo sap  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_078 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_078 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
NP_078 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_016882794 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_016 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_011526593 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_016882793 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_016 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_016882792 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_016 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    

>>XP_011526597 (OMIM: 615334) PREDICTED: ceramide syntha  (394 aa)
 initn: 2698 init1: 2698 opt: 2698  Z-score: 2956.5  bits: 555.9 E(85289): 6.1e-158
Smith-Waterman score: 2698; 99.2% identity (99.7% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB8 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTIYYESISNRGPFF
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEVAAAQEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
              310       320       330       340       350       360

              370       380       390    
pF1KB8 QLKNGAAGGPRPAPTDGPQSRVAGRLTNRHTTAT
       ::::::::::::::::::.:::::::::::::::
XP_011 QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
              370       380       390    




394 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:57:39 2016 done: Fri Nov  4 09:57:40 2016
 Total Scan time:  8.090 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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