Result of FASTA (omim) for pF1KB8133
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8133, 566 aa
  1>>>pF1KB8133 566 - 566 aa - 566 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8847+/-0.000395; mu= 16.0902+/- 0.025
 mean_var=110.9702+/-23.677, 0's: 0 Z-trim(113.6): 90  B-trim: 78 in 1/55
 Lambda= 0.121751
 statistics sampled from 22996 (23085) to 22996 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.271), width:  16
 Scan time:  8.320

The best scores are:                                      opt bits E(85289)
NP_061871 (OMIM: 609072) F-box/WD repeat-containin ( 566) 3849 687.7 2.6e-197
XP_005266146 (OMIM: 609072) PREDICTED: F-box/WD re ( 576) 3029 543.7  6e-154
XP_016870301 (OMIM: 609072) PREDICTED: F-box/WD re ( 548) 2366 427.2 6.6e-119
XP_011517091 (OMIM: 609072) PREDICTED: F-box/WD re ( 558) 1546 283.2 1.5e-75


>>NP_061871 (OMIM: 609072) F-box/WD repeat-containing pr  (566 aa)
 initn: 3849 init1: 3849 opt: 3849  Z-score: 3663.3  bits: 687.7 E(85289): 2.6e-197
Smith-Waterman score: 3849; 99.8% identity (100.0% similar) in 566 aa overlap (1-566:1-566)

               10        20        30        40        50        60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 RDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_061 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
              490       500       510       520       530       540

              550       560      
pF1KB8 PRTMRVLQAPRPRPRTFFSWLASQRR
       ::::::::::::::::::::::::::
NP_061 PRTMRVLQAPRPRPRTFFSWLASQRR
              550       560      

>>XP_005266146 (OMIM: 609072) PREDICTED: F-box/WD repeat  (576 aa)
 initn: 3029 init1: 3029 opt: 3029  Z-score: 2884.8  bits: 543.7 E(85289): 6e-154
Smith-Waterman score: 3819; 98.1% identity (98.3% similar) in 576 aa overlap (1-566:1-576)

               10        20        30        40        50        60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVK---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_005 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAIT
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 -------IWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB8 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB8 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB8 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB8 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
              370       380       390       400       410       420

              420       430       440       450       460       470
pF1KB8 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
              430       440       450       460       470       480

              480       490       500       510       520       530
pF1KB8 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTAS
       :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_005 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTAS
              490       500       510       520       530       540

              540       550       560      
pF1KB8 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
       ::::::::::::::::::::::::::::::::::::
XP_005 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
              550       560       570      

>>XP_016870301 (OMIM: 609072) PREDICTED: F-box/WD repeat  (548 aa)
 initn: 3709 init1: 2350 opt: 2366  Z-score: 2255.7  bits: 427.2 E(85289): 6.6e-119
Smith-Waterman score: 3677; 96.6% identity (96.8% similar) in 566 aa overlap (1-566:1-548)

               10        20        30        40        50        60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_016 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKS------------
              310       320       330       340                    

              370       380       390       400       410       420
pF1KB8 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ------IKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
            350       360       370       380       390       400  

              430       440       450       460       470       480
pF1KB8 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
            410       420       430       440       450       460  

              490       500       510       520       530       540
pF1KB8 RDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
            470       480       490       500       510       520  

              550       560      
pF1KB8 PRTMRVLQAPRPRPRTFFSWLASQRR
       ::::::::::::::::::::::::::
XP_016 PRTMRVLQAPRPRPRTFFSWLASQRR
            530       540        

>>XP_011517091 (OMIM: 609072) PREDICTED: F-box/WD repeat  (558 aa)
 initn: 2889 init1: 1530 opt: 1546  Z-score: 1477.2  bits: 283.2 E(85289): 1.5e-75
Smith-Waterman score: 3647; 95.0% identity (95.1% similar) in 576 aa overlap (1-566:1-558)

               10        20        30        40        50        60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVK---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAIT
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB8 -------IWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB8 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB8 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB8 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKS--
              310       320       330       340       350          

              360       370       380       390       400       410
pF1KB8 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------------IKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
                      360       370       380       390       400  

              420       430       440       450       460       470
pF1KB8 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
            410       420       430       440       450       460  

              480       490       500       510       520       530
pF1KB8 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTAS
       :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_011 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTAS
            470       480       490       500       510       520  

              540       550       560      
pF1KB8 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
       ::::::::::::::::::::::::::::::::::::
XP_011 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
            530       540       550        




566 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:51:06 2016 done: Fri Nov  4 09:51:07 2016
 Total Scan time:  8.320 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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