Result of FASTA (omim) for pF1KB7730
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7730, 480 aa
  1>>>pF1KB7730 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.4072+/-0.000344; mu= -4.4418+/- 0.021
 mean_var=287.3304+/-60.261, 0's: 0 Z-trim(123.8): 45  B-trim: 0 in 0/57
 Lambda= 0.075663
 statistics sampled from 44102 (44147) to 44102 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.518), width:  16
 Scan time:  9.860

The best scores are:                                      opt bits E(85289)
NP_116027 (OMIM: 137295,614038,614172,614286) endo ( 480) 3401 384.3  4e-106
NP_001139133 (OMIM: 137295,614038,614172,614286) e ( 480) 3401 384.3  4e-106
NP_001139134 (OMIM: 137295,614038,614172,614286) e ( 466) 2446 280.1 9.4e-75
NP_001002295 (OMIM: 131320,146255) trans-acting T- ( 444) 1362 161.7 3.8e-39
XP_005252500 (OMIM: 131320,146255) PREDICTED: tran ( 444) 1362 161.7 3.8e-39
XP_005252499 (OMIM: 131320,146255) PREDICTED: tran ( 444) 1362 161.7 3.8e-39
NP_002042 (OMIM: 131320,146255) trans-acting T-cel ( 443) 1347 160.1 1.2e-38
XP_016868801 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
XP_006716311 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
XP_011542120 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
XP_005272443 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
XP_005272442 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
XP_011542119 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
NP_001295022 (OMIM: 187500,600576,607941,614429,61 ( 443)  855 106.4 1.7e-22
NP_002043 (OMIM: 187500,600576,607941,614429,61443 ( 442)  846 105.4 3.4e-22
NP_002040 (OMIM: 190685,300367,300835,305371,31405 ( 413)  830 103.6 1.1e-21
XP_011542199 (OMIM: 190685,300367,300835,305371,31 ( 418)  810 101.4   5e-21
XP_011542200 (OMIM: 190685,300367,300835,305371,31 ( 335)  804 100.7 6.6e-21
NP_005248 (OMIM: 187500,217095,600001,601656,61447 ( 595)  768 97.0 1.6e-19
NP_001295023 (OMIM: 187500,600576,607941,614429,61 ( 236)  730 92.5 1.3e-18
XP_006723762 (OMIM: 611496) PREDICTED: transcripti ( 397)  722 91.8 3.7e-18
NP_536721 (OMIM: 611496) transcription factor GATA ( 397)  722 91.8 3.7e-18


>>NP_116027 (OMIM: 137295,614038,614172,614286) endothel  (480 aa)
 initn: 3401 init1: 3401 opt: 3401  Z-score: 2026.2  bits: 384.3 E(85289): 4e-106
Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)

               10        20        30        40        50        60
pF1KB7 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
              430       440       450       460       470       480

>>NP_001139133 (OMIM: 137295,614038,614172,614286) endot  (480 aa)
 initn: 3401 init1: 3401 opt: 3401  Z-score: 2026.2  bits: 384.3 E(85289): 4e-106
Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)

               10        20        30        40        50        60
pF1KB7 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
              430       440       450       460       470       480

>>NP_001139134 (OMIM: 137295,614038,614172,614286) endot  (466 aa)
 initn: 2573 init1: 2417 opt: 2446  Z-score: 1463.0  bits: 280.1 E(85289): 9.4e-75
Smith-Waterman score: 3258; 97.1% identity (97.1% similar) in 480 aa overlap (1-480:1-466)

               10        20        30        40        50        60
pF1KB7 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
       :::::::::::::::::::::::::::::::::::::::              :::::::
NP_001 TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL--------------TTTTTLW
              310       320       330                     340      

              370       380       390       400       410       420
pF1KB7 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
        350       360       370       380       390       400      

              430       440       450       460       470       480
pF1KB7 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
        410       420       430       440       450       460      

>>NP_001002295 (OMIM: 131320,146255) trans-acting T-cell  (444 aa)
 initn: 1622 init1: 930 opt: 1362  Z-score: 823.8  bits: 161.7 E(85289): 3.8e-39
Smith-Waterman score: 1938; 62.6% identity (78.0% similar) in 486 aa overlap (1-480:1-444)

               10          20        30        40        50        
pF1KB7 MEVAPEQPRWMAH--PAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGN-
       :::. .::::..:  :::::.::::.:::::.:.::. ::   :.::::.:: .:.::: 
NP_001 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFN-IDGQGNH
               10        20        30        40        50          

          60        70        80        90       100       110     
pF1KB7 --PYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH-N
         :::.: ..: ..  : :.:    :.:.::: :::. .:::::::::  :    ::  .
NP_001 VPPYYGNSVRATVQ-RYPPTHH---GSQVCRPPLLHG-SLPWLDGGKALGS----HHTAS
      60        70         80           90        100           110

          120       130       140       150       160       170    
pF1KB7 PWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFP
       ::..:::::: .:    :.:: :::::: :...: .:.            :.. ::: ::
NP_001 PWNLSPFSKTSIHH---GSPG-PLSVYPPASSSSLSGG------------HASPHLFTFP
              120           130       140                   150    

          180       190       200       210       220       230    
pF1KB7 PTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLA
       :::::.:::::: .   .:.:.   ::: : ..:. .:::: : .:::.::.       :
NP_001 PTPPKDVSPDPSLS---TPGSA---GSA-RQDEKECLKYQVPLPDSMKLESSHSRGSMTA
          160          170           180       190       200       

          240       250       260       270       280       290    
pF1KB7 TMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRE
         :.. .::::: ::: :::    .:::::: :...:::  ..:  :.: :::: .::::
NP_001 LGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRE
       210       220           230       240       250       260   

          300       310       320       330       340       350    
pF1KB7 CVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQT
       :::::::.::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_001 CVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQT
           270       280       290       300       310       320   

          360       370       380       390       400       410    
pF1KB7 TTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECF
       :::::::::::::::::::::::::::.:::::::::::::::::::.:::: ::  . .
NP_001 TTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSL
           330       340       350       360       370       380   

          420       430       440       450       460       470    
pF1KB7 EELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSS
       :.. :     .: :. :::. ::. ..:. :::::.:.: ::::.:: ::::::  ::::
NP_001 EDFPK-----NSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSS
                390       400       410       420       430        

          480
pF1KB7 MVTAMG
       ::::::
NP_001 MVTAMG
      440    

>>XP_005252500 (OMIM: 131320,146255) PREDICTED: trans-ac  (444 aa)
 initn: 1622 init1: 930 opt: 1362  Z-score: 823.8  bits: 161.7 E(85289): 3.8e-39
Smith-Waterman score: 1938; 62.6% identity (78.0% similar) in 486 aa overlap (1-480:1-444)

               10          20        30        40        50        
pF1KB7 MEVAPEQPRWMAH--PAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGN-
       :::. .::::..:  :::::.::::.:::::.:.::. ::   :.::::.:: .:.::: 
XP_005 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFN-IDGQGNH
               10        20        30        40        50          

          60        70        80        90       100       110     
pF1KB7 --PYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH-N
         :::.: ..: ..  : :.:    :.:.::: :::. .:::::::::  :    ::  .
XP_005 VPPYYGNSVRATVQ-RYPPTHH---GSQVCRPPLLHG-SLPWLDGGKALGS----HHTAS
      60        70         80           90        100           110

          120       130       140       150       160       170    
pF1KB7 PWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFP
       ::..:::::: .:    :.:: :::::: :...: .:.            :.. ::: ::
XP_005 PWNLSPFSKTSIHH---GSPG-PLSVYPPASSSSLSGG------------HASPHLFTFP
              120           130       140                   150    

          180       190       200       210       220       230    
pF1KB7 PTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLA
       :::::.:::::: .   .:.:.   ::: : ..:. .:::: : .:::.::.       :
XP_005 PTPPKDVSPDPSLS---TPGSA---GSA-RQDEKECLKYQVPLPDSMKLESSHSRGSMTA
          160          170           180       190       200       

          240       250       260       270       280       290    
pF1KB7 TMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRE
         :.. .::::: ::: :::    .:::::: :...:::  ..:  :.: :::: .::::
XP_005 LGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRE
       210       220           230       240       250       260   

          300       310       320       330       340       350    
pF1KB7 CVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQT
       :::::::.::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 CVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQT
           270       280       290       300       310       320   

          360       370       380       390       400       410    
pF1KB7 TTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECF
       :::::::::::::::::::::::::::.:::::::::::::::::::.:::: ::  . .
XP_005 TTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSL
           330       340       350       360       370       380   

          420       430       440       450       460       470    
pF1KB7 EELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSS
       :.. :     .: :. :::. ::. ..:. :::::.:.: ::::.:: ::::::  ::::
XP_005 EDFPK-----NSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSS
                390       400       410       420       430        

          480
pF1KB7 MVTAMG
       ::::::
XP_005 MVTAMG
      440    

>>XP_005252499 (OMIM: 131320,146255) PREDICTED: trans-ac  (444 aa)
 initn: 1622 init1: 930 opt: 1362  Z-score: 823.8  bits: 161.7 E(85289): 3.8e-39
Smith-Waterman score: 1938; 62.6% identity (78.0% similar) in 486 aa overlap (1-480:1-444)

               10          20        30        40        50        
pF1KB7 MEVAPEQPRWMAH--PAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGN-
       :::. .::::..:  :::::.::::.:::::.:.::. ::   :.::::.:: .:.::: 
XP_005 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFN-IDGQGNH
               10        20        30        40        50          

          60        70        80        90       100       110     
pF1KB7 --PYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH-N
         :::.: ..: ..  : :.:    :.:.::: :::. .:::::::::  :    ::  .
XP_005 VPPYYGNSVRATVQ-RYPPTHH---GSQVCRPPLLHG-SLPWLDGGKALGS----HHTAS
      60        70         80           90        100           110

          120       130       140       150       160       170    
pF1KB7 PWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFP
       ::..:::::: .:    :.:: :::::: :...: .:.            :.. ::: ::
XP_005 PWNLSPFSKTSIHH---GSPG-PLSVYPPASSSSLSGG------------HASPHLFTFP
              120           130       140                   150    

          180       190       200       210       220       230    
pF1KB7 PTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLA
       :::::.:::::: .   .:.:.   ::: : ..:. .:::: : .:::.::.       :
XP_005 PTPPKDVSPDPSLS---TPGSA---GSA-RQDEKECLKYQVPLPDSMKLESSHSRGSMTA
          160          170           180       190       200       

          240       250       260       270       280       290    
pF1KB7 TMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRE
         :.. .::::: ::: :::    .:::::: :...:::  ..:  :.: :::: .::::
XP_005 LGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRE
       210       220           230       240       250       260   

          300       310       320       330       340       350    
pF1KB7 CVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQT
       :::::::.::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 CVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQT
           270       280       290       300       310       320   

          360       370       380       390       400       410    
pF1KB7 TTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECF
       :::::::::::::::::::::::::::.:::::::::::::::::::.:::: ::  . .
XP_005 TTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSL
           330       340       350       360       370       380   

          420       430       440       450       460       470    
pF1KB7 EELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSS
       :.. :     .: :. :::. ::. ..:. :::::.:.: ::::.:: ::::::  ::::
XP_005 EDFPK-----NSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSS
                390       400       410       420       430        

          480
pF1KB7 MVTAMG
       ::::::
XP_005 MVTAMG
      440    

>>NP_002042 (OMIM: 131320,146255) trans-acting T-cell-sp  (443 aa)
 initn: 1482 init1: 819 opt: 1347  Z-score: 815.0  bits: 160.1 E(85289): 1.2e-38
Smith-Waterman score: 1923; 62.6% identity (77.8% similar) in 486 aa overlap (1-480:1-443)

               10          20        30        40        50        
pF1KB7 MEVAPEQPRWMAH--PAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGN-
       :::. .::::..:  :::::.::::.:::::.:.::. ::   :.::::.:: .:.::: 
NP_002 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFN-IDGQGNH
               10        20        30        40        50          

          60        70        80        90       100       110     
pF1KB7 --PYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH-N
         :::.: ..: ..  : :.:    :.:.::: :::. .:::::::::  :    ::  .
NP_002 VPPYYGNSVRATVQ-RYPPTHH---GSQVCRPPLLHG-SLPWLDGGKALGS----HHTAS
      60        70         80           90        100           110

          120       130       140       150       160       170    
pF1KB7 PWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFP
       ::..:::::: .:    :.:: :::::: :...: .:.            :.. ::: ::
NP_002 PWNLSPFSKTSIHH---GSPG-PLSVYPPASSSSLSGG------------HASPHLFTFP
              120           130       140                   150    

          180       190       200       210       220       230    
pF1KB7 PTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLA
       :::::.:::::: .   .:.:.   ::: : ..:. .:::: : .:::.::.       :
NP_002 PTPPKDVSPDPSLS---TPGSA---GSA-RQDEKECLKYQVPLPDSMKLESSHSRGSMTA
          160          170           180       190       200       

          240       250       260       270       280       290    
pF1KB7 TMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRE
         :.. .::::: ::: :::    .:::::: :...:::  ..:  :.: :::: : :::
NP_002 LGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARS-STGRE
       210       220           230       240       250        260  

          300       310       320       330       340       350    
pF1KB7 CVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQT
       :::::::.::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_002 CVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQT
            270       280       290       300       310       320  

          360       370       380       390       400       410    
pF1KB7 TTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECF
       :::::::::::::::::::::::::::.:::::::::::::::::::.:::: ::  . .
NP_002 TTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSL
            330       340       350       360       370       380  

          420       430       440       450       460       470    
pF1KB7 EELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSS
       :.. :     .: :. :::. ::. ..:. :::::.:.: ::::.:: ::::::  ::::
NP_002 EDFPK-----NSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSS
                 390       400       410       420       430       

          480
pF1KB7 MVTAMG
       ::::::
NP_002 MVTAMG
       440   

>>XP_016868801 (OMIM: 187500,600576,607941,614429,614430  (443 aa)
 initn: 802 init1: 704 opt: 855  Z-score: 524.7  bits: 106.4 E(85289): 1.7e-22
Smith-Waterman score: 855; 43.4% identity (64.0% similar) in 403 aa overlap (93-472:15-399)

             70        80        90       100       110       120  
pF1KB7 PAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFS
                                     ::  .  :: .:.  .:.   .:  : :  
XP_016                 MYQSLAMAANHGPPPG-AYEAGGPGAFMHGAGAASSPVYV-P--
                               10         20        30         40  

            130            140       150       160           170   
pF1KB7 KTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGSSVASLT----PTAAHSGSHLFGF
        ::  ::.. :      ::  :.  ::.:::.::..:...  :    :  ...:.   ..
XP_016 -TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAY
                50        60        70        80        90         

           180          190       200       210       220       230
pF1KB7 PPTPPKEVSPD---PSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLR
        : ::  :::    :.:::. . :...:..  : . .. :    ..:  . . . :   :
XP_016 TP-PP--VSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGL--AGREQYG---R
     100          110       120       130       140         150    

              240       250          260         270       280     
pF1KB7 PGLATMGTQPATHHPIPTYPSYVPAAAHD---YSSGLFH--PGGFLGGPASSFTPKQRSK
        :.:   ..:   .   .  :.. ::: .   ..: ..:  ::   ..::.   :.  . 
XP_016 AGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPG--RANPAARH-PNLVDM
             160       170       180       190         200         

         290       300       310       320       330       340     
pF1KB7 ARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRA
         . ::::::::::: .::::::::::::::::::::::::: :::::::.:::::.::.
XP_016 FDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRV
      210       220       230       240       250       260        

         350       360       370       380       390       400     
pF1KB7 GTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSK
       :  ::::::::::::::::.:.:::::::::.:::.: :::.:.:::::::.:: .: .:
XP_016 GLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNK
      270       280       290       300       310       320        

         410       420       430         440        450       460  
pF1KB7 KSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAPVGHLPPFS-HSGHILPTPTPIHPS
       ..  .:    :     .  ::  : :. ..  .: :.   : .: : ::   . .     
XP_016 SKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHS-SSVSQTFSV
      330       340       350       360       370        380       

             470         480                                    
pF1KB7 SSLSFGH-P--HPSSMVTAMG                                    
       :..: :: :  ::                                            
XP_016 SAMS-GHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA
       390        400       410       420       430       440   

>>XP_006716311 (OMIM: 187500,600576,607941,614429,614430  (443 aa)
 initn: 802 init1: 704 opt: 855  Z-score: 524.7  bits: 106.4 E(85289): 1.7e-22
Smith-Waterman score: 855; 43.4% identity (64.0% similar) in 403 aa overlap (93-472:15-399)

             70        80        90       100       110       120  
pF1KB7 PAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFS
                                     ::  .  :: .:.  .:.   .:  : :  
XP_006                 MYQSLAMAANHGPPPG-AYEAGGPGAFMHGAGAASSPVYV-P--
                               10         20        30         40  

            130            140       150       160           170   
pF1KB7 KTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGSSVASLT----PTAAHSGSHLFGF
        ::  ::.. :      ::  :.  ::.:::.::..:...  :    :  ...:.   ..
XP_006 -TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAY
                50        60        70        80        90         

           180          190       200       210       220       230
pF1KB7 PPTPPKEVSPD---PSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLR
        : ::  :::    :.:::. . :...:..  : . .. :    ..:  . . . :   :
XP_006 TP-PP--VSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGL--AGREQYG---R
     100          110       120       130       140         150    

              240       250          260         270       280     
pF1KB7 PGLATMGTQPATHHPIPTYPSYVPAAAHD---YSSGLFH--PGGFLGGPASSFTPKQRSK
        :.:   ..:   .   .  :.. ::: .   ..: ..:  ::   ..::.   :.  . 
XP_006 AGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPG--RANPAARH-PNLVDM
             160       170       180       190         200         

         290       300       310       320       330       340     
pF1KB7 ARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRA
         . ::::::::::: .::::::::::::::::::::::::: :::::::.:::::.::.
XP_006 FDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRV
      210       220       230       240       250       260        

         350       360       370       380       390       400     
pF1KB7 GTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSK
       :  ::::::::::::::::.:.:::::::::.:::.: :::.:.:::::::.:: .: .:
XP_006 GLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNK
      270       280       290       300       310       320        

         410       420       430         440        450       460  
pF1KB7 KSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAPVGHLPPFS-HSGHILPTPTPIHPS
       ..  .:    :     .  ::  : :. ..  .: :.   : .: : ::   . .     
XP_006 SKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHS-SSVSQTFSV
      330       340       350       360       370        380       

             470         480                                    
pF1KB7 SSLSFGH-P--HPSSMVTAMG                                    
       :..: :: :  ::                                            
XP_006 SAMS-GHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA
       390        400       410       420       430       440   

>>XP_011542120 (OMIM: 187500,600576,607941,614429,614430  (443 aa)
 initn: 802 init1: 704 opt: 855  Z-score: 524.7  bits: 106.4 E(85289): 1.7e-22
Smith-Waterman score: 855; 43.4% identity (64.0% similar) in 403 aa overlap (93-472:15-399)

             70        80        90       100       110       120  
pF1KB7 PAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFS
                                     ::  .  :: .:.  .:.   .:  : :  
XP_011                 MYQSLAMAANHGPPPG-AYEAGGPGAFMHGAGAASSPVYV-P--
                               10         20        30         40  

            130            140       150       160           170   
pF1KB7 KTPLHPSAAGG-----PGGPLSVYPGAGGGSGGGSGSSVASLT----PTAAHSGSHLFGF
        ::  ::.. :      ::  :.  ::.:::.::..:...  :    :  ...:.   ..
XP_011 -TPRVPSSVLGLSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAY
                50        60        70        80        90         

           180          190       200       210       220       230
pF1KB7 PPTPPKEVSPD---PSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLR
        : ::  :::    :.:::. . :...:..  : . .. :    ..:  . . . :   :
XP_011 TP-PP--VSPRFSFPGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGL--AGREQYG---R
     100          110       120       130       140         150    

              240       250          260         270       280     
pF1KB7 PGLATMGTQPATHHPIPTYPSYVPAAAHD---YSSGLFH--PGGFLGGPASSFTPKQRSK
        :.:   ..:   .   .  :.. ::: .   ..: ..:  ::   ..::.   :.  . 
XP_011 AGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPG--RANPAARH-PNLVDM
             160       170       180       190         200         

         290       300       310       320       330       340     
pF1KB7 ARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRA
         . ::::::::::: .::::::::::::::::::::::::: :::::::.:::::.::.
XP_011 FDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRV
      210       220       230       240       250       260        

         350       360       370       380       390       400     
pF1KB7 GTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSK
       :  ::::::::::::::::.:.:::::::::.:::.: :::.:.:::::::.:: .: .:
XP_011 GLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNK
      270       280       290       300       310       320        

         410       420       430         440        450       460  
pF1KB7 KSKKGAECFEELSKCMQEKSSPFSAAALAG--HMAPVGHLPPFS-HSGHILPTPTPIHPS
       ..  .:    :     .  ::  : :. ..  .: :.   : .: : ::   . .     
XP_011 SKTPAAPSGSESLPPASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHS-SSVSQTFSV
      330       340       350       360       370        380       

             470         480                                    
pF1KB7 SSLSFGH-P--HPSSMVTAMG                                    
       :..: :: :  ::                                            
XP_011 SAMS-GHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA
       390        400       410       420       430       440   




480 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:17:12 2016 done: Fri Nov  4 09:17:14 2016
 Total Scan time:  9.860 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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