Result of FASTA (omim) for pF1KB7543
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7543, 182 aa
  1>>>pF1KB7543 182 - 182 aa - 182 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5816+/-0.000315; mu= 12.6690+/- 0.020
 mean_var=83.7922+/-16.735, 0's: 0 Z-trim(116.7): 17  B-trim: 65 in 1/53
 Lambda= 0.140111
 statistics sampled from 27983 (28000) to 27983 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.328), width:  16
 Scan time:  5.810

The best scores are:                                      opt bits E(85289)
NP_001746 (OMIM: 121360) core-binding factor subun ( 182) 1240 259.7 1.9e-69
NP_074036 (OMIM: 121360) core-binding factor subun ( 187) 1150 241.5 5.9e-64
XP_016879302 (OMIM: 121360) PREDICTED: core-bindin ( 143)  647 139.7 1.9e-33
XP_005256269 (OMIM: 121360) PREDICTED: core-bindin ( 148)  647 139.7   2e-33
XP_016879301 (OMIM: 121360) PREDICTED: core-bindin ( 143)  593 128.8 3.7e-30
XP_006721384 (OMIM: 121360) PREDICTED: core-bindin ( 148)  503 110.6 1.1e-24


>>NP_001746 (OMIM: 121360) core-binding factor subunit b  (182 aa)
 initn: 1240 init1: 1240 opt: 1240  Z-score: 1367.7  bits: 259.7 E(85289): 1.9e-69
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
              130       140       150       160       170       180

         
pF1KB7 RP
       ::
NP_001 RP
         

>>NP_074036 (OMIM: 121360) core-binding factor subunit b  (187 aa)
 initn: 1175 init1: 1150 opt: 1150  Z-score: 1269.3  bits: 241.5 E(85289): 5.9e-64
Smith-Waterman score: 1150; 98.2% identity (99.4% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_074 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_074 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
       :::::::::::::::::::::::::::::::::::::::::::::.: .:          
NP_074 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
              130       140       150       160       170       180

              
pF1KB7 RP     
              
NP_074 GDDLKLR
              

>>XP_016879302 (OMIM: 121360) PREDICTED: core-binding fa  (143 aa)
 initn: 662 init1: 647 opt: 647  Z-score: 721.4  bits: 139.7 E(85289): 1.9e-33
Smith-Waterman score: 870; 78.6% identity (78.6% similar) in 182 aa overlap (1-182:1-143)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
       ::::::::::::::::::::::::::::::::::                          
XP_016 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGK--------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
                    :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------------QEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
                       100       110       120       130       140 

         
pF1KB7 RP
       ::
XP_016 RP
         

>>XP_005256269 (OMIM: 121360) PREDICTED: core-binding fa  (148 aa)
 initn: 869 init1: 647 opt: 647  Z-score: 721.2  bits: 139.7 E(85289): 2e-33
Smith-Waterman score: 780; 75.3% identity (76.5% similar) in 170 aa overlap (1-170:1-131)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
       ::::::::::::::::::::::::::::::::::                          
XP_005 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGK--------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
                    ::::::::::::::::::::::::::::::::.: .:          
XP_005 -------------QEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
                       100       110       120       130       140 

              
pF1KB7 RP     
              
XP_005 GDDLKLR
              

>>XP_016879301 (OMIM: 121360) PREDICTED: core-binding fa  (143 aa)
 initn: 593 init1: 593 opt: 593  Z-score: 662.4  bits: 128.8 E(85289): 3.7e-30
Smith-Waterman score: 892; 78.6% identity (78.6% similar) in 182 aa overlap (1-182:1-143)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEI-----
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
                                         ::::::::::::::::::::::::::
XP_016 ----------------------------------VYLKAPMILNGVCVIWKGWIDLQRLD
                                            60        70        80 

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
              90       100       110       120       130       140 

         
pF1KB7 RP
       ::
XP_016 RP
         

>>XP_006721384 (OMIM: 121360) PREDICTED: core-binding fa  (148 aa)
 initn: 896 init1: 503 opt: 503  Z-score: 563.9  bits: 110.6 E(85289): 1.1e-24
Smith-Waterman score: 802; 75.3% identity (76.5% similar) in 170 aa overlap (1-170:1-131)

               10        20        30        40        50        60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_006 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEI-----
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
                                         ::::::::::::::::::::::::::
XP_006 ----------------------------------VYLKAPMILNGVCVIWKGWIDLQRLD
                                            60        70        80 

              130       140       150       160       170       180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
       :::::::::::::::::::::::::::::::::::::::::::::.: .:          
XP_006 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
              90       100       110       120       130       140 

              
pF1KB7 RP     
              
XP_006 GDDLKLR
              




182 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:35:31 2016 done: Fri Nov  4 08:35:32 2016
 Total Scan time:  5.810 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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