Result of FASTA (omim) for pF1KB7447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7447, 272 aa
  1>>>pF1KB7447 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0614+/-0.000325; mu= 16.7104+/- 0.020
 mean_var=75.5878+/-14.710, 0's: 0 Z-trim(116.4): 64  B-trim: 18 in 1/50
 Lambda= 0.147519
 statistics sampled from 27488 (27556) to 27488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.323), width:  16
 Scan time:  6.900

The best scores are:                                      opt bits E(85289)
NP_060393 (OMIM: 613331) E3 ubiquitin-protein liga ( 272) 1891 411.5 8.5e-115
XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1644 358.9 5.9e-99
XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1644 358.9 5.9e-99
XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 289) 1642 358.5 7.9e-99
NP_001159845 (OMIM: 613331) E3 ubiquitin-protein l ( 289) 1642 358.5 7.9e-99
XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 545) 1482 324.7 2.3e-88
NP_001002266 (OMIM: 613335) E3 ubiquitin-protein l ( 291) 1190 262.3 7.3e-70
NP_659458 (OMIM: 613335) E3 ubiquitin-protein liga ( 291) 1190 262.3 7.3e-70
XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 1190 262.3 7.3e-70
XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 1190 262.3 7.3e-70
XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
NP_001269795 (OMIM: 613335) E3 ubiquitin-protein l ( 573) 1129 249.6 9.7e-66
NP_001005415 (OMIM: 613332) E3 ubiquitin-protein l ( 246)  300 72.9 6.7e-13
NP_057580 (OMIM: 613332) E3 ubiquitin-protein liga ( 246)  300 72.9 6.7e-13
XP_016882342 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 246)  300 72.9 6.7e-13
NP_848545 (OMIM: 613333) E3 ubiquitin-protein liga ( 253)  296 72.0 1.2e-12
XP_011526349 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256)  288 70.3   4e-12
XP_011526348 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256)  288 70.3   4e-12
NP_065865 (OMIM: 608208) E3 ubiquitin-protein liga ( 410)  268 66.2 1.1e-10
NP_001096032 (OMIM: 613338) E3 ubiquitin-protein l ( 402)  263 65.2 2.3e-10
XP_016864504 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 154)  258 63.7 2.3e-10
XP_011541431 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  261 64.6 2.3e-10
XP_011541433 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  261 64.6 2.3e-10
XP_011541432 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  261 64.6 2.3e-10
XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 460)  258 64.1 5.2e-10
XP_011512238 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 637)  258 64.3 6.7e-10
XP_011512236 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 791)  258 64.3 7.8e-10
NP_005876 (OMIM: 613297) E3 ubiquitin-protein liga ( 910)  258 64.4 8.7e-10
XP_006722826 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 176)  249 61.9 9.6e-10
NP_001005416 (OMIM: 613332) E3 ubiquitin-protein l ( 176)  249 61.9 9.6e-10
NP_001257589 (OMIM: 613297) E3 ubiquitin-protein l ( 862)  255 63.7 1.3e-09
NP_612405 (OMIM: 613336) E3 ubiquitin-protein liga ( 346)  247 61.7 2.1e-09
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752)  201 52.2 3.4e-06
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799)  201 52.2 3.5e-06
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799)  201 52.2 3.5e-06
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807)  201 52.2 3.6e-06
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808)  201 52.2 3.6e-06
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808)  201 52.2 3.6e-06
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824)  201 52.2 3.6e-06
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825)  201 52.2 3.6e-06
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825)  201 52.2 3.6e-06
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846)  201 52.2 3.7e-06
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862)  201 52.2 3.8e-06
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862)  201 52.2 3.8e-06
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863)  201 52.2 3.8e-06
XP_005257154 (OMIM: 613337) PREDICTED: probable E3 ( 863)  201 52.2 3.8e-06


>>NP_060393 (OMIM: 613331) E3 ubiquitin-protein ligase M  (272 aa)
 initn: 1891 init1: 1891 opt: 1891  Z-score: 2182.0  bits: 411.5 E(85289): 8.5e-115
Smith-Waterman score: 1891; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)

               10        20        30        40        50        60
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
              190       200       210       220       230       240

              250       260       270  
pF1KB7 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       ::::::::::::::::::::::::::::::::
NP_060 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
              250       260       270  

>>XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr  (285 aa)
 initn: 1640 init1: 1640 opt: 1644  Z-score: 1897.6  bits: 358.9 E(85289): 5.9e-99
Smith-Waterman score: 1644; 91.6% identity (96.2% similar) in 261 aa overlap (12-272:25-285)

                            10        20        30        40       
pF1KB7              MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP
                               :  :.... .    ...:. :. . .::::::::::
XP_016 MPLHQISVIPARETASNGRNSMGRNKEKNKEVENEKSPGRSASRSSNISKASSPTTGTAP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KB7 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KB7 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KB7 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
              190       200       210       220       230       240

       230       240       250       260       270  
pF1KB7 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
              250       260       270       280     

>>XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr  (285 aa)
 initn: 1640 init1: 1640 opt: 1644  Z-score: 1897.6  bits: 358.9 E(85289): 5.9e-99
Smith-Waterman score: 1644; 91.6% identity (96.2% similar) in 261 aa overlap (12-272:25-285)

                            10        20        30        40       
pF1KB7              MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP
                               :  :.... .    ...:. :. . .::::::::::
XP_016 MPLHQISVIPARETASNGRNSMGRNKEKNKEVENEKSPGRSASRSSNISKASSPTTGTAP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KB7 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KB7 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KB7 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
              190       200       210       220       230       240

       230       240       250       260       270  
pF1KB7 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
              250       260       270       280     

>>XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr  (289 aa)
 initn: 1640 init1: 1640 opt: 1642  Z-score: 1895.2  bits: 358.5 E(85289): 7.9e-99
Smith-Waterman score: 1642; 96.3% identity (98.8% similar) in 246 aa overlap (27-272:44-289)

                   10        20        30        40        50      
pF1KB7     MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
                                     ..:. :. . .:::::::::::::::::::
XP_016 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
            20        30        40        50        60        70   

         60        70        80        90       100       110      
pF1KB7 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
            80        90       100       110       120       130   

        120       130       140       150       160       170      
pF1KB7 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
           140       150       160       170       180       190   

        180       190       200       210       220       230      
pF1KB7 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
           200       210       220       230       240       250   

        240       250       260       270  
pF1KB7 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       ::::::::::::::::::::::::::::::::::::
XP_016 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
           260       270       280         

>>NP_001159845 (OMIM: 613331) E3 ubiquitin-protein ligas  (289 aa)
 initn: 1640 init1: 1640 opt: 1642  Z-score: 1895.2  bits: 358.5 E(85289): 7.9e-99
Smith-Waterman score: 1642; 96.3% identity (98.8% similar) in 246 aa overlap (27-272:44-289)

                   10        20        30        40        50      
pF1KB7     MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
                                     ..:. :. . .:::::::::::::::::::
NP_001 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
            20        30        40        50        60        70   

         60        70        80        90       100       110      
pF1KB7 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
            80        90       100       110       120       130   

        120       130       140       150       160       170      
pF1KB7 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
           140       150       160       170       180       190   

        180       190       200       210       220       230      
pF1KB7 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
           200       210       220       230       240       250   

        240       250       260       270  
pF1KB7 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       ::::::::::::::::::::::::::::::::::::
NP_001 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
           260       270       280         

>>XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr  (545 aa)
 initn: 1482 init1: 1482 opt: 1482  Z-score: 1707.5  bits: 324.7 E(85289): 2.3e-88
Smith-Waterman score: 1482; 99.1% identity (100.0% similar) in 212 aa overlap (61-272:334-545)

               40        50        60        70        80        90
pF1KB7 LSNLFLQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVH
                                     ..::::::::::::::::::::::::::::
XP_011 GSKDMNDAGLQVNNPVQKPPATYDDGSDNLEVCRICHCEGDEESPLITPCRCTGTLRFVH
           310       320       330       340       350       360   

              100       110       120       130       140       150
pF1KB7 QSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAIT
           370       380       390       400       410       420   

              160       170       180       190       200       210
pF1KB7 CVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWR
           430       440       450       460       470       480   

              220       230       240       250       260       270
pF1KB7 RLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVV
           490       500       510       520       530       540   

         
pF1KB7 SV
       ::
XP_011 SV
         

>--
 initn: 220 init1: 184 opt: 212  Z-score: 246.8  bits: 54.4 E(85289): 5.3e-07
Smith-Waterman score: 212; 37.4% identity (62.6% similar) in 115 aa overlap (27-139:44-156)

                   10        20        30        40        50      
pF1KB7     MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
                                     ..:. :. . .:::::::::::::::::::
XP_011 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
            20        30        40        50        60        70   

         60          70        80        90       100       110    
pF1KB7 PSTQDICR--ICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFI
       ::::::::  : :  ..:     ::    .  :  ..:  .. :.    :     .:.  
XP_011 PSTQDICRSAILHDMSEESFEYCTPVMVLSPAR--KESGKKSVIQRPRRRRKASERYEHA
            80        90       100         110       120       130 

          120       130       140       150       160       170    
pF1KB7 METKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNG
        : ...  ..  .::... . :...                                   
XP_011 AEEQIRGRKNDFHLQISSPRWRELYTDSSDSSSTDESHWIQAKRRAQVKFRLSRRRRRNN
             140       150       160       170       180       190 

>>NP_001002266 (OMIM: 613335) E3 ubiquitin-protein ligas  (291 aa)
 initn: 1159 init1: 1159 opt: 1190  Z-score: 1375.3  bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)

                       10        20        30        40            
pF1KB7         MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
                                     .........:    .:.:: ...::    :
NP_001 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
               20        30        40        50            60      

      50        60        70        80        90       100         
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
        :: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
NP_001 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
         70        80        90       100       110       120      

     110       120       130       140       150       160         
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
       ::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
NP_001 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
        130       140       150       160       170       180      

     170       180       190       200       210       220         
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
       :. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
NP_001 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
        190       200       210       220       230       240      

     230         240       250       260       270  
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :  .::.   . : . : .  .   .:...     :    :.. :
NP_001 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
        250       260       270       280       290 

>>NP_659458 (OMIM: 613335) E3 ubiquitin-protein ligase M  (291 aa)
 initn: 1159 init1: 1159 opt: 1190  Z-score: 1375.3  bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)

                       10        20        30        40            
pF1KB7         MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
                                     .........:    .:.:: ...::    :
NP_659 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
               20        30        40        50            60      

      50        60        70        80        90       100         
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
        :: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
NP_659 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
         70        80        90       100       110       120      

     110       120       130       140       150       160         
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
       ::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
NP_659 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
        130       140       150       160       170       180      

     170       180       190       200       210       220         
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
       :. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
NP_659 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
        190       200       210       220       230       240      

     230         240       250       260       270  
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :  .::.   . : . : .  .   .:...     :    :.. :
NP_659 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
        250       260       270       280       290 

>>XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (291 aa)
 initn: 1159 init1: 1159 opt: 1190  Z-score: 1375.3  bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)

                       10        20        30        40            
pF1KB7         MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
                                     .........:    .:.:: ...::    :
XP_016 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
               20        30        40        50            60      

      50        60        70        80        90       100         
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
        :: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
XP_016 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
         70        80        90       100       110       120      

     110       120       130       140       150       160         
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
       ::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
XP_016 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
        130       140       150       160       170       180      

     170       180       190       200       210       220         
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
       :. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
XP_016 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
        190       200       210       220       230       240      

     230         240       250       260       270  
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :  .::.   . : . : .  .   .:...     :    :.. :
XP_016 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
        250       260       270       280       290 

>>XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (291 aa)
 initn: 1159 init1: 1159 opt: 1190  Z-score: 1375.3  bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)

                       10        20        30        40            
pF1KB7         MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
                                     .........:    .:.:: ...::    :
XP_011 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
               20        30        40        50            60      

      50        60        70        80        90       100         
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
        :: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
XP_011 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
         70        80        90       100       110       120      

     110       120       130       140       150       160         
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
       ::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
XP_011 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
        130       140       150       160       170       180      

     170       180       190       200       210       220         
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
       :. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
XP_011 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
        190       200       210       220       230       240      

     230         240       250       260       270  
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
       :  .::.   . : . : .  .   .:...     :    :.. :
XP_011 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
        250       260       270       280       290 




272 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:55:02 2016 done: Fri Nov  4 07:55:03 2016
 Total Scan time:  6.900 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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