Result of FASTA (omim) for pF1KB7407
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7407, 213 aa
  1>>>pF1KB7407 213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2136+/-0.000249; mu= 14.9676+/- 0.016
 mean_var=67.8547+/-13.754, 0's: 0 Z-trim(122.6): 21  B-trim: 915 in 2/59
 Lambda= 0.155698
 statistics sampled from 40931 (40968) to 40931 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.48), width:  16
 Scan time:  4.520

The best scores are:                                      opt bits E(85289)
NP_001396 (OMIM: 602756) ephrin-A2 precursor [Homo ( 213) 1527 350.7   1e-96
XP_016881939 (OMIM: 602756) PREDICTED: ephrin-A2 i ( 202) 1208 279.1 3.6e-75
XP_016881938 (OMIM: 602756) PREDICTED: ephrin-A2 i ( 298) 1206 278.7 6.8e-75
XP_006714628 (OMIM: 601535) PREDICTED: ephrin-A5 i ( 201)  710 167.2 1.7e-41
NP_001953 (OMIM: 601535) ephrin-A5 precursor [Homo ( 228)  676 159.6 3.8e-39
XP_011541552 (OMIM: 601535) PREDICTED: ephrin-A5 i ( 210)  590 140.2 2.3e-33
NP_004943 (OMIM: 601381) ephrin-A3 precursor [Homo ( 238)  561 133.8 2.3e-31
NP_004419 (OMIM: 191164) ephrin-A1 isoform a precu ( 205)  457 110.4 2.2e-24
XP_011541553 (OMIM: 601535) PREDICTED: ephrin-A5 i ( 148)  449 108.5   6e-24
XP_016864694 (OMIM: 601535) PREDICTED: ephrin-A5 i ( 148)  449 108.5   6e-24
NP_872626 (OMIM: 191164) ephrin-A1 isoform b precu ( 183)  438 106.1 3.9e-23
NP_005218 (OMIM: 601380) ephrin-A4 isoform a precu ( 201)  396 96.7 2.9e-20
NP_872632 (OMIM: 601380) ephrin-A4 isoform c precu ( 193)  389 95.1 8.4e-20
NP_872631 (OMIM: 601380) ephrin-A4 isoform b precu ( 207)  384 94.0 1.9e-19
NP_001397 (OMIM: 602297) ephrin-B3 precursor [Homo ( 340)  237 61.1 2.5e-09
NP_004420 (OMIM: 300035,304110) ephrin-B1 precurso ( 346)  197 52.1 1.3e-06
NP_004084 (OMIM: 600527) ephrin-B2 precursor [Homo ( 333)  177 47.6 2.8e-05
XP_016875895 (OMIM: 600527) PREDICTED: ephrin-B2 i ( 335)  177 47.6 2.9e-05


>>NP_001396 (OMIM: 602756) ephrin-A2 precursor [Homo sap  (213 aa)
 initn: 1527 init1: 1527 opt: 1527  Z-score: 1857.4  bits: 350.7 E(85289): 1e-96
Smith-Waterman score: 1527; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)

               10        20        30        40        50        60
pF1KB7 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
              130       140       150       160       170       180

              190       200       210   
pF1KB7 PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS
       :::::::::::::::::::::::::::::::::
NP_001 PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS
              190       200       210   

>>XP_016881939 (OMIM: 602756) PREDICTED: ephrin-A2 isofo  (202 aa)
 initn: 1222 init1: 1206 opt: 1208  Z-score: 1470.4  bits: 279.1 E(85289): 3.6e-75
Smith-Waterman score: 1208; 87.6% identity (89.1% similar) in 201 aa overlap (18-213:2-202)

               10        20        30        40             50     
pF1KB7 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRS----NP-RFHAGAGDD
                        :: :   :   ..::     :    :     .: :::::::::
XP_016                 MLPAPLGLRETGVGRARFGTRASGLVRLRIALEPGRFHAGAGDD
                               10        20        30        40    

          60        70        80        90       100       110     
pF1KB7 GGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECN
           50        60        70        80        90       100    

         120       130       140       150       160       170     
pF1KB7 RPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNE
          110       120       130       140       150       160    

         180       190       200       210   
pF1KB7 TLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS
       ::::::::::::::::::::::::::::::::::::::
XP_016 TLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS
          170       180       190       200  

>>XP_016881938 (OMIM: 602756) PREDICTED: ephrin-A2 isofo  (298 aa)
 initn: 1206 init1: 1206 opt: 1206  Z-score: 1465.5  bits: 278.7 E(85289): 6.8e-75
Smith-Waterman score: 1206; 100.0% identity (100.0% similar) in 167 aa overlap (47-213:132-298)

         20        30        40        50        60        70      
pF1KB7 PLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHY
                                     ::::::::::::::::::::::::::::::
XP_016 LGHRETGVGRARFGTRASGLVRLRIALEPGRFHAGAGDDGGGYTVEVSINDYLDIYCPHY
             110       120       130       140       150       160 

         80        90       100       110       120       130      
pF1KB7 GAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPF
             170       180       190       200       210       220 

        140       150       160       170       180       190      
pF1KB7 SLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGG
             230       240       250       260       270       280 

        200       210   
pF1KB7 CRLFLSTIPVLWTLLGS
       :::::::::::::::::
XP_016 CRLFLSTIPVLWTLLGS
             290        

>>XP_006714628 (OMIM: 601535) PREDICTED: ephrin-A5 isofo  (201 aa)
 initn: 620 init1: 528 opt: 710  Z-score: 865.9  bits: 167.2 E(85289): 1.7e-41
Smith-Waterman score: 710; 56.0% identity (78.8% similar) in 184 aa overlap (11-194:7-181)

               10        20        30        40        50        60
pF1KB7 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
                 : :..: :    :.. . ...: .:::::::: :::::.       : : 
XP_006     MLHVEMLTLVFLVLWMCVFSQ-DPGSKAVADRYAVYWNSSNPRFQR------GDYH
                   10        20         30        40               

               70        80        90       100       110       120
pF1KB7 VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
       ..: ::::::..::::   .:  .. :.::::::: .:...::: ..:::::::::: .:
XP_006 IDVCINDYLDVFCPHYEDSVPE-DKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSP
      50        60        70         80        90       100        

              130       140       150       160       170       180
pF1KB7 GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
       .::::::::::::::::::::::::.::.:::.. :.   : ::.:::.:::::.:..:.
XP_006 NGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNDTVHES
      110       120       130       140       150       160        

              190       200       210    
pF1KB7 PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS 
        ::   ..:. ..:                    
XP_006 AEPS-RGENAAQTPRIPSRLLAILLFLLAMLLTL
      170        180       190       200 

>>NP_001953 (OMIM: 601535) ephrin-A5 precursor [Homo sap  (228 aa)
 initn: 671 init1: 475 opt: 676  Z-score: 823.8  bits: 159.6 E(85289): 3.8e-39
Smith-Waterman score: 676; 58.1% identity (78.4% similar) in 167 aa overlap (11-177:7-165)

               10        20        30        40        50        60
pF1KB7 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
                 : :..: :    :.. . ...: .:::::::: :::::. :       : 
NP_001     MLHVEMLTLVFLVLWMCVFSQ-DPGSKAVADRYAVYWNSSNPRFQRG------DYH
                   10        20         30        40               

               70        80        90       100       110       120
pF1KB7 VEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAP
       ..: ::::::..::::   .:  .. :.::::::: .:...::: ..:::::::::: .:
NP_001 IDVCINDYLDVFCPHYEDSVPE-DKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSP
      50        60        70         80        90       100        

              130       140       150       160       170       180
pF1KB7 GGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEA
       .::::::::::::::::::::::::.::.:::.. :.   : ::.:::.:::::  .   
NP_001 NGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTI
      110       120       130       140       150       160        

              190       200       210                              
pF1KB7 PEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS                           
                                                                   
NP_001 GVHDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
      170       180       190       200       210       220        

>>XP_011541552 (OMIM: 601535) PREDICTED: ephrin-A5 isofo  (210 aa)
 initn: 579 init1: 475 opt: 590  Z-score: 719.9  bits: 140.2 E(85289): 2.3e-33
Smith-Waterman score: 590; 64.5% identity (84.3% similar) in 121 aa overlap (57-177:28-147)

         30        40        50        60        70        80      
pF1KB7 EDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAERM
                                     : : ..: ::::::..::::   .:  .. 
XP_011    MQTLEPACFRFSLHTNTNKQCTLGFQRGDYHIDVCINDYLDVFCPHYEDSVPE-DKT
                  10        20        30        40        50       

         90       100       110       120       130       140      
pF1KB7 EHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGH
       :.::::::: .:...::: ..:::::::::: .:.::::::::::::::::::::::::.
XP_011 ERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGR
         60        70        80        90       100       110      

        150       160       170       180       190       200      
pF1KB7 EYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGGCRLFLSTIPV
       ::.:::.. :.   : ::.:::.:::::  .                             
XP_011 EYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHE
        120       130       140       150       160       170      

        210                              
pF1KB7 LWTLLGS                           
                                         
XP_011 SAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
        180       190       200       210

>>NP_004943 (OMIM: 601381) ephrin-A3 precursor [Homo sap  (238 aa)
 initn: 593 init1: 266 opt: 561  Z-score: 684.0  bits: 133.8 E(85289): 2.3e-31
Smith-Waterman score: 561; 53.4% identity (71.3% similar) in 174 aa overlap (4-170:2-165)

               10        20        30        40        50        60
pF1KB7 MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYT
          :  ::: :::::.:.:  :.  :.  . : ..:.::::: :: ...        :::
NP_004   MAAAPLL-LLLLLVPVPLLPLL-AQGPGGALGNRHAVYWNSSNQHLRRE------GYT
                  10        20         30        40              50

               70               80        90       100       110   
pF1KB7 VEVSINDYLDIYCPHY-------GAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWE
       :.:..:::::::::::       ::   :.   :.::::::. .:. .:.  : ::::::
NP_004 VQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQ-GFKRWE
               60        70        80        90       100          

           120       130       140       150       160       170   
pF1KB7 CNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPT
       :::: :: .:.::::::: .. ::::.::. :::::::: :: . .   :::.::.:   
NP_004 CNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYIS-TPTHNLHWKCLRMKVFVCCA
     110       120       130       140        150       160        

           180       190       200       210                       
pF1KB7 NETLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS                    
                                                                   
NP_004 STSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGI
      170       180       190       200       210       220        

>>NP_004419 (OMIM: 191164) ephrin-A1 isoform a precursor  (205 aa)
 initn: 470 init1: 362 opt: 457  Z-score: 558.6  bits: 110.4 E(85289): 2.2e-24
Smith-Waterman score: 462; 42.7% identity (62.0% similar) in 192 aa overlap (32-211:16-195)

              10        20        30        40        50        60 
pF1KB7 APAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYTV
                                     : .::..:.:: :::.:.   ..:   ::.
NP_004                MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFR---NED---YTI
                              10        20        30               

              70        80        90       100       110       120 
pF1KB7 EVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPG
       .:..:::.:: ::::         ::.:.::.:. : .  :. ...   ::.::::.:  
NP_004 HVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKH
      40        50        60        70        80        90         

             130       140       150       160       170           
pF1KB7 GPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVR----------
       :: :.::::: ::::.:: ::. :: :::::    .  :: :::::: :           
NP_004 GPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDR-CLRLKVTVSGKITHSPQAH
     100       110       120       130        140       150        

               180       190       200       210           
pF1KB7 --PTNETLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS        
         : .. :  : .:     .: .  .. :::    :. ::.:          
NP_004 DNPQEKRL-AADDPEVRVLHSIGHSAAPRLF----PLAWTVLLLPLLLLQTP
      160        170       180           190       200     

>>XP_011541553 (OMIM: 601535) PREDICTED: ephrin-A5 isofo  (148 aa)
 initn: 449 init1: 449 opt: 449  Z-score: 551.0  bits: 108.5 E(85289): 6e-24
Smith-Waterman score: 449; 69.4% identity (88.2% similar) in 85 aa overlap (93-177:1-85)

             70        80        90       100       110       120  
pF1KB7 VSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGG
                                     ::: .:...::: ..:::::::::: .:.:
XP_011                               MVNFDGYSACDHTSKGFKRWECNRPHSPNG
                                             10        20        30

            130       140       150       160       170       180  
pF1KB7 PLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPE
       :::::::::::::::::::::::.::.:::.. :.   : ::.:::.:::::  .     
XP_011 PLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGV
               40        50        60        70        80        90

            190       200       210                              
pF1KB7 PIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS                           
                                                                 
XP_011 HDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
              100       110       120       130       140        

>>XP_016864694 (OMIM: 601535) PREDICTED: ephrin-A5 isofo  (148 aa)
 initn: 449 init1: 449 opt: 449  Z-score: 551.0  bits: 108.5 E(85289): 6e-24
Smith-Waterman score: 449; 69.4% identity (88.2% similar) in 85 aa overlap (93-177:1-85)

             70        80        90       100       110       120  
pF1KB7 VSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGG
                                     ::: .:...::: ..:::::::::: .:.:
XP_016                               MVNFDGYSACDHTSKGFKRWECNRPHSPNG
                                             10        20        30

            130       140       150       160       170       180  
pF1KB7 PLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPE
       :::::::::::::::::::::::.::.:::.. :.   : ::.:::.:::::  .     
XP_016 PLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGV
               40        50        60        70        80        90

            190       200       210                              
pF1KB7 PIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS                           
                                                                 
XP_016 HDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
              100       110       120       130       140        




213 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:29:50 2016 done: Fri Nov  4 07:29:50 2016
 Total Scan time:  4.520 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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