Result of FASTA (omim) for pF1KB7405
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7405, 485 aa
  1>>>pF1KB7405 485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2299+/-0.000352; mu= 19.3760+/- 0.022
 mean_var=81.7964+/-16.332, 0's: 0 Z-trim(115.2): 35  B-trim: 440 in 2/53
 Lambda= 0.141810
 statistics sampled from 25503 (25538) to 25503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.299), width:  16
 Scan time:  9.790

The best scores are:                                      opt bits E(85289)
NP_061183 (OMIM: 611146,613280) zinc transporter 1 ( 485) 3211 666.8 3.8e-191
XP_016857173 (OMIM: 611146,613280) PREDICTED: zinc ( 326) 1829 383.9 3.7e-106
XP_006711500 (OMIM: 611146,613280) PREDICTED: zinc ( 422) 1829 384.0 4.5e-106
NP_067017 (OMIM: 609521) zinc transporter 1 [Homo  ( 507)  547 121.8 4.7e-27
NP_001166284 (OMIM: 125853,611145) zinc transporte ( 320)  285 68.0 4.5e-11
NP_001166282 (OMIM: 125853,611145) zinc transporte ( 320)  285 68.0 4.5e-11
NP_001166285 (OMIM: 125853,611145) zinc transporte ( 320)  285 68.0 4.5e-11
NP_001166286 (OMIM: 125853,611145) zinc transporte ( 320)  285 68.0 4.5e-11
NP_776250 (OMIM: 125853,611145) zinc transporter 8 ( 369)  285 68.0   5e-11
XP_016865238 (OMIM: 607819) PREDICTED: zinc transp ( 681)  280 67.2 1.6e-10
XP_006714735 (OMIM: 607819) PREDICTED: zinc transp ( 722)  280 67.3 1.7e-10
XP_005248626 (OMIM: 607819) PREDICTED: zinc transp ( 724)  280 67.3 1.7e-10
NP_075053 (OMIM: 607819) zinc transporter 5 isofor ( 765)  280 67.3 1.8e-10
NP_115902 (OMIM: 608118,609617) zinc transporter 2 ( 323)  273 65.5 2.5e-10
NP_001004434 (OMIM: 608118,609617) zinc transporte ( 372)  273 65.6 2.8e-10
XP_011520299 (OMIM: 602095) PREDICTED: zinc transp ( 429)  214 53.6 1.3e-06
XP_016878049 (OMIM: 602095) PREDICTED: zinc transp ( 429)  214 53.6 1.3e-06
NP_037441 (OMIM: 602095) zinc transporter 4 isofor ( 429)  214 53.6 1.3e-06
XP_011531405 (OMIM: 602878) PREDICTED: zinc transp ( 274)  210 52.6 1.7e-06
XP_011531404 (OMIM: 602878) PREDICTED: zinc transp ( 315)  210 52.6 1.9e-06
NP_001305880 (OMIM: 602878) zinc transporter 3 iso ( 375)  210 52.7 2.1e-06
NP_001305879 (OMIM: 602878) zinc transporter 3 iso ( 375)  210 52.7 2.1e-06
NP_001305878 (OMIM: 602878) zinc transporter 3 iso ( 383)  210 52.7 2.1e-06
NP_003450 (OMIM: 602878) zinc transporter 3 a [Hom ( 388)  210 52.7 2.2e-06
XP_011539081 (OMIM: 611149) PREDICTED: zinc transp ( 306)  196 49.8 1.3e-05
NP_598003 (OMIM: 611149) zinc transporter 7 [Homo  ( 376)  196 49.8 1.5e-05
NP_001138356 (OMIM: 611149) zinc transporter 7 [Ho ( 376)  196 49.8 1.5e-05
XP_016855889 (OMIM: 611149) PREDICTED: zinc transp ( 376)  196 49.8 1.5e-05
XP_016878050 (OMIM: 602095) PREDICTED: zinc transp ( 199)  156 41.4  0.0028
NP_001307965 (OMIM: 602095) zinc transporter 4 iso ( 187)  155 41.2  0.0031
XP_016878051 (OMIM: 602095) PREDICTED: zinc transp ( 187)  155 41.2  0.0031


>>NP_061183 (OMIM: 611146,613280) zinc transporter 10 [H  (485 aa)
 initn: 3211 init1: 3211 opt: 3211  Z-score: 3552.6  bits: 666.8 E(85289): 3.8e-191
Smith-Waterman score: 3211; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)

               10        20        30        40        50        60
pF1KB7 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAEDPRRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAEDPRRAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 ETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 DASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGAL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 PLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYV
              430       440       450       460       470       480

            
pF1KB7 NRTHF
       :::::
NP_061 NRTHF
            

>>XP_016857173 (OMIM: 611146,613280) PREDICTED: zinc tra  (326 aa)
 initn: 1829 init1: 1829 opt: 1829  Z-score: 2026.8  bits: 383.9 E(85289): 3.7e-106
Smith-Waterman score: 1829; 100.0% identity (100.0% similar) in 273 aa overlap (213-485:54-326)

            190       200       210       220       230       240  
pF1KB7 TAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRGVL
                                     ::::::::::::::::::::::::::::::
XP_016 PSHYLLSEFCCSPPLFAHPFVFLGVTGLGAAGDSFNTQNEPEDMMKKEKKSEALNIRGVL
            30        40        50        60        70        80   

            250       260       270       280       290       300  
pF1KB7 LHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKET
            90       100       110       120       130       140   

            310       320       330       340       350       360  
pF1KB7 AAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDA
           150       160       170       180       190       200   

            370       380       390       400       410       420  
pF1KB7 STKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPL
           210       220       230       240       250       260   

            430       440       450       460       470       480  
pF1KB7 AHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNR
           270       280       290       300       310       320   

          
pF1KB7 THF
       :::
XP_016 THF
          

>>XP_006711500 (OMIM: 611146,613280) PREDICTED: zinc tra  (422 aa)
 initn: 2225 init1: 1829 opt: 1829  Z-score: 2025.3  bits: 384.0 E(85289): 4.5e-106
Smith-Waterman score: 2117; 70.3% identity (79.4% similar) in 485 aa overlap (1-485:1-422)

               10        20        30        40        50        60
pF1KB7 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYI
       ::::::.. ::..: :... .:: ::: .:.:::..: ::.: .:: ..:. .:.  :  
XP_006 MGRYSGRSFRLILMCVVSILLFVMELVIAYVGNSLSLASDAFAVLSHFVSMIIGFF-GVR
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB7 ARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVG
       :    .  ..:::. ::.::::..:..: .:: :.:.:::. :   :.. ..: ::: .:
XP_006 ASNIKQHKKSTYGFLRADVVGAFGNTIFAVALMFSILVEAIKRYINPQKTEEPILVLSAG
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB7 VLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGPQGAEDPRRAA
       ..::. ::.. .:: :      ::                 :   :   :::  .     
XP_006 IIGLFFNVLNYVIFLD------CCY----------------C---AAPKPQGDME-----
     120       130                                140              

              190       200       210       220       230       240
pF1KB7 DPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKEKKSEALNIRG
                                       ::::::::::::::::::::::::::::
XP_006 --------------------------------AGDSFNTQNEPEDMMKKEKKSEALNIRG
                                     150       160       170       

              250       260       270       280       290       300
pF1KB7 VLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIK
       180       190       200       210       220       230       

              310       320       330       340       350       360
pF1KB7 ETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQ
       240       250       260       270       280       290       

              370       380       390       400       410       420
pF1KB7 DASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGAL
       300       310       320       330       340       350       

              430       440       450       460       470       480
pF1KB7 PLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYV
       360       370       380       390       400       410       

            
pF1KB7 NRTHF
       :::::
XP_006 NRTHF
       420  

>>NP_067017 (OMIM: 609521) zinc transporter 1 [Homo sapi  (507 aa)
 initn: 924 init1: 401 opt: 547  Z-score: 606.8  bits: 121.8 E(85289): 4.7e-27
Smith-Waterman score: 905; 36.9% identity (64.3% similar) in 498 aa overlap (1-454:1-485)

               10        20        30        40        50        60
pF1KB7 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYI
       :: .. .  ::: ::.::  :.: :.: . . .:.:.:::::.::::...: :.: :  .
NP_067 MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVG
       :::     . :.:. ::::.::: ::.:::.:::.:..::. :. .:.....: .:: ::
NP_067 ARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQPLVVLGVG
               70        80        90       100       110       120

              130              140       150       160             
pF1KB7 VLGLLVNVVGLLIF-------QDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFG-----
       : ::::::.:: .:       :: .   .   .:... : .  .. ..  ::.       
NP_067 VAGLLVNVLGLCLFHHHSGFSQDSGHGHSHGGHGHGHGLPKGPRV-KSTRPGSSDINVAP
              130       140       150       160        170         

      170       180       190       200       210       220        
pF1KB7 GPQGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMK
       : :: .. .  .  .  ...... :  .. :  : .: :: ..: :   :   ::. :  
NP_067 GEQGPDQEETNTLVANTSNSNGLKLDPADPENPR-SGDTVEVQVNG---NLVREPDHMEL
     180       190       200       210        220          230     

      230       240       250       260         270                
pF1KB7 KEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLK--SE----------DPCN--
       .: ..  ::.:::.:::.:::::::.::..:..:: .  :  ::          :::.  
NP_067 EEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVFY-FSWKGCSEGDFCVNPCFPDPCKAF
         240       250       260       270        280       290    

                           280       290       300       310       
pF1KB7 -----------------WQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNME
                        :  :.::.: :.:: :.: ...::.::.: :::: ::: ....
NP_067 VEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIR
          300       310       320       330       340       350    

       320       330       340       350       360       370       
pF1KB7 ELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHN
       .:...:  : :.  :::.:.:.:....:::: :::     .:....  :...::. ::: 
NP_067 NLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTSYMEVAKTIKDVFHNHGIHA
          360       370       380       390       400       410    

       380       390       400       410       420       430       
pF1KB7 VTIQFENVDLKEPLEQKDLLLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSL
       .::: : ...     .:. .. :.  : .. :: . ::  :.:: :  .  ::.. . :.
NP_067 TTIQPEFASVG----SKSSVVPCELACRTQ-CALKQCC--GTLPQAPSGKDAEKTPAVSI
          420           430       440          450       460       

       440        450       460       470       480     
pF1KB7 DTYG-SDGLSRRDAREVAIEVSLDSCLSDHGQSLNKTQEDQCYVNRTHF
       .    :..: ..  :  :                               
NP_067 SCLELSNNLEKKPRRTKAENIPAVVIEIKNMPNKQPESSL         
       470       480       490       500                

>>NP_001166284 (OMIM: 125853,611145) zinc transporter 8   (320 aa)
 initn: 227 init1: 169 opt: 285  Z-score: 319.7  bits: 68.0 E(85289): 4.5e-11
Smith-Waterman score: 299; 24.6% identity (53.4% similar) in 386 aa overlap (21-404:35-319)

                         10        20        30        40        50
pF1KB7           MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLIS
                                     :..::.:.:....:.:...:. ..: :: :
NP_001 HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTS
           10        20        30        40        50        60    

               60        70        80        90       100       110
pF1KB7 LCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERI
       . ..: . ... .:      :.:. :::..:::     :. ::. . . ... ::  ::.
NP_001 FLLSLFSLWLSSKPPSK-RLTFGWHRAEILGAL-----LSILCIWVVTGVLVYLAC-ERL
           70        80         90            100       110        

              120       130       140       150       160       170
pF1KB7 DDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGP
         :.  . . :.         .: ..::.                               
NP_001 LYPDYQIQATVM---------IIVSSCAV-------------------------------
       120                130                                      

              180       190       200       210       220       230
pF1KB7 QGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKE
               ::.         ..:  : : ..:  : .                    .::
NP_001 --------AAN---------IVL--TVVLHQRCLGHN--------------------HKE
               140                  150                            

              240       250       260        270       280         
pF1KB7 KKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLP-LKSEDPCNWQCYIDPSLTVLMVI
        ...: ..:....:..:: . :. :.:.:.:.:  :  :  ::    :      : .. :
NP_001 VQANA-SVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPI---C------TFIFSI
      160        170       180       190       200                 

     290       300       310       320       330       340         
pF1KB7 IILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATL
       ..:.:.. ..:. . .:.. :::..:.  .   . :: :. ::: .::: :. ...: . 
NP_001 LVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSA
      210       220       230       240       250       260        

     350       360       370        380       390       400        
pF1KB7 HIKYPKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKG
       :.    .:  : .  .: . . ..  .:..:::.:.     :..:    :.:..::    
NP_001 HVATAASRDSQVVRREIAKALSKSFTMHSLTIQMES-----PVDQDPDCLFCEDPCD   
      270       280       290       300            310       320   

      410       420       430       440       450       460        
pF1KB7 CAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQ

>>NP_001166282 (OMIM: 125853,611145) zinc transporter 8   (320 aa)
 initn: 227 init1: 169 opt: 285  Z-score: 319.7  bits: 68.0 E(85289): 4.5e-11
Smith-Waterman score: 299; 24.6% identity (53.4% similar) in 386 aa overlap (21-404:35-319)

                         10        20        30        40        50
pF1KB7           MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLIS
                                     :..::.:.:....:.:...:. ..: :: :
NP_001 HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTS
           10        20        30        40        50        60    

               60        70        80        90       100       110
pF1KB7 LCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERI
       . ..: . ... .:      :.:. :::..:::     :. ::. . . ... ::  ::.
NP_001 FLLSLFSLWLSSKPPSK-RLTFGWHRAEILGAL-----LSILCIWVVTGVLVYLAC-ERL
           70        80         90            100       110        

              120       130       140       150       160       170
pF1KB7 DDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGP
         :.  . . :.         .: ..::.                               
NP_001 LYPDYQIQATVM---------IIVSSCAV-------------------------------
       120                130                                      

              180       190       200       210       220       230
pF1KB7 QGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKE
               ::.         ..:  : : ..:  : .                    .::
NP_001 --------AAN---------IVL--TVVLHQRCLGHN--------------------HKE
               140                  150                            

              240       250       260        270       280         
pF1KB7 KKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLP-LKSEDPCNWQCYIDPSLTVLMVI
        ...: ..:....:..:: . :. :.:.:.:.:  :  :  ::    :      : .. :
NP_001 VQANA-SVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPI---C------TFIFSI
      160        170       180       190       200                 

     290       300       310       320       330       340         
pF1KB7 IILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATL
       ..:.:.. ..:. . .:.. :::..:.  .   . :: :. ::: .::: :. ...: . 
NP_001 LVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSA
      210       220       230       240       250       260        

     350       360       370        380       390       400        
pF1KB7 HIKYPKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKG
       :.    .:  : .  .: . . ..  .:..:::.:.     :..:    :.:..::    
NP_001 HVATAASRDSQVVRREIAKALSKSFTMHSLTIQMES-----PVDQDPDCLFCEDPCD   
      270       280       290       300            310       320   

      410       420       430       440       450       460        
pF1KB7 CAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQ

>>NP_001166285 (OMIM: 125853,611145) zinc transporter 8   (320 aa)
 initn: 227 init1: 169 opt: 285  Z-score: 319.7  bits: 68.0 E(85289): 4.5e-11
Smith-Waterman score: 299; 24.6% identity (53.4% similar) in 386 aa overlap (21-404:35-319)

                         10        20        30        40        50
pF1KB7           MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLIS
                                     :..::.:.:....:.:...:. ..: :: :
NP_001 HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTS
           10        20        30        40        50        60    

               60        70        80        90       100       110
pF1KB7 LCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERI
       . ..: . ... .:      :.:. :::..:::     :. ::. . . ... ::  ::.
NP_001 FLLSLFSLWLSSKPPSK-RLTFGWHRAEILGAL-----LSILCIWVVTGVLVYLAC-ERL
           70        80         90            100       110        

              120       130       140       150       160       170
pF1KB7 DDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGP
         :.  . . :.         .: ..::.                               
NP_001 LYPDYQIQATVM---------IIVSSCAV-------------------------------
       120                130                                      

              180       190       200       210       220       230
pF1KB7 QGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKE
               ::.         ..:  : : ..:  : .                    .::
NP_001 --------AAN---------IVL--TVVLHQRCLGHN--------------------HKE
               140                  150                            

              240       250       260        270       280         
pF1KB7 KKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLP-LKSEDPCNWQCYIDPSLTVLMVI
        ...: ..:....:..:: . :. :.:.:.:.:  :  :  ::    :      : .. :
NP_001 VQANA-SVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPI---C------TFIFSI
      160        170       180       190       200                 

     290       300       310       320       330       340         
pF1KB7 IILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATL
       ..:.:.. ..:. . .:.. :::..:.  .   . :: :. ::: .::: :. ...: . 
NP_001 LVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSA
      210       220       230       240       250       260        

     350       360       370        380       390       400        
pF1KB7 HIKYPKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKG
       :.    .:  : .  .: . . ..  .:..:::.:.     :..:    :.:..::    
NP_001 HVATAASRDSQVVRREIAKALSKSFTMHSLTIQMES-----PVDQDPDCLFCEDPCD   
      270       280       290       300            310       320   

      410       420       430       440       450       460        
pF1KB7 CAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQ

>>NP_001166286 (OMIM: 125853,611145) zinc transporter 8   (320 aa)
 initn: 227 init1: 169 opt: 285  Z-score: 319.7  bits: 68.0 E(85289): 4.5e-11
Smith-Waterman score: 299; 24.6% identity (53.4% similar) in 386 aa overlap (21-404:35-319)

                         10        20        30        40        50
pF1KB7           MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLIS
                                     :..::.:.:....:.:...:. ..: :: :
NP_001 HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTS
           10        20        30        40        50        60    

               60        70        80        90       100       110
pF1KB7 LCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERI
       . ..: . ... .:      :.:. :::..:::     :. ::. . . ... ::  ::.
NP_001 FLLSLFSLWLSSKPPSK-RLTFGWHRAEILGAL-----LSILCIWVVTGVLVYLAC-ERL
           70        80         90            100       110        

              120       130       140       150       160       170
pF1KB7 DDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGP
         :.  . . :.         .: ..::.                               
NP_001 LYPDYQIQATVM---------IIVSSCAV-------------------------------
       120                130                                      

              180       190       200       210       220       230
pF1KB7 QGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKE
               ::.         ..:  : : ..:  : .                    .::
NP_001 --------AAN---------IVL--TVVLHQRCLGHN--------------------HKE
               140                  150                            

              240       250       260        270       280         
pF1KB7 KKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLP-LKSEDPCNWQCYIDPSLTVLMVI
        ...: ..:....:..:: . :. :.:.:.:.:  :  :  ::    :      : .. :
NP_001 VQANA-SVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPI---C------TFIFSI
      160        170       180       190       200                 

     290       300       310       320       330       340         
pF1KB7 IILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATL
       ..:.:.. ..:. . .:.. :::..:.  .   . :: :. ::: .::: :. ...: . 
NP_001 LVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSA
      210       220       230       240       250       260        

     350       360       370        380       390       400        
pF1KB7 HIKYPKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKG
       :.    .:  : .  .: . . ..  .:..:::.:.     :..:    :.:..::    
NP_001 HVATAASRDSQVVRREIAKALSKSFTMHSLTIQMES-----PVDQDPDCLFCEDPCD   
      270       280       290       300            310       320   

      410       420       430       440       450       460        
pF1KB7 CAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQ

>>NP_776250 (OMIM: 125853,611145) zinc transporter 8 iso  (369 aa)
 initn: 227 init1: 169 opt: 285  Z-score: 318.9  bits: 68.0 E(85289): 5e-11
Smith-Waterman score: 299; 24.6% identity (53.4% similar) in 386 aa overlap (21-404:84-368)

                         10        20        30        40        50
pF1KB7           MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLIS
                                     :..::.:.:....:.:...:. ..: :: :
NP_776 HSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTS
            60        70        80        90       100       110   

               60        70        80        90       100       110
pF1KB7 LCVGLSAGYIARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERI
       . ..: . ... .:      :.:. :::..:::     :. ::. . . ... ::  ::.
NP_776 FLLSLFSLWLSSKPPSK-RLTFGWHRAEILGAL-----LSILCIWVVTGVLVYLAC-ERL
           120       130        140            150       160       

              120       130       140       150       160       170
pF1KB7 DDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPGAFGGP
         :.  . . :.         .: ..::.                               
NP_776 LYPDYQIQATVM---------IIVSSCAV-------------------------------
        170                180                                     

              180       190       200       210       220       230
pF1KB7 QGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFNTQNEPEDMMKKE
               ::.         ..:  : : ..:  : .                    .::
NP_776 --------AAN---------IVL--TVVLHQRCLGHN--------------------HKE
                         190         200                           

              240       250       260        270       280         
pF1KB7 KKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLP-LKSEDPCNWQCYIDPSLTVLMVI
        ...: ..:....:..:: . :. :.:.:.:.:  :  :  ::    :      : .. :
NP_776 VQANA-SVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPI---C------TFIFSI
       210        220       230       240       250                

     290       300       310       320       330       340         
pF1KB7 IILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATL
       ..:.:.. ..:. . .:.. :::..:.  .   . :: :. ::: .::: :. ...: . 
NP_776 LVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSA
       260       270       280       290       300       310       

     350       360       370        380       390       400        
pF1KB7 HIKYPKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPLEQKDLLLLCNSPCISKG
       :.    .:  : .  .: . . ..  .:..:::.:.     :..:    :.:..::    
NP_776 HVATAASRDSQVVRREIAKALSKSFTMHSLTIQMES-----PVDQDPDCLFCEDPCD   
       320       330       340       350            360            

      410       420       430       440       450       460        
pF1KB7 CAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYGSDGLSRRDAREVAIEVSLDSCLSDHGQ

>>XP_016865238 (OMIM: 607819) PREDICTED: zinc transporte  (681 aa)
 initn: 381 init1: 124 opt: 280  Z-score: 309.8  bits: 67.2 E(85289): 1.6e-10
Smith-Waterman score: 333; 29.0% identity (57.3% similar) in 321 aa overlap (10-329:377-629)

                                    10        20        30         
pF1KB7                      MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLS
                                     .....: :.. :  .::  : : ::..:.:
XP_016 MGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLIS
        350       360       370       380       390       400      

      40        50        60         70        80        90        
pF1KB7 DSFNMLSDLISLCVGLSAGYIAR-RPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFV
       :.:.:: :  .: .:: :. ..: . :: ::  :::.: :..... :..:: .. : .:.
XP_016 DGFHMLFDCSALVMGLFAALMSRWKATRIFS--YGYGRIEILSGFINGLFLIVIAFFVFM
        410       420       430         440       450       460    

      100       110       120       130       140       150        
pF1KB7 EAVLRLARPERIDDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQL
       :.: ::  : ..:  ...  :.: ::.::..:.     ::  :.   ...:.        
XP_016 ESVARLIDPPELDT-HMLTPVSVGGLIVNLIGI-----CA--FS---HAHSH--------
          470        480       490              500                

      160       170       180       190       200       210        
pF1KB7 AEGCVPGAFGGPQGAEDPRRAADPTAPGSDSAVTLRGTSVERKREKGATVFANVAGDSFN
              : :. ::          .  .:: .   ..  .. . ..:     . :: ..:
XP_016 -------AHGASQG----------SCHSSDHS---HSHHMHGHSDHGHGHSHGSAGGGMN
                510                 520          530       540     

      220       230       240       250       260       270        
pF1KB7 TQNEPEDMMKKEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKSEDPCNWQCY
       .                 :.:::.:::..:.:::. :.......        .  .:   
XP_016 A-----------------NMRGVFLHVLADTLGSIGVIVSTVLI--------EQFGW-FI
                          550       560       570                  

      280       290       300       310       320       330        
pF1KB7 IDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMSKLSAVPGISSVHEVHIW
        ::  .....:.:. :. ::::..  .::  .:   . .::   :  : ::         
XP_016 ADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYE-KELHIALEKVTGILKDAGVNNL
     580       590       600       610        620       630        

      340       350       360       370       380       390        
pF1KB7 ELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHNVTIQFENVDLKEPLEQKDLLL
                                                                   
XP_016 TIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM                 
      640       650       660       670       680                  




485 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:28:47 2016 done: Fri Nov  4 07:28:48 2016
 Total Scan time:  9.790 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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