Result of FASTA (omim) for pF1KB7393
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7393, 414 aa
  1>>>pF1KB7393 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0850+/-0.000495; mu= 13.3586+/- 0.030
 mean_var=118.7233+/-26.208, 0's: 0 Z-trim(111.3): 283  B-trim: 732 in 1/51
 Lambda= 0.117708
 statistics sampled from 19453 (19836) to 19453 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.233), width:  16
 Scan time:  8.830

The best scores are:                                      opt bits E(85289)
NP_689542 (OMIM: 609193) leucine-rich repeat prote ( 414) 2728 475.1 1.4e-133
NP_982292 (OMIM: 609193) leucine-rich repeat prote ( 146)  621 116.9 3.4e-26
XP_016875972 (OMIM: 610368) PREDICTED: leucine-ric ( 731)  265 57.1 1.7e-07
NP_001157685 (OMIM: 610368) leucine-rich repeat an ( 696)  259 56.0 3.4e-07
NP_055931 (OMIM: 610368) leucine-rich repeat and c ( 728)  259 56.0 3.5e-07
NP_001157683 (OMIM: 610368) leucine-rich repeat an ( 763)  259 56.1 3.6e-07
NP_036557 (OMIM: 179555) ras suppressor protein 1  ( 277)  250 54.1   5e-07
NP_689937 (OMIM: 179555) ras suppressor protein 1  ( 224)  242 52.7 1.1e-06
NP_060573 (OMIM: 612890) volume-regulated anion ch ( 858)  250 54.6 1.1e-06
XP_016857090 (OMIM: 612890) PREDICTED: volume-regu ( 858)  250 54.6 1.1e-06
XP_016857089 (OMIM: 612890) PREDICTED: volume-regu ( 858)  250 54.6 1.1e-06
NP_001127951 (OMIM: 612890) volume-regulated anion ( 858)  250 54.6 1.1e-06
XP_016857088 (OMIM: 612890) PREDICTED: volume-regu ( 858)  250 54.6 1.1e-06
XP_016857091 (OMIM: 612890) PREDICTED: volume-regu ( 858)  250 54.6 1.1e-06
XP_011539991 (OMIM: 612890) PREDICTED: volume-regu ( 858)  250 54.6 1.1e-06
XP_016866486 (OMIM: 608195) PREDICTED: leucine-ric ( 331)  239 52.3 2.1e-06
XP_011513028 (OMIM: 608195) PREDICTED: leucine-ric ( 524)  239 52.5 2.9e-06
NP_060684 (OMIM: 608195) leucine-rich repeat-conta ( 524)  239 52.5 2.9e-06
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536)  234 51.7 5.3e-06
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  234 51.7 5.6e-06
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  234 51.7 5.6e-06
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582)  234 51.7 5.6e-06
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582)  234 51.7 5.6e-06
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582)  234 51.7 5.6e-06
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  234 51.7 5.6e-06
XP_011513029 (OMIM: 608195) PREDICTED: leucine-ric ( 465)  231 51.1 6.8e-06
XP_005252609 (OMIM: 179555) PREDICTED: ras suppres ( 277)  219 48.9 1.9e-05
XP_011542154 (OMIM: 605352) PREDICTED: malignant f (1003)  220 49.6 4.3e-05
NP_004216 (OMIM: 605352) malignant fibrous histioc (1052)  220 49.6 4.4e-05
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690)  216 48.7 5.3e-05
NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-pr ( 696)  216 48.7 5.3e-05
NP_001005374 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723)  216 48.7 5.4e-05
NP_001005373 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723)  216 48.7 5.4e-05
NP_612370 (OMIM: 610933,614436) E3 ubiquitin-prote ( 723)  216 48.7 5.4e-05
XP_016870772 (OMIM: 610933,614436) PREDICTED: E3 u ( 723)  216 48.7 5.4e-05
XP_005252152 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
XP_011517166 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
XP_011517165 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
NP_001120717 (OMIM: 608360,613506) volume-regulate ( 810)  216 48.8 5.9e-05
XP_011517167 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
XP_006717249 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
NP_062540 (OMIM: 608360,613506) volume-regulated a ( 810)  216 48.8 5.9e-05
NP_001120716 (OMIM: 608360,613506) volume-regulate ( 810)  216 48.8 5.9e-05
XP_005252153 (OMIM: 608360,613506) PREDICTED: volu ( 810)  216 48.8 5.9e-05
XP_016857384 (OMIM: 614453) PREDICTED: leucine-ric (1255)  217 49.1 7.2e-05
XP_016857383 (OMIM: 614453) PREDICTED: leucine-ric (1438)  217 49.2 7.9e-05
XP_016857382 (OMIM: 614453) PREDICTED: leucine-ric (1472)  217 49.2   8e-05
XP_016857381 (OMIM: 614453) PREDICTED: leucine-ric (1490)  217 49.2 8.1e-05
NP_001317564 (OMIM: 614453) leucine-rich repeat-co (1495)  217 49.2 8.1e-05
XP_016857379 (OMIM: 614453) PREDICTED: leucine-ric (1528)  217 49.2 8.3e-05


>>NP_689542 (OMIM: 609193) leucine-rich repeat protein 1  (414 aa)
 initn: 2728 init1: 2728 opt: 2728  Z-score: 2519.1  bits: 475.1 E(85289): 1.4e-133
Smith-Waterman score: 2728; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)

               10        20        30        40        50        60
pF1KB7 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 STLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 STLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LFGNTFEQPKVLPVIKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LFGNTFEQPKVLPVIKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCG
              310       320       330       340       350       360

              370       380       390       400       410    
pF1KB7 RFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK
              370       380       390       400       410    

>>NP_982292 (OMIM: 609193) leucine-rich repeat protein 1  (146 aa)
 initn: 634 init1: 617 opt: 621  Z-score: 591.2  bits: 116.9 E(85289): 3.4e-26
Smith-Waterman score: 621; 87.6% identity (93.8% similar) in 113 aa overlap (1-112:1-113)

               10        20        30        40        50        60
pF1KB7 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY
               10        20        30        40        50        60

               70        80        90        100       110         
pF1KB7 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSK-AISSSLKGFLSAMRLAHRGCNVDTP
       :::::::::::::::::::::::::::::::::: .:  : ... :  :...:       
NP_982 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKDSIWLSYHSIPSLPRFGYRKNLCLWK
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 VSTLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSL
                                                                   
NP_982 ILSELFHSRNYYHESAFCCPHCGLSR                                  
              130       140                                        

>>XP_016875972 (OMIM: 610368) PREDICTED: leucine-rich re  (731 aa)
 initn: 273 init1: 171 opt: 265  Z-score: 255.5  bits: 57.1 E(85289): 1.7e-07
Smith-Waterman score: 265; 36.8% identity (63.8% similar) in 163 aa overlap (166-327:109-266)

         140       150       160       170       180       190     
pF1KB7 TKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPAT
                                     ::.: :..  . ::. :.: :: :. .: .
XP_016 SARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEA
       80        90       100       110       120       130        

         200       210       220       230       240       250     
pF1KB7 IGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLK
       : .:  :  :::. :.: .. . ::       :. :  :.::. .:: .. ::..: .: 
XP_016 IVNLQMLTYLNLSRNQLSALPACLCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELD
      140       150       160           170       180       190    

         260       270       280       290       300        310    
pF1KB7 LDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGN-TFEQPKVLPV
       .. ::.  .: .:::: .:: :.. :: :  ::.:. .:::  .:.  : ..  :  .  
XP_016 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNKVLVIPICFRE
          200       210       220       230       240       250    

          320       330       340       350       360       370    
pF1KB7 IKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTM
       .: :  . :::..                                               
XP_016 MK-QLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQH
           260       270       280       290       300       310   

>>NP_001157685 (OMIM: 610368) leucine-rich repeat and ca  (696 aa)
 initn: 291 init1: 165 opt: 259  Z-score: 250.3  bits: 56.0 E(85289): 3.4e-07
Smith-Waterman score: 259; 36.2% identity (63.2% similar) in 163 aa overlap (166-327:109-266)

         140       150       160       170       180       190     
pF1KB7 TKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPAT
                                     ::.: :..  . ::. :.: :: :. .: .
NP_001 SARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEA
       80        90       100       110       120       130        

         200       210       220       230       240       250     
pF1KB7 IGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLK
       : .:  :  :::. :.: .. . ::       :. :  :.::. .:: .. ::..: .: 
NP_001 IVNLQMLTYLNLSRNQLSALPACLCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELD
      140       150       160           170       180       190    

         260       270       280       290       300        310    
pF1KB7 LDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGN-TFEQPKVLPV
       .. ::.  .: .:::: .:: :.. :: :  ::.:. .: :  .:.  : ..  :  .  
NP_001 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNKVLVIPICFRE
          200       210       220       230       240       250    

          320       330       340       350       360       370    
pF1KB7 IKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTM
       .: :  . :::..                                               
NP_001 MK-QLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQH
           260       270       280       290       300       310   

>>NP_055931 (OMIM: 610368) leucine-rich repeat and calpo  (728 aa)
 initn: 291 init1: 165 opt: 259  Z-score: 250.0  bits: 56.0 E(85289): 3.5e-07
Smith-Waterman score: 259; 36.2% identity (63.2% similar) in 163 aa overlap (166-327:109-266)

         140       150       160       170       180       190     
pF1KB7 TKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPAT
                                     ::.: :..  . ::. :.: :: :. .: .
NP_055 SARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEA
       80        90       100       110       120       130        

         200       210       220       230       240       250     
pF1KB7 IGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLK
       : .:  :  :::. :.: .. . ::       :. :  :.::. .:: .. ::..: .: 
NP_055 IVNLQMLTYLNLSRNQLSALPACLCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELD
      140       150       160           170       180       190    

         260       270       280       290       300        310    
pF1KB7 LDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGN-TFEQPKVLPV
       .. ::.  .: .:::: .:: :.. :: :  ::.:. .: :  .:.  : ..  :  .  
NP_055 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNKVLVIPICFRE
          200       210       220       230       240       250    

          320       330       340       350       360       370    
pF1KB7 IKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTM
       .: :  . :::..                                               
NP_055 MK-QLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQH
           260       270       280       290       300       310   

>>NP_001157683 (OMIM: 610368) leucine-rich repeat and ca  (763 aa)
 initn: 291 init1: 165 opt: 259  Z-score: 249.7  bits: 56.1 E(85289): 3.6e-07
Smith-Waterman score: 259; 36.2% identity (63.2% similar) in 163 aa overlap (166-327:109-266)

         140       150       160       170       180       190     
pF1KB7 TKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPAT
                                     ::.: :..  . ::. :.: :: :. .: .
NP_001 SARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEA
       80        90       100       110       120       130        

         200       210       220       230       240       250     
pF1KB7 IGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLK
       : .:  :  :::. :.: .. . ::       :. :  :.::. .:: .. ::..: .: 
NP_001 IVNLQMLTYLNLSRNQLSALPACLCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELD
      140       150       160           170       180       190    

         260       270       280       290       300        310    
pF1KB7 LDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGN-TFEQPKVLPV
       .. ::.  .: .:::: .:: :.. :: :  ::.:. .: :  .:.  : ..  :  .  
NP_001 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNKVLVIPICFRE
          200       210       220       230       240       250    

          320       330       340       350       360       370    
pF1KB7 IKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTM
       .: :  . :::..                                               
NP_001 MK-QLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQH
           260       270       280       290       300       310   

>>NP_036557 (OMIM: 179555) ras suppressor protein 1 isof  (277 aa)
 initn: 315 init1: 175 opt: 250  Z-score: 247.1  bits: 54.1 E(85289): 5e-07
Smith-Waterman score: 250; 27.4% identity (57.5% similar) in 252 aa overlap (96-342:1-250)

          70        80        90       100       110         120   
pF1KB7 IEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGC--NVDTPVSTL
                                     .:.::: ..   :  ..      :  .:..
NP_036                               MSKSLKKLVEESREKNQPEVDMSDRGISNM
                                             10        20        30

           130       140       150         160       170       180 
pF1KB7 TPVKTSEFENFKTKMVITSKKDYPLSKNFPY--SLEHLQTSYCGLVRVDMRMLCLKSLRK
         :.     .  :..:.. .:   .  :.    .:: :.     . ..  ..  :..:..
NP_036 LDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKH
               40        50        60        70        80        90

             190       200       210       220       230       240 
pF1KB7 LDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKAL
       :.:. :... ::  .:.:  :. :.:. :.:   :.      :  .::.: :: : .. :
NP_036 LNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLT-TLRALYLSDNDFEIL
              100       110       120       130        140         

             250       260       270       280       290       300 
pF1KB7 PVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDL
       : .. .: .:. :.: ::.::..: .::.: .:. :    :.:  :: :. ::.:     
NP_036 PPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQ
     150       160       170       180       190       200         

             310        320       330       340       350       360
pF1KB7 FGNTFEQPKVLPVI-KLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCG
         .. ..: : :.  ..:  .. .    :.  .. . :: :.                  
NP_036 VFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYL-YGRHMQANPEPPKKNNDKSKKIS
     210       220       230       240        250       260        

              370       380       390       400       410    
pF1KB7 RFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK
                                                             
NP_036 RKPLAAKNR                                             
      270                                                    

>>NP_689937 (OMIM: 179555) ras suppressor protein 1 isof  (224 aa)
 initn: 252 init1: 175 opt: 242  Z-score: 241.0  bits: 52.7 E(85289): 1.1e-06
Smith-Waterman score: 242; 32.1% identity (62.5% similar) in 168 aa overlap (176-342:32-197)

         150       160       170       180       190       200     
pF1KB7 YPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQEL
                                     :..:..:.:. :... ::  .:.:  :. :
NP_689 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL
              10        20        30        40        50        60 

         210       220       230       240       250       260     
pF1KB7 NLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFP
       .:. :.:   :.      :  .::.: :: : .. :: .. .: .:. :.: ::.::..:
NP_689 DLTYNNLSENSLPGNFFYLT-TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLP
              70        80         90       100       110       120

         270       280       290       300       310        320    
pF1KB7 CKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVI-KLQAPLTLL
        .::.: .:. :    :.:  :: :. ::.:       .. ..: : :.  ..:  .. .
NP_689 KEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHV
              130       140       150       160       170       180

          330       340       350       360       370       380    
pF1KB7 ESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVV
           :.  .. . :: :.                                          
NP_689 FEYIRSETYKYL-YGRHMQANPEPPKKNNDKSKKISRKPLAAKNR               
              190        200       210       220                   

>>NP_060573 (OMIM: 612890) volume-regulated anion channe  (858 aa)
 initn: 247 init1: 150 opt: 250  Z-score: 240.8  bits: 54.6 E(85289): 1.1e-06
Smith-Waterman score: 250; 28.0% identity (58.8% similar) in 289 aa overlap (62-337:535-814)

              40        50        60        70          80         
pF1KB7 LCQQTSRSQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVD--EGKATVRLKEPPVD
                                     ::.... . .::.:  :  : : : .   .
NP_060 IPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYLLKNLRE
          510       520       530       540       550       560    

      90          100       110        120       130       140     
pF1KB7 ICLSKAISS---SLKGFLSAMRLAH-RGCNVDTPVSTLTPVKTSEFENFKTKMVITSKKD
       . :   ..:   .. :. :  .: : .  .: . . : .: . ..     ::.:: .   
NP_060 LYLIGNLNSENNKMIGLESLRELRHLKILHVKSNL-TKVPSNITDVAPHLTKLVIHNDGT
          570       580       590        600       610       620   

         150          160       170       180       190         200
pF1KB7 YPLSKNF---PYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIG--DLI
         :  :     ... .:. . : : :.   .. :..:..:::. :.:. .   :.   : 
NP_060 KLLVLNSLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLK
           630       640       650       660       670       680   

              210       220       230       240       250       260
pF1KB7 HLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNE
       .:  :.:  :.. ..  .. :    :.:.:: .:.::...:::   .::.:. : .. :.
NP_060 RLTCLKLWHNKIVTIPPSITHV---KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNN
           690       700          710       720       730       740

              270       280       290        300       310         
pF1KB7 LIQFPCKIGQLINLRFLSAARNKLPFLPSE-FRNLSLEYLDLFGNTFEQPKVLPV-IKLQ
       . ..: .:: : ::. :  . ::. .::.. :. ..:. :.:  : . .   ::  .   
NP_060 ISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITS---LPEKVGQL
              750       760       770       780          790       

      320       330       340       350       360       370        
pF1KB7 APLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHS
       . :: :: ..  .  .:.:                                         
NP_060 SQLTQLELKGNCL--DRLPAQLGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINIPFA
       800       810         820       830       840       850     

>>XP_016857090 (OMIM: 612890) PREDICTED: volume-regulate  (858 aa)
 initn: 247 init1: 150 opt: 250  Z-score: 240.8  bits: 54.6 E(85289): 1.1e-06
Smith-Waterman score: 250; 28.0% identity (58.8% similar) in 289 aa overlap (62-337:535-814)

              40        50        60        70          80         
pF1KB7 LCQQTSRSQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVD--EGKATVRLKEPPVD
                                     ::.... . .::.:  :  : : : .   .
XP_016 IPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYLLKNLRE
          510       520       530       540       550       560    

      90          100       110        120       130       140     
pF1KB7 ICLSKAISS---SLKGFLSAMRLAH-RGCNVDTPVSTLTPVKTSEFENFKTKMVITSKKD
       . :   ..:   .. :. :  .: : .  .: . . : .: . ..     ::.:: .   
XP_016 LYLIGNLNSENNKMIGLESLRELRHLKILHVKSNL-TKVPSNITDVAPHLTKLVIHNDGT
          570       580       590        600       610       620   

         150          160       170       180       190         200
pF1KB7 YPLSKNF---PYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIG--DLI
         :  :     ... .:. . : : :.   .. :..:..:::. :.:. .   :.   : 
XP_016 KLLVLNSLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLK
           630       640       650       660       670       680   

              210       220       230       240       250       260
pF1KB7 HLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNE
       .:  :.:  :.. ..  .. :    :.:.:: .:.::...:::   .::.:. : .. :.
XP_016 RLTCLKLWHNKIVTIPPSITHV---KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNN
           690       700          710       720       730       740

              270       280       290        300       310         
pF1KB7 LIQFPCKIGQLINLRFLSAARNKLPFLPSE-FRNLSLEYLDLFGNTFEQPKVLPV-IKLQ
       . ..: .:: : ::. :  . ::. .::.. :. ..:. :.:  : . .   ::  .   
XP_016 ISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITS---LPEKVGQL
              750       760       770       780          790       

      320       330       340       350       360       370        
pF1KB7 APLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHS
       . :: :: ..  .  .:.:                                         
XP_016 SQLTQLELKGNCL--DRLPAQLGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINIPFA
       800       810         820       830       840       850     




414 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:21:19 2016 done: Fri Nov  4 07:21:20 2016
 Total Scan time:  8.830 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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