Result of FASTA (omim) for pF1KB7381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7381, 462 aa
  1>>>pF1KB7381 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2362+/-0.000351; mu= 1.3600+/- 0.022
 mean_var=264.1458+/-54.270, 0's: 0 Z-trim(123.2): 42  B-trim: 403 in 1/52
 Lambda= 0.078914
 statistics sampled from 42597 (42643) to 42597 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.5), width:  16
 Scan time: 12.190

The best scores are:                                      opt bits E(85289)
NP_001529 (OMIM: 116800,602438) heat shock factor  ( 462) 3168 373.6 6.2e-103
NP_001035757 (OMIM: 116800,602438) heat shock fact ( 492) 1679 204.1   7e-52
XP_016868866 (OMIM: 140580) PREDICTED: heat shock  ( 489)  890 114.3 7.7e-25
XP_005272373 (OMIM: 140580) PREDICTED: heat shock  ( 517)  890 114.3   8e-25
NP_005517 (OMIM: 140580) heat shock factor protein ( 529)  890 114.3 8.1e-25
XP_005272372 (OMIM: 140580) PREDICTED: heat shock  ( 557)  890 114.3 8.4e-25
XP_005272374 (OMIM: 140580) PREDICTED: heat shock  ( 310)  876 112.5 1.7e-24
NP_001230023 (OMIM: 140581) heat shock factor prot ( 230)  649 86.5   8e-17
NP_001129036 (OMIM: 140581) heat shock factor prot ( 518)  649 86.9 1.5e-16
NP_004497 (OMIM: 140581) heat shock factor protein ( 536)  649 86.9 1.5e-16


>>NP_001529 (OMIM: 116800,602438) heat shock factor prot  (462 aa)
 initn: 3168 init1: 3168 opt: 3168  Z-score: 1968.9  bits: 373.6 E(85289): 6.2e-103
Smith-Waterman score: 3168; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 IQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVVQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 AILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP
              370       380       390       400       410       420

              430       440       450       460  
pF1KB7 LLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP
              430       440       450       460  

>>NP_001035757 (OMIM: 116800,602438) heat shock factor p  (492 aa)
 initn: 2850 init1: 1679 opt: 1679  Z-score: 1052.4  bits: 204.1 E(85289): 7e-52
Smith-Waterman score: 2803; 87.6% identity (90.2% similar) in 492 aa overlap (1-462:1-492)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
              190       200       210       220       230       240

                 250            260              270           280 
pF1KB7 IQSP---STYSLSQRQ-----IWALALTGPG------APSSL-TSQKTLHPLR----GPG
       ::::   .. .:: ..     :  .   .:.      .:::    .: :  :.    .::
NP_001 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG
              250       260       270       280       290       300

                        290       300       310       320       330
pF1KB7 -------FLPP----VMAGAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
               : :      . :::::::::::::::::::::::::::::::::::::::::
NP_001 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
              310       320       330       340       350       360

              340       350       360       370       380       390
pF1KB7 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
              370       380       390       400       410       420

              400       410       420       430       440       450
pF1KB7 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
              430       440       450       460       470       480

              460  
pF1KB7 ASYLGPEASPSP
       ::::::::::::
NP_001 ASYLGPEASPSP
              490  

>>XP_016868866 (OMIM: 140580) PREDICTED: heat shock fact  (489 aa)
 initn: 715 init1: 587 opt: 890  Z-score: 567.0  bits: 114.3 E(85289): 7.7e-25
Smith-Waterman score: 903; 38.9% identity (59.8% similar) in 483 aa overlap (9-451:7-486)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
XP_016   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
XP_016 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
XP_016 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
XP_016 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280                
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPG---------FLPPVM
        ::   ::.  : :     :.: .::   :..:      :. .::           : : 
XP_016 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPGGSIDERPLSSSPLVR
       240       250       260        270       280       290      

       290         300            310           320       330      
pF1KB7 AGAPPPLPVAV--VQAILEGKGS-----FSPEGPRNA----QQPEPGDPREIPD-RGPLG
       .   :: :     :.    :. :     .:: .  ..    ..: :..   . : ::   
XP_016 VKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTD
        300       310       320       330       340       350      

         340       350         360       370             380       
pF1KB7 LESGDRSPESLLPPM--LLQPPQESVEPAGPLDVLGPSLQGREWTL------MDLDMELS
        :.   ::     :   :     .. : .  ::..  .:.. .  :      .: .  :.
XP_016 TEGRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLD
        360       370       380       390       400       410      

       390         400            410       420       430       440
pF1KB7 LMQP--LVPERGEPEL-----AVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGAL
       :..:   ::. . :.:     ... : ::.    :  .     :  .:: . : ..:.. 
XP_016 LFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSAGALHSAA-AVPAGP
        420       430       440       450       460        470     

              450       460  
pF1KB7 TIYSTPESRTASYLGPEASPSP
        . .  :.: :           
XP_016 RLRGHREQRPAGAV        
         480                 

>>XP_005272373 (OMIM: 140580) PREDICTED: heat shock fact  (517 aa)
 initn: 715 init1: 587 opt: 890  Z-score: 566.7  bits: 114.3 E(85289): 8e-25
Smith-Waterman score: 890; 46.5% identity (68.0% similar) in 325 aa overlap (9-328:7-321)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
XP_005   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
XP_005 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
XP_005 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
XP_005 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280       290      
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPV
        ::   ::.  : :     :.: .::   :..:      :. .::       :.    :.
XP_005 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPG-------GSIDERPL
       240       250       260        270       280                

        300        310       320       330       340       350     
pF1KB7 AVVQAI-LEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPP
       .    . .. .    :..:: ...  :: :  .                           
XP_005 SSSPLVRVKEEPPSPPQSPR-VEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTAL
     290       300        310       320       330       340        

         360       370       380       390       400       410     
pF1KB7 QESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDP
                                                                   
XP_005 TDARGHTDTEGRPPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQP
      350       360       370       380       390       400        

>>NP_005517 (OMIM: 140580) heat shock factor protein 1 [  (529 aa)
 initn: 728 init1: 587 opt: 890  Z-score: 566.5  bits: 114.3 E(85289): 8.1e-25
Smith-Waterman score: 902; 39.1% identity (58.6% similar) in 471 aa overlap (9-423:7-475)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
NP_005   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
NP_005 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
NP_005 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
NP_005 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280                
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPG---------FLPPVM
        ::   ::.  : :     :.: .::   :..:      :. .::           : : 
NP_005 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPGGSIDERPLSSSPLVR
       240       250       260        270       280       290      

       290         300            310           320       330      
pF1KB7 AGAPPPLPVAV--VQAILEGKGS-----FSPEGPRNA----QQPEPGDPREIPD-RGPLG
       .   :: :     :.    :. :     .:: .  ..    ..: :..   . : ::   
NP_005 VKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTD
        300       310       320       330       340       350      

         340                                    350       360      
pF1KB7 LESGDRSPESLLPP-----------------------------MLLQPPQESVEPAGPLD
        :.   ::     :                              .:.    ::. .. ::
NP_005 TEGRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLD
        360       370       380       390       400       410      

        370       380       390       400       410         420    
pF1KB7 VLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPT--LGAPLLLD
       ...::.   . .: :::  :. .: :.  .  :.      .::. ::. .   . ::.: 
NP_005 LFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLL
        420       430       440       450       460       470      

          430       440       450       460                 
pF1KB7 VQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP               
                                                            
NP_005 DPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
        480       490       500       510       520         

>>XP_005272372 (OMIM: 140580) PREDICTED: heat shock fact  (557 aa)
 initn: 728 init1: 587 opt: 890  Z-score: 566.2  bits: 114.3 E(85289): 8.4e-25
Smith-Waterman score: 890; 46.5% identity (68.0% similar) in 325 aa overlap (9-328:7-321)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
XP_005   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
XP_005 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
XP_005 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
XP_005 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280       290      
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPV
        ::   ::.  : :     :.: .::   :..:      :. .::       :.    :.
XP_005 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPG-------GSIDERPL
       240       250       260        270       280                

        300        310       320       330       340       350     
pF1KB7 AVVQAI-LEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPP
       .    . .. .    :..:: ...  :: :  .                           
XP_005 SSSPLVRVKEEPPSPPQSPR-VEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTAL
     290       300        310       320       330       340        

         360       370       380       390       400       410     
pF1KB7 QESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDP
                                                                   
XP_005 TDARGHTDTEGRPPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQP
      350       360       370       380       390       400        

>>XP_005272374 (OMIM: 140580) PREDICTED: heat shock fact  (310 aa)
 initn: 662 init1: 587 opt: 876  Z-score: 561.0  bits: 112.5 E(85289): 1.7e-24
Smith-Waterman score: 876; 51.6% identity (72.2% similar) in 277 aa overlap (9-281:7-281)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
XP_005   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
XP_005 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
XP_005 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
XP_005 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280       290      
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPV
        ::   ::.  : :     :.: .::   :..:      :. .::               
XP_005 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPGGSIDESPHGRQGPHG
       240       250       260        270       280       290      

        300       310       320       330       340       350      
pF1KB7 AVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQ
                                                                   
XP_005 HRGPASLPPAHLHP                                              
        300       310                                              

>>NP_001230023 (OMIM: 140581) heat shock factor protein   (230 aa)
 initn: 625 init1: 625 opt: 649  Z-score: 423.0  bits: 86.5 E(85289): 8e-17
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (15-214:5-203)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
                     : :::::.:::.:: .  :...: :: .: :::: :..:::::.::
NP_001           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
                         10        20        30        40        50

               70        80        90        100       110         
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
       .::::.:::::::::::::::::: :..: ... :::  :::::: : .:...::: ..:
NP_001 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
               60        70         80        90       100         

     120       130       140       150       160       170         
pF1KB7 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
       :: . . .... : ::: .... .: ..  ::. :.:: ::...:: ::.::  :: .:.
NP_001 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
     110       120       130       140       150       160         

     180       190       200       210       220       230         
pF1KB7 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
       ::..:: :..: .   .: .   .. :::  :.:.                         
NP_001 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
     170       180       190        200       210       220        

     240       250       260       270       280       290         
pF1KB7 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
                                                                   
NP_001 IF                                                          
      230                                                          

>>NP_001129036 (OMIM: 140581) heat shock factor protein   (518 aa)
 initn: 630 init1: 630 opt: 649  Z-score: 418.4  bits: 86.9 E(85289): 1.5e-16
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (15-214:5-203)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
                     : :::::.:::.:: .  :...: :: .: :::: :..:::::.::
NP_001           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
                         10        20        30        40        50

               70        80        90        100       110         
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
       .::::.:::::::::::::::::: :..: ... :::  :::::: : .:...::: ..:
NP_001 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
               60        70         80        90       100         

     120       130       140       150       160       170         
pF1KB7 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
       :: . . .... : ::: .... .: ..  ::. :.:: ::...:: ::.::  :: .:.
NP_001 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
     110       120       130       140       150       160         

     180       190       200       210       220       230         
pF1KB7 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
       ::..:: :..: .   .: .   .. :::  :.:.                         
NP_001 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
     170       180       190        200       210       220        

     240       250       260       270       280       290         
pF1KB7 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
                                                                   
NP_001 PHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVE
      230       240       250       260       270       280        

>>NP_004497 (OMIM: 140581) heat shock factor protein 2 i  (536 aa)
 initn: 625 init1: 625 opt: 649  Z-score: 418.2  bits: 86.9 E(85289): 1.5e-16
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (15-214:5-203)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
                     : :::::.:::.:: .  :...: :: .: :::: :..:::::.::
NP_004           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
                         10        20        30        40        50

               70        80        90        100       110         
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
       .::::.:::::::::::::::::: :..: ... :::  :::::: : .:...::: ..:
NP_004 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
               60        70         80        90       100         

     120       130       140       150       160       170         
pF1KB7 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
       :: . . .... : ::: .... .: ..  ::. :.:: ::...:: ::.::  :: .:.
NP_004 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
     110       120       130       140       150       160         

     180       190       200       210       220       230         
pF1KB7 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
       ::..:: :..: .   .: .   .. :::  :.:.                         
NP_004 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
     170       180       190        200       210       220        

     240       250       260       270       280       290         
pF1KB7 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
                                                                   
NP_004 PHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVE
      230       240       250       260       270       280        




462 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:04:00 2016 done: Fri Nov  4 07:04:02 2016
 Total Scan time: 12.190 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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