Result of FASTA (omim) for pF1KB7261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7261, 196 aa
  1>>>pF1KB7261 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1260+/-0.000299; mu= 14.8828+/- 0.019
 mean_var=72.6176+/-14.535, 0's: 0 Z-trim(117.2): 46  B-trim: 0 in 0/55
 Lambda= 0.150506
 statistics sampled from 28916 (28962) to 28916 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.34), width:  16
 Scan time:  6.320

The best scores are:                                      opt bits E(85289)
NP_148983 (OMIM: 173430) platelet-derived growth f ( 196) 1313 293.6 1.3e-79
XP_011513720 (OMIM: 173430) PREDICTED: platelet-de ( 234) 1313 293.7 1.5e-79
NP_002598 (OMIM: 173430) platelet-derived growth f ( 211) 1293 289.3 2.9e-78
XP_011513718 (OMIM: 173430) PREDICTED: platelet-de ( 249) 1293 289.3 3.3e-78
XP_016867778 (OMIM: 173430) PREDICTED: platelet-de ( 224) 1159 260.2 1.7e-69
XP_011513721 (OMIM: 173430) PREDICTED: platelet-de ( 210) 1153 258.9 4.1e-69
XP_011513719 (OMIM: 173430) PREDICTED: platelet-de ( 241)  975 220.3   2e-57
XP_011513717 (OMIM: 173430) PREDICTED: platelet-de ( 256)  955 216.0 4.2e-56
NP_002599 (OMIM: 190040,213600,607174,607907,61548 ( 241)  500 117.1 2.2e-26
NP_148937 (OMIM: 190040,213600,607174,607907,61548 ( 226)  471 110.8 1.6e-24
NP_001230662 (OMIM: 601398) vascular endothelial g ( 188)  182 48.0 1.1e-05
NP_003368 (OMIM: 601398) vascular endothelial grow ( 207)  182 48.1 1.2e-05
NP_004460 (OMIM: 300091) vascular endothelial grow ( 354)  163 44.1 0.00031
NP_001280572 (OMIM: 601121) placenta growth factor ( 169)  153 41.7  0.0008
NP_002623 (OMIM: 601121) placenta growth factor is ( 170)  153 41.7  0.0008
NP_001193941 (OMIM: 601121) placenta growth factor ( 149)  150 41.0  0.0011
NP_005420 (OMIM: 601528,615907) vascular endotheli ( 419)  154 42.2  0.0014
XP_016863944 (OMIM: 608452) PREDICTED: platelet-de ( 310)  149 41.0  0.0023
XP_011530426 (OMIM: 608452) PREDICTED: platelet-de ( 334)  149 41.0  0.0025
NP_057289 (OMIM: 608452) platelet-derived growth f ( 345)  149 41.1  0.0025
NP_001165101 (OMIM: 192240,603933) vascular endoth ( 137)  139 38.6  0.0056
NP_001191313 (OMIM: 192240,603933) vascular endoth ( 171)  138 38.4  0.0077
NP_001165096 (OMIM: 192240,603933) vascular endoth ( 209)  138 38.5   0.009
NP_001165095 (OMIM: 192240,603933) vascular endoth ( 215)  138 38.5  0.0092
NP_001165099 (OMIM: 192240,603933) vascular endoth ( 147)  136 37.9  0.0093
NP_001165094 (OMIM: 192240,603933) vascular endoth ( 232)  138 38.5  0.0097


>>NP_148983 (OMIM: 173430) platelet-derived growth facto  (196 aa)
 initn: 1313 init1: 1313 opt: 1313  Z-score: 1550.0  bits: 293.6 E(85289): 1.3e-79
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)

               10        20        30        40        50        60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
              130       140       150       160       170       180

              190      
pF1KB7 TTSLNPDYREEDTDVR
       ::::::::::::::::
NP_148 TTSLNPDYREEDTDVR
              190      

>>XP_011513720 (OMIM: 173430) PREDICTED: platelet-derive  (234 aa)
 initn: 1313 init1: 1313 opt: 1313  Z-score: 1548.9  bits: 293.7 E(85289): 1.5e-79
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:39-234)

                                             10        20        30
pF1KB7                               MRTLACLLLLGCGYLAHVLAEEAEIPREVI
                                     ::::::::::::::::::::::::::::::
XP_011 RGRVAAARRPAGAPAPRPRLSSEQPAPRDAMRTLACLLLLGCGYLAHVLAEEAEIPREVI
       10        20        30        40        50        60        

               40        50        60        70        80        90
pF1KB7 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
       70        80        90       100       110       120        

              100       110       120       130       140       150
pF1KB7 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
      130       140       150       160       170       180        

              160       170       180       190      
pF1KB7 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
      190       200       210       220       230    

>>NP_002598 (OMIM: 173430) platelet-derived growth facto  (211 aa)
 initn: 1293 init1: 1293 opt: 1293  Z-score: 1526.1  bits: 289.3 E(85289): 2.9e-78
Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
              130       140       150       160       170       180

              190                     
pF1KB7 TTSLNPDYREEDTDVR               
       :::::::::::::                  
NP_002 TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
              190       200       210 

>>XP_011513718 (OMIM: 173430) PREDICTED: platelet-derive  (249 aa)
 initn: 1293 init1: 1293 opt: 1293  Z-score: 1525.1  bits: 289.3 E(85289): 3.3e-78
Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:39-231)

                                             10        20        30
pF1KB7                               MRTLACLLLLGCGYLAHVLAEEAEIPREVI
                                     ::::::::::::::::::::::::::::::
XP_011 RGRVAAARRPAGAPAPRPRLSSEQPAPRDAMRTLACLLLLGCGYLAHVLAEEAEIPREVI
       10        20        30        40        50        60        

               40        50        60        70        80        90
pF1KB7 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
       70        80        90       100       110       120        

              100       110       120       130       140       150
pF1KB7 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
      130       140       150       160       170       180        

              160       170       180       190                    
pF1KB7 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR              
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_011 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKP
      190       200       210       220       230       240        

XP_011 T
        

>>XP_016867778 (OMIM: 173430) PREDICTED: platelet-derive  (224 aa)
 initn: 1159 init1: 1159 opt: 1159  Z-score: 1368.5  bits: 260.2 E(85289): 1.7e-69
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 173 aa overlap (21-193:34-206)

                         10        20        30        40        50
pF1KB7           MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEI
                                     ::::::::::::::::::::::::::::::
XP_016 HSPRRGNLVLQAPQRPPTLLKNRGGEWGRPEEAEIPREVIERLARSQIHSIRDLQRLLEI
            10        20        30        40        50        60   

               60        70        80        90       100       110
pF1KB7 DSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQV
            70        80        90       100       110       120   

              120       130       140       150       160       170
pF1KB7 DPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVR
           130       140       150       160       170       180   

              180       190                     
pF1KB7 LEEHLECACATTSLNPDYREEDTDVR               
       :::::::::::::::::::::::                  
XP_016 LEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
           190       200       210       220    

>>XP_011513721 (OMIM: 173430) PREDICTED: platelet-derive  (210 aa)
 initn: 1153 init1: 1153 opt: 1153  Z-score: 1361.8  bits: 258.9 E(85289): 4.1e-69
Smith-Waterman score: 1153; 100.0% identity (100.0% similar) in 172 aa overlap (22-193:21-192)

               10        20        30        40        50        60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
                            :::::::::::::::::::::::::::::::::::::::
XP_011  MLISLLNQKLSAPSLPPRPSEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
     120       130       140       150       160       170         

              190                     
pF1KB7 TTSLNPDYREEDTDVR               
       :::::::::::::                  
XP_011 TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
     180       190       200       210

>>XP_011513719 (OMIM: 173430) PREDICTED: platelet-derive  (241 aa)
 initn: 975 init1: 975 opt: 975  Z-score: 1152.1  bits: 220.3 E(85289): 2e-57
Smith-Waterman score: 975; 97.9% identity (98.6% similar) in 146 aa overlap (51-196:96-241)

               30        40        50        60        70        80
pF1KB7 EEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPL
                                     : . ::::::::::::::::::::::::::
XP_011 GRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKRPL
          70        80        90       100       110       120     

               90       100       110       120       130       140
pF1KB7 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
         130       140       150       160       170       180     

              150       160       170       180       190      
pF1KB7 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
         190       200       210       220       230       240 

>>XP_011513717 (OMIM: 173430) PREDICTED: platelet-derive  (256 aa)
 initn: 955 init1: 955 opt: 955  Z-score: 1128.3  bits: 216.0 E(85289): 4.2e-56
Smith-Waterman score: 955; 97.9% identity (98.6% similar) in 143 aa overlap (51-193:96-238)

               30        40        50        60        70        80
pF1KB7 EEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPL
                                     : . ::::::::::::::::::::::::::
XP_011 GRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKRPL
          70        80        90       100       110       120     

               90       100       110       120       130       140
pF1KB7 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
         130       140       150       160       170       180     

              150       160       170       180       190          
pF1KB7 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR    
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_011 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESG
         190       200       210       220       230       240     

XP_011 KKRKRKRLKPT
         250      

>>NP_002599 (OMIM: 190040,213600,607174,607907,615483) p  (241 aa)
 initn: 519 init1: 395 opt: 500  Z-score: 594.7  bits: 117.1 E(85289): 2.2e-26
Smith-Waterman score: 500; 46.4% identity (68.3% similar) in 183 aa overlap (7-183:7-184)

               10        20        30        40        50          
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS--
             :.:  : ::  : ::   ::.:. : :.  .:.:. ::::::. :  : ::.  
NP_002 MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAE
               10        20        30        40        50          

       60         70        80        90          100       110    
pF1KB7 LDTSL-RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTS
       :: .. :.:.    . . . :    :   :.  : ::.   ::::: ..:: :  .: :.
NP_002 LDLNMTRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTN
      60        70        80            90       100       110     

          120       130       140       150       160       170    
pF1KB7 ANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEH
       ::::.:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:
NP_002 ANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDH
         120       130       140       150       160       170     

          180       190                                            
pF1KB7 LECACATTSLNPDYREEDTDVR                                      
       : : : :..                                                   
NP_002 LACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTAL
         180       190       200       210       220       230     

>>NP_148937 (OMIM: 190040,213600,607174,607907,615483) p  (226 aa)
 initn: 504 init1: 395 opt: 471  Z-score: 561.1  bits: 110.8 E(85289): 1.6e-24
Smith-Waterman score: 471; 46.7% identity (70.3% similar) in 165 aa overlap (25-183:10-169)

               10        20        30        40        50          
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS--
                               ::.:. : :.  .:.:. ::::::. :  : ::.  
NP_148                MFIMGLGDPIPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAE
                              10        20        30         40    

       60         70        80        90          100       110    
pF1KB7 LDTSL-RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTS
       :: .. :.:.    . . . :    :   :.  : ::.   ::::: ..:: :  .: :.
NP_148 LDLNMTRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTN
           50        60            70        80        90       100

          120       130       140       150       160       170    
pF1KB7 ANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEH
       ::::.:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:
NP_148 ANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDH
              110       120       130       140       150       160

          180       190                                            
pF1KB7 LECACATTSLNPDYREEDTDVR                                      
       : : : :..                                                   
NP_148 LACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTAL
              170       180       190       200       210       220




196 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:26:06 2016 done: Fri Nov  4 06:26:07 2016
 Total Scan time:  6.320 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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